Biología Molecular y Bioquímica de venenos de animales ponzoñosos
Bioprocesos con aplicaciones biotecnológicas y para la generación de medicamentos biotecnológicos
Bioquímica Estructural de Proteínas
Estructura, Función y Manipulación de Péptidos y Proteínas con énfasis en estudios electrofisiológicos
Estructura, Función y Manipulación de Péptidos y Proteínas con función antimicrobiana
Número de registros: 39
  • Activos
  • Vencidos
  • Estructura y función de componentes del veneno de alacranes, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2023 - 2025
  • Estructura y función de componentes del veneno de alacranes mexicanos, incluyendo análisis transcriptomica y proteomica, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2019 - 2021
  • Natural agonists of ryanodine receptors: structure-function relationship and antiarrhythmic properties, NATIONAL INSTITUTES OF HEALTH, 2018 - 2020
  • Genes y proteínas de alacranes: aislamiento y caracterización, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2016 - 2019
  • Proteómica y transcriptómica de las glándulas del veneno de alacranes, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2015 - 2019
  • Arácnidos de la biodiversidad mexicana y brasileña: purificación y caracterización de componentes del veneno, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2015 - 2017
  • Proteínas, péptidos y genes del veneno de alacranes y anticuerpos protectores, PRESUPUESTO UNAM, 2014 - 2020
  • Componentes del veneno de alacranes: aislamiento y caracterización, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2013 - 2016
  • Biomedicine for inwardly rectifying potassium channel, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2012 - 2015
  • Eventos moleculares asociados a la intoxicación por veneno de alacranes: un análisis por biología de sistemas, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2012 - 2015
  • Calcins as membrane-permeable ligands of ryanodine receptors, UNIVERSITY OF MICHIGAN, 2011 - 2016
  • Purificación y caracterización de componentes del veneno de arácnidos de la biodiversidad mexicana y brasileña, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2010 - 2013
  • Aislamiento y caracterización de componentes del veneno para alacranes, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2010 - 2012
  • Una nueva estrategia para generación de vacuna aviar, mediante el uso de anticuerpos contra receptores de células dendríticas, Instituto de Ciencia y Tecnología del Distrito Federal, 2009 - 2011
  • K+ channel blockers for malaria control, BILL & MELINDA GATES FOUNDATION, 2009 - 2010
  • Toxinas de alacrán y sintéticos análogos que afectan los canales de potasio responsables de las corrientes a del sistema nervioso central, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2009 - 2012
  • Desarrollo de mosquitos transgénicos resistentes a la transmisión de malaria y dengue, FONDO DE COOPERACIÓN INTERNACIONAL EN CIENCIA Y TECNOLOGÍA UNIÓN EUROPEA - MÉXICO, 2009 - 2012
  • Identificación y caracterización de nuevas toxinas de alacrán inhibidoras de canales iónicos de linfocitos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2008 - 2011
  • Caracterización química-funcional de componentes del veneno de alacranes, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2007 - 2009
  • Estudio del veneno de alacrán brasileño opisthacanthus cayaporum: caracterización química-funcional de sus péptidos y generación de una biblioteca de genes para su producción recombinante., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2006 - 2009
  • Eventos moleculares asociados a la intoxicación por veneno de alacranes: un análisis por biología de sistemas., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2006 - 2009
  • Análisis proteómico de venenos de alacranes mexicanos y latinoamericanos con miras a la identificación de nuevas toxinas que afectan canales iónicos de potasio, responsables de las corrientes tipo-a de células del cerebelo., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2006 - 2009
  • Toxinas, antibióticos y defensinas del veneno de alacranes con improtancia en salud pública., FONDO SECTORIAL DE INVESTIGACIÓN EN SALUD Y SEGURIDAD SOCIAL, 2006 - 2010
  • Producción de antígenos recombinantes para la obtención de faboterápicos útiles en el tratamiento contra la intoxicación causada por picadura de alacrán., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2005 - 2007
  • Identificación y caracterización de nuevas toxinas de alacrán inhibidoras de canales iónicos en linfocitos., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2004 - 2007
  • Ligandos naturales de venenos de arañas como herramientas para el estudio de receptores celulares., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2004 - 2005
  • Caracterización química y funcional de componentes del veneno y de la hemolinfa de alacranes., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2004 - 2006
  • Componentes del veneno de alacranes: ergtoxinas, defensinas y fosfolipasas, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2003 - 2006
  • Caracterización química- funcional de toxinas de arácnidos que actúan sobre canales iónicos de calico y potasio., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2002 - 2004
  • Aislamiento del veneno de alacranes y caracterización del papel fisiológico que juegan péptidos específicos en los canales iónicos voltaje y neurotransmisores dependientes., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2002 - 2003
  • Ligandos naturales de la biodiversidad mexicana para el desarrollo y diseño de nuevos fármacos., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2000 - 2002
  • Estructura de toxinas del veneno de alacrán y estudio de la interacción con canales iónicos., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2000 - 2003
  • Toxinas del veneno de alacranes; ergtoxina y canales de potasio, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1999 - 2002
  • Toxinas de alacrán: herramientas sitio-específico para el estudio de la excitabilidad de las membranas biológicas, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1999 - 2001
  • Aislamiento y caracterización de péptidos tóxicos de venenos de alacranes de baja california: preparación de un banco de cdn y clonaciòn de genes, DIRECCIÓN GENERAL DE INTERCAMBIO ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 1997
  • Estudio de la interacción de toxinas de alacranes con canales de potasio, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 1997 - 2000
  • Chemical and functional characterization of scorpion toxins, HOWARD HUGHES MEDICAL INSTITUTE, 1997 - 2001
  • Toxinas peptídicas de alacranes mexicanos como sondas para el estudio de las funciones de canales iónicos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1996 - 1998
  • Noxiustoxina y cn5 como modelos de toxinas del veneno de alacranes mexicanos que actúan sobre canales iónicos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1995 - 1998

Nivel D del PRIDE
Nivel Investigador Emérito del SNII
  • Doctorado, en Biofísica, Faculte des Sciences DOrsay-Universite de París, Francia (octubre 1968-marzo 1970)

  • Licenciatura, Historia Natural, Fac. de Filosofía de la Universidad Federal de Río Grande do Sul, Brasil (1966)

  • Premio Luis Elizondo, Tecnológico de Monterrey, 2017

  • Premio Heberto Castillo, Secretaria de Ciencia, Tecnologia y Innovación de la ciudad de Mexico, 2017

  • Premio Nacional de Ciencias, Gobierno Mexicano, 2016

  • Premio Redi, International Society on Toxinology, 2006

  • Investigador emérito, UNAM, 2005

  • Doctor Honoris Causa, Universidad de Debrecen, Hungría, 2005

  • Miembro de la Academia de Ciencias de America Latina, 1999

  • Premio Nacional de Investigación Básica, Fundación Glaxo-Wellcome, 1998

  • Howard Hughes Medical Institute International Research Scholar 1997-2001, 1997

  • Premio Nacional de Ciencias y Artes, Gobierno de la República, 1995

  • Premio de Investigacion Medica Dr. Jorge Rosenkran, 1994

  • Premio Universidad Nacional en el área de Ciencias Naturales, UNAM, 1993

  • Howard Hughes Medical Institute International Research Scholar 1991-1996, 1991

4 - Mendonza Luis,Rey Luis (2019). Síntesis química y predicción de estructura secundaria de Cn29, un péptido aislado del veneno del alacrán ?Centruroides noxius. Facultad de Ciencias Biológicas, Biólogo, Benemérita Universidad Autónoma de Puebla. *
8 - Amaro Estrada, Itzel (2015). Obtencion de anticuerpos de origen humano que neutralicen la toxina ts1 del alacran brasileno tityus serrulatus. Instituto de Biotecnologia, 68 paginas, Doctorado en Ciencias Bioquimicas, UNAM.
9 - Luna Ramirez,Karen Sofia (2014). Urodacus yaschenkoi, Autralian scorpion: phylogeny, venom characterization and pharmacology. Facultad de Medicina, Odontologia y Ciencias de la Salud, University of Melbourne. *
10 - Jimenez Vargas, Juana Maria (2012). Toxinas de alacran que afectan a canales de potasio del tipo herg1 . Instituto de Biotecnologia, Doctorado en Ciencias Biomedicas, UNAM.
12 - Rendon Anaya, Martha Rosalia (2011). Analisis del transcriptoma de la glandula de veneno del alacran Centruroides noxius Hoffmann . Instituto de Biotecnologia, x, 97 paginas, Maestria en Ciencias Bioquimicas, UNAM.
Asesor: Possani Postay, Lourival D., Herrera Estrella,Luis

13 - Espino Solis, Gerardo Pavel (2009). Desarrollo de anticuerpos contra integrinas de celulas dendriticas de caballo con miras a su aplicacion biotecnologica. Instituto de Biotecnologia, 28, [59] paginas, Doctorado en Ciencias Bioquimicas, UNAM.
14 - Jimenez Vargas, Juana Maria (2006). Expresion heterologa de genes que codifican para toxinas de alacran . Instituto de Biotecnologia, Maestria en Ciencias Bioquimicas, UNAM.
22 - Meyer,Lutz (2001). Characterization of the venom of the marine snail Conus delessertii. Diploma en Biologia, Química y Farmácia, Universidad Libre de Berlin. *
Asesor: Possani Postay, Lourival D., Hucho, Ferdinand , Heimer,Edgar

26 - Ferreira Batista,Cesar Vicente (1999). Péptidos antimicrobianos del anfíbio Brasileño Phyllomedusa distincta. Doctor en Ciencias Biológicas (Biología Molecular), Universidad de Brasilia. *
Asesor: Possani Postay,Lourival D., Bloch, Carlos

29 - Valdez Cruz, Norma Adriana (1998). Análisis morfológico del alacrán Centruroides exilicauda y caracterización de algunas de sus toxinas". Facultad de Ciencias Químicas, Licenciado en Químico Farmaco Biólogo, Universidad Autonoma de Baja California. *
Asesor: Possani Postay, Lourival D., Licea, Alexei F.

31 - Pardo Lopez, Liliana (1995). Secuenciación del cDNA que codifica para la toxina Helotermina del veneno de Heloderma horridum horridum. Facultad de Biología, Licenciado en Biología, Universidad Veracruzana. *
33 - Ramirez Navarro, Angelina (1994). Determinacion de las constantes de afinidad de toxinas del veneno de alacranes mexicanos a tejidos excitables : cerebro y musculo. Facultad de Medicina, Doctorado en Ciencias Biomedicas, UNAM. *
35 - Gurrola Briones, Georgina (1994). Caracterizacion funcional estructural de la noxiustoxina. Instituto de Biotecnologia, Doctorado en Investigacion Biomedica Basica, UNAM.
36 - Muñoz Garay,Roberto Carlos (1994). Determinación del efecto de la toxina 2 de Centruroides noxius sobre la proliferación in vitro de linfocitos murinos. Licenciado en Biología, Universidad Autónoma del Estado de Mexico. *
37 - Tapia Vieyra,Juana Virginia (1994). Determinación de la secuencia nucleotídica de cDNAs que codifican para toxinas del veneno de alacrán Centruroides noxius Hoffmann. Licenciado en Biología, Universidad Autónoma del Estado de México. *
38 - Vaca Dominguez, Luis Alfonso (1994). Uso de toxinas como sensores estructurales de canales de potasio. Facultad de Medicina, Doctorado en Ciencias Biomédicas, UNAM. *
40 - Cossio Bayugar, Raquel (1993). Aislamiento y caracterizacion de una fosfolipasa del veneno del alacran Hadrurus concolourus. Colegio de Ciencias y Humanidades, Unidad Academica de los Ciclos Profesional y de Posgrado, Licenciatura en Investigación Biomédica Básica, UNAM. *
43 - Fernández Aguilar,Juan Antonio (1992). Aislamiento y caracterización química de componentes tóxicos minoritarios del veneno del alacrán Centruroides limpidus limpidus (Alacrán de Guerrero). Médico Veterinario Zootecnista, Universidad Autónoma Agrária "Antonio Narro", Torreon, Coahuila. *
46 - Mocha Morales, Javier (1991). Caracterizacion quimica y funcional de la toxina helotermina del verano de Heloderna horridum. Facultad de Medicina, Doctorado en Ciencias Biomedicas, UNAM. *
48 - Villarreal Molina, Gilda Maria (1989). Purificación y marcaje de toxinas del alacrán Centruroides noxius para el estudio de canales iónicos de membranas excitables. Licenciatura en Investigación Biomédica Básica, UNAM. *
49 - Vaca Dominguez, Luis Alfonso (1989). Sintesis de peptidos correspondientes a la secuencia de la noxiustoxina : determinantes antigenicos y efectos sobre canales ionicos. Maestria en Investigacion Biomedica Basica, UNAM. *
51 - Mochca Morales, Javier (1988). Aislamiento y caracterizacion de una toxina del veneno del Heloderma horridum horridum. Maestro en Investigacion Biomedica Basica, UNAM. *
53 - Balderas Altamirano,Cipriano (1988). Aislamiento y caracterizacion de toxinas del alacrán de Morelos Centruroides limpidus limpidus (Karsch). Biólogo, Universidad Autonoma del Estado de Morelos. *
54 - Ramirez Navarro, Angelina (1987). Aislamiento y caracterizacion de las toxinas del veneno del alacran C. Limpidus tecomanus Hoffmann . Facultad de Medicina, Maestria en Ciencias Biomedicas, UNAM. *
55 - Dehesa Dávila,Manuel (1987). Aislamiento y caracterización de una toxina del veneno del alacrán Centruroides infamatus infamatus Koch. Maestro en Investigación Biomédicas, Universidad de Guanajuato, Léon. *
56 - Sanchez Garcia, Maria del Rocio (1986). Purificacion de toxinas del veneno del alacran Centruroides noxius Hoffmann 1932, por medio de inmunoadsorbentes. Facultad de Ciencias, Licenciatura en Biología, UNAM. *
58 - Colomer Gould, Veronica (1984). Obtencion de anticuerpos monoclonales en contra de toxinas del veneno de alacran centruroides noxius. Instituto de Investigaciones Biomedicas, Licenciatura en Investigacion Biomedica Basica, UNAM. *
Asesor: Possani, Lourival Domingos, Celis, Esteban

