Dra. Patricia Ileana Joseph Bravo
Investigador
Neurobiología Celular y Molecular
Número de registros: 18
- Activos
- Vencidos
- Caracterización del efecto del estrés crónico e intermitente, a largo plazo, sobre la respuesta del eje tiroideo y el metabolismo., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2019 - 2021
- Efecto del estrés durante adolescencia sobre la respuesta del eje hipotálamo-pituitaria-tiroides a retos metabólicos y su repercusión en la homeostasis energética del roedor adulto de ambos sexos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2018 - 2021
- Efecto del estrés crónico en la respuesta de las neuronas trhérgicas y el eje tiroideo ante retos de demanda energética, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2016 - 2019
- Aspectos moleculares y celulares de la comunicación peptidérgica en el sistema nervioso, PRESUPUESTO UNAM, 2014 - 2020
- Dinámica de los efectos de glucocorticoides en la respuesta de las neuronas trhérgicas hipofisiotrópicas y el eje tiroideo a estímulos de demanda energética, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2013 - 2016
- Efectos del estrés postnatal sobre la respuesta del eje hipotálamo-pituitaria-tiroides a retos metabólicos. búsqueda de cambios epigenéticos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2012 - 2016
- Efecto de glucocorticoides y hormonas tiroideas en la regulación neuronal de la transcripción del gen de trh, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2010 - 2012
- Cambios en la conducta de ansiedad y en la transformacion thrergica del sistema limbico en ratas sometidas a un estrés agudo, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2009
- Efecto del estrés sobre la actividad de las neuronas trhérgicas del sistema límbico, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2008 - 2011
- Respuesta de las neuronas trhérgicas del sistema límbico al estrés, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2007 - 2009
- Estudios sobre la función del trh en el sistema límbico, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2004 - 2007
- Estudio sobre la biosíntesis del trh en el eje neuroendócrino., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2004 - 2005
- El trh como neuromodulador en el sistema límbico., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2004 - 2005
- Efectos de los glucocorticoides sobre la expresión del protrh., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2003
- Regulación de la biosíntesis de trh en el núcleo paraventricular del hipotálamo (iii)., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2000 - 2003
- Regulación del metabolismo de trh en el sistema nervioso central (iv)., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2000 - 2003
- Regulación de la biosíntesis de trh en el núcleo paraventricular: vías y mecanismos de regulación (ii), CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1998 - 2001
- Regulación del metabolismo del trh en el sistema nervioso ii, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 1997 - 2000
Nivel d del Pride
Nivel III del SNI
Nivel III del SNI
Doctorado, en Bioquímica, Universidad de Londres, Colegio Imperial de Ciencia y Tecnología
Maestría, en Nutricion y Metabolismo. Mass. Inst. of Technology, Cambridge, Mass E.U.A. Dept. de Ciencia en Nutrición y Metabolismo (1974)
Licenciatura, Química, Fac. de Química-UNAM (1970)
Miembro del Consejo Consultivo de Posgrado de la UNAM, 2003
Distinción Juana Ramírez de Abaje, UNAM, 2003
Premio Miguel Aleman, 1988
-
Doctorado
-
Caracterización de los circuitos noradrenérgicos involucrados en la respuesta del eje HPT al frío
-
M.C. Marco Antonio Parra Montes de oca
El estrés durante la adolescencia de ratas modifica su respuesta a retos metabólicos. -
Cambios epigenéticos en el promotor de TRH en respuesta al estrés perinatal
-
Maestría
-
El estrés durante la adolescencia modifica la respuesta del eje tiroideo al ejercicio.
-
Licenciatura
1 - Gutierrez Mata, Angelica (2020). El estres durante la adolescencia modifica la respuesta del eje tiroideo al ejercicio.
Instituto de Biotecnologia,
Maestría en Ciencias Bioquímicas,
UNAM.
Asesor: Joseph-Bravo, Patricia
2 - Castillo Campos, Andrea (2019). Efecto del estres cronico variable sobre el eje hipotalamopituitariatiroides en respuesta al frio .
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Joseph-Bravo, Patricia
3 - Velazquez Vazquez, Diana Elisa (2018). Estudio de la interaccion entre el receptor de glucocorticoides y la subunidad catalitica de PKA en la regulacion de la expresion del gen pro-TRH .
Facultad de Ciencias,
Licenciatura en Biologia,
UNAM.
Asesor: Joseph-Bravo, Patricia
4 - Sotelo Rivera, Israim (2017). Regulacion dinamica de la senalizacion de glucocorticoides en la expresion de TRH y el funcionamiento del eje tiroideo .
Instituto de Biotecnologia,
Doctorado en Bioquimicas,
UNAM.
Asesor: Joseph-Bravo, Patricia
5 - Sotelo Rivera, Israim (2012). Estudio del mecanismo molecular de la interferencia entre el receptor de glucocorticoides y la senal de AMPc en el gen proTRH.
Instituto de Biotecnologia,
Maestria en Ciencias (Bioquimicas),
UNAM.
Asesor: Joseph-Bravo, Patricia
6 - Perez Maldonado, Adrian (2012). Analisis molecular de los sitios cre y las secuencias adyacentes en el contexto del promotor del gen de trh en respuesta a la estimulacion con t3 y activadores de la pka.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Joseph-Bravo, Patricia
7 - Perez Maldonado, Adrian (2010). Determinacion del papel transcripcional del sitio CRE-1 del promotor del gen de TRH.
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
Asesor: Joseph-Bravo, Patricia
8 - Gutierrez Mariscal, Mariana (2010). Participacion de las neuronas TRHergicas amigdalinas en la conducta de ansiedad .
Instituto de Biotecnologia,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Joseph-Bravo, Patricia
9 - Horjales Araujo, Maria Emilia (2007). Efecto de una dieta a base de tortillas en el comportamiento alimenticio y el metabolismo en ratas .
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
Asesor: Joseph-Bravo, Patricia
10 - Rebolledo Solleiro, Daniela (2006). Estudio del efecto del estres agudo en el metabolismo del neuropeptido TRH (Hormona Liberadora de Tirotropina) en el sistema limbico.
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
Asesor: Joseph-Bravo, Patricia
11 - Garcia Vazquez, Arlene Iskra (2006). El estres psicologico modula la actividad de las neuronas TRHergicas en el sistema limbico.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Joseph-Bravo, Patricia
12 - Aguilar Valles, Argel (2005). Activacion de la sneuronas TRHergicas en hipocampo de ratas entrenadas en el laberinto de Morris .
Instituto de Biotecnologia,
Maestria en Ciencias (Bioquimica),
UNAM.
Asesor: Joseph-Bravo, Patricia
13 - Gortari Gallardo, Patricia Bertna Judith (2003). Regulacion de ectopeptidasas en el sistema nerviosos central.
Instituto de Neurobiologia,
Doctorado en Ciencias Fisiologicas,
UNAM.
Asesor: Joseph-Bravo, Patricia
14 - Torres Guerrero, Haydee K. (2002). Estudio sobre la inactivacion del TRH en terminales nerviosas.
Instituto de Investigaciones Biomedicas,
UNAM.
15 - Sanchez Jaramillo, Edith (2002). Heterogeneidad molecular y fisiologica de las neuronas trhergicas del nucleo para ventricular del hipotalamo de la rata .
Instituto de Biotecnologia,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Joseph-Bravo, Patricia
16 - Carreon Rodriguez, Alfonso (2000). Interaccion de activadores de proteinas cinasas A y C, glucocorticoides y hormonas tiroideas en la regulacion de la biosintesis rapida de la hormona liberadora de tirotropinaen cultivos primarios de celulas hipotalamicas fetales de rata.
Instituto de Biotecnologia,
Maestria en Ciencias (Bioquimica),
IBT,
UNAM.
Asesor: Joseph-Bravo, Patricia, Perez-Martinez,L.
17 - de Gortari Gallardo, Patricia Bertha Judith (1994). Cambios en la actividad de la enzima piroglutamato aminopeptidasa II provocados por el estimulo electrico en el sistema nervioso central .
Instituto de Biotecnologia,
Maestria en Biotecnologia,
UNAM.
Asesor: Joseph-Bravo, Patricia
18 - Ponce Romero, Georgina (1991). Algunos aspectos del control de la actividad hipofisaria .
Centro de Investigacion sobre Ingenieria Genetica y Biotecnologia,
Doctora en Investigacion Biomedica Basica,
UNAM.
Asesor: Joseph-Bravo, Patricia
19 - Cruz Fuentes, Carlos Sabas (1991). Estudio sobre el metabolismo de la neurona TRHergica .
Doctorado en Investigacion Biomedica Basica,
UNAM.
Asesor: Joseph-Bravo, Patricia
20 - Covarrubias Robles, Maria de Lourdes (1991). Regulacion de la biosintesis de TRH en cultivos de celulas dispersas de hipotalamo de rata.
Instituto de Biotecnologia,
Maestria en Investigacion Biomedica Basica,
UNAM.
Asesor: Joseph-Bravo, Patricia
21 - Covarrubias Robles, Luis Fernando (1989). Importancia del estudio a nivel molecular para la comprension del funcionamiento celular en eucariotes superiores regulacion de la actividad celular TRT-ERGICA .
Doctorado en Investigacion Biomedica Basica,
UNAM.
Asesor: Joseph-Bravo, Patricia
22 - Covarrubias Robles, Luis Fernando (1989). Importancia del estudio a nivel molecular para la comprension del funcionamiento celular en eucariotes superiores regulacion de la actividad celular TRTERGICA .
Instituto de Biotecnologia,
Doctorado en Investigacion Biomedica Basica,
UNAM.
Asesor: Joseph-Bravo, Patricia
23 - Baez Saldana, Armida (1989). Vias catabolicas extracelulares del neuropeptido TRH (Hormona libertadora de tirotropina) en el hipotalamo de la rata.
Facultad de Ciencias Quimicas,
Maestro en Ciencias Quimicas (Bioquimica),
UNAM.
24 - Guerra Nava, Cesar Eduardo (1987). Cultivo de celulas nerviosas de raton .
Licenciatura en Investigacion Biomedica Basica,
UNAM.
25 - Mendez Ubach, Milagros (1986). Propiedades que definen al TRH extrahipotalamico como posible neuromodulador en el sistema nervioso de rata.
Centro de Investigacion sobre Ingenieria Genetica y Biotecnologia,
Maestria en Ciencias Quimicas (Bioquimica),
UNAM.
Asesor: Joseph-Bravo, Patricia
26 - Saavedra Duran, Rafael Simitrio (1985). Obtencion y caracterizacion de aticuerpos monoclonales contra el factor liberador de la hormona lutienizante (LHRH).
Facultad de Quimica,
Quimico Farmaceutico Biologo,
UNAM.
27 - Garat, Beatriz (1984). Caracterizacion de una enzima membranal involucrada en la degradacion de la hormona liberadora de la tirotropia (TRH) en cerebro de rata .
Instituto de Investigaciones Biomedicas,
Maestro en Investigacion Biomedica Basica,
UNAM.
28 - Cohen Cory, Susana (1984). Caracterizacion del precursor biosintetico del factor liberador de la hormona luteinizante (LHRH).
Facultad de Quimica,
Quimico Farmaceutico Biologo,
UNAM.
29 - Redondo Meda, Jose Luis (1983). Cultivo de celulas dispersas de hipotalamo de raton .
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
Total de publicaciones: 128
- Tipo
- Fecha
in press
30 - Castillo-Campos,A., Gutierrez-Mata,A., Charli,J.L., Joseph-Bravo,P. (2020). Chronic stress inhibits hypothalamus-pituitary-thyroid axis and brown adipose tissue responses to acute cold exposure in male rats.
