Dra. Patricia Ileana Joseph Bravo
Investigador
Neurobiología Celular y Molecular
Número de registros: 18
- Activos
- Vencidos
- Caracterización del efecto del estrés crónico e intermitente, a largo plazo, sobre la respuesta del eje tiroideo y el metabolismo., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2019 - 2021
- Efecto del estrés durante adolescencia sobre la respuesta del eje hipotálamo-pituitaria-tiroides a retos metabólicos y su repercusión en la homeostasis energética del roedor adulto de ambos sexos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2018 - 2021
- Efecto del estrés crónico en la respuesta de las neuronas trhérgicas y el eje tiroideo ante retos de demanda energética, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2016 - 2019
- Aspectos moleculares y celulares de la comunicación peptidérgica en el sistema nervioso, PRESUPUESTO UNAM, 2014 - 2020
- Dinámica de los efectos de glucocorticoides en la respuesta de las neuronas trhérgicas hipofisiotrópicas y el eje tiroideo a estímulos de demanda energética, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2013 - 2016
- Efectos del estrés postnatal sobre la respuesta del eje hipotálamo-pituitaria-tiroides a retos metabólicos. búsqueda de cambios epigenéticos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2012 - 2016
- Efecto de glucocorticoides y hormonas tiroideas en la regulación neuronal de la transcripción del gen de trh, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2010 - 2012
- Cambios en la conducta de ansiedad y en la transformacion thrergica del sistema limbico en ratas sometidas a un estrés agudo, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2009
- Efecto del estrés sobre la actividad de las neuronas trhérgicas del sistema límbico, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2008 - 2011
- Respuesta de las neuronas trhérgicas del sistema límbico al estrés, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2007 - 2009
- Estudios sobre la función del trh en el sistema límbico, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2004 - 2007
- Estudio sobre la biosíntesis del trh en el eje neuroendócrino., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2004 - 2005
- El trh como neuromodulador en el sistema límbico., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2004 - 2005
- Efectos de los glucocorticoides sobre la expresión del protrh., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2003
- Regulación de la biosíntesis de trh en el núcleo paraventricular del hipotálamo (iii)., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2000 - 2003
- Regulación del metabolismo de trh en el sistema nervioso central (iv)., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2000 - 2003
- Regulación de la biosíntesis de trh en el núcleo paraventricular: vías y mecanismos de regulación (ii), CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1998 - 2001
- Regulación del metabolismo del trh en el sistema nervioso ii, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 1997 - 2000
Nivel D del PRIDE
Nivel III del SNI
Nivel III del SNI
Doctorado, en Bioquímica, Universidad de Londres, Colegio Imperial de Ciencia y Tecnología
Maestría, en Nutricion y Metabolismo. Mass. Inst. of Technology, Cambridge, Mass E.U.A. Dept. de Ciencia en Nutrición y Metabolismo (1974)
Licenciatura, Química, Fac. de Química-UNAM (1970)
Miembro del Consejo Consultivo de Posgrado de la UNAM, 2003
Distinción Juana Ramírez de Abaje, UNAM, 2003
Premio Miguel Aleman, 1988
-
Doctorado
-
Caracterización de los circuitos noradrenérgicos involucrados en la respuesta del eje HPT al frío
-
M.C. Marco Antonio Parra Montes de oca
El estrés durante la adolescencia de ratas modifica su respuesta a retos metabólicos. -
Cambios epigenéticos en el promotor de TRH en respuesta al estrés perinatal
-
Maestría
-
El estrés durante la adolescencia modifica la respuesta del eje tiroideo al ejercicio.
-
Licenciatura
Total de publicaciones: 129
- Tipo
- Fecha
Artículo
1 - Castillo-Campos,A., Gutierrez-Mata,A., Charli,J.L., Joseph-Bravo,P. (2021). Chronic stress inhibits hypothalamus-pituitary-thyroid axis and brown adipose tissue responses to acute cold exposure in male rats.
Journal of Endocrinological Investigation,
44,
713.
Artículo
2 - Jaimes-Hoy,L., Perez-Maldonado,A., Narvaez-Bahena,E., de la Cruz Guarneros,N., Rodriguez-Rodriguez,A., Charli,J.L., Soberon,X., Joseph-Bravo,P. (2021). Sex dimorphic changes in Trh gene methylation and thyroid-axis response to energy demands in maternally-separated rats.
Endocrinology,
May 27 Online ahead of print.
Revisión
3 - Lazcano,I., Rodriguez-Rodriguez,A., Uribe,R.M., Orozco,A., Joseph-Bravo,P., Charli,J.L. (2021). Evolution of thyrotropin-releasing factor extracellular communication units.
General and Comparative Endocrinology,
305,
113642.
Revisión
4 - Charli,J.L., Rodriguez-Rodriguez,A., Hernandez-Ortega,K., Cote-Velez,A., Uribe,R.M., Jaimes-Hoy,L., Joseph-Bravo,P. (2020). The Thyrotropin-Releasing Hormone-Degrading Ectoenzyme, a Therapeutic Target?.
Frontiers in Pharmacology,
11,
640.
Artículo
5 - Farkas,E., Varga,E., Kovacs,B., Szilvasy-Szabo,A., Cote-Velez,A., Peterfi,Z., Matziari,M., Toth,M., Zelena,D., Mezriczky,Z., Kadar,A., Kovari,D., Watanabe,M., Kano,M., Mackie,K., Rozsa,B., Ruska,Y., Toth,B., Mate,Z., Erdelyi,F., Szabo,G., Gereben,B., Lechan,R.M., Charli,J.L., Joseph-Bravo,P., Fekete,C. (2020). A glial-neuronal circuit in the median eminence regulates thyrotropin-releasing hormone-release via the endocannabinoid system.
iScience,
23 (3),
100921.