59 - Rode Sanchez, Gustavo Ricardo (1984). Aislamiento y caracterización de los componentes tóxicos del veneno del alacrán sudamericano Tityus serrulatus. Facultad de Química, Maestría en Ciencias (Bioquímica), UNAM. *
60 - Ramirez Avila, Guillermo Julio (1983). Aislamiento y caracterizacion de proteinasas del veneno de la serpiente mexicana crotalus molossus nigrescens (Gloyd) 1936. Facultad de Quimica, Maestro en Ciencias Quimicas (Bioquimica), UNAM. *
61 - Dent, Myrna Alexandra Roberta (1983). Aislamiento y caracterizacion quimica de diversas toxinas del veneno del alacran centruroides noxius hoffmann. Facultad de Química, Maestría en Ciencias Químicas (Bioquímica), UNAM. *
62 - Rode Sanchez, Gustavo Ricardo (1980). Contribucion al estudio de la glutamato descarboxilasa (GAD) de cerebro : Aspectos cineticos y problemas de purificacion . Facultad de Quimica, Quimico Farmaceutico Biologo, UNAM. *
63 - Alagon Cano, Alejandro (1980). Estudio sobre los venenos de varias especies zoologicas. Instituto de Investigacions Biomedicas, Maestria en Investigacion Biomedica Basica, UNAM. *
64 - Molinar Rode, Ricardo Alejandro (1979). Caracterizacion bioquimica del veneno de la serpiente mexicana bothrops asper . Facultad de Quimica, Quimico Farmaceutico Biologo, UNAM. *
65 - Dent, Myrna Alexandra Roberta (1979). Contribucion al estudio de las toxinas del veneno y ultraestructura del telson del alacran de Nayarit centruroides noxius hoffmann. Facultad de Ciencias, Licenciatura en Biología, UNAM. *
Total de publicaciones: 451
  • Tipo
  • Fecha
Open Access Artículo in press
66 - Bejarano-Mendoza,F.O., Gomez-Ramirez,I.V., Cortes-Guzman,A.J., Becerril,B., Possani,L.D., Cid-Uribe,J.I., Gonzalez-Santillan,E. (2025). Disparity among venom components, and morphometrics in Centruroides baergi Hoffmann, 1932, a medically relevant scorpion species from Mexico. Toxicon, Apr 23 [Online ahead of print], 108370.
Open Access Artículo
69 - Monteiro,I.S., Araujo,I.F.S., Camargos,T.S., Ortiz,E., Souza,A.C.B., Lima,J.D., Possani,L.D., Schwartz,E.F., Tibery,D.V. (2025). The First K(+)-Channel Blocker Described from Tityus fasciolatus Venom: The Purification, Molecular Cloning, and Functional Characterization of a-KTx4.9 (Tf5). Toxins (Basel), 17 (2), 96.
Open Access Artículo
71 - Gonzalez-Santillan,E., Valdez-Velazquez,L.L., Delgado-Hernandez,O., Cid-Uribe,J.I., Romero-Gutierrez,M.T., Possani,L.D. (2024). A multigene approach to identify the scorpion species (Arachnida: Scorpiones) of Colima, Mexico, with comments on their venom diversity. Revista Mexicana de Biodiversidad, 95, e955373.
Open Access Artículo
74 - Garcia-Villalvazo,P.E, Jimenez-Vargas,J.M, Lino-Lopez,G.J, Meneses,E.P, Bermudez-Guzman,M.J, Barajas-Saucedo,C.E, Delgado-Enciso,I., Possani,L.D, Valdez-Velazquez,L.L (2023). Unveiling the Protein Components of the Secretory-Venom Gland and Venom of the Scorpion Centruroides possanii (Buthidae) through Omic Technologies. Toxins (Basel), 15 (8), 498.
Artículo
76 - Ibarra-Vega,R., Jimenez-Vargas,J.M., Pineda-Contreras,A., Martinez-Martinez,F.J., Barajas-Saucedo,C.E., Garcia-Ortega,H., Magana-Vergara,N.E., Possani,L.D., Corzo,G., Gaitan-Hinojosa,M.A., Vazquez-Vuelvas,O.F., Zamudio,F., Valdez-Velazquez,L.L. (2023). Indolealkylamines in the venom of the scorpion Thorellius intrepidus. Toxicon, 233, 107232.
Artículo
77 - Lopez-Giraldo,E., Carrillo,E., Titaux-Delgado,G., Cano-Sanchez,P., Colorado,A., Possani,L.D., Rio-Portilla,F.D. (2023). Structural and functional studies of scorpine: A channel blocker and cytolytic peptide. Toxicon, 222, 106985 .
Artículo
80 - Salazar,M.H., Ortiz,M.H., Encarnacion,S., Zamudio,F., Possani,L.D., Cleghorn,J., Moran,M., Acosta,H., Corzo,G. (2023). A proteomic overview of the major venom components from Tityus championi from Panama. Toxicon, 227, 107082.
Artículo
83 - Bermudez-Guzman,M.J., Jimenez-Vargas,J.M., Possani,L.D., Zamudio,F., Ororzco-Gutierrez,G., Oceguera-Contreras,E., Enriquez-Vara,J.N, Vazquez-Vuelvas,O.F., Garcia-Villalvazo,P.E., Valdez-Velazquez,L.L. (2022). Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus. Toxicon, 206, 90-102.
Open Access Artículo
84 - Csoti,A., Najera-Meza,R.C., Bogar,F., Tajti,G., Szanto,T.G., Varga,Z., Gurrola,G.B., Toth,G.K., Possani,L.D., Panyi,G. (2022). sVmKTx, a transcriptome analysis-based synthetic peptide analogue of Vm24, inhibits Kv1.3 channels of human T cells with improved selectivity. Biochemical Pharmacology, 199, 115023.
Open Access Artículo
85 - Delgado-Prudencio,G., Cid-Uribe,J.I., Morales,J.A., Possani,L.D., Ortiz,E., Romero-Gutierrez,T. (2022). The Enzymatic Core of Scorpion Venoms. Toxins, 14 (4), 248.
Open Access Artículo
86 - Espinoza-Duarte,M.R., Ortega-Ochoa,C., Baca-Ramirez,A., Possani,L.D., Espino-Solis,G.P. (2022). Flow cytometry analysis of CD11c-positive peripheral blood mononuclear cells in horses. Veterinary Immunology and Immunopathology, 253 (November), 110504.
Artículo
87 - Naseem,M.U., Carcamo-Noriega,E., Borrego,J., Szanto,T.G., Zamudio,F.Z., Delgado-Prudencio,G., Possani,L.D., Panyi,G. (2022). Cm28, a scorpion toxin having a unique primary structure, inhibits KV1.2 and KV1.3 with high affinity. Journal of General Physiology, 154 (8), e202213146.
Artículo
91 - Alamilla,J., Jimenez-Vargas,J.M., Galvan-Hernandez,A.R., Reyes-Mendez,M.E., Bermudez-Guzman,M.J., Restano-Cassulini,R., Olamendi-Portugal,T., Zamudio,F.Z., Possani,L.D., Valdez-Velazquez,L.L. (2021). Toxin Ct1a, from venom of Centruroides tecomanus, modifies the spontaneous firing frequency of neurons in the suprachiasmatic nucleus. Toxicon, 197, 114-125.
Artículo
94 - Lopes,K.S., Torres Quintanilha,M.V., Barros de Souza,A.C., Zamudio-Zuniga,F., Possani,L.D., Mortari,M.R. (2021). Antiseizure potential of peptides from the venom of social wasp Chartergellus communis against chemically-induced seizures. Toxicon, 194, 23.
Open Access Artículo
96 - Rodriguez-Ravelo,R., Ruiz-Urquiola,A., Possani-Postay,L.D., Morris-Quevedo,H.J., Rodriguez-Ravelo,M., Espinosa-Lopez,G. (2021). Variation of cytochrome oxidase-I gene and venom proteins of Rhopalurus junceus populations in the Moanicum sector: Pharmacological implications. Journal of Pharmacy and Pharmacognosy Research, 9 (1), 1-12.
Artículo
97 - Vargas-Jaimes,L., Rodriguez,M.C., Argotte-Ramos,R., Juarez-Gonzalez,V.R., Pastor,N., Cesa-Luna,C., Possani,L.D., Quintero-Hernandez,V. (2021). Recombinant C-Terminal Domains from Scorpine-like Peptides Inhibit the Plasmodium berghei Ookinete Development In Vitro. International Journal of Peptide Research and Therapeutics, 27, 817-829.
Revisión
99 - Cid-Uribe,J.I., Veytia-Bucheli,J.I., Romero-Gutierrez,T., Ortiz,E., Possani,L.D. (2020). Scorpion venomics: a 2019 overview. Expert Review of Proteomics, 17 (1), 67-83.
Artículo
100 - Cota-Arce,J.M., Zazueta-Favela,D., Diaz-Castillo,F., Jimenez,S., Bernaldez-Sarabia,J., Caram-Salas,N.L., Dan,K.W.L., Escobedo,G., Licea-Navarro,A.F., Possani,L.D., De Leon-Nava,M.A. (2020). Venom components of the scorpion Centruroides limpidus modulate cytokine expression by T helper lymphocytes: Identification of ion channel-related toxins by mass spectrometry. International Immunopharmacology, 84, 106505.
Artículo
101 - El-Bitar, A. M. H., Sarhan, M., Abdel-Rahman, M. A., Quintero-Hernandez, V., Aoki-Utsubo, C., Moustafa, M. A., Possani, L. D., Hotta, H. (2020). Smp76, a Scorpine-Like Peptide Isolated from the Venom of the Scorpion Scorpio maurus palmatus, with a Potent Antiviral Activity Against Hepatitis C Virus and Dengue Virus. International Journal of Peptide Research and Therapeutics, 26, 811-821.
Artículo
Artículo
105 - Luna-Ramirez,K., Csoti,A., McArthur,J.R., Chin,Y.K.Y., Anangi,R., Najera,R.D.C., Possani,L.D., King,G.F., Panyi,G., Yu,H., Adams,D.J., Finol-Urdaneta,R.K. (2020). Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom. Biochemical Pharmacology, 174, 113782.
Artículo
106 - Mourao,C.B.F., Brand,G.D., Fernandes,J.P.C., Prates,M.V., Bloch,C., Barbosa,J.A.R.G., Freitas,S.M., Restano-Cassulini,R., Possani,L.D., Schwartz,E.F. (2020). Head-to-Tail Cyclization after Interaction with Trypsin: A Scorpion Venom Peptide that Resembles Plant Cyclotides. Journal of Medicinal Chemistry, 63 (17), 9500?951.
Open Access Artículo
Artículo
Open Access Artículo
110 - Bernaldez-Sarabia,J., Figueroa-Montiel,A., Duenas,S., Cervantes-Luevano,K., Beltran,J.A., Ortiz,E., Jimenez,S., Possani,L.D., Paniagua-Solis,J.F., Gonzalez-Canudas,J., Licea-Navarro,A. (2019). The Diversified O-Superfamily in Californiconus californicus Presents a Conotoxin with Antimycobacterial Activity. Toxins (Basel), 11 (2), E128.
Artículo
111 - Carcamo-Noriega,E.N., Sathyamoorthi,S., Banerjee,S., Gnanamani,E., Mendoza-Trujillo,Monserrat, Mata-Espinosa,D., Hernandez-Pando,R., Veytia-Bucheli,J.I., Possani,L.D., Zare,R.N. (2019). 1,4-Benzoquinone antimicrobial agents against Staphylococcus aureus and Mycobacterium tuberculosis derived from scorpion venom. Proceedings of the National Academy of Sciences, 116 (26), 201812334, 12642-12647.
Open Access Artículo
120 - Santibanez-Lopez,C.E., Graham,M.R., Sharma,P.P., Ortiz,E., Possani,L.D. (2019). Hadrurid Scorpion Toxins: Evolutionary Conservation and Selective Pressures. Toxins (Basel), 11 (11), E637, E637.
Open Access Artículo
Artículo
122 - Banerjee, S., Gnanamani, E., Lynch, S.R., Zamudio-Zuniga, F., Jimenez-Vargas, J.M., Possani, L.D., Zare, R.N. (2018). An Alkaloid from Scorpion Venom: Chemical Structure and Synthesis. Journal of Natural Products, 81 (8), 1899-1904.
Artículo
130 - Salazar, M.H., Arenas, I., Corrales-Garcia, L.L., Miranda, R., Velez, S., Sanchez, J., Mendoza, K., Cleghorn, J., Zamudio, F.Z., Castillo, A., Possani, L.D., Corzo, G., Acosta, H. (2018). Venoms of Centruroides and Tityus species from Panama and their main toxic fractions. Toxicon, 141, 79-87.
Revisión
137 - Jimenez-Vargas, J.M., Possani, L.D., Luna-Ramirez, K. (2017). Arthropod toxins acting on neuronal potassium channels. Neuropharmacology, 127, 139-160.
Artículo
138 - Lopes, K.S., Campos, G.A.A., Camargo, L.C., de Souza, A.C.B., Ibituruna, B.V., Magalhaes, A.C.M., da Rocha, L.F., Garcia, A.B., Rodrigues, M.C., Ribeiro, D.M., Costa, M.C., Lopez, M.H.M., Nolli, L.M., Zamudio-Zuniga, F., Possani, L.D., Schwartz, E.F., Mortari, M.R. (2017). Characterization of two peptides isolated from the venom of social wasp Chartergellus communis (Hymenoptera: Vespidae): Influence of multiple alanine residues and C-terminal amidation on biological effects. Peptides, 95, 84-93.
Open Access Artículo
141 - Restano-Cassulini, R., Garcia, W., Paniagua-Solis, J.F., Possani, L.D. (2017). Antivenom Evaluation by Electrophysiological Analysis. Toxins (Basel), 9 (3), 74.
Artículo
145 - Vargas-Jaimes, L., Xiao, L., Zhang, J., Possani, L.D., Valdivia, H.H., Quintero-Hernandez, V. (2017). Recombinant expression of Intrepicalcin from the scorpion Vaejovis intrepidus and its effect on skeletal ryanodine receptors. Biochimica et Biophysica Acta (BBA) - General Subjects, 1861 (4), 936-946.
Open Access Artículo
146 - Figueroa-Montiel,A., Ramos,M.A., Mares,R.E., Duenas,S., Pimienta,G., Ortiz,E., Possani,L.D., Licea-Navarro,A.F. (2016). In Silico Identification of Protein Disulfide Isomerase Gene Families in the De Novo Assembled Transcriptomes of Four Different Species of the Genus Conus. PLoS ONE, 11 (2), e0148390.
Revisión
147 - Luna-Martinez,K., Jimenez-Vargas,J.M., Possani,L.D. (2016). Scorpine-Like Peptides. Single Cell Biology, 5 (138).
Artículo
149 - Osnaya-Romero N., Acosta-Saavedra,L.C., Goytia-Acevedo,R., Lares-Asseff,I., Basurto-Celaya,G., Perez-Guille,G., Possani,L.D., Calderon-Aranda,E.S. (2016). Serum level of scorpion toxins, electrolytes and electrocardiogram alterations in Mexican children envenomed by scorpion sting. Toxicon, 122, 103-108.
Open Access Revisión
153 - Santibanez-Lopez,C.E., Francke,O.F., Ureta,C., Possani,L.D. (2016). Scorpions from Mexico: From Species Diversity to Venom Complexity. Toxins (Basel), 8 (1).
Artículo
154 - Valdez-Velazquez,L.L., Romero-Gutierrez,M.T., Delgado-Enciso,I., Dobrovinskaya,O., Melnikov,V., Quintero-Hernandez,V., Ceballos-Magana,S.G., Gaitan-Hinojosa,M.A., Coronas,F.I., Puebla-Perez,A.M., Zamudio,F., De la Cruz-Garcia,I, Vazquez-Vuelvas,O.F., Soriano-Hernandez,A.D., Possani,L.D. (2016). Comprehensive analysis of venom from the scorpion Centruroides tecomanus reveals compounds with antimicrobial, cytotoxic, and insecticidal activities. Toxicon, 118, 95-103.
Artículo
155 - Xiao,L., Gurrola,G.B., Zhang,J., Valdivia,C.R., SanMartin,M., Zamudio,F.Z., Zhang,L., Possani,L.D., Valdivia,H.H. (2016). Structure-function relationships of peptides forming the calcin family of ryanodine receptor ligands. Journal of General Physiology, 147 (5), 375-394.
Artículo
156 - Zhang,H., Du,M., Xie,J., Liu,X., Sun,J., Wang,W., Xin,X., Possani,L.D., Yea,K., Lerner,R.A. (2016). Autocrine-Based Selection of Drugs that Target Ion Channels from Combinatorial Venom Peptide Libraries. Angewandte Chemie International Edition, 55 (32), 9306-9310.
Artículo
158 - Espino-Solis,G.P., Quintero-Hernandez,V., Olvera-Rodriguez,A., Calderon-Amador,J., Pedraza-Escalona,M., Licea-Navarro,A., Flores-Romo,L., Possani,L.D. (2015). Novel monoclonal antibody against alphaX subunit from horse CD11c/CD18 integrin. Veterinary Immunology and Immunopathology, 164 (3-4), 220-226.
Artículo
160 - Okada,M., Corzo,G., Romero-Perez,G.A., Coronas,F., Matsuda,H., Possani,L.D. (2015). A pore forming peptide from spider Lachesana sp. venom induced neuronal depolarization and pain. Biochimica et Biophysica Acta (BBA) - General Subjects, 1850 (4), 657-666.
Open Access Revisión
161 - Ortiz,E., Possani,L.D. (2015). The unfulfilled promises of scorpion insectotoxins. Journal of Venomous Animals and Toxins Including Tropical Diseases, 21, 16.
Revisión
Artículo
169 - Luna-Ramirez,K., Sani,M.A., Silva-Sanchez,J., Jimenez-Vargas,J.M., Reyna-Flores,F., Winkel,K.D., Wright,C.E., Possani,L.D., Separovic,F. (2014). Membrane Interactions and Biological Activity of Antimicrobial Peptides from Australian Scorpion. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1838 (9), 2140-2148.
Artículo
170 - Ortiz,E., Rendon-Anaya,M., Rego,S.C., Schwartz,E.F., Possani,L.D. (2014). Antarease-like Zn-metalloproteases are ubiquitous in the venom of different scorpion genera. Biochimica et Biophysica Acta (BBA) - General Subjects, 1840 (6), 1738-1746.
Artículo
172 - Picco,C., Corzo,G., Possani,L.D., Prestipino,G. (2014). Interaction of the scorpion toxin Discrepin with Kv4.3 channels and A-type K channels in cerebellum granular cells. Biochimica et Biophysica Acta (BBA) - General Subjects, 1840 (9), 2744-2751.
Artículo
Artículo; Actas Paper
176 - Aguilar,M.B., Ortiz,E., Kaas,Q., Lopez-Vera,E., Becerril,B., Possani,L.D., de la Cotera,E.P. (2013). Precursor De13.1 from Conus delessertii defines the novel G gene superfamily. Peptides, 41, 17-20.
Open Access Artículo
177 - Bernaldez,J., Roman-Gonzalez,S.A., Martinez,O., Jimenez,S., Vivas,O., Arenas,I., Corzo,G., Arreguin,R., Garcia,D.E., Possani,L.D., Licea,A. (2013). A Conus regularis Conotoxin with a Novel Eight-Cysteine Framework Inhibits CaV2.2 Channels and Displays an Anti-Nociceptive Activity. Marine Drugs, 11 (4), 1188-1202.
Artículo
179 - Deuis,J.R., Zimmermann,K., Romanovsky,A.A., Possani,L.D., Cabot,P.J., Lewis,R.J., Vetter,I. (2013). An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Na1.6 in peripheral pain pathways. Pain, 154 (9), 1749-1757.
Artículo
180 - Garcia,F., Villegas,E., Espino-Solis,G.P., Rodriguez,A., Paniagua-Solis,J.F., Sandoval-Lopez,G., Possani,L.D., Corzo,G. (2013). Antimicrobial peptides from arachnid venoms and their microbicidal activity in the presence of commercial antibiotics. Journal of Antibiotics, 66 (1), 3-10.
Artículo
182 - Mourao,C.B., Heghinian,M.D., Barbosa,E.A., Mari,F., Bloch,C.,Jr., Restano-Cassulini,R., Possani,L.D., Schwartz,E.F. (2013). Characterization of a novel peptide toxin from Acanthoscurria paulensis spider venom: a distinct cysteine assignment into the HWTX-II family. Biochemistry, 52 (14), 2440-2452.
Open Access Artículo
186 - Rodriguez-Ravelo,R., Coronas,F.I., Zamudio,F.Z., Gonzalez-Morales,L., Lopez,G.E., Urquiola,A.R., Possani,L.D. (2013). The Cuban scorpion Rhopalurus junceus (Scorpiones, Buthidae): component variations in venom samples collected in different geographical areas. Journal of Venomous Animals and Toxins Including Tropical Diseases, 19 (1), 13.
Artículo
187 - Sanchez-Vasquez,L., Silva-Sanchez,J., Jimenez-Vargas,J.M., Rodriguez-Romero,A., Munoz-Garay,C., Rodriguez,M.C., Gurrola,G.B., Possani,L.D. (2013). Enhanced antimicrobial activity of novel synthetic peptides derived from vejovine and hadrurin. Biochimica et Biophysica Acta (BBA) - General Subjects, 1830 (6), 3427-3436.
Artículo
188 - Schwartz,E.F., Bartok,A., Schwartz,C.A., Papp,F., Gomez-Lagunas,F., Panyi,G., Possani,L.D. (2013). OcyKTx2, a new K-channel toxin characterized from the venom of the scorpion Opisthacanthus cayaporum. Peptides, 46, 40-46.
Open Access Artículo
Open Access Artículo
Artículo