Journal of Endocrinological Investigation,
30 July online first.
Revisión
31 - Charli,J.L., Rodriguez-Rodriguez,A., Hernandez-Ortega,K., Cote-Velez,A., Uribe,R.M., Jaimes-Hoy,L., Joseph-Bravo,P. (2020). The Thyrotropin-Releasing Hormone-Degrading Ectoenzyme, a Therapeutic Target?.
Frontiers in Pharmacology,
11,
640.
Artículo
32 - Farkas,E., Varga,E., Kovacs,B., Szilvasy-Szabo,A., Cote-Velez,A., Peterfi,Z., Matziari,M., Toth,M., Zelena,D., Mezriczky,Z., Kadar,A., Kovari,D., Watanabe,M., Kano,M., Mackie,K., Rozsa,B., Ruska,Y., Toth,B., Mate,Z., Erdelyi,F., Szabo,G., Gereben,B., Lechan,R.M., Charli,J.L., Joseph-Bravo,P., Fekete,C. (2020). A glial-neuronal circuit in the median eminence regulates thyrotropin-releasing hormone-release via the endocannabinoid system.
iScience,
23 (3),
100921.
Artículo
33 - Joseph-Bravo,P., Lazcano,I., Jaimes-Hoy,L., Gutierrez-Mariscal,M., Sanchez-Jaramillo,E., Uribe,R.M., Charli,J.L. (2020). Sexually dimorphic dynamics of thyroid axis activity during fasting in rats.
Frontiers in Bioscience, Landmark,
25 (7),
1305-1323.
in press Revisión
34 - Lazcano,I., Rodriguez-Rodriguez,A., Uribe,R.M., Orozco,A., Joseph-Bravo,P., Charli,J.L. (2020). Evolution of thyrotropin-releasing factor extracellular communication units.
General and Comparative Endocrinology,
Available online 8 October 2020,
113642.
Artículo
35 - Jaimes-Hoy,L., Romero,F., Charli,J.L., Joseph-Bravo,P. (2019). Sex Dimorphic Responses of the Hypothalamus-Pituitary-Thyroid Axis to Maternal Separation and Palatable Diet.
Frontiers in Endocrinology,
10,
445.
Artículo
36 - Parra-Montes de Oca, M. A., Gutierrez-Mariscal, M., Salmeron-Jimenez, M. F., Jaimes-Hoy, L., Charli, J. L., Joseph-Bravo, P. (2019). Voluntary Exercise-Induced Activation of Thyroid Axis and Reduction of White Fat Depots Is Attenuated by Chronic Stress in a Sex Dimorphic Pattern in Adult Rats.
Frontiers in Endocrinology,
10,
418.
Revisión
37 - Rodriguez-Rodriguez, A., Lazcano, I., Sanchez-Jaramillo, E., Uribe, R. M., Jaimes-Hoy, L., Joseph-Bravo, P., Charli, J. L. (2019). Tanycytes and the Control of Thyrotropin-Releasing Hormone Flux Into Portal Capillaries.
Frontiers in Endocrinology,
10,
401.
Artículo
38 - Cote-Velez, A., Martinez-Baez A., Lezama, L., Uribe, R.M., Joseph-Bravo, P., Charli, J.L. (2017). A screen for modulators reveals that orexin-A rapidly stimulates thyrotropin releasing hormone expression and release in hypothalamic cell culture.
Neuropeptides,
62,
11-20.
Artículo
39 - Gonzalez-Franco, D.A., Ramirez-Amaya, V., Joseph-Bravo, P., Prado-Alcala, R.A., Quirarte, G.L. (2017). Differential Arc protein expression in dorsal and ventral striatum after moderate and intense inhibitory avoidance training.
Neurobiology of Learning and Memory,
140,
17-26.
Artículo
40 - Jaimes-Hoy, L., Gurrola, G.B., Cisneros, M., Joseph-Bravo, P., Possani, L.D., Charli, J.L. (2017). The Kv1.3 channel blocker Vm24 enhances muscle glucose transporter 4 mobilization but does not reduce body-weight gain in diet-induced obese male rats.
Life Sciences,
181,
23-30.
Artículo
41 - Sotelo-Rivera, I., Cote-Velez, A., Uribe, R.M., Charli, J.L., Joseph-Bravo, P. (2017). Glucocorticoids curtail stimuli-induced CREB phosphorylation in TRH neurons through interaction of the glucocorticoid receptor with the catalytic subunit of protein kinase A.
Endocrine,
55 (3),
861-871.
Artículo
42 - Jaimes-Hoy,L., Gutierrez-Mariscal,M., Vargas,Y., Perez-Maldonado,A., Romero,F., Sanchez-Jaramillo,E., Charli,J.L., Joseph-Bravo,P. (2016). Neonatal maternal separation alters, in a sex specific manner, the expression of TRH, of TRH-degrading ectoenzyme in the rat hypothalamus, and the response of the thyroid axis to starvation.
Endocrinology,
157 (8),
3253-3265.
Revisión
43 - Joseph-Bravo,P., Jaimes-Hoy,L., Charli,J.L. (2016). Advances in TRH signaling.
Reviews in Endocrine and Metabolic Disorders,
17 (4),
545-558.
Revisión
44 - Joseph-Bravo,P., Jaimes-Hoy,L., Charli,J. (2015). Regulation of TRH neurons and energy homeostasis related signals under stress.
Journal of Endocrinology,
224 (3),
R139-R159 [erratum en vol 227 (3) X1].
Revisión
45 - Joseph-Bravo,P., Jaimes-Hoy,L., Uribe,R.M., Charli,J.L. (2015). TRH, first hypophysiotropic releasing hormone isolated: its control of pituitary-thyroid axis.
Journal of Endocrinology,
226 (2),
T85-T100 [erratum en vol 227 (3) X3].
Artículo
46 - Lazcano,I., Cabral,A., Uribe,R.M., Jaimes-Hoy,L., Perello,M., Joseph-Bravo,P., Sanchez-Jaramillo,E., Charli,J.L. (2015). Fasting enhances pyroglutamyl peptidase II activity in tanycytes of the mediobasal hypothalamus of male adult rats.
Endocrinology,
156 (7),
2713-2723.
Artículo
47 - Rodriguez-Molina,V., Patino,J., Vargas,Y., Sanchez-Jaramillo,E., Joseph-Bravo,P., Charli,J.L. (2014). TRH regulates action potential shape in cerebral cortex pyramidal neurons.
Brain Research,
1571,
1-11.
Artículo
48 - Sotelo-Rivera,I., Jaimes-Hoy,L., Cote-Velez,A., Espinoza-Ayala,C., Charli,J.L., Joseph-Bravo,P. (2014). An acute injection of corticosterone increases thyrotrophin releasing hormone expression in the paraventricular nucleus of the hypothalamus but interferes with the rapid hypothalamus pituitary thyroid axis response to cold in male rats.
Journal of Neuroendocrinology,
26 (12),
861-869.
Artículo
49 - Uribe,R.M., Jaimes-Hoy,L., Ramirez-Martinez,C., Garcia-Vazquez,A., Romero,F., Cisneros,M., Cote-Velez,A., Charli,J.L., Joseph-Bravo,P. (2014). Voluntary exercise adapts the hypothalamus-pituitary-thyroid axis in male rats.
Endocrinology,
155 (5),
en20131724.
Artículo
50 - Gutierrez-Mariscal,M., Sanchez,E., Rebolledo-Solleiro,D., Garcia-Vazquez,A.I., Cote-Velez,A., Acasuso-Rivero,C., Charli,J.L., Joseph-Bravo,P. (2012). The acute response of the amygdalar TRH system to psychogenic stressors varies dependent on the paradigm and circadian condition.
Brain Research,
1452,
73-84.
Artículo
51 - Gutierrez-Mariscal,M., Sanchez,E., Garcia-Vazquez,A., Rebolledo-Solleiro,D., Charli,J.L., Joseph-Bravo,P. (2012). Acute response of hypophysiotropic thyrotropin releasing hormone neurons and thyrotropin release to behavioural paradigms producing varying intensities of stress and physical activity.
Regulatory Peptides,
179 (1-3),
61-70.
Artículo
52 - Lazcano,I., Uribe,R.M., Martinez-Chavez,Erick, Vargas,M.A., Matziari,M., Joseph-Bravo,P., Charli,J.L. (2012). Pyroglutamyl peptidase II inhibition enhances the analeptic effect of thyrotropin releasing hormone in the rat medial septum.
Journal of Pharmacology and Experimental Therapeutics,
342 (1),
222-231.
Artículo
53 - Cote-Velez,A., Perez-Maldonado,A., Osuna,J., Barrera,B., Charli,J.L., Joseph-Bravo,P. (2011). Creb and Sp/Kruppel response elements cooperate to control rat TRH gene transcription in response to cAMP.
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms,
1809 (3),
191-199.
Artículo
54 - Guerra-Crespo,M., Perez-Monter,C., Janga,S.C., Castillo-Ramirez,S., Gutierrez-Rios,R.M., Joseph-Bravo,P., Perez-Martinez,L., Charli,J.L. (2011). Transcriptional profiling of fetal hypothalamic TRH neurons.
BMC Genomics,
12 (1),
222.
Artículo
55 - Uribe,R.M., Cisneros,M., Vargas,M.A., Lezama,L., Cote-Velez,A., Joseph-Bravo,P., Charli,J.L. (2011). The systemic inhibition of nitric oxide production rapidly regulates TRH mRNA concentration in the paraventricular nucleus of the hypothalamus and serum TSH concentration. Studies in control and cold-stressed rats.
Brain Research,
1367,
188-197.
Artículo
56 - Diaz-Gallardo,M.Y., Cote-Velez,A., Charli,J.L., Joseph-Bravo,P. (2010). A rapid interference between glucocorticoids and cAMP-activated signaling in hypothalamic neurons prevents binding of pCREB and GR at the CRE-like and composite GRE sites of TRH gene promoter.
Journal of Neuroendocrinology,
22 (4),
282-293.
Artículo; Actas Paper
57 - Diaz-Gallardo,M.Y., Cote-Velez,A., Carreon-Rodriguez,A., Charli,J.L., Joseph-Bravo,P. (2010). Phosphorylated Cyclic-AMP-Response Element-Binding Protein and Thyroid Hormone Receptor Have Independent Response Elements in the Rat Thyrotropin-Releasing Hormone Promoter: An Analysis in Hypothalamic Cells.
Neuroendocrinology,
91 (1),
64-76.
Artículo
58 - de Gortari,P., Mancera,K., Cote-Velez,A., Amaya,M.I., Martinez,A., Jaimes-Hoy,L., Joseph-Bravo,P. (2009). Involvement of CRH-R2 receptor in eating behavior and in the response of the HPT axis in rats subjected to dehydration-induced anorexia.
Psychoneuroendocrinology,
34 (2),
259-272.
Artículo
59 - Rodriguez-Molina,V., Vargas,M.A., Joseph-Bravo,P., Charli,J.L. (2009). NMDA receptor up-regulates pyroglutamyl peptidase II activity in the rat hippocampus.
Neuroscience Letters,
449 (3),
211-214.
Artículo
60 - Uribe,R.M., Zacarias,M., Corkidi,G., Cisneros,M., Charli,J.L., Joseph-Bravo,P. (2009). 17beta-oestradiol indirectly inhibits trh expression in the hypothalamic paraventricular nucleus of female rats and blunts thyroid axis response to cold exposure.
Journal of Neuroendocrinology,
21 (5),
439-448.
Artículo
61 - Cote-Velez,A., Perez-Martinez,L., Charli,J.L., Joseph-Bravo,P. (2008). The PKC and ERK/MAPK Pathways Regulate Glucocorticoid Action on TRH Transcription.
Neurochemical Research,
33 (8),
1582-1591.