Artículo
6 - Joseph-Bravo,P., Lazcano,I., Jaimes-Hoy,L., Gutierrez-Mariscal,M., Sanchez-Jaramillo,E., Uribe,R.M., Charli,J.L. (2020). Sexually dimorphic dynamics of thyroid axis activity during fasting in rats.
Frontiers in Bioscience, Landmark,
25 (7),
1305-1323.
Artículo
7 - Jaimes-Hoy,L., Romero,F., Charli,J.L., Joseph-Bravo,P. (2019). Sex Dimorphic Responses of the Hypothalamus-Pituitary-Thyroid Axis to Maternal Separation and Palatable Diet.
Frontiers in Endocrinology,
10,
445.
Artículo
8 - Parra-Montes de Oca, M. A., Gutierrez-Mariscal, M., Salmeron-Jimenez, M. F., Jaimes-Hoy, L., Charli, J. L., Joseph-Bravo, P. (2019). Voluntary Exercise-Induced Activation of Thyroid Axis and Reduction of White Fat Depots Is Attenuated by Chronic Stress in a Sex Dimorphic Pattern in Adult Rats.
Frontiers in Endocrinology,
10,
418.
Revisión
9 - Rodriguez-Rodriguez, A., Lazcano, I., Sanchez-Jaramillo, E., Uribe, R. M., Jaimes-Hoy, L., Joseph-Bravo, P., Charli, J. L. (2019). Tanycytes and the Control of Thyrotropin-Releasing Hormone Flux Into Portal Capillaries.
Frontiers in Endocrinology,
10,
401.
Artículo
10 - Cote-Velez, A., Martinez-Baez A., Lezama, L., Uribe, R.M., Joseph-Bravo, P., Charli, J.L. (2017). A screen for modulators reveals that orexin-A rapidly stimulates thyrotropin releasing hormone expression and release in hypothalamic cell culture.
Neuropeptides,
62,
11-20.
Artículo
11 - Gonzalez-Franco, D.A., Ramirez-Amaya, V., Joseph-Bravo, P., Prado-Alcala, R.A., Quirarte, G.L. (2017). Differential Arc protein expression in dorsal and ventral striatum after moderate and intense inhibitory avoidance training.
Neurobiology of Learning and Memory,
140,
17-26.
Artículo
12 - Jaimes-Hoy, L., Gurrola, G.B., Cisneros, M., Joseph-Bravo, P., Possani, L.D., Charli, J.L. (2017). The Kv1.3 channel blocker Vm24 enhances muscle glucose transporter 4 mobilization but does not reduce body-weight gain in diet-induced obese male rats.
Life Sciences,
181,
23-30.
Artículo
13 - Sotelo-Rivera, I., Cote-Velez, A., Uribe, R.M., Charli, J.L., Joseph-Bravo, P. (2017). Glucocorticoids curtail stimuli-induced CREB phosphorylation in TRH neurons through interaction of the glucocorticoid receptor with the catalytic subunit of protein kinase A.
Endocrine,
55 (3),
861-871.
Artículo
14 - Jaimes-Hoy,L., Gutierrez-Mariscal,M., Vargas,Y., Perez-Maldonado,A., Romero,F., Sanchez-Jaramillo,E., Charli,J.L., Joseph-Bravo,P. (2016). Neonatal maternal separation alters, in a sex specific manner, the expression of TRH, of TRH-degrading ectoenzyme in the rat hypothalamus, and the response of the thyroid axis to starvation.
Endocrinology,
157 (8),
3253-3265.
Revisión
15 - Joseph-Bravo,P., Jaimes-Hoy,L., Charli,J.L. (2016). Advances in TRH signaling.
Reviews in Endocrine and Metabolic Disorders,
17 (4),
545-558.
Revisión
16 - Joseph-Bravo,P., Jaimes-Hoy,L., Charli,J. (2015). Regulation of TRH neurons and energy homeostasis related signals under stress.
Journal of Endocrinology,
224 (3),
R139-R159 [erratum en vol 227 (3) X1].
Revisión
17 - Joseph-Bravo,P., Jaimes-Hoy,L., Uribe,R.M., Charli,J.L. (2015). TRH, first hypophysiotropic releasing hormone isolated: its control of pituitary-thyroid axis.
Journal of Endocrinology,
226 (2),
T85-T100 [erratum en vol 227 (3) X3].
Artículo
18 - Lazcano,I., Cabral,A., Uribe,R.M., Jaimes-Hoy,L., Perello,M., Joseph-Bravo,P., Sanchez-Jaramillo,E., Charli,J.L. (2015). Fasting enhances pyroglutamyl peptidase II activity in tanycytes of the mediobasal hypothalamus of male adult rats.
Endocrinology,
156 (7),
2713-2723.
Artículo
19 - Rodriguez-Molina,V., Patino,J., Vargas,Y., Sanchez-Jaramillo,E., Joseph-Bravo,P., Charli,J.L. (2014). TRH regulates action potential shape in cerebral cortex pyramidal neurons.
Brain Research,
1571,
1-11.
Artículo
20 - Sotelo-Rivera,I., Jaimes-Hoy,L., Cote-Velez,A., Espinoza-Ayala,C., Charli,J.L., Joseph-Bravo,P. (2014). An acute injection of corticosterone increases thyrotrophin releasing hormone expression in the paraventricular nucleus of the hypothalamus but interferes with the rapid hypothalamus pituitary thyroid axis response to cold in male rats.