195 - Gurrola,G.B., Hernandez-Lopez,R.A., Rodriguez de la Vega,R.C., Varga,Z., Batista,C.V., Salas-Castillo,S.P., Panyi,G., del Rio-Portilla,F., Possani,L.D. (2012). Structure, function and chemical synthesis of Vaejovis mexicanus peptide 24: a novel potent blocker of Kv1.3 potassium channels of human T lymphocytes. Biochemistry, 51 (19), 4049-4061.
Open Access Artículo
202 - Saucedo,A.L., Flores-Solis,D., Rodriguez de la Vega,R.C., Ramirez-Cordero,B., Hernandez-Lopez,R., Cano-Sanchez,P., Noriega-Navarro,R., Garcia-Valdes,J., Coronas-Valderrama,F., de Roodt,A., Brieba,L.G., Possani,L.D., del Rio-Portilla,F. (2012). New tricks of an old pattern: structural versatility of scorpion toxins with common cysteine spacing. Journal of Biological Chemistry, 287 (15), 12321-12330.
Artículo
203 - Saucedo,A.L., Del Rio,F., Picco,C., Estrada,G., Prestipino,G., Possani,L.D., Delepierre,M., Corzo,G. (2012). Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion suffusus, and their effects on Nav1.5 Sodium channels. Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1824 (3), 478-487.
Artículo
205 - Varga,Z., Gurrola-Briones,G., Papp,F., Rodriguez de la Vega,R.C., Pedraza-Alva,G., Tajhya,R.B., Gaspar,R., Cardenas,L., Rosenstein,Y., Beeton,C., Possani,L.D., Panyi,G. (2012). Vm24, a Natural Immunosuppressant Peptide Potently and Selectively Blocks Kv1.3 Potassium Channels of Human T Cells. Molecular Pharmacology, 82 (3), 372-382.
Artículo
206 - Wang,X., Jimenez-Vargas,J.M., Xu,C., Possani,L.D., Zhu,S. (2012). Positive selection-guided mutational analysis revealing two key functional sites of scorpion ERG K(+) channel toxins. Biochemical and Biophysical Research Communications, 429 (1-2), 111-116.
Artículo
208 - Camargos,T.S., Restano-Cassulini,R., Possani,L.D., Peigneur,S., Tytgat,J., Schwartz,C.A., de Freitas,S.M., Schwartz,E.F. (2011). The new kappa-KTx 2.5 from the scorpion Opisthacanthus cayaporum. Peptides, 32 (7), 1509-1517.
Revisión
Artículo
219 - de Roodt,A.R., Coronas,F.I., Lago,N., Gonzalez,M.E., Laskowicz,R.D., Beltramino,J.C., Saavedra,S., Lopez,R.A., Reati,G., Vucharchuk,M.G., Bazan,E., Varni,L., Salomon,O.D., Possani,L.D. (2010). General biochemical and immunological characterization of the venom from the scorpion Tityus trivittatus of Argentina. Toxicon, 55 (2-3), 307-319.
Open Access Artículo
Open Access Artículo
221 - Redaelli,E., Restano-Cassulini,R., Fuentes-Silva,D., Clement,H., Schiavon,E., Zamudio,F.Z., Odell,G., Arcangeli,A., Clare,J.J., Alagon,A., Rodriguez de la Vega,R.C., Possani,L.D., Wanke,E. (2010). Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels. Journal of Biological Chemistry, 285 (6), 4130-4142 .
Artículo; Actas Paper
222 - Rodriguez de la Vega,R.C., Schwartz,E.F., Possani,L.D. (2010). Mining on scorpion venom biodiversity. Toxicon, 56 (7), 1155-1161.
Artículo
224 - Zhu,S., Gao,B., Aumelas,A., Rodriguez,M.D., Lanz-Mendoza,H., Peigneur,S., Diego-Garcia,E., Martin-Eauclaire,M.F., Tytgat,J., Possani,L.D. (2010). MeuTXKbeta1, a scorpion venom-derived two-domain potassium channel toxin-like peptide with cytolytic activity. Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1804 (4), 872-883.
Artículo
225 - Corzo,G., Bernard,C., Clement,H., Villegas,E., Bosmans,F., Tytgat,J., Possani,L.D., Darbon,H., Alagon,A. (2009). Insecticidal peptides from the theraposid spider Brachypelma albiceps: A NMR-based model of Ba2. Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1794 (8), 1190-1196.
Artículo
226 - Corzo,G., Prochnicka-Chalufour,A., Garcia,B.I., Possani,L.D., Delepierre,M. (2009). Solution structure of Cn5, a crustacean toxin found in the venom of the scorpions Centruroides noxius and Centruroides suffusus suffusus. Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1794 (11), 1591-1598.
Artículo
Artículo
229 - Espino-Solis,G.P., Calderon-Amador,J., Calderon-Aranda,E.S., Licea,A.F., Donis-Maturano,L., Flores-Romo,L., Possani,L.D. (2009). Rational design of synthetic peptides to generate antibodies that recognize in situ CD11c+ putative dendritic cells in horse lymph nodes. Veterinary Immunology and Immunopathology, 132 (2-4), 181-190.
Artículo
233 - Kauferstein,S., Kendel,Y., Nicke,A., Coronas,F.I., Possani,L.D., Favreau,P., Krizaj,I., Wunder,C., Kauert,G., Mebs,D. (2009). New conopeptides of the D-superfamily selectively inhibiting neuronal nicotinic acetylcholine receptors. Toxicon, 54 (3), 295-301.
Artículo
234 - Papp,F., Batista,C.V., Varga,Z., Herceg,M., Roman-Gonzalez,S.A., Gaspar,R., Possani,L.D., Panyi,G. (2009). Tst26, a novel peptide blocker of Kv1.2 and Kv1.3 channels from the venom of Tityus stigmurus. Toxicon, 54 (4), 379-389.
Revisión
235 - Prestipino,G., Corzo,G., Romeo,S., Murgia,A.R., Zanardi,I., Gurrola,G., Possani,L.D. (2009). Scorpion toxins that block transient currents (IA) of rat cerebellum granular cells. Toxicology Letters, 187 (1), 1-9.
Artículo
236 - Schwartz,E.F., Capes,E.M., Diego-Garcia,E., Zamudio,F.Z., Fuentes,O., Possani,L.D., Valdivia,H.H. (2009). Characterization of hadrucalcin, a peptide from Hadrurus gertschi scorpion venom with pharmacological activity on ryanodine receptors. British Journal of Pharmacology, 157 (3), 392-403.
Artículo
237 - Silva,E.C., Camargos,T.S., Maranhao,A.Q., Silva-Pereira,I., Silva,L.P., Possani,L.D., Schwartz,E.F. (2009). Cloning and characterization of cDNA sequences encoding for new venom peptides of the Brazilian scorpion Opisthacanthus cayaporum. Toxicon, 54 (3), 252-261.
Artículo
238 - Abdel-Mottaleb,Y., Corzo,G., Martin-Eauclaire,M.F., Satake,H., Ceard,B., Peigneur,S., Nambaru,P., Bougis,P.E., Possani,L.D., Tytgat,J. (2008). A common "hot spot" confers hERG blockade activity to alpha-scorpion toxins affecting K(+) channels. Biochemical Pharmacology, 76 (6), 805-815.
Artículo
239 - Carballar-Lejarazu,R., Rodriguez,M.H., De La Cruz Hernandez-Hernandez,F., Ramos-Castaneda,J., Possani,L.D., Zurita-Ortega,M., Reynaud-Garza,E., Hernandez-Rivas,R., Loukeris,T., Lycett,G., Lanz-Mendoza,H. (2008). Recombinant scorpine: a multifunctional antimicrobial peptide with activity against different pathogens. Cellular and Molecular Life Sciences, 65 (19), 3081-3092.
Artículo
242 - Diego-Garcia,E., Abdel-Mottaleb,Y., Schwartz,E.F., de la Vega RC, Tytgat,J., Possani,L.D. (2008). Cytolytic and K(+) channel blocking activities of beta-KTx and scorpine-like peptides purified from scorpion venoms. Cellular and Molecular Life Sciences, 65 (1), 187-200.
Artículo
Artículo
245 - Petricevich,V.L., Reynaud,E., Cruz,A.H., Possani,L.D. (2008). Macrophage activation, phagocytosis and intracellular calcium oscillations induced by scorpion toxins from Tityus serrulatus. Clinical and Experimental Immunology, 154 (3), 415-423.
Artículo
247 - Romeo,S., Corzo,G., Vasile,A., Satake,H., Prestipino,G., Possani,L.D. (2008). A positive charge at the N-terminal segment of Discrepin increases the blocking effect of K(+) channels responsible for the I(A) currents in cerebellum granular cells. Biochimica et Biophysica Acta (BBA) - General Subjects, 1780 (4), 750-755.
Artículo
248 - Schwartz,E.F., Camargos,T.S., Zamudio,F.Z., Silva,L.P., Bloch,C.,Jr., Caixeta,F., Schwartz,C.A., Possani,L.D. (2008). Mass spectrometry analysis, amino acid sequence and biological activity of venom components from the Brazilian scorpion Opisthacanthus cayaporum. Toxicon, 51 (8), 1499-1508.
Artículo
Artículo
252 - Estrada,G., Garcia,B.I., Schiavon,E., Ortiz,E., Cestele,S., Wanke,E., Possani,L.D., Corzo,G. (2007). Four disulfide-bridged scorpion beta neurotoxin CssII: Heterologous expression and proper folding in vitro. Biochimica et Biophysica Acta (BBA) - General Subjects, 1770 (8), 1161-1168.
Artículo
253 - Lopez-Vera,E., Aguilar,M.B., Schiavon,E., Marinzi,C., Ortiz,E., Restano-Cassulini,R., Batista,C.V.F., Possani,L.D., Heimer de la Cotera,E.P., Peri,F., Becerril,B., Wanke,E. (2007). Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors. Febs Journal, 274 (15), 3972-3985.
Artículo
Artículo
259 - Abdel-Mottaleb,Y., Coronas,F.V., de Roodt,A.R., Possani,L.D., Tytgat,J. (2006). A novel toxin from the venom of the scorpion Tityus trivittatus, is the first member of a new alpha-KTX subfamily. FEBS Letters, 580 (2), 592-596.
Artículo
260 - Barona,J., Batista,C.V., Zamudio,F.Z., Gomez-Lagunas,F., Wanke,E., Otero,R., Possani,L.D. (2006). Proteomic analysis of the venom and characterization of toxins specific for Na(+)- and K(+)-channels from the Colombian scorpion Tityus pachyurus. Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1764 (1), 76-84.
Artículo
261 - Batista,C.V., D'Suze,G., Gomez-Lagunas,F., Zamudio,F.Z., Encarnacion,S., Sevcik,C., Possani,L.D. (2006). Proteomic analysis of Tityus discrepans scorpion venom and amino acid sequence of novel toxins. Proteomics, 6 (12), 3718-3727.
Revisión
264 - Panyi,G., Possani,L.D., Rodriguez de la Vega,R.C., Gaspar,R., Varga,Z. (2006). K+ Channel Blockers: Novel Tools to Inhibit T Cell Activation Leading to Specific Immunosuppression. Current Pharmaceutical Design, 12 (18), 2199-2220.
Artículo
265 - Prochnicka-Chalufour,A., Corzo,G., Satake,H., Martin-Eauclaire,M.F., Murgia,A.R., Prestipino,G., D'Suze,G., Possani,L.D., Delepierre,M. (2006). Solution Structure of Discrepin, a New K(+)-Channel Blocking Peptide from the alpha-KTx15 Subfamily(,). Biochemistry, 45 (6), 1795-1804.
Artículo; Actas Paper
266 - Restano-Cassulini,R., Korolkova,Y.V., Diochot,S., Gurrola,G., Guasti,L., Possani,L., Lazdunski,M., Grishin,E., Arcangeli,A., Wanke,E. (2006). Species Diversity and Peptide Toxins Blocking Selectivity of ERG Subfamily K+ Channels in CNS. Molecular Pharmacology, 69 (5), 1673-1683.
Open Access Artículo
Artículo
268 - Schwartz,E.F., Schwartz,C.A., Gomez-Lagunas,F., Zamudio,F.Z., Possani,L.D. (2006). HgeTx1, the first K(+)-channel specific toxin characterized from the venom of the scorpion Hadrurus gertschi Soleglad. Toxicon, 48 (8), 1046-1053.
Artículo
269 - Aguilar,M.B., Lopez-Vera,E., Ortiz,E., Becerril,B., Possani,L.D., Olivera,B.M., Heimer de la Cotera,E.P. (2005). A Novel Conotoxin from Conus delessertii with Posttranslationally Modified Lysine Residues. Biochemistry, 44 (33), 11130-11136.
Artículo
Artículo
272 - Diego-Garcia,E., Batista,C.V., Garcia-Gomez,B.I., Lucas,S., Candido,D.M., Gomez-Lagunas,F., Possani,L.D. (2005). The Brazilian scorpion Tityus costatus Karsch: genes, peptides and function. Toxicon, 45 (3), 273-283.
Revisión
273 - Gazarian,K.G., Gazarian,T., Hernandez,R., Possani,L.D. (2005). Immunology of scorpion toxins and perspectives for generation of anti-venom vaccines. Vaccine, 23 (26), 3357-3368.
Artículo
277 - Possani,L.D. (2005). Insecticidal peptide from scorpion venom. Industrial Bioprocessing, 27 (2), 9-10.
Carta
280 - Rodriguez de la Vega,R.C., Possani,L.D. (2005). On the evolution of invertebrate defensins. Trends in Genetics, 21 (6), 330-332.
Artículo
281 - Batista,C.V., Del Pozo,L., Zamudio,F.Z., Contreras,S., Becerril,B., Wanke,E., Possani,L.D. (2004). Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 803 (1), 55-66.
Artículo
Artículo
284 - Frenal,K., Xu,C.Q., Wolff,N., Wecker,K., Gurrola,G.B., Zhu,S.Y., Chi,C.W., Possani,L.D., Tytgat,J., Delepierre,M. (2004). Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K(+) channels. Proteins, 56 (2), 367-375.
Open Access Artículo
286 - Huys,I., Olamendi-Portugal,T., Garcia-Gomez,B.I., Vandenberghe,I., Van Beeumen,J., Dyason,K., Clynen,E., Zhu,S., van der Walt,J., Possani,L., Tytgat,J. (2004). A subfamily of acidic alpha -K+ toxins. Journal of Biological Chemistry, 279 (4), 2781-2789.
Artículo
287 - Montero-Solis,C., Gonzalez-Ceron,L., Rodriguez,M.H., Cirerol,B.E., Zamudio,F., Possanni,L.D., James,A.A., De La Cruz Hernandez-Hernandez,F. (2004). Identification and characterization of gp65, a salivary-gland-specific molecule expressed in the malaria vector Anopheles albimanus. Insect Molecular Biology, 13 (2), 155-164.
Artículo
Artículo
289 - Pascual,I., Gil-Parrado,S., Cisneros,M., Joseph-Bravo,P., Diaz,J., Possani,L.D., Charli,J.L., Chavez,M. (2004). Purification of a specific inhibitor of pyroglutamyl aminopeptidase II from the marine annelide Hermodice carunculata. In vivo effects in rodent brain. International Journal of Biochemistry and Cell Biology, 36 (1), 138-152.
Open Access Artículo
294 - Shalabi,A., Zamudio,F., Wu,X., Scaloni,A., Possani,L., Villereal,M.L. (2004). Tetrapandins, a new class of scorpion toxins that specifically inhibit store-operated calcium entry in HEK-293 cells. Journal of Biological Chemistry, 279 (2), 1040-1049.
Open Access Artículo
298 - Zhu,X., Zamudio,F.Z., Olbinski,B.A., Possani,L.D., Valdivia,H.H. (2004). Activation of skeletal ryanodine receptors by two novel scorpion toxins from buthotus judaicus. Journal of Biological Chemistry, 279 (25), 26588-26596.
Artículo
299 - Corona,M., Coronas,F.V., Merino,E., Becerril,B., Gutierrez,R., Rebolledo-Antunez,S., Garcia,D.E., Possani,L.D. (2003). A novel class of peptide found in scorpion venom with neurodepressant effects in peripheral and central nervous system of the rat. Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1649 (1), 58-67.
Artículo
304 - Guijarro,J.I., M'Barek,S., Gomez-Lagunas,F., Garnier,D., Rochat,H., Sabatier,J.M., Possani,L.D., Delepierre,M. (2003). Solution structure of Pi4, a short four-disulfide-bridged scorpion toxin specific of potassium channels. Protein Science, 12 (9), 1844-1854.
Artículo
305 - Gutierrez,M.C., Abarca,C., Possani,L.D. (2003). A toxic fraction from scolopendra venom increases the basal release of neurotransmitters in the ventral ganglia of crustaceans. Comparative Biochemistry and Physiology - C Toxicology and Pharmacology, 135 (2), 205-214.
Artículo
Carta
308 - Xu,C.Q., Zhu,S.Y., Chi,C.W., Tytgat,J., Possani,L.D., Rodriguez de la Vega,R.C. (2003). Turret and pore block of K+ channels: What is the difference? (multiple letters). Trends in Pharmacological Sciences, 24 (9), 446-449.
Artículo
309 - Angulo,Y., Olamendi-Portugal,T., Alape-Giron,A., Possani,L.D., Lomonte,B. (2002). Structural characterization and phylogenetic relationships of myotoxin II from Atropoides (Bothrops) nummifer snake venom, a Lys49 phospholipase A(2) homologue. International Journal of Biochemistry and Cell Biology, 34 (10), 1268-1278.
Artículo
Artículo
311 - Batista,C.V., Zamudio,F.Z., Lucas,S., Fox,J.W., Frau,A., Prestipino,G., Possani,L.D. (2002). Scorpion toxins from Tityus cambridgei that affect Na(+)-channels. Toxicon, 40 (5), 557-562.
Artículo
314 - Lecchi,M., Redaelli,E., Rosati,B., Gurrola,G., Florio,T., Crociani,O., Curia,G., Cassulini,R.R., Masi,A., Arcangeli,A., Olivotto,M., Schettini,G., Possani,L.D., Wanke,E. (2002). Isolation of a long-lasting eag-related gene-type K+ current in MMQ lactotrophs and its accommodating role during slow firing and prolactin release. Journal of Neuroscience, 22 (9), 3414-3425.
Artículo
315 - Olamendi-Portugal,T., Garcia,B.I., Lopez-Gonzalez,I., van der Walt,J., Dyason,K., Ulens,C., Tytgat,J., Felix,R., Darszon,A., Possani,L.D. (2002). Two new scorpion toxins that target voltage-gated Ca(2+) and Na(+) channels. Biochemical and Biophysical Research Communications, 299 (4), 562-568.
Open Access Artículo
317 - Pardo-Lopez,L., Zhang,M., Liu,J., Jiang,M., Possani,L.D., Tseng,G.N. (2002). Mapping the binding site of a human ether-a-go-go-related gene-specific peptide toxin (ErgTx) to the channel's outer vestibule. Journal of Biological Chemistry, 277 (19), 16403-16411.
Artículo
318 - Possani,L.D., Corona,M., Zurita,M., Rodriguez,M.H. (2002). From Noxiustoxin to Scorpine and Possible Transgenic Mosquitoes Resistant to Malaria. Archives of Medical Research, 33 (4), 398-404.
Artículo
Open Access Artículo
320 - Vacher,H., Alami,M., Crest,M., Possani,L.D., Bougis,P.E., Martin-Eauclaire,M.F. (2002). Expanding the scorpion toxin alpha-KTX 15 family with AmmTX3 from Androctonus mauretanicus. European Journal of Biochemistry, 269 (24), 6037-6041.
Artículo
322 - Frau,A., Pisciotta,M., Gurrola,G.B., Possani,L.D., Prestipino,G. (2001). Synthetic undecapeptide (NTX10-20) of noxiustoxin blocks completely the I(A) potassium currents of cerebellum granular cells. European Biophysics Journal, 29 (8), 569-573.
Artículo
324 - Goudet,C., Ferrer,T., Galan,L., Artiles,A., Batista,C.F., Possani,L.D., Alvarez,J., Aneiros,A., Tytgat,J. (2001). Characterization of two Bunodosoma granulifera toxins active on cardiac sodium channels. British Journal of Pharmacology, 134 (6), 1195-1206.
Artículo
325 - Nishigaki,T., Zamudio,F.Z., Possani,L.D., Darszon,A. (2001). Time-Resolved Sperm Responses to an Egg Peptide Measured by Stopped-Flow Fluorometry. Biochemical and Biophysical Research Communications, 284 (2), 531-535.
Artículo
326 - Peter,M.,Jr, Varga,Z., Hajdu,P., Gaspar,R., Damjanovich,S., Horjales,E., Possani,L.D., Panyi,G. (2001). Effects of toxins Pi2 and Pi3 on human T lymphocyte Kv1.3 channels: the role of Glu7 and Lys24. Journal of Membrane Biology, 179 (1), 13-25.
Artículo
327 - Rocchetti,M., Besana,A., Gurrola,G.B., Possani,L.D., Zaza,A. (2001). Rate dependency of delayed rectifier currents during the guinea-pig ventricular action potential. Journal of Physiology, 534 (Pt 3), 721-732.
Artículo