Artículo
62 - Cruz,R., Vargas,M.A., Uribe,R.M., Pascual,I., Lazcano,I., Yiotakis,A., Matziari,M., Joseph-Bravo,P., Charli,J.L. (2008). Anterior pituitary pyroglutamyl peptidase II activity controls TRH-induced prolactin release.
Peptides,
29 (11),
1953-1964.
Revisión
63 - Gutierrez-Mariscal,M., de Gortari,P., Lopez-Rubalcava,C., Martinez,A., Joseph-Bravo,P. (2008). Analysis of the anxiolytic-like effect of TRH and the response of amygdalar TRHergic neurons in anxiety.
Psychoneuroendocrinology,
33 (2),
198-213.
Artículo
64 - Jaimes-Hoy,L., Joseph-Bravo,P., de Gortari,P. (2008). Differential response of TRHergic neurons of the hypothalamic paraventricular nucleus (PVN) in female animals submitted to food-restriction or dehydration-induced anorexia and cold exposure.
Hormones and Behavior,
53 (2),
366-377.
Revisión
65 - Aguilar-Valles,A., Sanchez,E., de Gortari,P., Garcia-Vazquez,A.I., Ramirez-Amaya,V., Bermudez-Rattoni,F., Joseph-Bravo,P. (2007). The expression of TRH, its receptors and degrading enzyme is differentially modulated in the rat limbic system during training in the Morris water maze.
Neurochemistry International,
50 (2),
404-417.
Artículo
66 - de Gortari,P., Vargas,M.A., Martinez,A., Garcia-Vazquez,A.I., Uribe,R.M., Chavez-Gutierrez,L., Magdaleno,V., Boileau,G., Charli,J.L., Joseph-Bravo,P. (2007). Stage-specific Modulation of Neprilysin and Aminopeptidase N in the Limbic System During Kindling Progression.
Journal of Molecular Neuroscience,
33 (3),
252-261.
Artículo
67 - Sanchez,E., Fekete,C., Lechan,R.M., Joseph-Bravo,P. (2007). Cocaine- and amphetamine-regulated transcript (CART) expression is differentially regulated in the hypothalamic paraventricular nucleus of lactating rats exposed to suckling or cold stimulation.
Brain Research,
1132 (1),
120-128.
Artículo
68 - Ubieta,R., Uribe,R.M., Gonzalez,J.A., Garcia-Vazquez,A., Perez-Monter,C., Perez-Martinez,L., Joseph-Bravo,P., Charli,J.L. (2007). BDNF up-regulates pre-pro-TRH mRNA expression in the fetal/neonatal paraventricular nucleus of the hypothalamus. Properties of the transduction pathway.
Brain Research,
1174,
28-38.
Artículo
69 - Chavez-Gutierrez,L., Matta-Camacho,E., Osuna,J., Horjales,E., Joseph-Bravo,P., Maigret,B., Charli,J.L. (2006). Homology modeling and site directed mutagenesis of pyroglutamyl peptidase II. Insights into omega versus aminopeptidase specificity in the M1 family.
Journal of Biological Chemistry,
281 (27),
18581-18590.
Artículo
70 - de Gortari,P., Uribe,R.M., Garcia-Vazquez,A., Aguilar-Valles,A., Martinez,A., Valdes,A., Charli,J.L., Fernandez-Guardiola,A., Joseph-Bravo,P. (2006). Amygdala kindling differentially regulates the expression of the elements involved in TRH transmission.
Neurochemistry International,
48 (1),
31-42.
Artículo
71 - Aguilar-Valles,A., Sanchez,E., de Gortari,P., Balderas,I., Ramirez-Amaya,V., Bermudez-Rattoni,F., Joseph-Bravo,P. (2005). Analysis of the Stress Response in Rats Trained in the Water-Maze: Differential Expression of Corticotropin-Releasing Hormone, CRH-R1, Glucocorticoid Receptors and Brain-Derived Neurotrophic Factor in Limbic Regions.
Neuroendocrinology,
82 (5-6),
306-319.
Artículo
72 - Chavez-Gutierrez,L., Bourdais,J., Aranda,G., Vargas,M.A., Matta-Camacho,E., Ducancel,F, Segovia,L., Joseph-Bravo,P., Charli,J.L. (2005). A truncated isoform of pyroglutamyl aminopeptidase II produced by exon extension has dominant-negative activity.
Journal of Neurochemistry,
92 (4),
807-817.
Artículo
73 - Cote-Velez,A., Perez-Martinez,L., Diaz-Gallardo,M.Y., Perez-Monter,C., Carreon,A., Charli,J.L., Joseph-Bravo,P. (2005). Dexamethasone repressed cAMP rapid upregulation of TRH gene transcription. Identification of a composite GRE and a CRE in TRH promoter.
Journal of Molecular Endocrinology,
34 (1),
177-197.
Artículo
74 - de Gortari,P., Romero,F., Cisneros,M., Joseph-Bravo,P. (2005). Acute administration of alcohol modulates pyroglutamyl amino peptidase II activity and mRNA levels in rat limbic regions.
Neurochemistry International,
46 (4),
347-356.
Artículo
75 - de Gortari,P., Cisneros,M., Joseph-Bravo,P. (2005). Chronic ethanol or glucose consumption alter TRH content and pyroglutamyl aminopeptidase II activity in rat limbic regions.
Regulatory Peptides,
127 (1-3),
141-150.
Artículo
76 - Cruz,R., Chavez-Gutierrez,L., Joseph-Bravo,P., Charli,J.L. (2004). 3,3',5'-Triiodo-L-Thyronine Reduces Efficiency of mRNA Knockdown by Antisense Oligodeoxynucleotides: A Study with Pyroglutamyl Aminopeptidase II in Adenohypophysis .
Oligonucleotides,
14 (3),
176-190.
Artículo
77 - Pascual,I., Cisneros,M., Lage,J., Diaz,J, Joseph-Bravo,P., Charli,J.L., Chavez,M.A. (2004). Isolation and purification of HcPI, a natural inhibitor of pyroglutamil aminopeptidase II (TRH-degrading ectoenzyme) from extracts of Hermodice carunculata (annelide: Polychaeta).
Revista Biologia,
18 (1),
38-49.
Artículo
78 - Pascual,I., Gil-Parrado,S., Cisneros,M., Joseph-Bravo,P., Diaz,J., Possani,L.D., Charli,J.L., Chavez,M. (2004). Purification of a specific inhibitor of pyroglutamyl aminopeptidase II from the marine annelide Hermodice carunculata. In vivo effects in rodent brain.
International Journal of Biochemistry and Cell Biology,
36 (1),
138-152.
Artículo
79 - de Gortari,P., Cisneros,M., Medellin,M.A., Joseph-Bravo,P. (2002). Chronic ingestion of ethanol or glucose solutions affects hypothalamic and limbic TRH metabolism in dams and their pups.
Neurochemistry International,
41 (4),
237-249.
Artículo
80 - Joseph-Bravo,P., Perez-Martinez,L., Lezama,L., Morales-Chapa,C., Charli,J.L. (2002). An improved method for the expression of TRH in serum-supplemented primary cultures of fetal hypothalamic cells.
Brain Research Protocols,
9 (2),
93-104.
Artículo
81 - Vargas,M.A., Uribe,R.M., Cisneros,M., Romero,F., Gonzalez,S., Joseph-Bravo,P., Charli,J.L. (2002). Thyrotropin-releasing hormone regulates the diurnal variation of pyroglutamyl aminopeptidase II activity in the male rat adenohypophysis.
European Journal of Endocrinology,
147 (3),
363-369.
Artículo
82 - Vargas,M.A., Cisneros,M., Joseph-Bravo,P., Charli,J.L. (2002). Thyrotropin-releasing hormone-induced down-regulation of pyroglutamyl aminopeptidase II activity involves L-type calcium channels and cam kinase activities in cultures of adenohypophyseal cells.
Journal of Neuroendocrinology,
14 (3),
184-193.
Artículo
83 - Baeza,M.A., Ponce,G., Joseph-Bravo,P., Charli,J.L. (2001). Rapid down regulation of pyroglutamyl peptidase II activity by arachidonic acid in primary cultures of adenohypophyseal cells.
Life Sciences,
68 (17),
2051-2060.
Artículo
84 - Guerra-Crespo,M., Ubieta,R., Joseph-Bravo,P., Charli,J.L., Perez-Martinez,L. (2001). BDNF increases the early expression of TRH mRNA in fetal TrkB+ hypothalamic neurons in primary culture.
European Journal of Neuroscience,
14 (3),
483-494.
Artículo
85 - Perez-Martinez,L., Charli,J., Joseph-Bravo,P. (2001). Development of pro-TRH gene expression in primary cultures of fetal hypothalamic cells.
Developmental Brain Research,
130 (1),
73-81.
Artículo
86 - Sanchez,E., Uribe,R.M., Corkidi,G., Zoeller,R.T., Cisneros,M., Zacarias,M., Morales-Chapa,C., Charli,J.L., Joseph-Bravo,P. (2001). Differential Responses of Thyrotropin-Releasing Hormone (TRH) Neurons to Cold Exposure or Suckling Indicate Functional Heterogeneity of the TRH System in the Paraventricular Nucleus of the Rat Hypothalamus.
Neuroendocrinology,
74 (6),
407-422.
Artículo
87 - Bourdais,J., Romero,F., Uriostegui,B., Cisneros,M., Joseph-Bravo,P., Charli,J.L. (2000). [3-Me-His(2)]-TRH combined with dopamine withdrawal rapidly and transiently increases pyroglutamyl aminopeptidase II activity in primary cultures of adenohypophyseal cells.
Neuropeptides,
34 (2),
83-88.
Artículo
88 - de Gortari,P., Gonzalez-Alzati,M.E., Cisneros,M., Joseph-Bravo,P. (2000). Effect of fasting on the content of thyrotropin-releasing hormone and its mRNA in the central nervous system and pyroglutamyl peptidase II activity in the anterior pituitary of post-weaned and adult rats.
Nutritional Neuroscience,
3 (4),
255-265.
Revisión
89 - de Gortari,P., Mendez,M., Rodriguez-Keller,I., Perez-Martinez,L., Joseph-Bravob,P. (2000). Acute ethanol administration induces changes in TRH and proenkephalin expression in hypothalamic and limbic regions of rat brain.
Neurochemistry International,
37 (5-6),
483-496.
Artículo
90 - Niquet,J., Perez-Martinez,L., Guerra,M., Grouselle,D., Joseph-Bravo,P., Charli,J. (2000). Extracellular matrix proteins increase the expression of pro-TRH and pro-protein convertase PC1 in fetal hypothalamic neurons in vitro.
Developmental Brain Research,
120 (1),
49-56.
Artículo
91 - Vargas,M.A., Cisneros,M., Joseph-Bravo,P., Charli,J.L. (2000). Regulation of adenohypophyseal pyroglutamyl aminopeptidase II activity by thyrotropin-releasing hormone and phorbol esters.
Endocrine,
13 (3),
267-272.
Artículo
92 - Mendez,M., Cisneros,M., Baez,A., Joseph-Bravo,P., Charli,J.L. (1999). Three TRH-like molecules are released from rat hypothalamus in vitro.
Neurochemical Research,
24 (7),
815-823.
Artículo
93 - Perez-Martinez,L., Uribe,R.M., Sanchez,E., Carreon-Rodriguez,A., Chavez,L., Zacarias,M., Joseph-Bravo,P., Charli,J.L. (1999). Regulation of TRH biosynthesis in the paraventricular nucleus of rodent hypothalamus.
Current topics in neurochemistry,
2,
79-88.