Journal of Neuroendocrinology,
26 (12),
861-869.
Artículo
21 - Uribe,R.M., Jaimes-Hoy,L., Ramirez-Martinez,C., Garcia-Vazquez,A., Romero,F., Cisneros,M., Cote-Velez,A., Charli,J.L., Joseph-Bravo,P. (2014). Voluntary exercise adapts the hypothalamus-pituitary-thyroid axis in male rats.
Endocrinology,
155 (5),
en20131724.
Artículo
22 - Gutierrez-Mariscal,M., Sanchez,E., Rebolledo-Solleiro,D., Garcia-Vazquez,A.I., Cote-Velez,A., Acasuso-Rivero,C., Charli,J.L., Joseph-Bravo,P. (2012). The acute response of the amygdalar TRH system to psychogenic stressors varies dependent on the paradigm and circadian condition.
Brain Research,
1452,
73-84.
Artículo
23 - Gutierrez-Mariscal,M., Sanchez,E., Garcia-Vazquez,A., Rebolledo-Solleiro,D., Charli,J.L., Joseph-Bravo,P. (2012). Acute response of hypophysiotropic thyrotropin releasing hormone neurons and thyrotropin release to behavioural paradigms producing varying intensities of stress and physical activity.
Regulatory Peptides,
179 (1-3),
61-70.
Artículo
24 - Lazcano,I., Uribe,R.M., Martinez-Chavez,Erick, Vargas,M.A., Matziari,M., Joseph-Bravo,P., Charli,J.L. (2012). Pyroglutamyl peptidase II inhibition enhances the analeptic effect of thyrotropin releasing hormone in the rat medial septum.
Journal of Pharmacology and Experimental Therapeutics,
342 (1),
222-231.
Artículo
25 - Cote-Velez,A., Perez-Maldonado,A., Osuna,J., Barrera,B., Charli,J.L., Joseph-Bravo,P. (2011). Creb and Sp/Kruppel response elements cooperate to control rat TRH gene transcription in response to cAMP.
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms,
1809 (3),
191-199.
Artículo
26 - Guerra-Crespo,M., Perez-Monter,C., Janga,S.C., Castillo-Ramirez,S., Gutierrez-Rios,R.M., Joseph-Bravo,P., Perez-Martinez,L., Charli,J.L. (2011). Transcriptional profiling of fetal hypothalamic TRH neurons.
BMC Genomics,
12 (1),
222.
Artículo
27 - Uribe,R.M., Cisneros,M., Vargas,M.A., Lezama,L., Cote-Velez,A., Joseph-Bravo,P., Charli,J.L. (2011). The systemic inhibition of nitric oxide production rapidly regulates TRH mRNA concentration in the paraventricular nucleus of the hypothalamus and serum TSH concentration. Studies in control and cold-stressed rats.
Brain Research,
1367,
188-197.
Artículo
28 - Diaz-Gallardo,M.Y., Cote-Velez,A., Charli,J.L., Joseph-Bravo,P. (2010). A rapid interference between glucocorticoids and cAMP-activated signaling in hypothalamic neurons prevents binding of pCREB and GR at the CRE-like and composite GRE sites of TRH gene promoter.
Journal of Neuroendocrinology,
22 (4),
282-293.
Artículo; Actas Paper
29 - Diaz-Gallardo,M.Y., Cote-Velez,A., Carreon-Rodriguez,A., Charli,J.L., Joseph-Bravo,P. (2010). Phosphorylated Cyclic-AMP-Response Element-Binding Protein and Thyroid Hormone Receptor Have Independent Response Elements in the Rat Thyrotropin-Releasing Hormone Promoter: An Analysis in Hypothalamic Cells.
Neuroendocrinology,
91 (1),
64-76.
Artículo
30 - de Gortari,P., Mancera,K., Cote-Velez,A., Amaya,M.I., Martinez,A., Jaimes-Hoy,L., Joseph-Bravo,P. (2009). Involvement of CRH-R2 receptor in eating behavior and in the response of the HPT axis in rats subjected to dehydration-induced anorexia.
Psychoneuroendocrinology,
34 (2),
259-272.
Artículo
31 - Rodriguez-Molina,V., Vargas,M.A., Joseph-Bravo,P., Charli,J.L. (2009). NMDA receptor up-regulates pyroglutamyl peptidase II activity in the rat hippocampus.
Neuroscience Letters,
449 (3),
211-214.
Artículo
32 - Uribe,R.M., Zacarias,M., Corkidi,G., Cisneros,M., Charli,J.L., Joseph-Bravo,P. (2009). 17beta-oestradiol indirectly inhibits trh expression in the hypothalamic paraventricular nucleus of female rats and blunts thyroid axis response to cold exposure.
Journal of Neuroendocrinology,
21 (5),
439-448.
Artículo
33 - Cote-Velez,A., Perez-Martinez,L., Charli,J.L., Joseph-Bravo,P. (2008). The PKC and ERK/MAPK Pathways Regulate Glucocorticoid Action on TRH Transcription.
Neurochemical Research,
33 (8),
1582-1591.
Artículo
34 - Cruz,R., Vargas,M.A., Uribe,R.M., Pascual,I., Lazcano,I., Yiotakis,A., Matziari,M., Joseph-Bravo,P., Charli,J.L. (2008). Anterior pituitary pyroglutamyl peptidase II activity controls TRH-induced prolactin release.
Peptides,
29 (11),
1953-1964.
Revisión
35 - Gutierrez-Mariscal,M., de Gortari,P., Lopez-Rubalcava,C., Martinez,A., Joseph-Bravo,P. (2008). Analysis of the anxiolytic-like effect of TRH and the response of amygdalar TRHergic neurons in anxiety.