328 - Angulo,Y., Olamendi-Portugal,T., Possani,L.D., Lomonte,B. (2000). Isolation and characterization of myotoxin II from Atropoides (Bothrops) nummifer snake venom, a new Lys49 phospholipase A2 homologue. International Journal of Biochemistry and Cell Biology, 32 (1), 63-71.
Artículo
Artículo
332 - Peter,M.,Jr, Hajdu,P., Varga,Z., Damjanovich,S., Possani,L.D., Panyi,G., Gaspar,R. (2000). Blockage of human T lymphocyte Kv1.3 channels by Pi1, a novel class of scorpion toxin. Biochemical and Biophysical Research Communications, 278 (1), 34-37.
Artículo
333 - Pisciotta,M., Coronas,F.I., Bloch,C., Prestipino,G., Possani,L.D. (2000). Fast K(+) currents from cerebellum granular cells are completely blocked by a peptide purified from Androctonus australis Garzoni scorpion venom. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1468 (1-2), 203-212.
Carta
335 - Possani,L.D. (2000). Antivenom for scorpion sting. Lancet, 355 (9197), 67.
Artículo
337 - Altamirano,M.M., Garcia,C., Possani,L.D., Fersht,A.R. (1999). Oxidative refolding chromatography: folding of the scorpion toxin Cn5. Nature Biotechnology, 17 (2), 187-191.
Artículo
338 - Batista,C.V., da Silva,L.R., Sebben,A., Scaloni,A., Ferrara,L., Paiva,G.R., Olamendi-Portugal,T., Possani,L.D., Bloch,C. (1999). Antimicrobial peptides from the Brazilian frog Phyllomedusa distincta. Peptides, 20 (6), 679-686.
Artículo
342 - Delepierre,M., Prochnicka-Chalufour,A., Boisbouvier,J., Possani,L.D. (1999). Pi7, an orphan peptide from the scorpion Pandinus imperator: a 1H-NMR analysis using a nano-NMR Probe. Biochemistry, 38 (51), 16756-16765.
Artículo
Open Access Artículo
344 - Gurrola,G.B., Rosati,B., Rocchetti,M., Pimienta,G., Zaza,A., Arcangeli,A., Olivotto,M., Possani,L.D., Wanke,E. (1999). A toxin to nervous, cardiac, and endocrine ERG K+ channels isolated from Centruroides noxius scorpion venom. FASEB Journal, 13 (8), 953-962.
Artículo
345 - Ottolia,M., Babini,E., Gazzotti,P., Possani,L.D., Prestipino,G. (1999). Reconstitution of a voltage and calcium dependent potassium channel from rat cerebellum. Brain Research, 815 (2), 410-413.
Artículo
346 - Pintar,A., Possani,L.D., Delepierre,M. (1999). Solution structure of toxin 2 from centruroides noxius Hoffmann, a beta-scorpion neurotoxin acting on sodium channels. Journal of Molecular Biology, 287 (2), 359-367.
Revisión
347 - Possani,L.D., Selisko,B., Gurrola,G.B. (1999). Structure and function of scorpion toxins affecting K+-channels. Perspectives In Drug Discovery And Design, 16, 15-40.
Open Access Revisión
348 - Possani,L.D., Becerril,B., Delepierre,M., Tytgat,J. (1999). Scorpion toxins specific for Na+-channels. European Journal of Biochemistry, 264 (2), 287-300.
Artículo
350 - Tytgat,J., Chandy,K.G., Garcia,M.L., Gutman,G.A., Martin-Eauclaire,M.F., van der Walt,J.J., Possani,L.D. (1999). A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies. Trends in Pharmacological Sciences, 20 (11), 444-447.
Open Access Artículo
352 - Boisbouvier,J., Prochnicka-Chalufour,A., Nieto,A.R., Torres,J.A., Nanard,N., Rodriguez,M.H., Possani,L.D., Delepierre,M. (1998). Structural information on a cecropin-like synthetic peptide, Shiva-3 toxic to the sporogonic development of Plasmodium berghei. European Journal of Biochemistry, 257 (1), 263-273.
Artículo
353 - Delepierre,M., Prochnicka-Chalufour,A., Possani,L.D. (1998). 1H NMR structural analysis of novel potassium blocking toxins using a nano-NMR probe. Toxicon, 36 (11), 1599-1608.
Open Access Artículo
354 - Licea,A.F., Gutierrez,M.C., Esparza,J., Estrada-Parra,S., Estrada,G.I., Quesada-Pascual,F., Possani,L.D. (1998). Enhancement of the immunogenicity of Mycobacterium leprae peptides by means of polymerization. Asia-Pacific Journal Of Molecular Biology And Biotechnology, 6 (2), 89-95.
Artículo
357 - Peter,M.,Jr, Varga,Z., Panyi,G., Bene,L., Damjanovich,S., Pieri,C., Possani,L.D., Gaspar,R. (1998). Pandinus imperator scorpion venom blocks voltage-gated K+ channels in human lymphocytes. Biochemical and Biophysical Research Communications, 242 (3), 621-625.
Artículo
358 - Pisciotta,M., Ottolia,M., Possani,L.D., Prestipino,G. (1998). A novel toxin form the scorpion Androctonus australis blocks Shaker K+ channels expressed in Xenopus oocytes. Biochemical and Biophysical Research Communications, 242 (2), 287-291.
Artículo
360 - Possani,L.D., Zurita,M., Delepierre,M., Hernandez,F.H., Rodriguez,M.H. (1998). From noxiustoxin to Shiva-3, a peptide toxic to the sporogonic development of Plasmodium berghei. Toxicon, 36 (11), 1683-1692.
Artículo
362 - Tytgat,J., Debont,T., Rostoll,K., Muller,G.J., Verdonck,F., Daenens,P., van der Walt,J.J., Possani,L.D. (1998). Purification and partial characterization of a 'short' insectotoxin-like peptide from the venom of the scorpion Parabuthus schlechteri. FEBS Letters, 441 (3), 387-391.
Artículo
363 - Valdivia,H.H., Possani,L.D. (1998). Peptide toxins as probes of ryanodine receptor structure and function. Trends in Cardiovascular Medicine, 8 (3), 111-118.
Revisión
364 - Becerril,B., Marangoni,S., Possani,L.D. (1997). Toxins and genes isolated from scorpions of the genus Tityus. Toxicon, 35 (6), 821-835.
Artículo
365 - Ben Khalifa,R., Stankiewicz,M., Pelhate,M., Serrano-Hernandez,S.E., Possani,L.D., Hinkel,H., Mebs,D. (1997). Action of babycurus-toxin 1 from the east African scorpion Babycurus centrurimorphus on the isolated cockroach giant axon. Toxicon, 35 (7), 1069-1080.
Artículo
366 - Delepierre,M., Prochnicka-Chalufour,A., Possani,L.D. (1997). A novel potassium channel blocking toxin from the scorpion Pandinus imperator: A 1H NMR analysis using a nano-NMR probe. Biochemistry, 36 (9), 2649-2658.
Artículo
367 - Garcia,C., Becerril,B., Selisko,B., Delepierre,M., Possani,L.D. (1997). Isolation, characterization and comparison of a novel crustacean toxin with a mammalian toxin from the venom of the scorpion Centruroides noxius Hoffmann. Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, 116 (3), 315-322.
Artículo
370 - Zamudio,F.Z., Gurrola,G.B., Arevalo,C., Sreekumar,R., Walker,J.W., Valdivia,H.H., Possani,L.D. (1997). Primary structure and synthesis of Imperatoxin A (IpTx(a)), a peptide activator of Ca2+ release channels/ryanodine receptors. FEBS Letters, 405 (3), 385-389.
Open Access Artículo
371 - Zamudio,F.Z., Conde,R., Arevalo,C., Becerril,B., Martin,B.M., Valdivia,H.H., Possani,L.D. (1997). The mechanism of inhibition of ryanodine receptor channels by imperatoxin I, a heterodimeric protein from the scorpion Pandinus imperator. Journal of Biological Chemistry, 272 (18), 11886-11894.
Artículo
380 - Nobile,M., Noceti,F., Prestipino,G., Possani,L.D. (1996). Helothermine, a lizard venom toxin, inhibits calcium current in cerebellar granules. Experimental Brain Research, 110 (1), 15-20.
Artículo
383 - Vaca,L., Licea,A., Possani,L.D. (1996). Modulation of cell membrane potential in cultured vascular endothelium. American Journal of Physiology - Cell Physiology, 270 (3 Pt 1), C819-C824.
Artículo
385 - Becerril,B., Corona,M., Garcia,C., Bolivar,F., Possani,L.D. (1995). Cloning of genes encoding scorpion toxins: An interpretative review. Journal Of Toxicology-Toxin Reviews, 14 (3), 339-357.
Artículo
388 - Drakopoulou,E., Cotton,J., Virelizier,H., Bernardi,E., Schoofs,A.R., Partiseti,M., Choquet,D., Gurrola,G., Possani,L.D., Vita,C. (1995). Chemical synthesis, structural and functional characterisation of noxiustoxin, a powerful blocker of lymphocyte voltage-dependent K+ channels. Biochemical and Biophysical Research Communications, 213 (3), 901-907.
Artículo
389 - Gaspar,R., Bene,L., Damjanovich,S., Munoz-Garay,C., Calderon-Aranda,E.S., Possani,L.D. (1995). Beta-scorpion toxin 2 from Centruroides noxius blocks voltage-gated K+ channels in human lymphocytes. Biochemical and Biophysical Research Communications, 213 (2), 419-423.
Artículo
390 - Gurrola,G.B., Possani,L.D. (1995). Structural and functional features of noxiustoxin: a K+ channel blocker. Biochemistry and Molecular Biology International, 37 (3), 527-535.
Artículo
391 - Herion,P., Gurrola-Briones,G., Sanchez,M.D.R., Saavedra,R., Possani,L.D. (1995). Monoclonal antibodies against noxiustoxin. Hybridoma, 14 (3), 247-251.
Artículo
392 - Morrissette,J., Kratzschmar,J., Haendler,B., Elhayek,R., Mochca-Morales,J., Martin,B.M., Patel,J.R., Moss,R.L., Schleuning,W.D., Coronado,R., Possani,L.D. (1995). Primary Structure and Properties of Helothermine, A Peptide Toxin That Blocks Ryanodine Receptors. Biophysical Journal, 68 (6), 2280-2288.
Artículo
Open Access Artículo
394 - Noeske-Jungblut,C., Haendler,B., Donner,P., Alagon,A., Possani,L., Schleuning,W.D. (1995). Triabin, a highly potent exosite inhibitor of thrombin. Journal of Biological Chemistry, 270 (48), 28629-28634.
Note
395 - Possani,L.D. (1995). Monoclonal antibodies BNTX12, anti-noxiustoxin. Hybridoma, 14 (3), 301.
Note
396 - Possani,L.D. (1995). Monoclonal antibodies BNTX18, anti-noxiustoxin. Hybridoma, 14 (3), 304.
Note
397 - Possani,L.D. (1995). Monoclonal antibodies BNTX4, anti-noxiustoxin. Hybridoma, 14 (3), 300.
Note
398 - Possani,L.D. (1995). Monoclonal antibodies BNTX16, anti-noxiustoxin. Hybridoma, 14 (3), 303.
Note
399 - Possani,L.D. (1995). Monoclonal antibodies BNTX21, anti-noxiustoxin. Hybridoma, 14 (3), 305.
Note
400 - Possani,L.D. (1995). Monoclonal antibodies BNTX14, anti-noxiustoxin. Hybridoma, 14 (3), 302.
Artículo
401 - Rodriguez,M.C., Zamudio,F., Torres,J.A., Gonzalez-Ceron,L., Possani,L.D., Rodriguez,M.H. (1995). Effect of a cecropin-like synthetic peptide (Shiva-3) on the sporogonic development of Plasmodium berghei. Experimental Parasitology, 80 (4), 596-604.
Artículo
402 - Trequattrini,C., Zamudio,F.Z., Petris,A., Prestipino,G., Possani,L.D., Franciolini,F. (1995). Tityus bahiensis toxin IV-5b selectively affects Na channel inactivation in chick dorsal root ganglion neurons. Comparative Biochemistry and Physiology -- Part A: Physiology, 112 (1), 21-28.
Artículo
Artículo
405 - Dehesa-Davila,M., Possani,L.D. (1994). Scorpionism and serotherapy in Mexico. Toxicon, 32 (9), 1015-1018.
Artículo
406 - Fletcher,M.D., Possani,L.D., Fletcher,P.L. (1994). Morphological studies by light and electron microscopy of pancreatic acinar cells under the effect of Tityus serrulatus venom. Cell and Tissue Research, 278 (2), 255-264.
Artículo
408 - Gutierrez,M.C., ESTRADA,I.C.E., Estrada-Parra,S., Quesada-Pascual,F., Licea,A.F., Possani,L.D. (1994). The imunogenetic activity of synthetic peptides corresponding to M. Leprae protein sequences. Asia-Pacific Journal Of Molecular Biology And Biotechnology, 2, 143-150.
Artículo
Artículo
411 - Martin,B.M., Ramirez,A.N., Gurrola,G.B., Nobile,M., Prestipino,G., Possani,L.D. (1994). Novel K(+)-channel-blocking toxins from the venom of the scorpion Centruroides limpidus limpidus Karsch. Biochemical Journal, 304 (Pt 1), 51-56.
Artículo
412 - Nobile,M., Magnelli,V., Lagostena,L., Mochca-Morales,J., Possani,L.D., Prestipino,G. (1994). The toxin helothermine affects potassium currents in newborn rat cerebellar granule cells. Journal of Membrane Biology, 139 (1), 49-55.
Open Access Artículo
413 - Noeske-Jungblut,C., Kratzschmar,J., Haendler,B., Alagon,A., Possani,L., Verhallen,P., Donner,P., Schleuning,W.D. (1994). An inhibitor of collagen-induced platelet aggregation from the saliva of Triatoma pallidipennis. Journal of Biological Chemistry, 269 (7), 5050-5053.
Artículo
415 - Sacile,R., Ruggiero,C., Ballestrero,R., Possani,L.D., Prestipino,G., Rauch,G. (1994). Secondary structure of noxiustoxin and charybdotoxin from hydropathy power spectra. Biochemical and Biophysical Research Communications, 201 (1), 186-193.
Artículo
416 - Valdivia,H.H., Martin,B.M., Ramirez,A.N., Fletcher,P.L., Possani,L.D. (1994). Isolation and pharmacological characterization of four novel Na+ channel-blocking toxins from the scorpion Centruroides noxius Hoffmann. Journal of Biochemistry, 116 (6), 1383-1391.
Artículo
Artículo
420 - Vaca,L., Gurrola,G.B., Possani,L.D., Kunze,D.L. (1993). Blockade of a KCa channel with synthetic peptides from noxiustoxin: a K+ channel blocker. Journal of Membrane Biology, 134 (2), 123-129.
Open Access Artículo
422 - Estrada,I.C., Gutierrez,M.C., Esparza,J., Quesada-Pascual,F., Estrada-Parra,S., Possani,L.D. (1992). Use of synthetic peptides corresponding to sequences of Mycobacterium leprae proteins to study delayed-type hypersensitivity response in sensitized guinea pigs. International Journal of Leprosy, 60 (1), 18-27.
Artículo
423 - Fletcher,P.L., Fletcher,M.D., Possani,L.D. (1992). Characteristics of pancreatic exocrine secretion produced by venom from the Brazilian scorpion, Tityus serrulatus. European Journal of Cell Biology, 58 (2), 259-270.
Note
424 - Harvey,A.L., Marshall,D.L., Possani,L.D. (1992). Dendrotoxin-like effects of noxiustoxin. Toxicon, 30 (11), 1497-1500.
Open Access Artículo
425 - Possani,L.D., Fletcher,P.L., Fletcher,M.D., Rode,G.S., Mochca-Morales,J., Lucas,S., Coronas,F.V., Alagon,A.C., Martin,B.M. (1992). Structural and functional characteristics of toxins purified from the venom of the Brazilian scorpion Tityus serrulatus Lutz and Mello. Memorias do Instituto Butantan, 54 (2), 35-52.
Artículo
426 - Possani,L.D., Mochca-Morales,J., Amezcua,J., Martin,B.M., Prestipino,G., Nobile,M. (1992). Anionic currents of chick sensory neurons are affected by a phospholipase A2 purified from the venom of the taipan snake. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1134 (3), 210-216.
Artículo
427 - Possani,L.D., Martin,B.M., Yatani,A., Mochca-Morales,J., Zamudio,F.Z., Gurrola,G.B., Brown,A.M. (1992). Isolation and physiological characterization of taicatoxin, a complex toxin with specific effects on calcium channels. Toxicon, 30 (11), 1343-1364.
Artículo
428 - Valdivia,H.H., Martin,B.M., Escobar,L., Possani,L.D. (1992). Noxiustoxin and leiurutoxin III, two homologous peptide toxins with binding properties to synaptosomal membrane K+ channels. Biochemistry International, 27 (6), 953-962.
Open Access Artículo
430 - Possani,L.D., Martin,B.M., Fletcher,M.D., Fletcher,P.L. (1991). Discharge effect on pancreatic exocrine secretion produced by toxins purified from Tityus serrulatus scorpion venom. Journal of Biological Chemistry, 266 (5), 3178-3185.
Artículo
431 - Colden-Stanfield,M., Schilling,W.P., Possani,L.D., Kunze,D.L. (1990). Bradykinin-induced potassium current in cultured bovine aortic endothelial cells. Journal of Membrane Biology, 116 (3), 227-238. *
Artículo
436 - Kirsch,G.E., Skattebol,A., Possani,L.D., Brown,A.M. (1989). Modification of Na channel gating by an alpha scorpion toxin from Tityus serrulatus. Journal of General Physiology, 93 (1), 67-83.
Artículo
437 - Prestipino,G., Valdivia,H.H., Lievano,A., Darszon,A., Ramirez,A.N., Possani,L.D. (1989). Purification and reconstitution of potassium channel proteins from squid axon membranes. FEBS Letters, 250 (2), 570-574.
Artículo
438 - Alagon,A.C., Guzman,H.S., Martin,B.M., Ramirez,A.N., Carbone,E., Possani,L.D. (1988). Isolation and characterization of two toxins from the Mexican scorpion Centruroides limpidus limpidus Karsch. Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, 89 (1), 153-161.
Artículo
439 - Martin,B.M., Carbone,E., Yatani,A., Brown,A.M., Ramirez,A.N., Gurrola,G.B., Possani,L.D. (1988). Amino acid sequence and physiological characterization of toxins from the venom of the scorpion Centruroides limpidus tecomanus Hoffmann. Toxicon, 26 (9), 785-794.
Artículo
Artículo
441 - Valdivia,H.H., Smith,J.S., Martin,B.M., Coronado,R., Possani,L.D. (1988). Charybdotoxin and noxiustoxin, two homologous peptide inhibitors of the K+ (Ca2+) channel. FEBS Letters, 226 (2), 280-284.
Artículo
442 - Yatani,A., Kirsch,G.E., Possani,L.D., Brown,A.M. (1988). Effects of New World scorpion toxins on single-channel and whole cell cardiac sodium currents. American Journal of Physiology Heart and Circulatory Physiology, 254 (3 Pt 2), H443-H451.
Artículo
443 - Brown,A.M., Yatani,A., Lacerda,A.E., Gurrola,G.B., Possani,L.D. (1987). Neurotoxins that act selectively on voltage-dependent cardiac calcium channels. Circulation Research, 61 (4 Pt 2), I6-I9.
Artículo
444 - Carbone,E., Prestipino,G., Spadavecchia,L., Franciolini,F., Possani,L.D. (1987). Blocking of the squid axon K+ channel by noxiustoxin: a toxin from the venom of the scorpion Centruroides noxius. Pflugers Archiv European Journal of Physiology, 408 (5), 423-431.
Artículo
446 - Alagon,A., Possani,L.D., Smart,J., Schleuning,W.D. (1986). Helodermatine, a kallikrein-like, hypotensive enzyme from the venom of Heloderma horridum horridum (Mexican beaded lizard). Journal of Experimental Medicine, 164 (6), 1835-1845.
Artículo
447 - Rodriguez,A., Tablero,M., Barragan,B., Lara,P., Rangel,M., Arreguin,B., Possani,L., Soriano-Garcia,M. (1986). Crystallization of Hevein - A Protein from Latex of Hevea-Brasiliensis (Rubber Tree). Journal of Crystal Growth, 76 (3), 710-714. *
Artículo
450 - Possani,L.D., Martin,B.M., Svendsen,I., Rode,G.S., Erickson,B.W. (1985). Scorpion toxins from Centruroides noxius and Tityus serrulatus. Primary structures and sequence comparison by metric analysis. Biochemical Journal, 229 (3), 739-750. *
Artículo