Artículo; Actas Paper
94 - Charli,J.L., Vargas,M.A., Cisneros,M., de Gortari,P., Baeza,M.A., Jasso,P., Bourdais,J., Perez,L., Uribe,R.M., Joseph-Bravo,P. (1998). TRH inactivation in the extracellular compartment: role of pyroglutamyl peptidase II.
Neurobiology (Bp.),
6 (1),
45-57.
Artículo
95 - de Gortari,P., Joseph-Bravo,P., Monroy-Ruiz,J., Martinez,A., Cisneros,M., Fernandez-Guardiola,A. (1998). Brain thyrotropin-releasing hormone content varies through amygdaloid kindling development according to afterdischarge frequency and propagation.
Epilepsia,
39 (8),
897-903.
Revisión
96 - Joseph-Bravo,P., Uribe,R.M., Vargas,M.A., Perez-Martinez,L., Zoeller,T., Charli,J.L. (1998). Multifactorial modulation of TRH metabolism.
Cellular & Molecular Neurobiology,
18 (2),
231-247.
Artículo
97 - Perez-Martinez,L., Carreon-Rodriguez,A., Gonzalez-Alzati,M.E., Morales,C., Charli,J.L., Joseph-Bravo,P. (1998). Dexamethasone rapidly regulates TRH mRNA levels in hypothalamic cell cultures: interaction with the cAMP pathway.
Neuroendocrinology,
68 (5),
345-354.
Artículo
98 - Vargas,M.A., Bourdais,J., Sanchez,S., Uriostegui,B., Moreno,E., Joseph-Bravo,P., Charli,J.L. (1998). Multiple hypothalamic factors regulate pyroglutamyl peptidase II in cultures of adenohypophyseal cells: role of the cAMP pathway.
Journal of Neuroendocrinology,
10 (3),
199-206.
Artículo
99 - Sanchez,E., Charli,J.L., Morales,C., Corkidi,G., Seidah,N.G., Joseph-Bravo,P., Uribe,R.M. (1997). Expression of the proprotein convertases PC1 and PC2 mRNAs in thyrotropin releasing hormone neurons of the rat paraventricular nucleus of hypothalamus.
Brain Research,
761 (1),
77-86.
Artículo
100 - de Gortari,P., Fernandez-Guardiola,A., Martinez,A., Cisneros,M., Joseph-Bravo,P. (1995). Changes in TRH and its degrading enzyme pyroglutamyl peptidase II, during the development of amygdaloid kindling.
Brain Research,
679 (1),
144-150.
Artículo
101 - Uribe,R.M., Joseph-Bravo,P., Charli,J.L. (1995). Pups removal enhances thyrotropin-releasing hormone mRNA in the hypothalamic paraventricular nucleus.
European Journal of Endocrinology,
133 (3),
354-360.
Artículo
102 - Uribe,R.M., Perez-Martinez,L., Covarrubias,M.D., Gomez,O., Covarrubias,L., Charli,J.L., Joseph-Bravo,P. (1995). Phorbol ester or cAMP enhance thyrotropin-releasing hormone mRNA in primary cultures of hypothalamic cells.
Neuroscience Letters,
201 (1),
41-44.
Artículo
103 - Covarrubias,L., Redondo,J.L., Vargas,M.A., Uribe,R.M., Mendez,M., Joseph-Bravo,P., Charli,J.L. (1994). In vitro TRH release from hypothalamus slices varies during the diurnal cycle.
Neurochemical Research,
19 (7),
845-850.
Carta
Artículo
105 - Joseph-Bravo,P., Fresan,M., Cisneros,M., Vargas,M.A., Charli,J.L. (1994). Pyroglutamyl peptidase II activity is not in the processes of bulbospinal TRHergic neurons.
Neuroscience Letters,
178 (2),
243-246.
Artículo
106 - Uribe,R.M., Joseph-Bravo,P., Ponce,G., Cisneros,M., Aceves,C., Charli,J.L. (1994). Influence of thyroid status on TRH metabolism in rat olfactory bulb.
Peptides,
15 (3),
435-439.
Artículo
107 - Vargas,M.A., Joseph-Bravo,P., Charli,J.L. (1994). Thyrotropin-releasing hormone downregulates pyroglutamyl peptidase II activity in adenohypophyseal cells.
Neuroendocrinology,
60 (3),
323-330.
Artículo
108 - Brakch,N., Boileau,G., Simonetti,M., Nault,C., Joseph-Bravo,P., Rholam,M., Cohen,P. (1993). Prosomatostatin processing in Neuro2A cells. Role of beta-turn structure in the vicinity of the Arg-Lys cleavage site.
European Journal of Biochemistry,
216 (1),
39-47.
*
Artículo
109 - Uribe,R.M., Redondo,J.L., Charli,J.L., Joseph-Bravo,P. (1993). Suckling and cold stress rapidly and transiently increase TRH mRNA in the paraventricular nucleus.
Neuroendocrinology,
58 (1),
140-145.
Artículo
110 - Vargas,M.A., Cisneros,M., Herrera,J., Joseph-Bravo,P., Charli,J.L. (1992). Regional distribution of pyroglutamyl peptidase II in rabbit brain, spinal cord, and organs.
Peptides,
13 (2),
255-260.
Artículo
111 - Cruz,C., Charli,J.L., Vargas,M.A., Joseph-Bravo,P. (1991). Neuronal localization of pyroglutamate aminopeptidase II in primary cultures of fetal mouse brain.
Journal of Neurochemistry,
56 (5),
1594-1601.
Artículo
112 - Lepage-Lezin,A., Joseph-Bravo,P., Devilliers,G., Benedetti,L., Launay,J.M., Gomez,S., Cohen,P. (1991). Prosomatostatin is processed in the Golgi apparatus of rat neural cells.
Journal of Biological Chemistry,
266 (3),
1679-1688.
*
Artículo
113 - Uribe,R.M., Joseph-Bravo,P., Pasten,J., Ponce,G., Mendez,M., Covarrubias,L., Charli,J.L. (1991). Some events of thyrotropin-releasing hormone metabolism are regulated in lactating and cycling rats.
Neuroendocrinology,
54 (5),
493-498.
Artículo
114 - Mendez,M., Cruz,C., Joseph-Bravo,P., Wilk,S., Charli,J.L. (1990). Evaluation of the role of prolyl endopeptidase and pyroglutamyl peptidase I in the metabolism of LHRH and TRH in brain.
Neuropeptides,
17 (2),
55-62.
Artículo
115 - Charli,J.L., Mendez,M., Vargas,M.A., Cisneros,M., Assai,M., Joseph-Bravo,P., Wilk,S. (1989). Pyroglutamyl peptidase II inhibition specifically increases recovery of TRH released from rat brain slices.
Neuropeptides,
14 (3),
191-196.
Artículo
116 - Charli,J.L., Cruz,C., Ponce,G., Vargas,M.A., Mendez,M., Cisneros,M., Pasten,J., Joseph-Bravo,P. (1989). Physiological relevance of pyroglutamate aminopeptidase II.
Annals of the New York Academy of Sciences,
553,
563-564.
Artículo
117 - Covarrubias,L., Uribe,R.M., Mendez,M., Charli,J.L., Joseph-Bravo,P. (1989). Hypothalamic TRH mRNA regulation under different physiological conditions.
Annals of the New York Academy of Sciences,
553,
476-478.
Artículo
118 - Charli,J.L., Cruz,C., Vargas,M., Joseph-Bravo,P. (1988). The narrow specificity pyroglutamate aminopeptidase degrading TRH in brain is an ectoenzyme.
Neurochemistry International,
13,
237-242.
Artículo
119 - Covarrubias,L., Uribe,R.M., Mendez,M., Charli,J.L., Joseph-Bravo,P. (1988). Neuronal TRH synthesis: developmental and circadian TRH mRNA levels.
Biochemical and Biophysical Research Communications,
151 (1),
615-622.
Artículo
120 - Charli,J.L., Mendez,M., Joseph-Bravo,P., Wilk,S. (1987). Specific inhibitors of pyroglutamyl peptidase I and prolyl endopeptidase do not change the in vitro release of TRH or its content in rodent brain.
Neuropeptides,
9 (4),
373-378.
Artículo
121 - Mendez,M., Joseph-Bravo,P., Cisneros,M., Vargas,M.A., Charli,J.L. (1987). Regional distribution of in vitro release of thyrotropin releasing hormone in rat brain.
Peptides,
8 (2),
291-298.
Artículo
122 - Saavedra,R., Bravo,P.J., Charli,J.L., Herion,P. (1987). Characterization of high affinity monoclonal antibodies against the luteinizing hormone-releasing hormone.
Hybridoma,
6 (6),
663-672.
Artículo
123 - Vargas,M., Mendez,M., Cisneros,M., Joseph-Bravo,P., Charli,J.L. (1987). Regional distribution of the membrane-bound pyroglutamate amino peptidase-degrading thyrotropin-releasing hormone in rat brain.
Neuroscience Letters,
79 (3),
311-314.
Artículo
124 - Cohen,S., Charli,J.L., Diaz de Leon,L., Millar,R.P., Arimura,A., Morrison,M.R., Joseph-Bravo,P. (1986). Attempts to immunoprecipitate the LHRH precursor synthesized in cell free systems.
Brain Research Bulletin,
16 (3),
309-314.
Artículo
125 - Torres,H., Charli,J.L., Vargas,M.A., Gonzalez-Noriega,A., Joseph-Bravo,P. (1986). Subcellular distribution of the enzymes degrading Thyrotropin releasing hormone and metabolites in rat brain.
Neurochemistry International,
9,
103-110.
Artículo
126 - Garat,B., Miranda,J., Charli,J.L., Joseph-Bravo,P. (1985). Presence of a membrane bound pyroglutamyl amino peptidase degrading thyrotropin releasing hormone in rat brain.
Neuropeptides,
6 (1),
27-40.
Artículo
127 - Charli,J.L., Ponce,G., McKelvy,J.F., Joseph-Bravo,P. (1984). Accumulation of thyrotropin releasing hormone by rat hypothalamic slices.
Journal of Neurochemistry,
42 (4),
981-986.
Artículo
128 - Pacheco,M.F., McKelvy,J.F., Woodward,D.J., Loudes,C., Joseph-Bravo,P., Krulich,L., Griffin,W.S. (1981). TRH in the rat cerebellum: I. Distribution and concentration.
Peptides,
2 (3),
277-282.
*
Artículo
129 - Joseph-Bravo,P., Charli,J.L., Sherman,T., Boyer,H., Bolivar,F., McKelvy,J.F. (1980). Identification of a putative hypothalamic mRNA coding for somatostatin and of its product in cell-free translation.
Biochemical and Biophysical Research Communications,
94 (3),
1004-1012.
*
Artículo
130 - Joseph-Bravo,P., Loudes,C., Charli,J.L., Kordon,C. (1979). Subcellular distribution of brain peptidases degrading luteinizing hormone releasing hormone (LHRH) and thyrotropin releasing hormone (TRH).
Brain Research,
166 (2),
321-329.
*
Artículo
131 - Joseph-Bravo,P., Charli,J.L., Palacios,J.M., Kordon,C. (1979). Effect of neurotransmitters on the in vitro release of immunoreactive thyrotropin-releasing hormone from rat mediobasal hypothalamus.
Endocrinology,
104 (3),
801-806.
*
Artículo
132 - Lin,C., Joseph-Bravo,P., Sherman,T., Chan,L., McKelvy,J.F. (1979). Cell-free synthesis of putative neurophysin precursors from rat and mouse hypothalamic poly (A)-RNA.
Biochemical and Biophysical Research Communications,
89 (3),
943-950.
*
Artículo
133 - Loudes,C., Joseph-Bravo,P., Leblanc,P., Kordon,C. (1978). Specific activity of LHRH and TRH degrading enzymes in various tissues of normal and castrated male rats.