Psychoneuroendocrinology,
33 (2),
198-213.
Artículo
36 - Jaimes-Hoy,L., Joseph-Bravo,P., de Gortari,P. (2008). Differential response of TRHergic neurons of the hypothalamic paraventricular nucleus (PVN) in female animals submitted to food-restriction or dehydration-induced anorexia and cold exposure.
Hormones and Behavior,
53 (2),
366-377.
Revisión
37 - Aguilar-Valles,A., Sanchez,E., de Gortari,P., Garcia-Vazquez,A.I., Ramirez-Amaya,V., Bermudez-Rattoni,F., Joseph-Bravo,P. (2007). The expression of TRH, its receptors and degrading enzyme is differentially modulated in the rat limbic system during training in the Morris water maze.
Neurochemistry International,
50 (2),
404-417.
Artículo
38 - de Gortari,P., Vargas,M.A., Martinez,A., Garcia-Vazquez,A.I., Uribe,R.M., Chavez-Gutierrez,L., Magdaleno,V., Boileau,G., Charli,J.L., Joseph-Bravo,P. (2007). Stage-specific Modulation of Neprilysin and Aminopeptidase N in the Limbic System During Kindling Progression.
Journal of Molecular Neuroscience,
33 (3),
252-261.
Artículo
39 - Sanchez,E., Fekete,C., Lechan,R.M., Joseph-Bravo,P. (2007). Cocaine- and amphetamine-regulated transcript (CART) expression is differentially regulated in the hypothalamic paraventricular nucleus of lactating rats exposed to suckling or cold stimulation.
Brain Research,
1132 (1),
120-128.
Artículo
40 - Ubieta,R., Uribe,R.M., Gonzalez,J.A., Garcia-Vazquez,A., Perez-Monter,C., Perez-Martinez,L., Joseph-Bravo,P., Charli,J.L. (2007). BDNF up-regulates pre-pro-TRH mRNA expression in the fetal/neonatal paraventricular nucleus of the hypothalamus. Properties of the transduction pathway.
Brain Research,
1174,
28-38.
Artículo
41 - Chavez-Gutierrez,L., Matta-Camacho,E., Osuna,J., Horjales,E., Joseph-Bravo,P., Maigret,B., Charli,J.L. (2006). Homology modeling and site directed mutagenesis of pyroglutamyl peptidase II. Insights into omega versus aminopeptidase specificity in the M1 family.
Journal of Biological Chemistry,
281 (27),
18581-18590.
Artículo
42 - de Gortari,P., Uribe,R.M., Garcia-Vazquez,A., Aguilar-Valles,A., Martinez,A., Valdes,A., Charli,J.L., Fernandez-Guardiola,A., Joseph-Bravo,P. (2006). Amygdala kindling differentially regulates the expression of the elements involved in TRH transmission.
Neurochemistry International,
48 (1),
31-42.
Artículo
43 - Aguilar-Valles,A., Sanchez,E., de Gortari,P., Balderas,I., Ramirez-Amaya,V., Bermudez-Rattoni,F., Joseph-Bravo,P. (2005). Analysis of the Stress Response in Rats Trained in the Water-Maze: Differential Expression of Corticotropin-Releasing Hormone, CRH-R1, Glucocorticoid Receptors and Brain-Derived Neurotrophic Factor in Limbic Regions.
Neuroendocrinology,
82 (5-6),
306-319.
Artículo
44 - Chavez-Gutierrez,L., Bourdais,J., Aranda,G., Vargas,M.A., Matta-Camacho,E., Ducancel,F, Segovia,L., Joseph-Bravo,P., Charli,J.L. (2005). A truncated isoform of pyroglutamyl aminopeptidase II produced by exon extension has dominant-negative activity.
Journal of Neurochemistry,
92 (4),
807-817.
Artículo
45 - Cote-Velez,A., Perez-Martinez,L., Diaz-Gallardo,M.Y., Perez-Monter,C., Carreon,A., Charli,J.L., Joseph-Bravo,P. (2005). Dexamethasone repressed cAMP rapid upregulation of TRH gene transcription. Identification of a composite GRE and a CRE in TRH promoter.
Journal of Molecular Endocrinology,
34 (1),
177-197.
Artículo
46 - de Gortari,P., Romero,F., Cisneros,M., Joseph-Bravo,P. (2005). Acute administration of alcohol modulates pyroglutamyl amino peptidase II activity and mRNA levels in rat limbic regions.
Neurochemistry International,
46 (4),
347-356.
Artículo
47 - de Gortari,P., Cisneros,M., Joseph-Bravo,P. (2005). Chronic ethanol or glucose consumption alter TRH content and pyroglutamyl aminopeptidase II activity in rat limbic regions.
Regulatory Peptides,
127 (1-3),
141-150.
Artículo
48 - Cruz,R., Chavez-Gutierrez,L., Joseph-Bravo,P., Charli,J.L. (2004). 3,3',5'-Triiodo-L-Thyronine Reduces Efficiency of mRNA Knockdown by Antisense Oligodeoxynucleotides: A Study with Pyroglutamyl Aminopeptidase II in Adenohypophysis .
Oligonucleotides,
14 (3),
176-190.
Artículo
49 - Pascual,I., Cisneros,M., Lage,J., Diaz,J, Joseph-Bravo,P., Charli,J.L., Chavez,M.A. (2004). Isolation and purification of HcPI, a natural inhibitor of pyroglutamil aminopeptidase II (TRH-degrading ectoenzyme) from extracts of Hermodice carunculata (annelide: Polychaeta).