451 - Carbone,E., Prestipino,G., Franciolini,F., Dent,M.A., Possani,L.D. (1984). Selective modification of the squid axon Na currents by Centruroides noxius toxin II-10. Journal de Physiologie, 79 (4), 179-184. *
Artículo
453 - Carbone,E., Wanke,E., Prestipino,G., Possani,L.D., Maelicke,A. (1982). Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin. Nature, 296 (5852), 90-91. *
Artículo
454 - Carbone,E., Wanke,E., Prestipino,G., Possani,L.D., Maelicke,A. (1982). Selective Action of Purified Scorpion Neurotoxins on the Ionic Currents of the Squid Giant-Axon. Hoppe-Seylers Zeitschrift fur Physiologische Chemie, 363 (2), 1299-1300. *
Open Access Artículo
455 - Possani,L.D., Martin,B.M., Svendsen,I.B. (1982). The Primary Structure of Noxiustoxin - A K+-Channel Blocking Peptide, Purified from the Venom of the Scorpion Centruroides-Noxius Hoffmann. Carlsberg Research Communications, 47 (5), 285-289. *
Artículo
456 - Trejo,A.C., Possani,L.D. (1982). Electron microscopic evidence for scorpion toxin binding to synapses of rat brain cortex. Neuroscience Letters, 32 (2), 103-108. *
Artículo
457 - Perez de la Mora,M., Possani,L.D., Tapia,R., Teran,L., Palacios,R., Fuxe,K., Hokfelt,T., Ljungdahl,A. (1981). Demonstration of central gamma-aminobutyrate-containing nerve terminals by means of antibodies against glutamate decarboxylase. Neuroscience, 6 (5), 875-895. *
Artículo
458 - Possani,L., Steinmetz,W.E., Dent,M.A., Alagon,A.C., Wuthrich,K. (1981). Preliminary spectroscopic characterization of six toxins from Latin American scorpions. Biochimica et Biophysica Acta (BBA) - Protein Structure, 669 (2), 183-192. *
Open Access Artículo
459 - Possani,L.D., Dent,M.A.R., Martin,B.M., Maelicke,A., Svendsen,I. (1981). The Amino Terminal Sequence of Several Toxins from the Venom of the Mexican Scorpion Centruroides Noxius Hoffmann. Carlsberg Research Communications, 46 (4), 207-214. *
Open Access Artículo
460 - Possani,L.D., Martin,B.M., Mochcamorales,J., Svendsen,I. (1981). Purification and Chemical Characterization of the Major Toxins from the Venom of the Brazilian Scorpion Tityus Serrulatus Lutz and Mello. Carlsberg Research Communications, 46 (4), 195-205. *
Note
461 - Possani,L.D., Fernandez de Castro,J., Julia,J.Z. (1981). Detoxification with glutaraldehyde of purified scorpion (Centruroides noxius Hoffmann) venom. Toxicon, 19 (2), 323-329. *
Artículo
462 - Alagon,A.C., Molinar,R.R., Possani,L.D., Fletcher,P.L., Cronan,J.E., Julia,J.Z. (1980). Venom from the snake Bothrops asper Garman. Purification and characterization of three phospholipases A2. Biochemical Journal, 185 (3), 695-704. *
Artículo
Artículo
467 - Sosa,B.P., Alagon,A.C., Possani,L.D., Julia,J.Z. (1979). Comparison of phospholipase activity with direct and indirect lytic effects of animal venoms upon human red cells. Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 64 (2), 231-234. *
Note
468 - Bayon,A., Possani,L.D., Rode,G., Tapia,R. (1978). Kinetics of brain glutamate decarboxylase. Dead-end and product inhibition studies. Journal of Neurochemistry, 30 (6), 1629-1631. *
Artículo
469 - Hokfelt,T., Elde,R., Fuxe,K., Johansson,O., Ljungdahl,A., Goldstein,M., Luft,R., Efendic,S., Nilsson,G., Terenius,L., Ganten,D., Jeffcoate,S.L., Rehfeld,J., Said,S., Perez de la Mora,M., Possani,L., Tapia,R., Teran,L., Palacios,R. (1978). Aminergic and peptidergic pathways in the nervous system with special reference to the hypothalamus. Research publications - Association for Research in Nervous and Mental Disease, 56, 69-135. *
Artículo
470 - Possani,L.D., Ramirez,G.A., Fletcher,P.L., Gurrola,M.A. (1978). Isolation of two mammalian toxins from the venom of the Mexican scorpion Centruroides elegans (Thorell). FEBS Letters, 91 (2), 261-264. *
Artículo
Artículo
472 - Bayon,A., Possani,L.D., Tapia,R. (1977). Kinetics of brain glutamate decarboxylase. Inhibition studies with N-(5'-phosphopyridoxyl) amino acids. Journal of Neurochemistry, 29 (3), 513-517. *
Artículo
473 - Possani,L.D., Bayon,A., Tapia,R. (1977). Synthesis of affinity chromatography resins for the purification of brain glutamate decarboxylase. Neurochemical Research, 2 (1), 51-57. *
Artículo
474 - Possani,L.D., Alagon,A.C., Fletcher,P.L., Erickson,B.W. (1977). Purification and properties of mammalian toxins from the venom of Brazilian Scorpion Tityus serrulatus Lutz and Mello. Archives of Biochemistry and Biophysics, 180 (2), 394-403. *
Open Access Artículo
475 - Klett,R.P., Fulpius,B.W., Cooper,D., Smith,M., Reich,E., Possani,L.D. (1973). The acetylcholine receptor. I. Purification and characterization of a macromolecule isolated from Electrophorus electricus. Journal of Biological Chemistry, 248 (19), 6841-6853. *
Artículo
476 - Possani,L.D. (1973). GABA effects and GABA receptors in neuromuscular junctions of crustaceans: analysis of some stereochemical models. Revista brasileira de pesquisas medicas e biologicas, 6 (1), 31-42. *
Artículo
477 - Tondo,C.V., Possani,L.D. (1972). Study of the bimodal frequency distribution of the relative concentration of hemoglobin S in heterozygous carriers. Revista brasileira de pesquisas medicas e biologicas, 5 (1-2), 47-56. *
Artículo
478 - Possani,L.D., Banerjee,R., Balny,C., Douzou,P. (1970). Oxidation of haemoglobin by oxygen in light: possible role of singlet oxygen. Nature, 226 (248), 861-862. *
Internacional
479 - Abdel-Rahman,M.A., Quintero-Hernandez,V., Possani,L.D. (2014). Scorpion Venom Gland Transcriptomics and Proteomics: An Overview. Venom Genomics and Proteomics. 105-124.
Internacional
480 - Rodriguez de la Vega,R.C., Corzo,G., Possani,L.D. (2014). Scorpion Venoms as a Platform for Drug Development. Venoms to Drugs: Venom as a Source for the Development of Human Therapeutics. 204-220, Cambridge: Royal Society of Chemistry.
Internacional
Internacional
482 - Petricevich,V.L., Barbosa-Navarro,L., Possani,L.D. (2013). Therapeutic use of scorpion venom. Molecular aspects of inflammation. 209-231, Kerala: Research Signpost.
Internacional
483 - Rodriguez-de-la-Vega,R., Vidal,N., Possani,L.D. (2013). Scorpion Peptides. Handbook of Biologically Active Peptides, second edition . 423-429.
Internacional
484 - Possani,L.D., Gurrola,G.B., Schwartz,E., Restano,R. (2011). Bioquimica y biologia molecular de los venenos de escorpiones de importancia medica en el continente americano. Emergencias por Animales Ponzonosos en las Americas . 147-180, Mexico.
Internacional
485 - Valdez-Cruz,N.A., Conde,R., Zamudio,F., Possani,L.D. (2011). Anticoagulants from scorpion venoms. Toxins and Hemostasis: From Bench to Bedside . 255-266.
Internacional
486 - Rodriguez-de-la-Vega,R., Barraza,R., Restano,R., Possani,L.D. (2009). Toxins active on Herg channel: structure and function. Animal toxins: State of the Art. Perspectives in Health and Biotechnology . 193-204, Belo Horizonte: EditoraUFMG.
Nacional
487 - Possani-Postay,L.D. (2008). El estudio de los componentes del veneno de alacranes en el contexto de la biología molecular, la farmacología y la medicina. Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 16. 179-187, Mexico, D.F..
Internacional
488 - Delepierre,M., Possani,L.D. (2006). Pharmaceutical Applications of Ion Channel Blockers: Use of NMR to Determine the Structure of Scorpion Toxins. Modern Magnetic Resonance. 1325-1330, 2, Dordrecht: Springer.
Internacional
489 - Possani,L.D., Rodriguez de la Vega,R.C. (2006). Scorpion venom peptides. Handbook of Biologically Active Peptides. 339-354, San Diego.
Nacional
490 - Alagon,A., Possani,L.D. (2003). Desarrollo de nuevos f rmacos a partir de la fauna tropical. Fronteras de la Biología en los Inicios del Siglo XXI, Módulo VII . 123-160, Mexico,D.F..
Internacional
491 - Possani,L.D., Merino,E., Corona,M., Becerril,B. (2002). Scorpion genes and peptides specific for potassium channels: Structure, function and evolution. Perspectives in Molecular Toxinology. 201-214.
Internacional
492 - Possani,L.D., Becerril,B., Tytgat,J., Delepierre,M. (2001). High Affinity Scorpion Toxins for Studying Potassium and Sodium Channels. Ion Channel Localization Methods and Protocols: Methods and Protocols. 145-165.
Internacional
493 - Calderon-Aranda,E.S., Dehesa-Davila,M., Chavez-Haro,A., Possani,L.D. (1996). Scorpion stings and their treatment in Mexico. Envenomings and their treatment. 311-320, Lyon.
Internacional
494 - Dehesa-Davila,M., Alagon,A.C., Possani,L.D. (1995). Clinical toxicology of scorpion stings. Handbook of clinical toxicology of animal venoms and poisons. 221-238, New York.
Memoria in extenso
495 - Gutierrez,M.C., Estrada,G.I., Estrada-Parra,S., Gurrola,G.B., Possani,L.D. (1991). Synthetic peptides as skin test reagents in leprosy. Proceedings Leprosy Research in Latin America. 7 p, Caracas.
Memoria in extenso
496 - Possani,L.D., Gurrola,G.B., Portugal,T.O., Zamudio,F.Z., Vaca,L.D., Calderon,S.A., Kirsch,G.E. (1991). Scorpion toxins: a model for peptide synthesis of new drugs. Proceedings First Brazilian Congress on Proteins. 352-367, Brasil.
Nacional
497 - Gurrola,G.B., Molina-Rode,R., Zentella,A.D., Possani,L.D. (1984). Sintesis de peptidos y su posible utilizacion como vacuna contra toxinas de alacran. Avances en el mecanismo de accion de farmacos. 35-50.
Internacional
498 - Possani,L.D. (1984). Structure of scorpion toxins. Handbook of natural toxins. 513-550, New York. *
Memoria in extenso
499 - Perez de la Mora,M., Fuxe,K., Hokfelt,T., Anderson,K., Possani,L., Tapia,R. (1981). Gabaergic synapses: distribution and interaction with other Neurotransmitter systems in the brain. Regulatory Mechanisms of Synaptic Transmission. 71-101, Boston,MA. *
Internacional
500 - Fuxe,K., Andersson,K., Schwarcz,R., Agnati,L.F., Perez de la Mora,M., Hokfelt,T., Goldstein,M., Ferland,L., Possani,L., Tapia,L. (1979). Studies on different types of dopamine nerve terminals in the forebrain adn their possible interactions with neurons. Advances in neurology. Advances in neurology, 199-216, New York. *
Memoria in extenso
501 - Perez de la Mora,M., Fuxe,K., Andersson,K., Hokfelt,T., Ljungdahl,A., Possani,L., Tapia,R. (1979). STUDIES ON GABA-MONOAMINE AND GABA-ENDORPHIN INTERACTIONS. Catecholamines: Basic and Clinical Frontiers Proceedings of the Fourth International Catecholamine Symposium, Pacific Grove, California, September 17-22, 1978. 1032-1034. *
Internacional
502 - Alagon,A.C., Possani,L.D., Erickson,B.W. (1978). ISOLATION AND CHARACTERIZATION OF SEVERAL PROTEINS FROM TITYUS SERRULATUS SCORPION VENOM. Toxins Animal, Plant and Microbial. 609-618. *
Internacional
503 - Fuxe,K., Hokfelt,T., Agnati,L.F., Johansson,O., Goldstein,M., Perez de la Mora,M., Possani,L., Tapia,R., Teran,L., Palacios,R. (1978). Mapping out central catecholamine synthesizing neurons: immunohistochemical studies on catecholamine-synthesizing enzymes. Psychopharmacology: a Generation of Progress. 67-94, New York. *
Internacional
504 - Gopalakrishnakone, P., Possani, L. D., Schwartz, E., Rodriguez-de-la-Vega, R. (2014). Scorpion Venoms. Toxinology, Dordrecht: Springer.
Divulgación
505 - Possani,L.D. (2005). El alacrán y su piquete. Mexico: Gobierno del Distrito Federal.
Nacional
506 - Alagon,A., Carillo,C., Chavez-Haro,A., De la Mora-Zerpa,C., Larralde,C., Lamas,N, Martin,E, Osnaya-Romero,N., Perez,Y, Possani,L.D., Romero-Zamora,L. (2003). Práctica Médica Efectiva- Alacranismo (T63.2, X22). Mexico.
Open Access nacional divulgacion
507 - Possani Postay,L.D. (2023). Un interés dedicado al conocimiento y las tecnologías para la salud a partir de venenos de alacranes. Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM, 9 (32).
Open Access Divulgación
508 - Carcamo-Noriega,E.N., Possani-Postay,L.D. (2019). Veneno rojo: un potencial antibiotico contra la tuberculosis obtenido del veneno del alacran. Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM, 18, 20-23.
Editorial Material
510 - Garcia,M.L., Possani,L.D. (2007). Gating modifier peptides of ion channels. Toxicon, 49 (2), 123.
Editorial Material
Editorial Material
512 - Possani,L.D. (2003). The past, present, and future of biotechnology in Mexico. Nature Biotechnology, 21 (5), 582-583.
Editorial Material
Nacional
514 - Possani,L.D. (2000). Alacranismo en Mexico. La salud en Durango, 1, 5-6.
Nacional
515 - Domingos Possani,L. (1983). The toxins of scorpion venom: structure and function. Boletin de estudios medicos y biologicos, 32 (7-8 Suppl 1), 285-297.
516 - Possani Postay, Lourival, D. (2024). Caracterización del veneno de alacrán Hoffmannihadrurus aztecus. Dirección de Ingenieria en Biotecnología y Tecnologia Ambiental, Licenciatura, Universidad Politécnica del Estado de Morelos. *
Open Access Artículo
522 - Gonzalez-Santillan,E., Valdez-Velazquez,L.L., Delgado-Hernandez,O., Cid-Uribe,J.I., Romero-Gutierrez,M.T., Possani,L.D.. A multigene approach to identify the scorpion species (Arachnida: Scorpiones) of Colima, Mexico, with comments on their venom diversity. Revista Mexicana de Biodiversidad, 95, e955373.
Open Access Artículo
Open Access Articulo
525 - Possani Postay, Lourival, D.. Caracterización del veneno de alacrán Hoffmannihadrurus aztecus. Dirección de Ingenieria en Biotecnología y Tecnologia Ambiental, Licenciatura, Universidad Politécnica del Estado de Morelos. *
Open Access Artículo
526 - Garcia-Villalvazo,P.E, Jimenez-Vargas,J.M, Lino-Lopez,G.J, Meneses,E.P, Bermudez-Guzman,M.J, Barajas-Saucedo,C.E, Delgado-Enciso,I., Possani,L.D, Valdez-Velazquez,L.L. Unveiling the Protein Components of the Secretory-Venom Gland and Venom of the Scorpion Centruroides possanii (Buthidae) through Omic Technologies. Toxins (Basel), 15 (8), 498.
Artículo
Artículo
528 - Ibarra-Vega,R., Jimenez-Vargas,J.M., Pineda-Contreras,A., Martinez-Martinez,F.J., Barajas-Saucedo,C.E., Garcia-Ortega,H., Magana-Vergara,N.E., Possani,L.D., Corzo,G., Gaitan-Hinojosa,M.A., Vazquez-Vuelvas,O.F., Zamudio,F., Valdez-Velazquez,L.L.. Indolealkylamines in the venom of the scorpion Thorellius intrepidus. Toxicon, 233, 107232.
Artículo
529 - Lopez-Giraldo,E., Carrillo,E., Titaux-Delgado,G., Cano-Sanchez,P., Colorado,A., Possani,L.D., Rio-Portilla,F.D.. Structural and functional studies of scorpine: A channel blocker and cytolytic peptide. Toxicon, 222, 106985 .
Open Access Artículo
Artículo
Artículo
532 - Salazar,M.H., Ortiz,M.H., Encarnacion,S., Zamudio,F., Possani,L.D., Cleghorn,J., Moran,M., Acosta,H., Corzo,G.. A proteomic overview of the major venom components from Tityus championi from Panama. Toxicon, 227, 107082.
Open Access Artículo
Artículo
Open Access nacional divulgacion
535 - Possani Postay,L.D.. Un interés dedicado al conocimiento y las tecnologías para la salud a partir de venenos de alacranes. Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM, 9 (32).
Artículo
536 - Bermudez-Guzman,M.J., Jimenez-Vargas,J.M., Possani,L.D., Zamudio,F., Ororzco-Gutierrez,G., Oceguera-Contreras,E., Enriquez-Vara,J.N, Vazquez-Vuelvas,O.F., Garcia-Villalvazo,P.E., Valdez-Velazquez,L.L.. Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus. Toxicon, 206, 90-102.
Open Access Artículo
537 - Csoti,A., Najera-Meza,R.C., Bogar,F., Tajti,G., Szanto,T.G., Varga,Z., Gurrola,G.B., Toth,G.K., Possani,L.D., Panyi,G.. sVmKTx, a transcriptome analysis-based synthetic peptide analogue of Vm24, inhibits Kv1.3 channels of human T cells with improved selectivity. Biochemical Pharmacology, 199, 115023.
Open Access Artículo
538 - Delgado-Prudencio,G., Cid-Uribe,J.I., Morales,J.A., Possani,L.D., Ortiz,E., Romero-Gutierrez,T.. The Enzymatic Core of Scorpion Venoms. Toxins, 14 (4), 248.
Open Access Artículo
539 - Espinoza-Duarte,M.R., Ortega-Ochoa,C., Baca-Ramirez,A., Possani,L.D., Espino-Solis,G.P.. Flow cytometry analysis of CD11c-positive peripheral blood mononuclear cells in horses. Veterinary Immunology and Immunopathology, 253 (November), 110504.
Artículo
540 - Naseem,M.U., Carcamo-Noriega,E., Borrego,J., Szanto,T.G., Zamudio,F.Z., Delgado-Prudencio,G., Possani,L.D., Panyi,G.. Cm28, a scorpion toxin having a unique primary structure, inhibits KV1.2 and KV1.3 with high affinity. Journal of General Physiology, 154 (8), e202213146.
Open Access Artículo
Open Access Artículo
Open Access Artículo
Artículo
544 - Alamilla,J., Jimenez-Vargas,J.M., Galvan-Hernandez,A.R., Reyes-Mendez,M.E., Bermudez-Guzman,M.J., Restano-Cassulini,R., Olamendi-Portugal,T., Zamudio,F.Z., Possani,L.D., Valdez-Velazquez,L.L.. Toxin Ct1a, from venom of Centruroides tecomanus, modifies the spontaneous firing frequency of neurons in the suprachiasmatic nucleus. Toxicon, 197, 114-125.
Open Access Artículo
Artículo
Artículo
547 - Lopes,K.S., Torres Quintanilha,M.V., Barros de Souza,A.C., Zamudio-Zuniga,F., Possani,L.D., Mortari,M.R.. Antiseizure potential of peptides from the venom of social wasp Chartergellus communis against chemically-induced seizures. Toxicon, 194, 23.
Open Access Artículo
Open Access Artículo
549 - Rodriguez-Ravelo,R., Ruiz-Urquiola,A., Possani-Postay,L.D., Morris-Quevedo,H.J., Rodriguez-Ravelo,M., Espinosa-Lopez,G.. Variation of cytochrome oxidase-I gene and venom proteins of Rhopalurus junceus populations in the Moanicum sector: Pharmacological implications. Journal of Pharmacy and Pharmacognosy Research, 9 (1), 1-12.