Biochemical and Biophysical Research Communications,
83 (3),
921-926.
*
Artículo
134 - Joseph-Bravo,P.I., Findley,M., Newberne,P.M. (1976). Some interactions of light, riboflavin, and aflatoxin B1 in vivo and in vitro.
Journal of Toxicology and Environmental Health,
1 (3),
353-376.
*
Internacional
135 - Joseph-Bravo, P., Gutierrez-Mariscal, M., Jaimes-Hoy, L., Charli, J. L. (2019). Thyroid Axis and Energy Balance: Focus on Animals and Implications for Humankind. Handbook of Famine, Starvation, and Nutrient Deprivation: From Biology to Policy.
1099-1126,
Cham, Suiza: Springer.
Nacional
136 - de Gortari,P., Joseph-Bravo,P. (2010). Regulacion neuroendocrina del apetito. Obesidad. Un enfoque multidisciplinario .
57-71,
Pachuca.
Nacional
137 - Charli,J.L., Joseph-Bravo,P. (2008). El cerebro, la comunicación intercelular y los p?ptidos. Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 5.
53-64,
Mexico, D.F..
Nacional
138 - Joseph-Bravo,P., de Gortari,P. (2008). El estrés y sus efectos en el metabolismo y el aprendizaje. Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 6.
65-76,
Mexico, D.F..
Memoria in extenso
139 - Joseph-Bravo,P., Mariscal,M., Garcia,I., Jaimes-Hoy,L., Charli,J.L., de Gortari,P. (2007). Response of limbic TRH neurons depends on the stress paradigm. Endocrine Regulations. Int. Congress of Stress.
96-.
Internacional
140 - de Gortari,P., Joseph,P. (2006). Neuroendocrine Regulation of Energy Metabolism. Molecular Endocrinology.
65-86,
Kerala, India: Research Signpost.
Internacional
141 - Joseph-Bravo,P., Cote-Velez,A., Perez-Martinez,L. (2006). Integration of Neuroendocrine Signals that Regulate the Activity of Hypophysiotropic Peptides. Molecular Endocrinology.
1-24,
Kerala, India: Research Signpost.
Nacional
142 - Joseph-Bravo,P. (1995). Choques, transtornos y otras caídas. Stress, dolor y p?ptidos. Memoria del Curso Explorando el Cerebro.
35-37,
Mexico,D.F..
Memoria in extenso
143 - Charli,J.L., Garat,B., Martinez-Escalera,G., Ponce,G., Miranda,J., Joseph-Bravo,P. (1984). METABOLISM OF THYROTROPIN RELEASING HORMONE AND ITS POSSIBLE RELEVANCE TO PROLACTIN SECRETION. Prolactin Secretion: a Multidisciplinary Approach.
239-248,
Orlando: Academic Press.
Memoria in extenso
144 - Kordon,C., Enjalbert,A., Hery,M., Joseph-Bravo,P., Rotsztjen,W., Ruberg.M. (1979). Role of neurotransmitters in the control of adenohypophyseal secretion. Handbook of the hypothalamus.
253-306,
2,
New York.
*
Internacional
Nacional
146 - Carreon-Rodriguez,A., Perez-Martinez,L., Joseph-Bravo,P. (2008). La participación de las hormonas tiroideas en el desarrollo y función del sistema nervioso.
Facultad de Medicina. Revista Actualidades de Posgrado para el Médico General,
12 (5),
9-12.
Editorial Material
147 - Joseph-Bravo,P. (2004). Hypophysiotropic thyrotropin-releasing hormone neurons as transducers of energy homeostasis.
Endocrinology,
145 (11),
4813-4815.
Note
148 - Charli,J.L., Cruz,C., Redondo,J.L., Guerra,C., Joseph-Bravo,P. (1995). Homologous conditioned medium enhances expression of TRH in hypothalamic neurons in primary culture.
Developmental Brain Research,
89 (1),
155-160.
Note
149 - Mendez,M., Moran,J., Wilk,S., Joseph-Bravo,P., Charli,J.L. (1993). Assessment of the role of TRH in the release of [3H]-dopamine from rat nucleus accumbens-lateral septum slices.
Brain Research Bulletin,
31 (5),
621-625.
Note
150 - Vargas,M.A., Herrera,J., Uribe,R.M., Charli,J.L., Joseph-Bravo,P. (1992). Ontogenesis of pyroglutamyl peptidase II activity in rat brain, adenohypophysis and pancreas.
Developmental Brain Research,
66 (2),
251-256.
Note
151 - Fuchs,L.Y., Ovando,C., Joseph,P., Soberon,X., Charli,J.L. (1990). Repetitive DNA sequence from the crayfish Procambarus clarkii.
Nucleic Acids Research,
18 (6),
1650.
Note
152 - Ponce,G., Charli,J.L., Pasten,J.A., Aceves,C., Joseph-Bravo,P. (1988). Tissue-specific regulation of pyroglutamate aminopeptidase II activity by thyroid hormones.
Neuroendocrinology,
48 (2),
211-213.
Nacional
153 - Charli,J.L., Ponce,G., Torres,H., Garat,B., Barquin,N., Bravo,P.J. (1983). [Cellular biochemistry of hypophysiotropic peptides. II. Liberation, action and inactivation].
Boletin de estudios medicos y biologicos,
32 (7-8 Suppl 1),
243-252.
Nacional
154 - Joseph-Bravo,P., Theleen,M., de Gortari,P., Shapiro,E., Redondo,J.L., Briones,M., Merchant,H., Charli,J.L. (1983). [Biochemistry of hypophysiotropic peptides. I. Biosynthesis and its regulation].
Boletin de estudios medicos y biologicos,
32 (7-8 Suppl 1),
233-241.
Nacional
155 - Charli,J.L., Joseph-Bravo,P., Robert,M. (1980). Use of synthetic oligonucleotides for identification of messenger RNA for somatostatin.
Boletin de estudios medicos y biologicos,
31 (3-4),
220-221.
*
Note
156 - Charli,J.L., Joseph-Bravo,P., Palacios,J.M., Kordon,C. (1978). Histamine-induced release of thyrotropin releasing hormone from hypothalamic slices.
European Journal of Pharmacology,
52 (3-4),
401-403.
*
157 - Joseph-Bravo, Patricia (1972). Efecto de la melatonina sobre el metabolismo de aminas biogenicas en sistema nervioso central .
Facultad de Quimica,
Quimico,
UNAM.
in press
158 - Castillo-Campos,A., Gutierrez-Mata,A., Charli,J.L., Joseph-Bravo,P.. Chronic stress inhibits hypothalamus-pituitary-thyroid axis and brown adipose tissue responses to acute cold exposure in male rats.
Journal of Endocrinological Investigation,
30 July online first.
Revisión
159 - Charli,J.L., Rodriguez-Rodriguez,A., Hernandez-Ortega,K., Cote-Velez,A., Uribe,R.M., Jaimes-Hoy,L., Joseph-Bravo,P.. The Thyrotropin-Releasing Hormone-Degrading Ectoenzyme, a Therapeutic Target?.
Frontiers in Pharmacology,
11,
640.
Artículo
160 - Farkas,E., Varga,E., Kovacs,B., Szilvasy-Szabo,A., Cote-Velez,A., Peterfi,Z., Matziari,M., Toth,M., Zelena,D., Mezriczky,Z., Kadar,A., Kovari,D., Watanabe,M., Kano,M., Mackie,K., Rozsa,B., Ruska,Y., Toth,B., Mate,Z., Erdelyi,F., Szabo,G., Gereben,B., Lechan,R.M., Charli,J.L., Joseph-Bravo,P., Fekete,C.. A glial-neuronal circuit in the median eminence regulates thyrotropin-releasing hormone-release via the endocannabinoid system.
iScience,
23 (3),
100921.
Artículo
161 - Joseph-Bravo,P., Lazcano,I., Jaimes-Hoy,L., Gutierrez-Mariscal,M., Sanchez-Jaramillo,E., Uribe,R.M., Charli,J.L.. Sexually dimorphic dynamics of thyroid axis activity during fasting in rats.
Frontiers in Bioscience, Landmark,
25 (7),
1305-1323.
in press Revisión
162 - Lazcano,I., Rodriguez-Rodriguez,A., Uribe,R.M., Orozco,A., Joseph-Bravo,P., Charli,J.L.. Evolution of thyrotropin-releasing factor extracellular communication units.
General and Comparative Endocrinology,
Available online 8 October 2020,
113642.
Artículo
163 - Jaimes-Hoy,L., Romero,F., Charli,J.L., Joseph-Bravo,P.. Sex Dimorphic Responses of the Hypothalamus-Pituitary-Thyroid Axis to Maternal Separation and Palatable Diet.
Frontiers in Endocrinology,
10,
445.
Artículo
164 - Parra-Montes de Oca, M. A., Gutierrez-Mariscal, M., Salmeron-Jimenez, M. F., Jaimes-Hoy, L., Charli, J. L., Joseph-Bravo, P.. Voluntary Exercise-Induced Activation of Thyroid Axis and Reduction of White Fat Depots Is Attenuated by Chronic Stress in a Sex Dimorphic Pattern in Adult Rats.
Frontiers in Endocrinology,
10,
418.
Revisión
165 - Rodriguez-Rodriguez, A., Lazcano, I., Sanchez-Jaramillo, E., Uribe, R. M., Jaimes-Hoy, L., Joseph-Bravo, P., Charli, J. L.. Tanycytes and the Control of Thyrotropin-Releasing Hormone Flux Into Portal Capillaries.
Frontiers in Endocrinology,
10,
401.
Internacional
166 - Joseph-Bravo, P., Gutierrez-Mariscal, M., Jaimes-Hoy, L., Charli, J. L.. Thyroid Axis and Energy Balance: Focus on Animals and Implications for Humankind. Handbook of Famine, Starvation, and Nutrient Deprivation: From Biology to Policy.
1099-1126,
Cham, Suiza: Springer.
Artículo
167 - Cote-Velez, A., Martinez-Baez A., Lezama, L., Uribe, R.M., Joseph-Bravo, P., Charli, J.L.. A screen for modulators reveals that orexin-A rapidly stimulates thyrotropin releasing hormone expression and release in hypothalamic cell culture.
Neuropeptides,
62,
11-20.
Artículo
168 - Gonzalez-Franco, D.A., Ramirez-Amaya, V., Joseph-Bravo, P., Prado-Alcala, R.A., Quirarte, G.L.. Differential Arc protein expression in dorsal and ventral striatum after moderate and intense inhibitory avoidance training.
Neurobiology of Learning and Memory,
140,
17-26.
Artículo
169 - Jaimes-Hoy, L., Gurrola, G.B., Cisneros, M., Joseph-Bravo, P., Possani, L.D., Charli, J.L.. The Kv1.3 channel blocker Vm24 enhances muscle glucose transporter 4 mobilization but does not reduce body-weight gain in diet-induced obese male rats.
Life Sciences,
181,
23-30.
Artículo
Artículo
171 - Jaimes-Hoy,L., Gutierrez-Mariscal,M., Vargas,Y., Perez-Maldonado,A., Romero,F., Sanchez-Jaramillo,E., Charli,J.L., Joseph-Bravo,P.. Neonatal maternal separation alters, in a sex specific manner, the expression of TRH, of TRH-degrading ectoenzyme in the rat hypothalamus, and the response of the thyroid axis to starvation.
Endocrinology,
157 (8),
3253-3265.
Revisión
172 - Joseph-Bravo,P., Jaimes-Hoy,L., Charli,J.L.. Advances in TRH signaling.
Reviews in Endocrine and Metabolic Disorders,
17 (4),
545-558.
Revisión
173 - Joseph-Bravo,P., Jaimes-Hoy,L., Charli,J.. Regulation of TRH neurons and energy homeostasis related signals under stress.