Revista Biologia,
18 (1),
38-49.
Artículo
50 - Pascual,I., Gil-Parrado,S., Cisneros,M., Joseph-Bravo,P., Diaz,J., Possani,L.D., Charli,J.L., Chavez,M. (2004). Purification of a specific inhibitor of pyroglutamyl aminopeptidase II from the marine annelide Hermodice carunculata. In vivo effects in rodent brain.
International Journal of Biochemistry and Cell Biology,
36 (1),
138-152.
Artículo
51 - de Gortari,P., Cisneros,M., Medellin,M.A., Joseph-Bravo,P. (2002). Chronic ingestion of ethanol or glucose solutions affects hypothalamic and limbic TRH metabolism in dams and their pups.
Neurochemistry International,
41 (4),
237-249.
Artículo
52 - Joseph-Bravo,P., Perez-Martinez,L., Lezama,L., Morales-Chapa,C., Charli,J.L. (2002). An improved method for the expression of TRH in serum-supplemented primary cultures of fetal hypothalamic cells.
Brain Research Protocols,
9 (2),
93-104.
Artículo
53 - Vargas,M.A., Uribe,R.M., Cisneros,M., Romero,F., Gonzalez,S., Joseph-Bravo,P., Charli,J.L. (2002). Thyrotropin-releasing hormone regulates the diurnal variation of pyroglutamyl aminopeptidase II activity in the male rat adenohypophysis.
European Journal of Endocrinology,
147 (3),
363-369.
Artículo
54 - Vargas,M.A., Cisneros,M., Joseph-Bravo,P., Charli,J.L. (2002). Thyrotropin-releasing hormone-induced down-regulation of pyroglutamyl aminopeptidase II activity involves L-type calcium channels and cam kinase activities in cultures of adenohypophyseal cells.
Journal of Neuroendocrinology,
14 (3),
184-193.
Artículo
55 - Baeza,M.A., Ponce,G., Joseph-Bravo,P., Charli,J.L. (2001). Rapid down regulation of pyroglutamyl peptidase II activity by arachidonic acid in primary cultures of adenohypophyseal cells.
Life Sciences,
68 (17),
2051-2060.
Artículo
56 - Guerra-Crespo,M., Ubieta,R., Joseph-Bravo,P., Charli,J.L., Perez-Martinez,L. (2001). BDNF increases the early expression of TRH mRNA in fetal TrkB+ hypothalamic neurons in primary culture.
European Journal of Neuroscience,
14 (3),
483-494.
Artículo
57 - Perez-Martinez,L., Charli,J., Joseph-Bravo,P. (2001). Development of pro-TRH gene expression in primary cultures of fetal hypothalamic cells.
Developmental Brain Research,
130 (1),
73-81.
Artículo
58 - Sanchez,E., Uribe,R.M., Corkidi,G., Zoeller,R.T., Cisneros,M., Zacarias,M., Morales-Chapa,C., Charli,J.L., Joseph-Bravo,P. (2001). Differential Responses of Thyrotropin-Releasing Hormone (TRH) Neurons to Cold Exposure or Suckling Indicate Functional Heterogeneity of the TRH System in the Paraventricular Nucleus of the Rat Hypothalamus.
Neuroendocrinology,
74 (6),
407-422.
Artículo
59 - Bourdais,J., Romero,F., Uriostegui,B., Cisneros,M., Joseph-Bravo,P., Charli,J.L. (2000). [3-Me-His(2)]-TRH combined with dopamine withdrawal rapidly and transiently increases pyroglutamyl aminopeptidase II activity in primary cultures of adenohypophyseal cells.
Neuropeptides,
34 (2),
83-88.
Artículo
60 - de Gortari,P., Gonzalez-Alzati,M.E., Cisneros,M., Joseph-Bravo,P. (2000). Effect of fasting on the content of thyrotropin-releasing hormone and its mRNA in the central nervous system and pyroglutamyl peptidase II activity in the anterior pituitary of post-weaned and adult rats.
Nutritional Neuroscience,
3 (4),
255-265.
Revisión
61 - de Gortari,P., Mendez,M., Rodriguez-Keller,I., Perez-Martinez,L., Joseph-Bravob,P. (2000). Acute ethanol administration induces changes in TRH and proenkephalin expression in hypothalamic and limbic regions of rat brain.
Neurochemistry International,
37 (5-6),
483-496.
Artículo
62 - Niquet,J., Perez-Martinez,L., Guerra,M., Grouselle,D., Joseph-Bravo,P., Charli,J. (2000). Extracellular matrix proteins increase the expression of pro-TRH and pro-protein convertase PC1 in fetal hypothalamic neurons in vitro.
Developmental Brain Research,
120 (1),
49-56.
Artículo
63 - Vargas,M.A., Cisneros,M., Joseph-Bravo,P., Charli,J.L. (2000). Regulation of adenohypophyseal pyroglutamyl aminopeptidase II activity by thyrotropin-releasing hormone and phorbol esters.
Endocrine,
13 (3),
267-272.
Artículo
64 - Mendez,M., Cisneros,M., Baez,A., Joseph-Bravo,P., Charli,J.L. (1999). Three TRH-like molecules are released from rat hypothalamus in vitro.
Neurochemical Research,
24 (7),
815-823.
Artículo
65 - Perez-Martinez,L., Uribe,R.M., Sanchez,E., Carreon-Rodriguez,A., Chavez,L., Zacarias,M., Joseph-Bravo,P., Charli,J.L. (1999). Regulation of TRH biosynthesis in the paraventricular nucleus of rodent hypothalamus.