Artículo
550 - Vargas-Jaimes,L., Rodriguez,M.C., Argotte-Ramos,R., Juarez-Gonzalez,V.R., Pastor,N., Cesa-Luna,C., Possani,L.D., Quintero-Hernandez,V.. Recombinant C-Terminal Domains from Scorpine-like Peptides Inhibit the Plasmodium berghei Ookinete Development In Vitro. International Journal of Peptide Research and Therapeutics, 27, 817-829.
Artículo
Revisión
552 - Cid-Uribe,J.I., Veytia-Bucheli,J.I., Romero-Gutierrez,T., Ortiz,E., Possani,L.D.. Scorpion venomics: a 2019 overview. Expert Review of Proteomics, 17 (1), 67-83.
Artículo
553 - Cota-Arce,J.M., Zazueta-Favela,D., Diaz-Castillo,F., Jimenez,S., Bernaldez-Sarabia,J., Caram-Salas,N.L., Dan,K.W.L., Escobedo,G., Licea-Navarro,A.F., Possani,L.D., De Leon-Nava,M.A.. Venom components of the scorpion Centruroides limpidus modulate cytokine expression by T helper lymphocytes: Identification of ion channel-related toxins by mass spectrometry. International Immunopharmacology, 84, 106505.
Artículo
554 - El-Bitar, A. M. H., Sarhan, M., Abdel-Rahman, M. A., Quintero-Hernandez, V., Aoki-Utsubo, C., Moustafa, M. A., Possani, L. D., Hotta, H.. Smp76, a Scorpine-Like Peptide Isolated from the Venom of the Scorpion Scorpio maurus palmatus, with a Potent Antiviral Activity Against Hepatitis C Virus and Dengue Virus. International Journal of Peptide Research and Therapeutics, 26, 811-821.
Artículo
Artículo
Artículo
Artículo
558 - Luna-Ramirez,K., Csoti,A., McArthur,J.R., Chin,Y.K.Y., Anangi,R., Najera,R.D.C., Possani,L.D., King,G.F., Panyi,G., Yu,H., Adams,D.J., Finol-Urdaneta,R.K.. Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom. Biochemical Pharmacology, 174, 113782.
Artículo
559 - Mourao,C.B.F., Brand,G.D., Fernandes,J.P.C., Prates,M.V., Bloch,C., Barbosa,J.A.R.G., Freitas,S.M., Restano-Cassulini,R., Possani,L.D., Schwartz,E.F.. Head-to-Tail Cyclization after Interaction with Trypsin: A Scorpion Venom Peptide that Resembles Plant Cyclotides. Journal of Medicinal Chemistry, 63 (17), 9500?951.
Open Access Artículo
Artículo
Artículo
Open Access Artículo
563 - Bernaldez-Sarabia,J., Figueroa-Montiel,A., Duenas,S., Cervantes-Luevano,K., Beltran,J.A., Ortiz,E., Jimenez,S., Possani,L.D., Paniagua-Solis,J.F., Gonzalez-Canudas,J., Licea-Navarro,A.. The Diversified O-Superfamily in Californiconus californicus Presents a Conotoxin with Antimycobacterial Activity. Toxins (Basel), 11 (2), E128.
Artículo
564 - Carcamo-Noriega,E.N., Sathyamoorthi,S., Banerjee,S., Gnanamani,E., Mendoza-Trujillo,Monserrat, Mata-Espinosa,D., Hernandez-Pando,R., Veytia-Bucheli,J.I., Possani,L.D., Zare,R.N.. 1,4-Benzoquinone antimicrobial agents against Staphylococcus aureus and Mycobacterium tuberculosis derived from scorpion venom. Proceedings of the National Academy of Sciences, 116 (26), 201812334, 12642-12647.
Artículo
Open Access Artículo
Open Access Artículo
Artículo
Artículo
Open Access Artículo
Open Access Artículo
Artículo
Open Access Artículo
573 - Santibanez-Lopez,C.E., Graham,M.R., Sharma,P.P., Ortiz,E., Possani,L.D.. Hadrurid Scorpion Toxins: Evolutionary Conservation and Selective Pressures. Toxins (Basel), 11 (11), E637, E637.
Open Access Divulgación
574 - Carcamo-Noriega,E.N., Possani-Postay,L.D.. Veneno rojo: un potencial antibiotico contra la tuberculosis obtenido del veneno del alacran. Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM, 18, 20-23.
Open Access Artículo
Artículo
576 - Banerjee, S., Gnanamani, E., Lynch, S.R., Zamudio-Zuniga, F., Jimenez-Vargas, J.M., Possani, L.D., Zare, R.N.. An Alkaloid from Scorpion Venom: Chemical Structure and Synthesis. Journal of Natural Products, 81 (8), 1899-1904.
Artículo
Artículo
Artículo
Revisión
Artículo
Revisión
Open Access Artículo
Artículo
584 - Salazar, M.H., Arenas, I., Corrales-Garcia, L.L., Miranda, R., Velez, S., Sanchez, J., Mendoza, K., Cleghorn, J., Zamudio, F.Z., Castillo, A., Possani, L.D., Corzo, G., Acosta, H.. Venoms of Centruroides and Tityus species from Panama and their main toxic fractions. Toxicon, 141, 79-87.
Open Access Artículo
Open Access Artículo
Artículo
Artículo
Artículo
Artículo
Revisión
591 - Jimenez-Vargas, J.M., Possani, L.D., Luna-Ramirez, K.. Arthropod toxins acting on neuronal potassium channels. Neuropharmacology, 127, 139-160.
Artículo
592 - Lopes, K.S., Campos, G.A.A., Camargo, L.C., de Souza, A.C.B., Ibituruna, B.V., Magalhaes, A.C.M., da Rocha, L.F., Garcia, A.B., Rodrigues, M.C., Ribeiro, D.M., Costa, M.C., Lopez, M.H.M., Nolli, L.M., Zamudio-Zuniga, F., Possani, L.D., Schwartz, E.F., Mortari, M.R.. Characterization of two peptides isolated from the venom of social wasp Chartergellus communis (Hymenoptera: Vespidae): Influence of multiple alanine residues and C-terminal amidation on biological effects. Peptides, 95, 84-93.
Artículo
Artículo
Open Access Artículo
595 - Restano-Cassulini, R., Garcia, W., Paniagua-Solis, J.F., Possani, L.D.. Antivenom Evaluation by Electrophysiological Analysis. Toxins (Basel), 9 (3), 74.
Artículo
Open Access Artículo
Artículo
Artículo
599 - Vargas-Jaimes, L., Xiao, L., Zhang, J., Possani, L.D., Valdivia, H.H., Quintero-Hernandez, V.. Recombinant expression of Intrepicalcin from the scorpion Vaejovis intrepidus and its effect on skeletal ryanodine receptors. Biochimica et Biophysica Acta (BBA) - General Subjects, 1861 (4), 936-946.
Open Access Artículo
600 - Figueroa-Montiel,A., Ramos,M.A., Mares,R.E., Duenas,S., Pimienta,G., Ortiz,E., Possani,L.D., Licea-Navarro,A.F.. In Silico Identification of Protein Disulfide Isomerase Gene Families in the De Novo Assembled Transcriptomes of Four Different Species of the Genus Conus. PLoS ONE, 11 (2), e0148390.
Revisión
601 - Luna-Martinez,K., Jimenez-Vargas,J.M., Possani,L.D.. Scorpine-Like Peptides. Single Cell Biology, 5 (138).
Artículo
Artículo
603 - Osnaya-Romero N., Acosta-Saavedra,L.C., Goytia-Acevedo,R., Lares-Asseff,I., Basurto-Celaya,G., Perez-Guille,G., Possani,L.D., Calderon-Aranda,E.S.. Serum level of scorpion toxins, electrolytes and electrocardiogram alterations in Mexican children envenomed by scorpion sting. Toxicon, 122, 103-108.
Open Access Artículo
Artículo
Open Access Artículo
Open Access Revisión
Artículo
608 - Valdez-Velazquez,L.L., Romero-Gutierrez,M.T., Delgado-Enciso,I., Dobrovinskaya,O., Melnikov,V., Quintero-Hernandez,V., Ceballos-Magana,S.G., Gaitan-Hinojosa,M.A., Coronas,F.I., Puebla-Perez,A.M., Zamudio,F., De la Cruz-Garcia,I, Vazquez-Vuelvas,O.F., Soriano-Hernandez,A.D., Possani,L.D.. Comprehensive analysis of venom from the scorpion Centruroides tecomanus reveals compounds with antimicrobial, cytotoxic, and insecticidal activities. Toxicon, 118, 95-103.
Artículo
609 - Xiao,L., Gurrola,G.B., Zhang,J., Valdivia,C.R., SanMartin,M., Zamudio,F.Z., Zhang,L., Possani,L.D., Valdivia,H.H.. Structure-function relationships of peptides forming the calcin family of ryanodine receptor ligands. Journal of General Physiology, 147 (5), 375-394.
Artículo
610 - Zhang,H., Du,M., Xie,J., Liu,X., Sun,J., Wang,W., Xin,X., Possani,L.D., Yea,K., Lerner,R.A.. Autocrine-Based Selection of Drugs that Target Ion Channels from Combinatorial Venom Peptide Libraries. Angewandte Chemie International Edition, 55 (32), 9306-9310.
Artículo
Artículo
612 - Espino-Solis,G.P., Quintero-Hernandez,V., Olvera-Rodriguez,A., Calderon-Amador,J., Pedraza-Escalona,M., Licea-Navarro,A., Flores-Romo,L., Possani,L.D.. Novel monoclonal antibody against alphaX subunit from horse CD11c/CD18 integrin. Veterinary Immunology and Immunopathology, 164 (3-4), 220-226.
Open Access Artículo
Artículo
614 - Okada,M., Corzo,G., Romero-Perez,G.A., Coronas,F., Matsuda,H., Possani,L.D.. A pore forming peptide from spider Lachesana sp. venom induced neuronal depolarization and pain. Biochimica et Biophysica Acta (BBA) - General Subjects, 1850 (4), 657-666.
Open Access Revisión
615 - Ortiz,E., Possani,L.D.. The unfulfilled promises of scorpion insectotoxins. Journal of Venomous Animals and Toxins Including Tropical Diseases, 21, 16.
Revisión
Open Access Artículo
Artículo
Artículo
Artículo
Artículo
Artículo
Artículo
623 - Luna-Ramirez,K., Sani,M.A., Silva-Sanchez,J., Jimenez-Vargas,J.M., Reyna-Flores,F., Winkel,K.D., Wright,C.E., Possani,L.D., Separovic,F.. Membrane Interactions and Biological Activity of Antimicrobial Peptides from Australian Scorpion. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1838 (9), 2140-2148.
Artículo
624 - Ortiz,E., Rendon-Anaya,M., Rego,S.C., Schwartz,E.F., Possani,L.D.. Antarease-like Zn-metalloproteases are ubiquitous in the venom of different scorpion genera. Biochimica et Biophysica Acta (BBA) - General Subjects, 1840 (6), 1738-1746.
Artículo
Artículo
626 - Picco,C., Corzo,G., Possani,L.D., Prestipino,G.. Interaction of the scorpion toxin Discrepin with Kv4.3 channels and A-type K channels in cerebellum granular cells. Biochimica et Biophysica Acta (BBA) - General Subjects, 1840 (9), 2744-2751.
Artículo
Artículo
Internacional
629 - Abdel-Rahman,M.A., Quintero-Hernandez,V., Possani,L.D.. Scorpion Venom Gland Transcriptomics and Proteomics: An Overview. Venom Genomics and Proteomics. 105-124.
Internacional
630 - Rodriguez de la Vega,R.C., Corzo,G., Possani,L.D.. Scorpion Venoms as a Platform for Drug Development. Venoms to Drugs: Venom as a Source for the Development of Human Therapeutics. 204-220, Cambridge: Royal Society of Chemistry.
Internacional
Internacional
632 - Gopalakrishnakone, P., Possani, L. D., Schwartz, E., Rodriguez-de-la-Vega, R.. Scorpion Venoms. Toxinology, Dordrecht: Springer.
Open Access Divulgación
Artículo
Artículo; Actas Paper
635 - Aguilar,M.B., Ortiz,E., Kaas,Q., Lopez-Vera,E., Becerril,B., Possani,L.D., de la Cotera,E.P.. Precursor De13.1 from Conus delessertii defines the novel G gene superfamily. Peptides, 41, 17-20.
Open Access Artículo
636 - Bernaldez,J., Roman-Gonzalez,S.A., Martinez,O., Jimenez,S., Vivas,O., Arenas,I., Corzo,G., Arreguin,R., Garcia,D.E., Possani,L.D., Licea,A.. A Conus regularis Conotoxin with a Novel Eight-Cysteine Framework Inhibits CaV2.2 Channels and Displays an Anti-Nociceptive Activity. Marine Drugs, 11 (4), 1188-1202.
Artículo
Artículo
638 - Deuis,J.R., Zimmermann,K., Romanovsky,A.A., Possani,L.D., Cabot,P.J., Lewis,R.J., Vetter,I.. An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Na1.6 in peripheral pain pathways. Pain, 154 (9), 1749-1757.
Artículo
Artículo
Artículo
641 - Mourao,C.B., Heghinian,M.D., Barbosa,E.A., Mari,F., Bloch,C.,Jr., Restano-Cassulini,R., Possani,L.D., Schwartz,E.F.. Characterization of a novel peptide toxin from Acanthoscurria paulensis spider venom: a distinct cysteine assignment into the HWTX-II family. Biochemistry, 52 (14), 2440-2452.
Open Access Artículo
Revisión
Artículo
Open Access Artículo
645 - Rodriguez-Ravelo,R., Coronas,F.I., Zamudio,F.Z., Gonzalez-Morales,L., Lopez,G.E., Urquiola,A.R., Possani,L.D.. The Cuban scorpion Rhopalurus junceus (Scorpiones, Buthidae): component variations in venom samples collected in different geographical areas. Journal of Venomous Animals and Toxins Including Tropical Diseases, 19 (1), 13.
Artículo
646 - Sanchez-Vasquez,L., Silva-Sanchez,J., Jimenez-Vargas,J.M., Rodriguez-Romero,A., Munoz-Garay,C., Rodriguez,M.C., Gurrola,G.B., Possani,L.D.. Enhanced antimicrobial activity of novel synthetic peptides derived from vejovine and hadrurin. Biochimica et Biophysica Acta (BBA) - General Subjects, 1830 (6), 3427-3436.
Artículo
647 - Schwartz,E.F., Bartok,A., Schwartz,C.A., Papp,F., Gomez-Lagunas,F., Panyi,G., Possani,L.D.. OcyKTx2, a new K-channel toxin characterized from the venom of the scorpion Opisthacanthus cayaporum. Peptides, 46, 40-46.
Open Access Artículo
Internacional
649 - Petricevich,V.L., Barbosa-Navarro,L., Possani,L.D.. Therapeutic use of scorpion venom. Molecular aspects of inflammation. 209-231, Kerala: Research Signpost.
Internacional
650 - Rodriguez-de-la-Vega,R., Vidal,N., Possani,L.D.. Scorpion Peptides. Handbook of Biologically Active Peptides, second edition . 423-429.
Artículo
Artículo
Artículo
Artículo
Open Access Artículo
Artículo
656 - Gurrola,G.B., Hernandez-Lopez,R.A., Rodriguez de la Vega,R.C., Varga,Z., Batista,C.V., Salas-Castillo,S.P., Panyi,G., del Rio-Portilla,F., Possani,L.D.. Structure, function and chemical synthesis of Vaejovis mexicanus peptide 24: a novel potent blocker of Kv1.3 potassium channels of human T lymphocytes. Biochemistry, 51 (19), 4049-4061.
Artículo
Artículo
Artículo
Artículo
Open Access Artículo
Artículo
Open Access Artículo
663 - Saucedo,A.L., Flores-Solis,D., Rodriguez de la Vega,R.C., Ramirez-Cordero,B., Hernandez-Lopez,R., Cano-Sanchez,P., Noriega-Navarro,R., Garcia-Valdes,J., Coronas-Valderrama,F., de Roodt,A., Brieba,L.G., Possani,L.D., del Rio-Portilla,F.. New tricks of an old pattern: structural versatility of scorpion toxins with common cysteine spacing. Journal of Biological Chemistry, 287 (15), 12321-12330.
Artículo
664 - Saucedo,A.L., Del Rio,F., Picco,C., Estrada,G., Prestipino,G., Possani,L.D., Delepierre,M., Corzo,G.. Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion suffusus, and their effects on Nav1.5 Sodium channels. Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1824 (3), 478-487.
Artículo
Artículo
666 - Varga,Z., Gurrola-Briones,G., Papp,F., Rodriguez de la Vega,R.C., Pedraza-Alva,G., Tajhya,R.B., Gaspar,R., Cardenas,L., Rosenstein,Y., Beeton,C., Possani,L.D., Panyi,G.. Vm24, a Natural Immunosuppressant Peptide Potently and Selectively Blocks Kv1.3 Potassium Channels of Human T Cells. Molecular Pharmacology, 82 (3), 372-382.
Artículo
667 - Wang,X., Jimenez-Vargas,J.M., Xu,C., Possani,L.D., Zhu,S.. Positive selection-guided mutational analysis revealing two key functional sites of scorpion ERG K(+) channel toxins. Biochemical and Biophysical Research Communications, 429 (1-2), 111-116.
Artículo
Artículo
669 - Camargos,T.S., Restano-Cassulini,R., Possani,L.D., Peigneur,S., Tytgat,J., Schwartz,C.A., de Freitas,S.M., Schwartz,E.F.. The new kappa-KTx 2.5 from the scorpion Opisthacanthus cayaporum. Peptides, 32 (7), 1509-1517.
Open Access Artículo
Revisión
Artículo
Artículo
Artículo
Artículo
Artículo; Actas Paper
Revisión
Open Access Artículo
Artículo
Internacional
680 - Possani,L.D., Gurrola,G.B., Schwartz,E., Restano,R.. Bioquimica y biologia molecular de los venenos de escorpiones de importancia medica en el continente americano. Emergencias por Animales Ponzonosos en las Americas . 147-180, Mexico.
Internacional
681 - Valdez-Cruz,N.A., Conde,R., Zamudio,F., Possani,L.D.. Anticoagulants from scorpion venoms. Toxins and Hemostasis: From Bench to Bedside . 255-266.
Artículo
682 - de Roodt,A.R., Coronas,F.I., Lago,N., Gonzalez,M.E., Laskowicz,R.D., Beltramino,J.C., Saavedra,S., Lopez,R.A., Reati,G., Vucharchuk,M.G., Bazan,E., Varni,L., Salomon,O.D., Possani,L.D.. General biochemical and immunological characterization of the venom from the scorpion Tityus trivittatus of Argentina. Toxicon, 55 (2-3), 307-319.
Open Access Artículo
Open Access Artículo
684 - Redaelli,E., Restano-Cassulini,R., Fuentes-Silva,D., Clement,H., Schiavon,E., Zamudio,F.Z., Odell,G., Arcangeli,A., Clare,J.J., Alagon,A., Rodriguez de la Vega,R.C., Possani,L.D., Wanke,E.. Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels. Journal of Biological Chemistry, 285 (6), 4130-4142 .
Artículo; Actas Paper
685 - Rodriguez de la Vega,R.C., Schwartz,E.F., Possani,L.D.. Mining on scorpion venom biodiversity. Toxicon, 56 (7), 1155-1161.
Artículo
Artículo
687 - Zhu,S., Gao,B., Aumelas,A., Rodriguez,M.D., Lanz-Mendoza,H., Peigneur,S., Diego-Garcia,E., Martin-Eauclaire,M.F., Tytgat,J., Possani,L.D.. MeuTXKbeta1, a scorpion venom-derived two-domain potassium channel toxin-like peptide with cytolytic activity. Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1804 (4), 872-883.
Artículo
688 - Corzo,G., Bernard,C., Clement,H., Villegas,E., Bosmans,F., Tytgat,J., Possani,L.D., Darbon,H., Alagon,A.. Insecticidal peptides from the theraposid spider Brachypelma albiceps: A NMR-based model of Ba2. Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1794 (8), 1190-1196.
Artículo
689 - Corzo,G., Prochnicka-Chalufour,A., Garcia,B.I., Possani,L.D., Delepierre,M.. Solution structure of Cn5, a crustacean toxin found in the venom of the scorpions Centruroides noxius and Centruroides suffusus suffusus. Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1794 (11), 1591-1598.
Artículo
Revisión
Artículo
692 - Espino-Solis,G.P., Calderon-Amador,J., Calderon-Aranda,E.S., Licea,A.F., Donis-Maturano,L., Flores-Romo,L., Possani,L.D.. Rational design of synthetic peptides to generate antibodies that recognize in situ CD11c+ putative dendritic cells in horse lymph nodes. Veterinary Immunology and Immunopathology, 132 (2-4), 181-190.
Artículo
Artículo
Artículo
Artículo
696 - Kauferstein,S., Kendel,Y., Nicke,A., Coronas,F.I., Possani,L.D., Favreau,P., Krizaj,I., Wunder,C., Kauert,G., Mebs,D.. New conopeptides of the D-superfamily selectively inhibiting neuronal nicotinic acetylcholine receptors. Toxicon, 54 (3), 295-301.
Artículo
697 - Papp,F., Batista,C.V., Varga,Z., Herceg,M., Roman-Gonzalez,S.A., Gaspar,R., Possani,L.D., Panyi,G.. Tst26, a novel peptide blocker of Kv1.2 and Kv1.3 channels from the venom of Tityus stigmurus. Toxicon, 54 (4), 379-389.