Journal of Endocrinology,
224 (3),
R139-R159 [erratum en vol 227 (3) X1].
Revisión
174 - Joseph-Bravo,P., Jaimes-Hoy,L., Uribe,R.M., Charli,J.L.. TRH, first hypophysiotropic releasing hormone isolated: its control of pituitary-thyroid axis.
Journal of Endocrinology,
226 (2),
T85-T100 [erratum en vol 227 (3) X3].
Artículo
175 - Lazcano,I., Cabral,A., Uribe,R.M., Jaimes-Hoy,L., Perello,M., Joseph-Bravo,P., Sanchez-Jaramillo,E., Charli,J.L.. Fasting enhances pyroglutamyl peptidase II activity in tanycytes of the mediobasal hypothalamus of male adult rats.
Endocrinology,
156 (7),
2713-2723.
Artículo
176 - Rodriguez-Molina,V., Patino,J., Vargas,Y., Sanchez-Jaramillo,E., Joseph-Bravo,P., Charli,J.L.. TRH regulates action potential shape in cerebral cortex pyramidal neurons.
Brain Research,
1571,
1-11.
Artículo
177 - Sotelo-Rivera,I., Jaimes-Hoy,L., Cote-Velez,A., Espinoza-Ayala,C., Charli,J.L., Joseph-Bravo,P.. An acute injection of corticosterone increases thyrotrophin releasing hormone expression in the paraventricular nucleus of the hypothalamus but interferes with the rapid hypothalamus pituitary thyroid axis response to cold in male rats.
Journal of Neuroendocrinology,
26 (12),
861-869.
Artículo
178 - Uribe,R.M., Jaimes-Hoy,L., Ramirez-Martinez,C., Garcia-Vazquez,A., Romero,F., Cisneros,M., Cote-Velez,A., Charli,J.L., Joseph-Bravo,P.. Voluntary exercise adapts the hypothalamus-pituitary-thyroid axis in male rats.
Endocrinology,
155 (5),
en20131724.
Artículo
179 - Gutierrez-Mariscal,M., Sanchez,E., Rebolledo-Solleiro,D., Garcia-Vazquez,A.I., Cote-Velez,A., Acasuso-Rivero,C., Charli,J.L., Joseph-Bravo,P.. The acute response of the amygdalar TRH system to psychogenic stressors varies dependent on the paradigm and circadian condition.
Brain Research,
1452,
73-84.
Artículo
180 - Gutierrez-Mariscal,M., Sanchez,E., Garcia-Vazquez,A., Rebolledo-Solleiro,D., Charli,J.L., Joseph-Bravo,P.. Acute response of hypophysiotropic thyrotropin releasing hormone neurons and thyrotropin release to behavioural paradigms producing varying intensities of stress and physical activity.
Regulatory Peptides,
179 (1-3),
61-70.
Artículo
181 - Lazcano,I., Uribe,R.M., Martinez-Chavez,Erick, Vargas,M.A., Matziari,M., Joseph-Bravo,P., Charli,J.L.. Pyroglutamyl peptidase II inhibition enhances the analeptic effect of thyrotropin releasing hormone in the rat medial septum.
Journal of Pharmacology and Experimental Therapeutics,
342 (1),
222-231.
Artículo
182 - Cote-Velez,A., Perez-Maldonado,A., Osuna,J., Barrera,B., Charli,J.L., Joseph-Bravo,P.. Creb and Sp/Kruppel response elements cooperate to control rat TRH gene transcription in response to cAMP.
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms,
1809 (3),
191-199.
Artículo
183 - Guerra-Crespo,M., Perez-Monter,C., Janga,S.C., Castillo-Ramirez,S., Gutierrez-Rios,R.M., Joseph-Bravo,P., Perez-Martinez,L., Charli,J.L.. Transcriptional profiling of fetal hypothalamic TRH neurons.
BMC Genomics,
12 (1),
222.
Artículo
184 - Uribe,R.M., Cisneros,M., Vargas,M.A., Lezama,L., Cote-Velez,A., Joseph-Bravo,P., Charli,J.L.. The systemic inhibition of nitric oxide production rapidly regulates TRH mRNA concentration in the paraventricular nucleus of the hypothalamus and serum TSH concentration. Studies in control and cold-stressed rats.
Brain Research,
1367,
188-197.
Artículo
185 - Diaz-Gallardo,M.Y., Cote-Velez,A., Charli,J.L., Joseph-Bravo,P.. A rapid interference between glucocorticoids and cAMP-activated signaling in hypothalamic neurons prevents binding of pCREB and GR at the CRE-like and composite GRE sites of TRH gene promoter.
Journal of Neuroendocrinology,
22 (4),
282-293.
Artículo; Actas Paper
186 - Diaz-Gallardo,M.Y., Cote-Velez,A., Carreon-Rodriguez,A., Charli,J.L., Joseph-Bravo,P.. Phosphorylated Cyclic-AMP-Response Element-Binding Protein and Thyroid Hormone Receptor Have Independent Response Elements in the Rat Thyrotropin-Releasing Hormone Promoter: An Analysis in Hypothalamic Cells.
Neuroendocrinology,
91 (1),
64-76.
Nacional
187 - de Gortari,P., Joseph-Bravo,P.. Regulacion neuroendocrina del apetito. Obesidad. Un enfoque multidisciplinario .
57-71,
Pachuca.
Artículo
188 - de Gortari,P., Mancera,K., Cote-Velez,A., Amaya,M.I., Martinez,A., Jaimes-Hoy,L., Joseph-Bravo,P.. Involvement of CRH-R2 receptor in eating behavior and in the response of the HPT axis in rats subjected to dehydration-induced anorexia.
Psychoneuroendocrinology,
34 (2),
259-272.
Artículo
189 - Rodriguez-Molina,V., Vargas,M.A., Joseph-Bravo,P., Charli,J.L.. NMDA receptor up-regulates pyroglutamyl peptidase II activity in the rat hippocampus.
Neuroscience Letters,
449 (3),
211-214.
Artículo
190 - Uribe,R.M., Zacarias,M., Corkidi,G., Cisneros,M., Charli,J.L., Joseph-Bravo,P.. 17beta-oestradiol indirectly inhibits trh expression in the hypothalamic paraventricular nucleus of female rats and blunts thyroid axis response to cold exposure.
Journal of Neuroendocrinology,
21 (5),
439-448.
Artículo
191 - Cote-Velez,A., Perez-Martinez,L., Charli,J.L., Joseph-Bravo,P.. The PKC and ERK/MAPK Pathways Regulate Glucocorticoid Action on TRH Transcription.
Neurochemical Research,
33 (8),
1582-1591.
Artículo
192 - Cruz,R., Vargas,M.A., Uribe,R.M., Pascual,I., Lazcano,I., Yiotakis,A., Matziari,M., Joseph-Bravo,P., Charli,J.L.. Anterior pituitary pyroglutamyl peptidase II activity controls TRH-induced prolactin release.
Peptides,
29 (11),
1953-1964.
Revisión
193 - Gutierrez-Mariscal,M., de Gortari,P., Lopez-Rubalcava,C., Martinez,A., Joseph-Bravo,P.. Analysis of the anxiolytic-like effect of TRH and the response of amygdalar TRHergic neurons in anxiety.
Psychoneuroendocrinology,
33 (2),
198-213.
Artículo
194 - Jaimes-Hoy,L., Joseph-Bravo,P., de Gortari,P.. Differential response of TRHergic neurons of the hypothalamic paraventricular nucleus (PVN) in female animals submitted to food-restriction or dehydration-induced anorexia and cold exposure.
Hormones and Behavior,
53 (2),
366-377.
Nacional
195 - Charli,J.L., Joseph-Bravo,P.. El cerebro, la comunicación intercelular y los p?ptidos. Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 5.
53-64,
Mexico, D.F..
Nacional
196 - Joseph-Bravo,P., de Gortari,P.. El estrés y sus efectos en el metabolismo y el aprendizaje. Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 6.
65-76,
Mexico, D.F..
Nacional
197 - Carreon-Rodriguez,A., Perez-Martinez,L., Joseph-Bravo,P.. La participación de las hormonas tiroideas en el desarrollo y función del sistema nervioso.
Facultad de Medicina. Revista Actualidades de Posgrado para el Médico General,
12 (5),
9-12.
Revisión
198 - Aguilar-Valles,A., Sanchez,E., de Gortari,P., Garcia-Vazquez,A.I., Ramirez-Amaya,V., Bermudez-Rattoni,F., Joseph-Bravo,P.. The expression of TRH, its receptors and degrading enzyme is differentially modulated in the rat limbic system during training in the Morris water maze.
Neurochemistry International,
50 (2),
404-417.
Artículo
199 - de Gortari,P., Vargas,M.A., Martinez,A., Garcia-Vazquez,A.I., Uribe,R.M., Chavez-Gutierrez,L., Magdaleno,V., Boileau,G., Charli,J.L., Joseph-Bravo,P.. Stage-specific Modulation of Neprilysin and Aminopeptidase N in the Limbic System During Kindling Progression.
Journal of Molecular Neuroscience,
33 (3),
252-261.
Artículo
200 - Sanchez,E., Fekete,C., Lechan,R.M., Joseph-Bravo,P.. Cocaine- and amphetamine-regulated transcript (CART) expression is differentially regulated in the hypothalamic paraventricular nucleus of lactating rats exposed to suckling or cold stimulation.
Brain Research,
1132 (1),
120-128.
Artículo
201 - Ubieta,R., Uribe,R.M., Gonzalez,J.A., Garcia-Vazquez,A., Perez-Monter,C., Perez-Martinez,L., Joseph-Bravo,P., Charli,J.L.. BDNF up-regulates pre-pro-TRH mRNA expression in the fetal/neonatal paraventricular nucleus of the hypothalamus. Properties of the transduction pathway.
Brain Research,
1174,
28-38.
Memoria in extenso
202 - Joseph-Bravo,P., Mariscal,M., Garcia,I., Jaimes-Hoy,L., Charli,J.L., de Gortari,P.. Response of limbic TRH neurons depends on the stress paradigm. Endocrine Regulations. Int. Congress of Stress.
96-.
Artículo
203 - Chavez-Gutierrez,L., Matta-Camacho,E., Osuna,J., Horjales,E., Joseph-Bravo,P., Maigret,B., Charli,J.L.. Homology modeling and site directed mutagenesis of pyroglutamyl peptidase II. Insights into omega versus aminopeptidase specificity in the M1 family.
Journal of Biological Chemistry,
281 (27),
18581-18590.
Artículo
204 - de Gortari,P., Uribe,R.M., Garcia-Vazquez,A., Aguilar-Valles,A., Martinez,A., Valdes,A., Charli,J.L., Fernandez-Guardiola,A., Joseph-Bravo,P.. Amygdala kindling differentially regulates the expression of the elements involved in TRH transmission.
Neurochemistry International,
48 (1),
31-42.
Internacional
205 - de Gortari,P., Joseph,P.. Neuroendocrine Regulation of Energy Metabolism. Molecular Endocrinology.
65-86,
Kerala, India: Research Signpost.
Internacional
206 - Joseph-Bravo,P., Cote-Velez,A., Perez-Martinez,L.. Integration of Neuroendocrine Signals that Regulate the Activity of Hypophysiotropic Peptides. Molecular Endocrinology.
1-24,
Kerala, India: Research Signpost.
Internacional
Artículo
208 - Aguilar-Valles,A., Sanchez,E., de Gortari,P., Balderas,I., Ramirez-Amaya,V., Bermudez-Rattoni,F., Joseph-Bravo,P.. Analysis of the Stress Response in Rats Trained in the Water-Maze: Differential Expression of Corticotropin-Releasing Hormone, CRH-R1, Glucocorticoid Receptors and Brain-Derived Neurotrophic Factor in Limbic Regions.