Current topics in neurochemistry,
2,
79-88.
Artículo; Actas Paper
66 - Charli,J.L., Vargas,M.A., Cisneros,M., de Gortari,P., Baeza,M.A., Jasso,P., Bourdais,J., Perez,L., Uribe,R.M., Joseph-Bravo,P. (1998). TRH inactivation in the extracellular compartment: role of pyroglutamyl peptidase II.
Neurobiology (Bp.),
6 (1),
45-57.
Artículo
67 - de Gortari,P., Joseph-Bravo,P., Monroy-Ruiz,J., Martinez,A., Cisneros,M., Fernandez-Guardiola,A. (1998). Brain thyrotropin-releasing hormone content varies through amygdaloid kindling development according to afterdischarge frequency and propagation.
Epilepsia,
39 (8),
897-903.
Revisión
68 - Joseph-Bravo,P., Uribe,R.M., Vargas,M.A., Perez-Martinez,L., Zoeller,T., Charli,J.L. (1998). Multifactorial modulation of TRH metabolism.
Cellular & Molecular Neurobiology,
18 (2),
231-247.
Artículo
69 - Perez-Martinez,L., Carreon-Rodriguez,A., Gonzalez-Alzati,M.E., Morales,C., Charli,J.L., Joseph-Bravo,P. (1998). Dexamethasone rapidly regulates TRH mRNA levels in hypothalamic cell cultures: interaction with the cAMP pathway.
Neuroendocrinology,
68 (5),
345-354.
Artículo
70 - Vargas,M.A., Bourdais,J., Sanchez,S., Uriostegui,B., Moreno,E., Joseph-Bravo,P., Charli,J.L. (1998). Multiple hypothalamic factors regulate pyroglutamyl peptidase II in cultures of adenohypophyseal cells: role of the cAMP pathway.
Journal of Neuroendocrinology,
10 (3),
199-206.
Artículo
71 - Sanchez,E., Charli,J.L., Morales,C., Corkidi,G., Seidah,N.G., Joseph-Bravo,P., Uribe,R.M. (1997). Expression of the proprotein convertases PC1 and PC2 mRNAs in thyrotropin releasing hormone neurons of the rat paraventricular nucleus of hypothalamus.
Brain Research,
761 (1),
77-86.
Artículo
72 - de Gortari,P., Fernandez-Guardiola,A., Martinez,A., Cisneros,M., Joseph-Bravo,P. (1995). Changes in TRH and its degrading enzyme pyroglutamyl peptidase II, during the development of amygdaloid kindling.
Brain Research,
679 (1),
144-150.
Artículo
73 - Uribe,R.M., Joseph-Bravo,P., Charli,J.L. (1995). Pups removal enhances thyrotropin-releasing hormone mRNA in the hypothalamic paraventricular nucleus.
European Journal of Endocrinology,
133 (3),
354-360.
Artículo
74 - Uribe,R.M., Perez-Martinez,L., Covarrubias,M.D., Gomez,O., Covarrubias,L., Charli,J.L., Joseph-Bravo,P. (1995). Phorbol ester or cAMP enhance thyrotropin-releasing hormone mRNA in primary cultures of hypothalamic cells.
Neuroscience Letters,
201 (1),
41-44.
Artículo
75 - Covarrubias,L., Redondo,J.L., Vargas,M.A., Uribe,R.M., Mendez,M., Joseph-Bravo,P., Charli,J.L. (1994). In vitro TRH release from hypothalamus slices varies during the diurnal cycle.
Neurochemical Research,
19 (7),
845-850.
Carta
Artículo
77 - Joseph-Bravo,P., Fresan,M., Cisneros,M., Vargas,M.A., Charli,J.L. (1994). Pyroglutamyl peptidase II activity is not in the processes of bulbospinal TRHergic neurons.
Neuroscience Letters,
178 (2),
243-246.
Artículo
78 - Uribe,R.M., Joseph-Bravo,P., Ponce,G., Cisneros,M., Aceves,C., Charli,J.L. (1994). Influence of thyroid status on TRH metabolism in rat olfactory bulb.
Peptides,
15 (3),
435-439.
Artículo
79 - Vargas,M.A., Joseph-Bravo,P., Charli,J.L. (1994). Thyrotropin-releasing hormone downregulates pyroglutamyl peptidase II activity in adenohypophyseal cells.
Neuroendocrinology,
60 (3),
323-330.
Artículo
80 - Brakch,N., Boileau,G., Simonetti,M., Nault,C., Joseph-Bravo,P., Rholam,M., Cohen,P. (1993). Prosomatostatin processing in Neuro2A cells. Role of beta-turn structure in the vicinity of the Arg-Lys cleavage site.
European Journal of Biochemistry,
216 (1),
39-47.
*
Artículo
81 - Uribe,R.M., Redondo,J.L., Charli,J.L., Joseph-Bravo,P. (1993). Suckling and cold stress rapidly and transiently increase TRH mRNA in the paraventricular nucleus.
Neuroendocrinology,
58 (1),
140-145.
Artículo
82 - Vargas,M.A., Cisneros,M., Herrera,J., Joseph-Bravo,P., Charli,J.L. (1992). Regional distribution of pyroglutamyl peptidase II in rabbit brain, spinal cord, and organs.
Peptides,
13 (2),
255-260.
Artículo
83 - Cruz,C., Charli,J.L., Vargas,M.A., Joseph-Bravo,P. (1991). Neuronal localization of pyroglutamate aminopeptidase II in primary cultures of fetal mouse brain.
Journal of Neurochemistry,
56 (5),
1594-1601.