Revisión
698 - Prestipino,G., Corzo,G., Romeo,S., Murgia,A.R., Zanardi,I., Gurrola,G., Possani,L.D.. Scorpion toxins that block transient currents (IA) of rat cerebellum granular cells. Toxicology Letters, 187 (1), 1-9.
Artículo
699 - Schwartz,E.F., Capes,E.M., Diego-Garcia,E., Zamudio,F.Z., Fuentes,O., Possani,L.D., Valdivia,H.H.. Characterization of hadrucalcin, a peptide from Hadrurus gertschi scorpion venom with pharmacological activity on ryanodine receptors. British Journal of Pharmacology, 157 (3), 392-403.
Artículo
700 - Silva,E.C., Camargos,T.S., Maranhao,A.Q., Silva-Pereira,I., Silva,L.P., Possani,L.D., Schwartz,E.F.. Cloning and characterization of cDNA sequences encoding for new venom peptides of the Brazilian scorpion Opisthacanthus cayaporum. Toxicon, 54 (3), 252-261.
Internacional
701 - Rodriguez-de-la-Vega,R., Barraza,R., Restano,R., Possani,L.D.. Toxins active on Herg channel: structure and function. Animal toxins: State of the Art. Perspectives in Health and Biotechnology . 193-204, Belo Horizonte: EditoraUFMG.
Artículo
702 - Abdel-Mottaleb,Y., Corzo,G., Martin-Eauclaire,M.F., Satake,H., Ceard,B., Peigneur,S., Nambaru,P., Bougis,P.E., Possani,L.D., Tytgat,J.. A common "hot spot" confers hERG blockade activity to alpha-scorpion toxins affecting K(+) channels. Biochemical Pharmacology, 76 (6), 805-815.
Artículo
703 - Carballar-Lejarazu,R., Rodriguez,M.H., De La Cruz Hernandez-Hernandez,F., Ramos-Castaneda,J., Possani,L.D., Zurita-Ortega,M., Reynaud-Garza,E., Hernandez-Rivas,R., Loukeris,T., Lycett,G., Lanz-Mendoza,H.. Recombinant scorpine: a multifunctional antimicrobial peptide with activity against different pathogens. Cellular and Molecular Life Sciences, 65 (19), 3081-3092.
Artículo
Artículo
Artículo
706 - Diego-Garcia,E., Abdel-Mottaleb,Y., Schwartz,E.F., de la Vega RC, Tytgat,J., Possani,L.D.. Cytolytic and K(+) channel blocking activities of beta-KTx and scorpine-like peptides purified from scorpion venoms. Cellular and Molecular Life Sciences, 65 (1), 187-200.
Artículo
Artículo
Artículo
709 - Petricevich,V.L., Reynaud,E., Cruz,A.H., Possani,L.D.. Macrophage activation, phagocytosis and intracellular calcium oscillations induced by scorpion toxins from Tityus serrulatus. Clinical and Experimental Immunology, 154 (3), 415-423.
Artículo
Artículo
711 - Romeo,S., Corzo,G., Vasile,A., Satake,H., Prestipino,G., Possani,L.D.. A positive charge at the N-terminal segment of Discrepin increases the blocking effect of K(+) channels responsible for the I(A) currents in cerebellum granular cells. Biochimica et Biophysica Acta (BBA) - General Subjects, 1780 (4), 750-755.
Artículo
712 - Schwartz,E.F., Camargos,T.S., Zamudio,F.Z., Silva,L.P., Bloch,C.,Jr., Caixeta,F., Schwartz,C.A., Possani,L.D.. Mass spectrometry analysis, amino acid sequence and biological activity of venom components from the Brazilian scorpion Opisthacanthus cayaporum. Toxicon, 51 (8), 1499-1508.
Nacional
713 - Possani-Postay,L.D.. El estudio de los componentes del veneno de alacranes en el contexto de la biología molecular, la farmacología y la medicina. Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 16. 179-187, Mexico, D.F..
Artículo
Artículo
Artículo; Actas Paper
Artículo
717 - Estrada,G., Garcia,B.I., Schiavon,E., Ortiz,E., Cestele,S., Wanke,E., Possani,L.D., Corzo,G.. Four disulfide-bridged scorpion beta neurotoxin CssII: Heterologous expression and proper folding in vitro. Biochimica et Biophysica Acta (BBA) - General Subjects, 1770 (8), 1161-1168.
Artículo
Artículo
Artículo
Artículo
Open Access Artículo
Artículo
Editorial Material
724 - Garcia,M.L., Possani,L.D.. Gating modifier peptides of ion channels. Toxicon, 49 (2), 123.
Artículo
Artículo
726 - Barona,J., Batista,C.V., Zamudio,F.Z., Gomez-Lagunas,F., Wanke,E., Otero,R., Possani,L.D.. Proteomic analysis of the venom and characterization of toxins specific for Na(+)- and K(+)-channels from the Colombian scorpion Tityus pachyurus. Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1764 (1), 76-84.
Artículo
727 - Batista,C.V., D'Suze,G., Gomez-Lagunas,F., Zamudio,F.Z., Encarnacion,S., Sevcik,C., Possani,L.D.. Proteomic analysis of Tityus discrepans scorpion venom and amino acid sequence of novel toxins. Proteomics, 6 (12), 3718-3727.
Artículo
Artículo
Revisión
730 - Panyi,G., Possani,L.D., Rodriguez de la Vega,R.C., Gaspar,R., Varga,Z.. K+ Channel Blockers: Novel Tools to Inhibit T Cell Activation Leading to Specific Immunosuppression. Current Pharmaceutical Design, 12 (18), 2199-2220.
Artículo
731 - Prochnicka-Chalufour,A., Corzo,G., Satake,H., Martin-Eauclaire,M.F., Murgia,A.R., Prestipino,G., D'Suze,G., Possani,L.D., Delepierre,M.. Solution Structure of Discrepin, a New K(+)-Channel Blocking Peptide from the alpha-KTx15 Subfamily(,). Biochemistry, 45 (6), 1795-1804.
Artículo; Actas Paper
732 - Restano-Cassulini,R., Korolkova,Y.V., Diochot,S., Gurrola,G., Guasti,L., Possani,L., Lazdunski,M., Grishin,E., Arcangeli,A., Wanke,E.. Species Diversity and Peptide Toxins Blocking Selectivity of ERG Subfamily K+ Channels in CNS. Molecular Pharmacology, 69 (5), 1673-1683.
Open Access Artículo
Artículo
Internacional
735 - Delepierre,M., Possani,L.D.. Pharmaceutical Applications of Ion Channel Blockers: Use of NMR to Determine the Structure of Scorpion Toxins. Modern Magnetic Resonance. 1325-1330, 2, Dordrecht: Springer.
Internacional
736 - Possani,L.D., Rodriguez de la Vega,R.C.. Scorpion venom peptides. Handbook of Biologically Active Peptides. 339-354, San Diego.
Artículo
737 - Aguilar,M.B., Lopez-Vera,E., Ortiz,E., Becerril,B., Possani,L.D., Olivera,B.M., Heimer de la Cotera,E.P.. A Novel Conotoxin from Conus delessertii with Posttranslationally Modified Lysine Residues. Biochemistry, 44 (33), 11130-11136.
Artículo
Open Access Artículo
Artículo
Revisión
741 - Gazarian,K.G., Gazarian,T., Hernandez,R., Possani,L.D.. Immunology of scorpion toxins and perspectives for generation of anti-venom vaccines. Vaccine, 23 (26), 3357-3368.
Artículo
Artículo
Artículo
Artículo
745 - Possani,L.D.. Insecticidal peptide from scorpion venom. Industrial Bioprocessing, 27 (2), 9-10.
Artículo
Revisión
Carta
Divulgación
749 - Possani,L.D.. El alacrán y su piquete. Mexico: Gobierno del Distrito Federal.
Artículo
750 - Batista,C.V., Del Pozo,L., Zamudio,F.Z., Contreras,S., Becerril,B., Wanke,E., Possani,L.D.. Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 803 (1), 55-66.
Artículo
Artículo
Artículo
753 - Frenal,K., Xu,C.Q., Wolff,N., Wecker,K., Gurrola,G.B., Zhu,S.Y., Chi,C.W., Possani,L.D., Tytgat,J., Delepierre,M.. Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K(+) channels. Proteins, 56 (2), 367-375.
Artículo
Open Access Artículo
755 - Huys,I., Olamendi-Portugal,T., Garcia-Gomez,B.I., Vandenberghe,I., Van Beeumen,J., Dyason,K., Clynen,E., Zhu,S., van der Walt,J., Possani,L., Tytgat,J.. A subfamily of acidic alpha -K+ toxins. Journal of Biological Chemistry, 279 (4), 2781-2789.
Artículo
756 - Montero-Solis,C., Gonzalez-Ceron,L., Rodriguez,M.H., Cirerol,B.E., Zamudio,F., Possanni,L.D., James,A.A., De La Cruz Hernandez-Hernandez,F.. Identification and characterization of gp65, a salivary-gland-specific molecule expressed in the malaria vector Anopheles albimanus. Insect Molecular Biology, 13 (2), 155-164.
Artículo
Artículo
758 - Pascual,I., Gil-Parrado,S., Cisneros,M., Joseph-Bravo,P., Diaz,J., Possani,L.D., Charli,J.L., Chavez,M.. Purification of a specific inhibitor of pyroglutamyl aminopeptidase II from the marine annelide Hermodice carunculata. In vivo effects in rodent brain. International Journal of Biochemistry and Cell Biology, 36 (1), 138-152.
Open Access Artículo
Artículo
Revisión
Artículo
Open Access Artículo
763 - Shalabi,A., Zamudio,F., Wu,X., Scaloni,A., Possani,L., Villereal,M.L.. Tetrapandins, a new class of scorpion toxins that specifically inhibit store-operated calcium entry in HEK-293 cells. Journal of Biological Chemistry, 279 (2), 1040-1049.
Open Access Artículo
Open Access Artículo
Artículo
Open Access Artículo
767 - Zhu,X., Zamudio,F.Z., Olbinski,B.A., Possani,L.D., Valdivia,H.H.. Activation of skeletal ryanodine receptors by two novel scorpion toxins from buthotus judaicus. Journal of Biological Chemistry, 279 (25), 26588-26596.
Artículo
768 - Corona,M., Coronas,F.V., Merino,E., Becerril,B., Gutierrez,R., Rebolledo-Antunez,S., Garcia,D.E., Possani,L.D.. A novel class of peptide found in scorpion venom with neurodepressant effects in peripheral and central nervous system of the rat. Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1649 (1), 58-67.
Artículo
Artículo
Artículo
Artículo
Artículo
773 - Guijarro,J.I., M'Barek,S., Gomez-Lagunas,F., Garnier,D., Rochat,H., Sabatier,J.M., Possani,L.D., Delepierre,M.. Solution structure of Pi4, a short four-disulfide-bridged scorpion toxin specific of potassium channels. Protein Science, 12 (9), 1844-1854.
Artículo
774 - Gutierrez,M.C., Abarca,C., Possani,L.D.. A toxic fraction from scolopendra venom increases the basal release of neurotransmitters in the ventral ganglia of crustaceans. Comparative Biochemistry and Physiology - C Toxicology and Pharmacology, 135 (2), 205-214.
Artículo
Artículo
Carta
777 - Xu,C.Q., Zhu,S.Y., Chi,C.W., Tytgat,J., Possani,L.D., Rodriguez de la Vega,R.C.. Turret and pore block of K+ channels: What is the difference? (multiple letters). Trends in Pharmacological Sciences, 24 (9), 446-449.
Nacional
778 - Alagon,A., Possani,L.D.. Desarrollo de nuevos f rmacos a partir de la fauna tropical. Fronteras de la Biología en los Inicios del Siglo XXI, Módulo VII . 123-160, Mexico,D.F..
Nacional
779 - Alagon,A., Carillo,C., Chavez-Haro,A., De la Mora-Zerpa,C., Larralde,C., Lamas,N, Martin,E, Osnaya-Romero,N., Perez,Y, Possani,L.D., Romero-Zamora,L.. Práctica Médica Efectiva- Alacranismo (T63.2, X22). Mexico.
Editorial Material
Editorial Material
781 - Possani,L.D.. The past, present, and future of biotechnology in Mexico. Nature Biotechnology, 21 (5), 582-583.
Editorial Material
Artículo
783 - Angulo,Y., Olamendi-Portugal,T., Alape-Giron,A., Possani,L.D., Lomonte,B.. Structural characterization and phylogenetic relationships of myotoxin II from Atropoides (Bothrops) nummifer snake venom, a Lys49 phospholipase A(2) homologue. International Journal of Biochemistry and Cell Biology, 34 (10), 1268-1278.
Artículo
Artículo
785 - Batista,C.V., Zamudio,F.Z., Lucas,S., Fox,J.W., Frau,A., Prestipino,G., Possani,L.D.. Scorpion toxins from Tityus cambridgei that affect Na(+)-channels. Toxicon, 40 (5), 557-562.
Artículo
Open Access Artículo
Artículo
788 - Lecchi,M., Redaelli,E., Rosati,B., Gurrola,G., Florio,T., Crociani,O., Curia,G., Cassulini,R.R., Masi,A., Arcangeli,A., Olivotto,M., Schettini,G., Possani,L.D., Wanke,E.. Isolation of a long-lasting eag-related gene-type K+ current in MMQ lactotrophs and its accommodating role during slow firing and prolactin release. Journal of Neuroscience, 22 (9), 3414-3425.
Artículo
789 - Olamendi-Portugal,T., Garcia,B.I., Lopez-Gonzalez,I., van der Walt,J., Dyason,K., Ulens,C., Tytgat,J., Felix,R., Darszon,A., Possani,L.D.. Two new scorpion toxins that target voltage-gated Ca(2+) and Na(+) channels. Biochemical and Biophysical Research Communications, 299 (4), 562-568.
Artículo
Open Access Artículo
791 - Pardo-Lopez,L., Zhang,M., Liu,J., Jiang,M., Possani,L.D., Tseng,G.N.. Mapping the binding site of a human ether-a-go-go-related gene-specific peptide toxin (ErgTx) to the channel's outer vestibule. Journal of Biological Chemistry, 277 (19), 16403-16411.
Artículo
792 - Possani,L.D., Corona,M., Zurita,M., Rodriguez,M.H.. From Noxiustoxin to Scorpine and Possible Transgenic Mosquitoes Resistant to Malaria. Archives of Medical Research, 33 (4), 398-404.
Artículo
Open Access Artículo
794 - Vacher,H., Alami,M., Crest,M., Possani,L.D., Bougis,P.E., Martin-Eauclaire,M.F.. Expanding the scorpion toxin alpha-KTX 15 family with AmmTX3 from Androctonus mauretanicus. European Journal of Biochemistry, 269 (24), 6037-6041.
Internacional
795 - Possani,L.D., Merino,E., Corona,M., Becerril,B.. Scorpion genes and peptides specific for potassium channels: Structure, function and evolution. Perspectives in Molecular Toxinology. 201-214.
Artículo
Artículo
Artículo
Artículo
799 - Goudet,C., Ferrer,T., Galan,L., Artiles,A., Batista,C.F., Possani,L.D., Alvarez,J., Aneiros,A., Tytgat,J.. Characterization of two Bunodosoma granulifera toxins active on cardiac sodium channels. British Journal of Pharmacology, 134 (6), 1195-1206.
Artículo
800 - Nishigaki,T., Zamudio,F.Z., Possani,L.D., Darszon,A.. Time-Resolved Sperm Responses to an Egg Peptide Measured by Stopped-Flow Fluorometry. Biochemical and Biophysical Research Communications, 284 (2), 531-535.
Artículo
801 - Peter,M.,Jr, Varga,Z., Hajdu,P., Gaspar,R., Damjanovich,S., Horjales,E., Possani,L.D., Panyi,G.. Effects of toxins Pi2 and Pi3 on human T lymphocyte Kv1.3 channels: the role of Glu7 and Lys24. Journal of Membrane Biology, 179 (1), 13-25.
Artículo
802 - Rocchetti,M., Besana,A., Gurrola,G.B., Possani,L.D., Zaza,A.. Rate dependency of delayed rectifier currents during the guinea-pig ventricular action potential. Journal of Physiology, 534 (Pt 3), 721-732.
Internacional
803 - Possani,L.D., Becerril,B., Tytgat,J., Delepierre,M.. High Affinity Scorpion Toxins for Studying Potassium and Sodium Channels. Ion Channel Localization Methods and Protocols: Methods and Protocols. 145-165.
Artículo
Artículo
Carta
Artículo
Artículo
808 - Peter,M.,Jr, Hajdu,P., Varga,Z., Damjanovich,S., Possani,L.D., Panyi,G., Gaspar,R.. Blockage of human T lymphocyte Kv1.3 channels by Pi1, a novel class of scorpion toxin. Biochemical and Biophysical Research Communications, 278 (1), 34-37.
Artículo
809 - Pisciotta,M., Coronas,F.I., Bloch,C., Prestipino,G., Possani,L.D.. Fast K(+) currents from cerebellum granular cells are completely blocked by a peptide purified from Androctonus australis Garzoni scorpion venom. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1468 (1-2), 203-212.
Artículo
Carta
811 - Possani,L.D.. Antivenom for scorpion sting. Lancet, 355 (9197), 67.
Open Access Artículo
Nacional
813 - Possani,L.D.. Alacranismo en Mexico. La salud en Durango, 1, 5-6.
Artículo
814 - Altamirano,M.M., Garcia,C., Possani,L.D., Fersht,A.R.. Oxidative refolding chromatography: folding of the scorpion toxin Cn5. Nature Biotechnology, 17 (2), 187-191.
Artículo
815 - Batista,C.V., da Silva,L.R., Sebben,A., Scaloni,A., Ferrara,L., Paiva,G.R., Olamendi-Portugal,T., Possani,L.D., Bloch,C.. Antimicrobial peptides from the Brazilian frog Phyllomedusa distincta. Peptides, 20 (6), 679-686.
Artículo
Open Access Artículo
Artículo
Artículo
819 - Delepierre,M., Prochnicka-Chalufour,A., Boisbouvier,J., Possani,L.D.. Pi7, an orphan peptide from the scorpion Pandinus imperator: a 1H-NMR analysis using a nano-NMR Probe. Biochemistry, 38 (51), 16756-16765.
Artículo
Open Access Artículo
821 - Gurrola,G.B., Rosati,B., Rocchetti,M., Pimienta,G., Zaza,A., Arcangeli,A., Olivotto,M., Possani,L.D., Wanke,E.. A toxin to nervous, cardiac, and endocrine ERG K+ channels isolated from Centruroides noxius scorpion venom. FASEB Journal, 13 (8), 953-962.
Artículo
822 - Ottolia,M., Babini,E., Gazzotti,P., Possani,L.D., Prestipino,G.. Reconstitution of a voltage and calcium dependent potassium channel from rat cerebellum. Brain Research, 815 (2), 410-413.
Artículo
Revisión
824 - Possani,L.D., Selisko,B., Gurrola,G.B.. Structure and function of scorpion toxins affecting K+-channels. Perspectives In Drug Discovery And Design, 16, 15-40.
Open Access Revisión
825 - Possani,L.D., Becerril,B., Delepierre,M., Tytgat,J.. Scorpion toxins specific for Na+-channels. European Journal of Biochemistry, 264 (2), 287-300.
Artículo
Artículo
827 - Tytgat,J., Chandy,K.G., Garcia,M.L., Gutman,G.A., Martin-Eauclaire,M.F., van der Walt,J.J., Possani,L.D.. A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies. Trends in Pharmacological Sciences, 20 (11), 444-447.
Artículo
Open Access Artículo
829 - Boisbouvier,J., Prochnicka-Chalufour,A., Nieto,A.R., Torres,J.A., Nanard,N., Rodriguez,M.H., Possani,L.D., Delepierre,M.. Structural information on a cecropin-like synthetic peptide, Shiva-3 toxic to the sporogonic development of Plasmodium berghei. European Journal of Biochemistry, 257 (1), 263-273.
Artículo
830 - Delepierre,M., Prochnicka-Chalufour,A., Possani,L.D.. 1H NMR structural analysis of novel potassium blocking toxins using a nano-NMR probe. Toxicon, 36 (11), 1599-1608.
Open Access Artículo
831 - Licea,A.F., Gutierrez,M.C., Esparza,J., Estrada-Parra,S., Estrada,G.I., Quesada-Pascual,F., Possani,L.D.. Enhancement of the immunogenicity of Mycobacterium leprae peptides by means of polymerization. Asia-Pacific Journal Of Molecular Biology And Biotechnology, 6 (2), 89-95.
Artículo
Artículo
Artículo
834 - Peter,M.,Jr, Varga,Z., Panyi,G., Bene,L., Damjanovich,S., Pieri,C., Possani,L.D., Gaspar,R.. Pandinus imperator scorpion venom blocks voltage-gated K+ channels in human lymphocytes. Biochemical and Biophysical Research Communications, 242 (3), 621-625.
Artículo