Neuroendocrinology,
82 (5-6),
306-319.
Artículo
209 - Chavez-Gutierrez,L., Bourdais,J., Aranda,G., Vargas,M.A., Matta-Camacho,E., Ducancel,F, Segovia,L., Joseph-Bravo,P., Charli,J.L.. A truncated isoform of pyroglutamyl aminopeptidase II produced by exon extension has dominant-negative activity.
Journal of Neurochemistry,
92 (4),
807-817.
Artículo
210 - Cote-Velez,A., Perez-Martinez,L., Diaz-Gallardo,M.Y., Perez-Monter,C., Carreon,A., Charli,J.L., Joseph-Bravo,P.. Dexamethasone repressed cAMP rapid upregulation of TRH gene transcription. Identification of a composite GRE and a CRE in TRH promoter.
Journal of Molecular Endocrinology,
34 (1),
177-197.
Artículo
211 - de Gortari,P., Romero,F., Cisneros,M., Joseph-Bravo,P.. Acute administration of alcohol modulates pyroglutamyl amino peptidase II activity and mRNA levels in rat limbic regions.
Neurochemistry International,
46 (4),
347-356.
Artículo
212 - de Gortari,P., Cisneros,M., Joseph-Bravo,P.. Chronic ethanol or glucose consumption alter TRH content and pyroglutamyl aminopeptidase II activity in rat limbic regions.
Regulatory Peptides,
127 (1-3),
141-150.
Artículo
213 - Cruz,R., Chavez-Gutierrez,L., Joseph-Bravo,P., Charli,J.L.. 3,3',5'-Triiodo-L-Thyronine Reduces Efficiency of mRNA Knockdown by Antisense Oligodeoxynucleotides: A Study with Pyroglutamyl Aminopeptidase II in Adenohypophysis .
Oligonucleotides,
14 (3),
176-190.
Artículo
214 - Pascual,I., Cisneros,M., Lage,J., Diaz,J, Joseph-Bravo,P., Charli,J.L., Chavez,M.A.. Isolation and purification of HcPI, a natural inhibitor of pyroglutamil aminopeptidase II (TRH-degrading ectoenzyme) from extracts of Hermodice carunculata (annelide: Polychaeta).
Revista Biologia,
18 (1),
38-49.
Artículo
215 - Pascual,I., Gil-Parrado,S., Cisneros,M., Joseph-Bravo,P., Diaz,J., Possani,L.D., Charli,J.L., Chavez,M.. Purification of a specific inhibitor of pyroglutamyl aminopeptidase II from the marine annelide Hermodice carunculata. In vivo effects in rodent brain.
International Journal of Biochemistry and Cell Biology,
36 (1),
138-152.
Editorial Material
216 - Joseph-Bravo,P.. Hypophysiotropic thyrotropin-releasing hormone neurons as transducers of energy homeostasis.
Endocrinology,
145 (11),
4813-4815.
Artículo
217 - de Gortari,P., Cisneros,M., Medellin,M.A., Joseph-Bravo,P.. Chronic ingestion of ethanol or glucose solutions affects hypothalamic and limbic TRH metabolism in dams and their pups.
Neurochemistry International,
41 (4),
237-249.
Artículo
218 - Joseph-Bravo,P., Perez-Martinez,L., Lezama,L., Morales-Chapa,C., Charli,J.L.. An improved method for the expression of TRH in serum-supplemented primary cultures of fetal hypothalamic cells.
Brain Research Protocols,
9 (2),
93-104.
Artículo
219 - Vargas,M.A., Uribe,R.M., Cisneros,M., Romero,F., Gonzalez,S., Joseph-Bravo,P., Charli,J.L.. Thyrotropin-releasing hormone regulates the diurnal variation of pyroglutamyl aminopeptidase II activity in the male rat adenohypophysis.
European Journal of Endocrinology,
147 (3),
363-369.
Artículo
220 - Vargas,M.A., Cisneros,M., Joseph-Bravo,P., Charli,J.L.. Thyrotropin-releasing hormone-induced down-regulation of pyroglutamyl aminopeptidase II activity involves L-type calcium channels and cam kinase activities in cultures of adenohypophyseal cells.
Journal of Neuroendocrinology,
14 (3),
184-193.
Artículo
221 - Baeza,M.A., Ponce,G., Joseph-Bravo,P., Charli,J.L.. Rapid down regulation of pyroglutamyl peptidase II activity by arachidonic acid in primary cultures of adenohypophyseal cells.
Life Sciences,
68 (17),
2051-2060.
Artículo
222 - Guerra-Crespo,M., Ubieta,R., Joseph-Bravo,P., Charli,J.L., Perez-Martinez,L.. BDNF increases the early expression of TRH mRNA in fetal TrkB+ hypothalamic neurons in primary culture.
European Journal of Neuroscience,
14 (3),
483-494.
Artículo
223 - Perez-Martinez,L., Charli,J., Joseph-Bravo,P.. Development of pro-TRH gene expression in primary cultures of fetal hypothalamic cells.
Developmental Brain Research,
130 (1),
73-81.
Artículo
224 - Sanchez,E., Uribe,R.M., Corkidi,G., Zoeller,R.T., Cisneros,M., Zacarias,M., Morales-Chapa,C., Charli,J.L., Joseph-Bravo,P.. Differential Responses of Thyrotropin-Releasing Hormone (TRH) Neurons to Cold Exposure or Suckling Indicate Functional Heterogeneity of the TRH System in the Paraventricular Nucleus of the Rat Hypothalamus.
Neuroendocrinology,
74 (6),
407-422.
Artículo
225 - Bourdais,J., Romero,F., Uriostegui,B., Cisneros,M., Joseph-Bravo,P., Charli,J.L.. [3-Me-His(2)]-TRH combined with dopamine withdrawal rapidly and transiently increases pyroglutamyl aminopeptidase II activity in primary cultures of adenohypophyseal cells.
Neuropeptides,
34 (2),
83-88.
Artículo
226 - de Gortari,P., Gonzalez-Alzati,M.E., Cisneros,M., Joseph-Bravo,P.. Effect of fasting on the content of thyrotropin-releasing hormone and its mRNA in the central nervous system and pyroglutamyl peptidase II activity in the anterior pituitary of post-weaned and adult rats.
Nutritional Neuroscience,
3 (4),
255-265.
Revisión
227 - de Gortari,P., Mendez,M., Rodriguez-Keller,I., Perez-Martinez,L., Joseph-Bravob,P.. Acute ethanol administration induces changes in TRH and proenkephalin expression in hypothalamic and limbic regions of rat brain.
Neurochemistry International,
37 (5-6),
483-496.
Artículo
228 - Niquet,J., Perez-Martinez,L., Guerra,M., Grouselle,D., Joseph-Bravo,P., Charli,J.. Extracellular matrix proteins increase the expression of pro-TRH and pro-protein convertase PC1 in fetal hypothalamic neurons in vitro.
Developmental Brain Research,
120 (1),
49-56.
Artículo
229 - Vargas,M.A., Cisneros,M., Joseph-Bravo,P., Charli,J.L.. Regulation of adenohypophyseal pyroglutamyl aminopeptidase II activity by thyrotropin-releasing hormone and phorbol esters.
Endocrine,
13 (3),
267-272.
Artículo
230 - Mendez,M., Cisneros,M., Baez,A., Joseph-Bravo,P., Charli,J.L.. Three TRH-like molecules are released from rat hypothalamus in vitro.
Neurochemical Research,
24 (7),
815-823.
Artículo
231 - Perez-Martinez,L., Uribe,R.M., Sanchez,E., Carreon-Rodriguez,A., Chavez,L., Zacarias,M., Joseph-Bravo,P., Charli,J.L.. Regulation of TRH biosynthesis in the paraventricular nucleus of rodent hypothalamus.
Current topics in neurochemistry,
2,
79-88.
Artículo; Actas Paper
232 - Charli,J.L., Vargas,M.A., Cisneros,M., de Gortari,P., Baeza,M.A., Jasso,P., Bourdais,J., Perez,L., Uribe,R.M., Joseph-Bravo,P.. TRH inactivation in the extracellular compartment: role of pyroglutamyl peptidase II.
Neurobiology (Bp.),
6 (1),
45-57.
Artículo
233 - de Gortari,P., Joseph-Bravo,P., Monroy-Ruiz,J., Martinez,A., Cisneros,M., Fernandez-Guardiola,A.. Brain thyrotropin-releasing hormone content varies through amygdaloid kindling development according to afterdischarge frequency and propagation.
Epilepsia,
39 (8),
897-903.
Revisión
234 - Joseph-Bravo,P., Uribe,R.M., Vargas,M.A., Perez-Martinez,L., Zoeller,T., Charli,J.L.. Multifactorial modulation of TRH metabolism.
Cellular & Molecular Neurobiology,
18 (2),
231-247.
Artículo
235 - Perez-Martinez,L., Carreon-Rodriguez,A., Gonzalez-Alzati,M.E., Morales,C., Charli,J.L., Joseph-Bravo,P.. Dexamethasone rapidly regulates TRH mRNA levels in hypothalamic cell cultures: interaction with the cAMP pathway.
Neuroendocrinology,
68 (5),
345-354.
Artículo
236 - Vargas,M.A., Bourdais,J., Sanchez,S., Uriostegui,B., Moreno,E., Joseph-Bravo,P., Charli,J.L.. Multiple hypothalamic factors regulate pyroglutamyl peptidase II in cultures of adenohypophyseal cells: role of the cAMP pathway.
Journal of Neuroendocrinology,
10 (3),
199-206.
Artículo
237 - Sanchez,E., Charli,J.L., Morales,C., Corkidi,G., Seidah,N.G., Joseph-Bravo,P., Uribe,R.M.. Expression of the proprotein convertases PC1 and PC2 mRNAs in thyrotropin releasing hormone neurons of the rat paraventricular nucleus of hypothalamus.
Brain Research,
761 (1),
77-86.
Artículo
238 - de Gortari,P., Fernandez-Guardiola,A., Martinez,A., Cisneros,M., Joseph-Bravo,P.. Changes in TRH and its degrading enzyme pyroglutamyl peptidase II, during the development of amygdaloid kindling.
Brain Research,
679 (1),
144-150.
Artículo
239 - Uribe,R.M., Joseph-Bravo,P., Charli,J.L.. Pups removal enhances thyrotropin-releasing hormone mRNA in the hypothalamic paraventricular nucleus.
European Journal of Endocrinology,
133 (3),
354-360.
Artículo
240 - Uribe,R.M., Perez-Martinez,L., Covarrubias,M.D., Gomez,O., Covarrubias,L., Charli,J.L., Joseph-Bravo,P.. Phorbol ester or cAMP enhance thyrotropin-releasing hormone mRNA in primary cultures of hypothalamic cells.
Neuroscience Letters,
201 (1),
41-44.
Nacional
241 - Joseph-Bravo,P.. Choques, transtornos y otras caídas. Stress, dolor y p?ptidos. Memoria del Curso Explorando el Cerebro.
35-37,
Mexico,D.F..
Note
242 - Charli,J.L., Cruz,C., Redondo,J.L., Guerra,C., Joseph-Bravo,P.. Homologous conditioned medium enhances expression of TRH in hypothalamic neurons in primary culture.
Developmental Brain Research,
89 (1),
155-160.
Artículo
243 - Covarrubias,L., Redondo,J.L., Vargas,M.A., Uribe,R.M., Mendez,M., Joseph-Bravo,P., Charli,J.L.. In vitro TRH release from hypothalamus slices varies during the diurnal cycle.
Neurochemical Research,
19 (7),
845-850.