Artículo
84 - Lepage-Lezin,A., Joseph-Bravo,P., Devilliers,G., Benedetti,L., Launay,J.M., Gomez,S., Cohen,P. (1991). Prosomatostatin is processed in the Golgi apparatus of rat neural cells.
Journal of Biological Chemistry,
266 (3),
1679-1688.
*
Artículo
85 - Uribe,R.M., Joseph-Bravo,P., Pasten,J., Ponce,G., Mendez,M., Covarrubias,L., Charli,J.L. (1991). Some events of thyrotropin-releasing hormone metabolism are regulated in lactating and cycling rats.
Neuroendocrinology,
54 (5),
493-498.
Artículo
86 - Mendez,M., Cruz,C., Joseph-Bravo,P., Wilk,S., Charli,J.L. (1990). Evaluation of the role of prolyl endopeptidase and pyroglutamyl peptidase I in the metabolism of LHRH and TRH in brain.
Neuropeptides,
17 (2),
55-62.
Artículo
87 - Charli,J.L., Mendez,M., Vargas,M.A., Cisneros,M., Assai,M., Joseph-Bravo,P., Wilk,S. (1989). Pyroglutamyl peptidase II inhibition specifically increases recovery of TRH released from rat brain slices.
Neuropeptides,
14 (3),
191-196.
Artículo
88 - Charli,J.L., Cruz,C., Ponce,G., Vargas,M.A., Mendez,M., Cisneros,M., Pasten,J., Joseph-Bravo,P. (1989). Physiological relevance of pyroglutamate aminopeptidase II.
Annals of the New York Academy of Sciences,
553,
563-564.
Artículo
89 - Covarrubias,L., Uribe,R.M., Mendez,M., Charli,J.L., Joseph-Bravo,P. (1989). Hypothalamic TRH mRNA regulation under different physiological conditions.
Annals of the New York Academy of Sciences,
553,
476-478.
Artículo
90 - Charli,J.L., Cruz,C., Vargas,M., Joseph-Bravo,P. (1988). The narrow specificity pyroglutamate aminopeptidase degrading TRH in brain is an ectoenzyme.
Neurochemistry International,
13,
237-242.
Artículo
91 - Covarrubias,L., Uribe,R.M., Mendez,M., Charli,J.L., Joseph-Bravo,P. (1988). Neuronal TRH synthesis: developmental and circadian TRH mRNA levels.
Biochemical and Biophysical Research Communications,
151 (1),
615-622.
Artículo
92 - Charli,J.L., Mendez,M., Joseph-Bravo,P., Wilk,S. (1987). Specific inhibitors of pyroglutamyl peptidase I and prolyl endopeptidase do not change the in vitro release of TRH or its content in rodent brain.
Neuropeptides,
9 (4),
373-378.
Artículo
93 - Mendez,M., Joseph-Bravo,P., Cisneros,M., Vargas,M.A., Charli,J.L. (1987). Regional distribution of in vitro release of thyrotropin releasing hormone in rat brain.
Peptides,
8 (2),
291-298.
Artículo
94 - Saavedra,R., Bravo,P.J., Charli,J.L., Herion,P. (1987). Characterization of high affinity monoclonal antibodies against the luteinizing hormone-releasing hormone.
Hybridoma,
6 (6),
663-672.
Artículo
95 - Vargas,M., Mendez,M., Cisneros,M., Joseph-Bravo,P., Charli,J.L. (1987). Regional distribution of the membrane-bound pyroglutamate amino peptidase-degrading thyrotropin-releasing hormone in rat brain.
Neuroscience Letters,
79 (3),
311-314.
Artículo
96 - Cohen,S., Charli,J.L., Diaz de Leon,L., Millar,R.P., Arimura,A., Morrison,M.R., Joseph-Bravo,P. (1986). Attempts to immunoprecipitate the LHRH precursor synthesized in cell free systems.
Brain Research Bulletin,
16 (3),
309-314.
Artículo
97 - Torres,H., Charli,J.L., Vargas,M.A., Gonzalez-Noriega,A., Joseph-Bravo,P. (1986). Subcellular distribution of the enzymes degrading Thyrotropin releasing hormone and metabolites in rat brain.
Neurochemistry International,
9,
103-110.
Artículo
98 - Garat,B., Miranda,J., Charli,J.L., Joseph-Bravo,P. (1985). Presence of a membrane bound pyroglutamyl amino peptidase degrading thyrotropin releasing hormone in rat brain.
Neuropeptides,
6 (1),
27-40.
Artículo
99 - Charli,J.L., Ponce,G., McKelvy,J.F., Joseph-Bravo,P. (1984). Accumulation of thyrotropin releasing hormone by rat hypothalamic slices.
Journal of Neurochemistry,
42 (4),
981-986.
Artículo
100 - Pacheco,M.F., McKelvy,J.F., Woodward,D.J., Loudes,C., Joseph-Bravo,P., Krulich,L., Griffin,W.S. (1981). TRH in the rat cerebellum: I. Distribution and concentration.
Peptides,
2 (3),
277-282.
*
Artículo
101 - Joseph-Bravo,P., Charli,J.L., Sherman,T., Boyer,H., Bolivar,F., McKelvy,J.F. (1980). Identification of a putative hypothalamic mRNA coding for somatostatin and of its product in cell-free translation.
Biochemical and Biophysical Research Communications,
94 (3),
1004-1012.
*
Artículo
102 - Joseph-Bravo,P., Loudes,C., Charli,J.L., Kordon,C. (1979). Subcellular distribution of brain peptidases degrading luteinizing hormone releasing hormone (LHRH) and thyrotropin releasing hormone (TRH).