835 - Pisciotta,M., Ottolia,M., Possani,L.D., Prestipino,G.. A novel toxin form the scorpion Androctonus australis blocks Shaker K+ channels expressed in Xenopus oocytes. Biochemical and Biophysical Research Communications, 242 (2), 287-291.
Artículo
Artículo
837 - Possani,L.D., Zurita,M., Delepierre,M., Hernandez,F.H., Rodriguez,M.H.. From noxiustoxin to Shiva-3, a peptide toxic to the sporogonic development of Plasmodium berghei. Toxicon, 36 (11), 1683-1692.
Open Access Revisión
Artículo
839 - Tytgat,J., Debont,T., Rostoll,K., Muller,G.J., Verdonck,F., Daenens,P., van der Walt,J.J., Possani,L.D.. Purification and partial characterization of a 'short' insectotoxin-like peptide from the venom of the scorpion Parabuthus schlechteri. FEBS Letters, 441 (3), 387-391.
Artículo
840 - Valdivia,H.H., Possani,L.D.. Peptide toxins as probes of ryanodine receptor structure and function. Trends in Cardiovascular Medicine, 8 (3), 111-118.
Revisión
Artículo
842 - Ben Khalifa,R., Stankiewicz,M., Pelhate,M., Serrano-Hernandez,S.E., Possani,L.D., Hinkel,H., Mebs,D.. Action of babycurus-toxin 1 from the east African scorpion Babycurus centrurimorphus on the isolated cockroach giant axon. Toxicon, 35 (7), 1069-1080.
Artículo
Artículo
844 - Garcia,C., Becerril,B., Selisko,B., Delepierre,M., Possani,L.D.. Isolation, characterization and comparison of a novel crustacean toxin with a mammalian toxin from the venom of the scorpion Centruroides noxius Hoffmann. Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, 116 (3), 315-322.
Artículo
Artículo
Artículo
Open Access Artículo
Artículo
Artículo
Artículo
Artículo
Artículo
Artículo
Artículo
Artículo
Artículo
857 - Nobile,M., Noceti,F., Prestipino,G., Possani,L.D.. Helothermine, a lizard venom toxin, inhibits calcium current in cerebellar granules. Experimental Brain Research, 110 (1), 15-20.
Artículo
Open Access Artículo
Artículo
860 - Vaca,L., Licea,A., Possani,L.D.. Modulation of cell membrane potential in cultured vascular endothelium. American Journal of Physiology - Cell Physiology, 270 (3 Pt 1), C819-C824.
Artículo
Internacional
862 - Calderon-Aranda,E.S., Dehesa-Davila,M., Chavez-Haro,A., Possani,L.D.. Scorpion stings and their treatment in Mexico. Envenomings and their treatment. 311-320, Lyon.
Artículo
Artículo
Artículo
Artículo
866 - Drakopoulou,E., Cotton,J., Virelizier,H., Bernardi,E., Schoofs,A.R., Partiseti,M., Choquet,D., Gurrola,G., Possani,L.D., Vita,C.. Chemical synthesis, structural and functional characterisation of noxiustoxin, a powerful blocker of lymphocyte voltage-dependent K+ channels. Biochemical and Biophysical Research Communications, 213 (3), 901-907.
Artículo
867 - Gaspar,R., Bene,L., Damjanovich,S., Munoz-Garay,C., Calderon-Aranda,E.S., Possani,L.D.. Beta-scorpion toxin 2 from Centruroides noxius blocks voltage-gated K+ channels in human lymphocytes. Biochemical and Biophysical Research Communications, 213 (2), 419-423.
Artículo
868 - Gurrola,G.B., Possani,L.D.. Structural and functional features of noxiustoxin: a K+ channel blocker. Biochemistry and Molecular Biology International, 37 (3), 527-535.
Artículo
869 - Herion,P., Gurrola-Briones,G., Sanchez,M.D.R., Saavedra,R., Possani,L.D.. Monoclonal antibodies against noxiustoxin. Hybridoma, 14 (3), 247-251.
Artículo
870 - Morrissette,J., Kratzschmar,J., Haendler,B., Elhayek,R., Mochca-Morales,J., Martin,B.M., Patel,J.R., Moss,R.L., Schleuning,W.D., Coronado,R., Possani,L.D.. Primary Structure and Properties of Helothermine, A Peptide Toxin That Blocks Ryanodine Receptors. Biophysical Journal, 68 (6), 2280-2288.
Artículo
Open Access Artículo
872 - Noeske-Jungblut,C., Haendler,B., Donner,P., Alagon,A., Possani,L., Schleuning,W.D.. Triabin, a highly potent exosite inhibitor of thrombin. Journal of Biological Chemistry, 270 (48), 28629-28634.
Note
Note
Note
Note
Note
Note
Artículo
879 - Rodriguez,M.C., Zamudio,F., Torres,J.A., Gonzalez-Ceron,L., Possani,L.D., Rodriguez,M.H.. Effect of a cecropin-like synthetic peptide (Shiva-3) on the sporogonic development of Plasmodium berghei. Experimental Parasitology, 80 (4), 596-604.
Artículo
880 - Trequattrini,C., Zamudio,F.Z., Petris,A., Prestipino,G., Possani,L.D., Franciolini,F.. Tityus bahiensis toxin IV-5b selectively affects Na channel inactivation in chick dorsal root ganglion neurons. Comparative Biochemistry and Physiology -- Part A: Physiology, 112 (1), 21-28.
Artículo
Internacional
882 - Dehesa-Davila,M., Alagon,A.C., Possani,L.D.. Clinical toxicology of scorpion stings. Handbook of clinical toxicology of animal venoms and poisons. 221-238, New York.
Artículo
Artículo
Artículo
Artículo
Artículo
887 - Gutierrez,M.C., ESTRADA,I.C.E., Estrada-Parra,S., Quesada-Pascual,F., Licea,A.F., Possani,L.D.. The imunogenetic activity of synthetic peptides corresponding to M. Leprae protein sequences. Asia-Pacific Journal Of Molecular Biology And Biotechnology, 2, 143-150.
Artículo; Actas Paper
Artículo
Artículo
890 - Martin,B.M., Ramirez,A.N., Gurrola,G.B., Nobile,M., Prestipino,G., Possani,L.D.. Novel K(+)-channel-blocking toxins from the venom of the scorpion Centruroides limpidus limpidus Karsch. Biochemical Journal, 304 (Pt 1), 51-56.
Artículo
891 - Nobile,M., Magnelli,V., Lagostena,L., Mochca-Morales,J., Possani,L.D., Prestipino,G.. The toxin helothermine affects potassium currents in newborn rat cerebellar granule cells. Journal of Membrane Biology, 139 (1), 49-55.
Open Access Artículo
892 - Noeske-Jungblut,C., Kratzschmar,J., Haendler,B., Alagon,A., Possani,L., Verhallen,P., Donner,P., Schleuning,W.D.. An inhibitor of collagen-induced platelet aggregation from the saliva of Triatoma pallidipennis. Journal of Biological Chemistry, 269 (7), 5050-5053.
Artículo
Artículo
894 - Sacile,R., Ruggiero,C., Ballestrero,R., Possani,L.D., Prestipino,G., Rauch,G.. Secondary structure of noxiustoxin and charybdotoxin from hydropathy power spectra. Biochemical and Biophysical Research Communications, 201 (1), 186-193.
Artículo
895 - Valdivia,H.H., Martin,B.M., Ramirez,A.N., Fletcher,P.L., Possani,L.D.. Isolation and pharmacological characterization of four novel Na+ channel-blocking toxins from the scorpion Centruroides noxius Hoffmann. Journal of Biochemistry, 116 (6), 1383-1391.
Open Access Artículo
901 - Estrada,I.C., Gutierrez,M.C., Esparza,J., Quesada-Pascual,F., Estrada-Parra,S., Possani,L.D.. Use of synthetic peptides corresponding to sequences of Mycobacterium leprae proteins to study delayed-type hypersensitivity response in sensitized guinea pigs. International Journal of Leprosy, 60 (1), 18-27.
Artículo
902 - Fletcher,P.L., Fletcher,M.D., Possani,L.D.. Characteristics of pancreatic exocrine secretion produced by venom from the Brazilian scorpion, Tityus serrulatus. European Journal of Cell Biology, 58 (2), 259-270.
Note
903 - Harvey,A.L., Marshall,D.L., Possani,L.D.. Dendrotoxin-like effects of noxiustoxin. Toxicon, 30 (11), 1497-1500.
Open Access Artículo
904 - Possani,L.D., Fletcher,P.L., Fletcher,M.D., Rode,G.S., Mochca-Morales,J., Lucas,S., Coronas,F.V., Alagon,A.C., Martin,B.M.. Structural and functional characteristics of toxins purified from the venom of the Brazilian scorpion Tityus serrulatus Lutz and Mello. Memorias do Instituto Butantan, 54 (2), 35-52.
Artículo
905 - Possani,L.D., Mochca-Morales,J., Amezcua,J., Martin,B.M., Prestipino,G., Nobile,M.. Anionic currents of chick sensory neurons are affected by a phospholipase A2 purified from the venom of the taipan snake. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1134 (3), 210-216.
Artículo
Artículo
907 - Valdivia,H.H., Martin,B.M., Escobar,L., Possani,L.D.. Noxiustoxin and leiurutoxin III, two homologous peptide toxins with binding properties to synaptosomal membrane K+ channels. Biochemistry International, 27 (6), 953-962.
Open Access Artículo
Open Access Artículo
909 - Possani,L.D., Martin,B.M., Fletcher,M.D., Fletcher,P.L.. Discharge effect on pancreatic exocrine secretion produced by toxins purified from Tityus serrulatus scorpion venom. Journal of Biological Chemistry, 266 (5), 3178-3185.
Memoria in extenso
910 - Gutierrez,M.C., Estrada,G.I., Estrada-Parra,S., Gurrola,G.B., Possani,L.D.. Synthetic peptides as skin test reagents in leprosy. Proceedings Leprosy Research in Latin America. 7 p, Caracas.
Memoria in extenso
911 - Possani,L.D., Gurrola,G.B., Portugal,T.O., Zamudio,F.Z., Vaca,L.D., Calderon,S.A., Kirsch,G.E.. Scorpion toxins: a model for peptide synthesis of new drugs. Proceedings First Brazilian Congress on Proteins. 352-367, Brasil.
Artículo
Artículo
917 - Kirsch,G.E., Skattebol,A., Possani,L.D., Brown,A.M.. Modification of Na channel gating by an alpha scorpion toxin from Tityus serrulatus. Journal of General Physiology, 93 (1), 67-83.
Artículo
918 - Prestipino,G., Valdivia,H.H., Lievano,A., Darszon,A., Ramirez,A.N., Possani,L.D.. Purification and reconstitution of potassium channel proteins from squid axon membranes. FEBS Letters, 250 (2), 570-574.
Artículo
919 - Alagon,A.C., Guzman,H.S., Martin,B.M., Ramirez,A.N., Carbone,E., Possani,L.D.. Isolation and characterization of two toxins from the Mexican scorpion Centruroides limpidus limpidus Karsch. Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, 89 (1), 153-161.
Artículo
Artículo
Artículo
922 - Valdivia,H.H., Smith,J.S., Martin,B.M., Coronado,R., Possani,L.D.. Charybdotoxin and noxiustoxin, two homologous peptide inhibitors of the K+ (Ca2+) channel. FEBS Letters, 226 (2), 280-284.
Artículo
923 - Yatani,A., Kirsch,G.E., Possani,L.D., Brown,A.M.. Effects of New World scorpion toxins on single-channel and whole cell cardiac sodium currents. American Journal of Physiology Heart and Circulatory Physiology, 254 (3 Pt 2), H443-H451.
Artículo
924 - Brown,A.M., Yatani,A., Lacerda,A.E., Gurrola,G.B., Possani,L.D.. Neurotoxins that act selectively on voltage-dependent cardiac calcium channels. Circulation Research, 61 (4 Pt 2), I6-I9.
Artículo
925 - Carbone,E., Prestipino,G., Spadavecchia,L., Franciolini,F., Possani,L.D.. Blocking of the squid axon K+ channel by noxiustoxin: a toxin from the venom of the scorpion Centruroides noxius. Pflugers Archiv European Journal of Physiology, 408 (5), 423-431.
Artículo
Artículo
Artículo
928 - Rodriguez,A., Tablero,M., Barragan,B., Lara,P., Rangel,M., Arreguin,B., Possani,L., Soriano-Garcia,M.. Crystallization of Hevein - A Protein from Latex of Hevea-Brasiliensis (Rubber Tree). Journal of Crystal Growth, 76 (3), 710-714. *
Artículo
Artículo
Artículo
931 - Possani,L.D., Martin,B.M., Svendsen,I., Rode,G.S., Erickson,B.W.. Scorpion toxins from Centruroides noxius and Tityus serrulatus. Primary structures and sequence comparison by metric analysis. Biochemical Journal, 229 (3), 739-750. *
Artículo
932 - Carbone,E., Prestipino,G., Franciolini,F., Dent,M.A., Possani,L.D.. Selective modification of the squid axon Na currents by Centruroides noxius toxin II-10. Journal de Physiologie, 79 (4), 179-184. *
Nacional
933 - Gurrola,G.B., Molina-Rode,R., Zentella,A.D., Possani,L.D.. Sintesis de peptidos y su posible utilizacion como vacuna contra toxinas de alacran. Avances en el mecanismo de accion de farmacos. 35-50.
Internacional
934 - Possani,L.D.. Structure of scorpion toxins. Handbook of natural toxins. 513-550, New York. *
Nacional
935 - Domingos Possani,L.. The toxins of scorpion venom: structure and function. Boletin de estudios medicos y biologicos, 32 (7-8 Suppl 1), 285-297.
Artículo
Artículo
937 - Carbone,E., Wanke,E., Prestipino,G., Possani,L.D., Maelicke,A.. Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin. Nature, 296 (5852), 90-91. *
Artículo
938 - Carbone,E., Wanke,E., Prestipino,G., Possani,L.D., Maelicke,A.. Selective Action of Purified Scorpion Neurotoxins on the Ionic Currents of the Squid Giant-Axon. Hoppe-Seylers Zeitschrift fur Physiologische Chemie, 363 (2), 1299-1300. *
Open Access Artículo
Artículo
Artículo
941 - Perez de la Mora,M., Possani,L.D., Tapia,R., Teran,L., Palacios,R., Fuxe,K., Hokfelt,T., Ljungdahl,A.. Demonstration of central gamma-aminobutyrate-containing nerve terminals by means of antibodies against glutamate decarboxylase. Neuroscience, 6 (5), 875-895. *
Artículo
942 - Possani,L., Steinmetz,W.E., Dent,M.A., Alagon,A.C., Wuthrich,K.. Preliminary spectroscopic characterization of six toxins from Latin American scorpions. Biochimica et Biophysica Acta (BBA) - Protein Structure, 669 (2), 183-192. *
Open Access Artículo
943 - Possani,L.D., Dent,M.A.R., Martin,B.M., Maelicke,A., Svendsen,I.. The Amino Terminal Sequence of Several Toxins from the Venom of the Mexican Scorpion Centruroides Noxius Hoffmann. Carlsberg Research Communications, 46 (4), 207-214. *
Open Access Artículo
944 - Possani,L.D., Martin,B.M., Mochcamorales,J., Svendsen,I.. Purification and Chemical Characterization of the Major Toxins from the Venom of the Brazilian Scorpion Tityus Serrulatus Lutz and Mello. Carlsberg Research Communications, 46 (4), 195-205. *
Note
945 - Possani,L.D., Fernandez de Castro,J., Julia,J.Z.. Detoxification with glutaraldehyde of purified scorpion (Centruroides noxius Hoffmann) venom. Toxicon, 19 (2), 323-329. *
Memoria in extenso
946 - Perez de la Mora,M., Fuxe,K., Hokfelt,T., Anderson,K., Possani,L., Tapia,R.. Gabaergic synapses: distribution and interaction with other Neurotransmitter systems in the brain. Regulatory Mechanisms of Synaptic Transmission. 71-101, Boston,MA. *
Artículo
Artículo
952 - Sosa,B.P., Alagon,A.C., Possani,L.D., Julia,J.Z.. Comparison of phospholipase activity with direct and indirect lytic effects of animal venoms upon human red cells. Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 64 (2), 231-234. *
Internacional
953 - Fuxe,K., Andersson,K., Schwarcz,R., Agnati,L.F., Perez de la Mora,M., Hokfelt,T., Goldstein,M., Ferland,L., Possani,L., Tapia,L.. Studies on different types of dopamine nerve terminals in the forebrain adn their possible interactions with neurons. Advances in neurology. Advances in neurology, 199-216, New York. *
Memoria in extenso
954 - Perez de la Mora,M., Fuxe,K., Andersson,K., Hokfelt,T., Ljungdahl,A., Possani,L., Tapia,R.. STUDIES ON GABA-MONOAMINE AND GABA-ENDORPHIN INTERACTIONS. Catecholamines: Basic and Clinical Frontiers Proceedings of the Fourth International Catecholamine Symposium, Pacific Grove, California, September 17-22, 1978. 1032-1034. *
Note
955 - Bayon,A., Possani,L.D., Rode,G., Tapia,R.. Kinetics of brain glutamate decarboxylase. Dead-end and product inhibition studies. Journal of Neurochemistry, 30 (6), 1629-1631. *
Artículo
956 - Hokfelt,T., Elde,R., Fuxe,K., Johansson,O., Ljungdahl,A., Goldstein,M., Luft,R., Efendic,S., Nilsson,G., Terenius,L., Ganten,D., Jeffcoate,S.L., Rehfeld,J., Said,S., Perez de la Mora,M., Possani,L., Tapia,R., Teran,L., Palacios,R.. Aminergic and peptidergic pathways in the nervous system with special reference to the hypothalamus. Research publications - Association for Research in Nervous and Mental Disease, 56, 69-135. *
Artículo
957 - Possani,L.D., Ramirez,G.A., Fletcher,P.L., Gurrola,M.A.. Isolation of two mammalian toxins from the venom of the Mexican scorpion Centruroides elegans (Thorell). FEBS Letters, 91 (2), 261-264. *
Internacional
958 - Alagon,A.C., Possani,L.D., Erickson,B.W.. ISOLATION AND CHARACTERIZATION OF SEVERAL PROTEINS FROM TITYUS SERRULATUS SCORPION VENOM. Toxins Animal, Plant and Microbial. 609-618. *
Internacional
959 - Fuxe,K., Hokfelt,T., Agnati,L.F., Johansson,O., Goldstein,M., Perez de la Mora,M., Possani,L., Tapia,R., Teran,L., Palacios,R.. Mapping out central catecholamine synthesizing neurons: immunohistochemical studies on catecholamine-synthesizing enzymes. Psychopharmacology: a Generation of Progress. 67-94, New York. *
Artículo
Artículo
961 - Bayon,A., Possani,L.D., Tapia,R.. Kinetics of brain glutamate decarboxylase. Inhibition studies with N-(5'-phosphopyridoxyl) amino acids. Journal of Neurochemistry, 29 (3), 513-517. *
Artículo
Artículo
963 - Possani,L.D., Alagon,A.C., Fletcher,P.L., Erickson,B.W.. Purification and properties of mammalian toxins from the venom of Brazilian Scorpion Tityus serrulatus Lutz and Mello. Archives of Biochemistry and Biophysics, 180 (2), 394-403. *
Open Access Artículo
964 - Klett,R.P., Fulpius,B.W., Cooper,D., Smith,M., Reich,E., Possani,L.D.. The acetylcholine receptor. I. Purification and characterization of a macromolecule isolated from Electrophorus electricus. Journal of Biological Chemistry, 248 (19), 6841-6853. *
Artículo
965 - Possani,L.D.. GABA effects and GABA receptors in neuromuscular junctions of crustaceans: analysis of some stereochemical models. Revista brasileira de pesquisas medicas e biologicas, 6 (1), 31-42. *
Artículo
966 - Tondo,C.V., Possani,L.D.. Study of the bimodal frequency distribution of the relative concentration of hemoglobin S in heterozygous carriers. Revista brasileira de pesquisas medicas e biologicas, 5 (1-2), 47-56. *
Artículo
967 - Possani,L.D., Banerjee,R., Balny,C., Douzou,P.. Oxidation of haemoglobin by oxygen in light: possible role of singlet oxygen. Nature, 226 (248), 861-862. *

  • Teléfonos
  • Oficina +52 (777) 329-1647
    desde la CDMX 562-27647
    Red UNAM 27647