Carta
Artículo
245 - Joseph-Bravo,P., Fresan,M., Cisneros,M., Vargas,M.A., Charli,J.L.. Pyroglutamyl peptidase II activity is not in the processes of bulbospinal TRHergic neurons.
Neuroscience Letters,
178 (2),
243-246.
Artículo
246 - Uribe,R.M., Joseph-Bravo,P., Ponce,G., Cisneros,M., Aceves,C., Charli,J.L.. Influence of thyroid status on TRH metabolism in rat olfactory bulb.
Peptides,
15 (3),
435-439.
Artículo
247 - Vargas,M.A., Joseph-Bravo,P., Charli,J.L.. Thyrotropin-releasing hormone downregulates pyroglutamyl peptidase II activity in adenohypophyseal cells.
Neuroendocrinology,
60 (3),
323-330.
Artículo
248 - Brakch,N., Boileau,G., Simonetti,M., Nault,C., Joseph-Bravo,P., Rholam,M., Cohen,P.. Prosomatostatin processing in Neuro2A cells. Role of beta-turn structure in the vicinity of the Arg-Lys cleavage site.
European Journal of Biochemistry,
216 (1),
39-47.
*
Artículo
249 - Uribe,R.M., Redondo,J.L., Charli,J.L., Joseph-Bravo,P.. Suckling and cold stress rapidly and transiently increase TRH mRNA in the paraventricular nucleus.
Neuroendocrinology,
58 (1),
140-145.
Note
250 - Mendez,M., Moran,J., Wilk,S., Joseph-Bravo,P., Charli,J.L.. Assessment of the role of TRH in the release of [3H]-dopamine from rat nucleus accumbens-lateral septum slices.
Brain Research Bulletin,
31 (5),
621-625.
Artículo
251 - Vargas,M.A., Cisneros,M., Herrera,J., Joseph-Bravo,P., Charli,J.L.. Regional distribution of pyroglutamyl peptidase II in rabbit brain, spinal cord, and organs.
Peptides,
13 (2),
255-260.
Note
252 - Vargas,M.A., Herrera,J., Uribe,R.M., Charli,J.L., Joseph-Bravo,P.. Ontogenesis of pyroglutamyl peptidase II activity in rat brain, adenohypophysis and pancreas.
Developmental Brain Research,
66 (2),
251-256.
Artículo
253 - Cruz,C., Charli,J.L., Vargas,M.A., Joseph-Bravo,P.. Neuronal localization of pyroglutamate aminopeptidase II in primary cultures of fetal mouse brain.
Journal of Neurochemistry,
56 (5),
1594-1601.
Artículo
254 - Lepage-Lezin,A., Joseph-Bravo,P., Devilliers,G., Benedetti,L., Launay,J.M., Gomez,S., Cohen,P.. Prosomatostatin is processed in the Golgi apparatus of rat neural cells.
Journal of Biological Chemistry,
266 (3),
1679-1688.
*
Artículo
255 - Uribe,R.M., Joseph-Bravo,P., Pasten,J., Ponce,G., Mendez,M., Covarrubias,L., Charli,J.L.. Some events of thyrotropin-releasing hormone metabolism are regulated in lactating and cycling rats.
Neuroendocrinology,
54 (5),
493-498.
Artículo
256 - Mendez,M., Cruz,C., Joseph-Bravo,P., Wilk,S., Charli,J.L.. Evaluation of the role of prolyl endopeptidase and pyroglutamyl peptidase I in the metabolism of LHRH and TRH in brain.
Neuropeptides,
17 (2),
55-62.
Note
257 - Fuchs,L.Y., Ovando,C., Joseph,P., Soberon,X., Charli,J.L.. Repetitive DNA sequence from the crayfish Procambarus clarkii.
Nucleic Acids Research,
18 (6),
1650.
Artículo
258 - Charli,J.L., Mendez,M., Vargas,M.A., Cisneros,M., Assai,M., Joseph-Bravo,P., Wilk,S.. Pyroglutamyl peptidase II inhibition specifically increases recovery of TRH released from rat brain slices.
Neuropeptides,
14 (3),
191-196.
Artículo
259 - Charli,J.L., Cruz,C., Ponce,G., Vargas,M.A., Mendez,M., Cisneros,M., Pasten,J., Joseph-Bravo,P.. Physiological relevance of pyroglutamate aminopeptidase II.
Annals of the New York Academy of Sciences,
553,
563-564.
Artículo
260 - Covarrubias,L., Uribe,R.M., Mendez,M., Charli,J.L., Joseph-Bravo,P.. Hypothalamic TRH mRNA regulation under different physiological conditions.
Annals of the New York Academy of Sciences,
553,
476-478.
Artículo
261 - Charli,J.L., Cruz,C., Vargas,M., Joseph-Bravo,P.. The narrow specificity pyroglutamate aminopeptidase degrading TRH in brain is an ectoenzyme.
Neurochemistry International,
13,
237-242.
Artículo
262 - Covarrubias,L., Uribe,R.M., Mendez,M., Charli,J.L., Joseph-Bravo,P.. Neuronal TRH synthesis: developmental and circadian TRH mRNA levels.
Biochemical and Biophysical Research Communications,
151 (1),
615-622.
Note
263 - Ponce,G., Charli,J.L., Pasten,J.A., Aceves,C., Joseph-Bravo,P.. Tissue-specific regulation of pyroglutamate aminopeptidase II activity by thyroid hormones.
Neuroendocrinology,
48 (2),
211-213.
Artículo
264 - Charli,J.L., Mendez,M., Joseph-Bravo,P., Wilk,S.. Specific inhibitors of pyroglutamyl peptidase I and prolyl endopeptidase do not change the in vitro release of TRH or its content in rodent brain.
Neuropeptides,
9 (4),
373-378.
Artículo
265 - Mendez,M., Joseph-Bravo,P., Cisneros,M., Vargas,M.A., Charli,J.L.. Regional distribution of in vitro release of thyrotropin releasing hormone in rat brain.
Peptides,
8 (2),
291-298.
Artículo
266 - Saavedra,R., Bravo,P.J., Charli,J.L., Herion,P.. Characterization of high affinity monoclonal antibodies against the luteinizing hormone-releasing hormone.
Hybridoma,
6 (6),
663-672.
Artículo
267 - Vargas,M., Mendez,M., Cisneros,M., Joseph-Bravo,P., Charli,J.L.. Regional distribution of the membrane-bound pyroglutamate amino peptidase-degrading thyrotropin-releasing hormone in rat brain.
Neuroscience Letters,
79 (3),
311-314.
Artículo
268 - Cohen,S., Charli,J.L., Diaz de Leon,L., Millar,R.P., Arimura,A., Morrison,M.R., Joseph-Bravo,P.. Attempts to immunoprecipitate the LHRH precursor synthesized in cell free systems.
Brain Research Bulletin,
16 (3),
309-314.
Artículo
269 - Torres,H., Charli,J.L., Vargas,M.A., Gonzalez-Noriega,A., Joseph-Bravo,P.. Subcellular distribution of the enzymes degrading Thyrotropin releasing hormone and metabolites in rat brain.
Neurochemistry International,
9,
103-110.
Artículo
270 - Garat,B., Miranda,J., Charli,J.L., Joseph-Bravo,P.. Presence of a membrane bound pyroglutamyl amino peptidase degrading thyrotropin releasing hormone in rat brain.
Neuropeptides,
6 (1),
27-40.
Artículo
271 - Charli,J.L., Ponce,G., McKelvy,J.F., Joseph-Bravo,P.. Accumulation of thyrotropin releasing hormone by rat hypothalamic slices.
Journal of Neurochemistry,
42 (4),
981-986.
Memoria in extenso
272 - Charli,J.L., Garat,B., Martinez-Escalera,G., Ponce,G., Miranda,J., Joseph-Bravo,P.. METABOLISM OF THYROTROPIN RELEASING HORMONE AND ITS POSSIBLE RELEVANCE TO PROLACTIN SECRETION. Prolactin Secretion: a Multidisciplinary Approach.
239-248,
Orlando: Academic Press.
Nacional
273 - Charli,J.L., Ponce,G., Torres,H., Garat,B., Barquin,N., Bravo,P.J.. [Cellular biochemistry of hypophysiotropic peptides. II. Liberation, action and inactivation].
Boletin de estudios medicos y biologicos,
32 (7-8 Suppl 1),
243-252.
Nacional
274 - Joseph-Bravo,P., Theleen,M., de Gortari,P., Shapiro,E., Redondo,J.L., Briones,M., Merchant,H., Charli,J.L.. [Biochemistry of hypophysiotropic peptides. I. Biosynthesis and its regulation].
Boletin de estudios medicos y biologicos,
32 (7-8 Suppl 1),
233-241.
Artículo
275 - Pacheco,M.F., McKelvy,J.F., Woodward,D.J., Loudes,C., Joseph-Bravo,P., Krulich,L., Griffin,W.S.. TRH in the rat cerebellum: I. Distribution and concentration.
Peptides,
2 (3),
277-282.
*
Artículo
276 - Joseph-Bravo,P., Charli,J.L., Sherman,T., Boyer,H., Bolivar,F., McKelvy,J.F.. Identification of a putative hypothalamic mRNA coding for somatostatin and of its product in cell-free translation.
Biochemical and Biophysical Research Communications,
94 (3),
1004-1012.
*
Nacional
277 - Charli,J.L., Joseph-Bravo,P., Robert,M.. Use of synthetic oligonucleotides for identification of messenger RNA for somatostatin.
Boletin de estudios medicos y biologicos,
31 (3-4),
220-221.
*
Artículo
278 - Joseph-Bravo,P., Loudes,C., Charli,J.L., Kordon,C.. Subcellular distribution of brain peptidases degrading luteinizing hormone releasing hormone (LHRH) and thyrotropin releasing hormone (TRH).
Brain Research,
166 (2),
321-329.
*
Artículo
279 - Joseph-Bravo,P., Charli,J.L., Palacios,J.M., Kordon,C.. Effect of neurotransmitters on the in vitro release of immunoreactive thyrotropin-releasing hormone from rat mediobasal hypothalamus.
Endocrinology,
104 (3),
801-806.
*
Artículo
280 - Lin,C., Joseph-Bravo,P., Sherman,T., Chan,L., McKelvy,J.F.. Cell-free synthesis of putative neurophysin precursors from rat and mouse hypothalamic poly (A)-RNA.
Biochemical and Biophysical Research Communications,
89 (3),
943-950.
*
Memoria in extenso
281 - Kordon,C., Enjalbert,A., Hery,M., Joseph-Bravo,P., Rotsztjen,W., Ruberg.M.. Role of neurotransmitters in the control of adenohypophyseal secretion. Handbook of the hypothalamus.
253-306,
2,
New York.
*
Artículo
282 - Loudes,C., Joseph-Bravo,P., Leblanc,P., Kordon,C.. Specific activity of LHRH and TRH degrading enzymes in various tissues of normal and castrated male rats.
Biochemical and Biophysical Research Communications,
83 (3),
921-926.
*
Note
283 - Charli,J.L., Joseph-Bravo,P., Palacios,J.M., Kordon,C.. Histamine-induced release of thyrotropin releasing hormone from hypothalamic slices.
European Journal of Pharmacology,
52 (3-4),
401-403.
*
Artículo
284 - Joseph-Bravo,P.I., Findley,M., Newberne,P.M.. Some interactions of light, riboflavin, and aflatoxin B1 in vivo and in vitro.
Journal of Toxicology and Environmental Health,
1 (3),
353-376.
*
285 - Joseph-Bravo, Patricia. Efecto de la melatonina sobre el metabolismo de aminas biogenicas en sistema nervioso central .
Facultad de Quimica,
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UNAM.
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