Brain Research,
166 (2),
321-329.
*
Artículo
103 - Joseph-Bravo,P., Charli,J.L., Palacios,J.M., Kordon,C. (1979). Effect of neurotransmitters on the in vitro release of immunoreactive thyrotropin-releasing hormone from rat mediobasal hypothalamus.
Endocrinology,
104 (3),
801-806.
*
Artículo
104 - Lin,C., Joseph-Bravo,P., Sherman,T., Chan,L., McKelvy,J.F. (1979). Cell-free synthesis of putative neurophysin precursors from rat and mouse hypothalamic poly (A)-RNA.
Biochemical and Biophysical Research Communications,
89 (3),
943-950.
*
Artículo
105 - Loudes,C., Joseph-Bravo,P., Leblanc,P., Kordon,C. (1978). Specific activity of LHRH and TRH degrading enzymes in various tissues of normal and castrated male rats.
Biochemical and Biophysical Research Communications,
83 (3),
921-926.
*
Artículo
106 - Joseph-Bravo,P.I., Findley,M., Newberne,P.M. (1976). Some interactions of light, riboflavin, and aflatoxin B1 in vivo and in vitro.
Journal of Toxicology and Environmental Health,
1 (3),
353-376.
*
Internacional
107 - Joseph-Bravo, P., Gutierrez-Mariscal, M., Jaimes-Hoy, L., Charli, J. L. (2019). Thyroid Axis and Energy Balance: Focus on Animals and Implications for Humankind. Handbook of Famine, Starvation, and Nutrient Deprivation: From Biology to Policy.
1099-1126,
Cham, Suiza: Springer.
Nacional
108 - de Gortari,P., Joseph-Bravo,P. (2010). Regulacion neuroendocrina del apetito. Obesidad. Un enfoque multidisciplinario .
57-71,
Pachuca.
Nacional
109 - Charli,J.L., Joseph-Bravo,P. (2008). El cerebro, la comunicación intercelular y los p?ptidos. Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 5.
53-64,
Mexico, D.F..
Nacional
110 - Joseph-Bravo,P., de Gortari,P. (2008). El estrés y sus efectos en el metabolismo y el aprendizaje. Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 6.
65-76,
Mexico, D.F..
Memoria in extenso
111 - Joseph-Bravo,P., Mariscal,M., Garcia,I., Jaimes-Hoy,L., Charli,J.L., de Gortari,P. (2007). Response of limbic TRH neurons depends on the stress paradigm. Endocrine Regulations. Int. Congress of Stress.
96-.
Internacional
112 - de Gortari,P., Joseph,P. (2006). Neuroendocrine Regulation of Energy Metabolism. Molecular Endocrinology.
65-86,
Kerala, India: Research Signpost.
Internacional
113 - Joseph-Bravo,P., Cote-Velez,A., Perez-Martinez,L. (2006). Integration of Neuroendocrine Signals that Regulate the Activity of Hypophysiotropic Peptides. Molecular Endocrinology.
1-24,
Kerala, India: Research Signpost.
Nacional
114 - Joseph-Bravo,P. (1995). Choques, transtornos y otras caídas. Stress, dolor y p?ptidos. Memoria del Curso Explorando el Cerebro.
35-37,
Mexico,D.F..
Memoria in extenso
115 - Charli,J.L., Garat,B., Martinez-Escalera,G., Ponce,G., Miranda,J., Joseph-Bravo,P. (1984). METABOLISM OF THYROTROPIN RELEASING HORMONE AND ITS POSSIBLE RELEVANCE TO PROLACTIN SECRETION. Prolactin Secretion: a Multidisciplinary Approach.
239-248,
Orlando: Academic Press.
Memoria in extenso
116 - Kordon,C., Enjalbert,A., Hery,M., Joseph-Bravo,P., Rotsztjen,W., Ruberg.M. (1979). Role of neurotransmitters in the control of adenohypophyseal secretion. Handbook of the hypothalamus.
253-306,
2,
New York.
*
Internacional
Nacional
118 - Carreon-Rodriguez,A., Perez-Martinez,L., Joseph-Bravo,P. (2008). La participación de las hormonas tiroideas en el desarrollo y función del sistema nervioso.
Facultad de Medicina. Revista Actualidades de Posgrado para el Médico General,
12 (5),
9-12.
Editorial Material
119 - Joseph-Bravo,P. (2004). Hypophysiotropic thyrotropin-releasing hormone neurons as transducers of energy homeostasis.
Endocrinology,
145 (11),
4813-4815.
Note
120 - Charli,J.L., Cruz,C., Redondo,J.L., Guerra,C., Joseph-Bravo,P. (1995). Homologous conditioned medium enhances expression of TRH in hypothalamic neurons in primary culture.
Developmental Brain Research,
89 (1),
155-160.
Note
121 - Mendez,M., Moran,J., Wilk,S., Joseph-Bravo,P., Charli,J.L. (1993). Assessment of the role of TRH in the release of [3H]-dopamine from rat nucleus accumbens-lateral septum slices.
Brain Research Bulletin,
31 (5),
621-625.
Note
122 - Vargas,M.A., Herrera,J., Uribe,R.M., Charli,J.L., Joseph-Bravo,P. (1992). Ontogenesis of pyroglutamyl peptidase II activity in rat brain, adenohypophysis and pancreas.
Developmental Brain Research,
66 (2),
251-256.
Note
123 - Fuchs,L.Y., Ovando,C., Joseph,P., Soberon,X., Charli,J.L. (1990). Repetitive DNA sequence from the crayfish Procambarus clarkii.
Nucleic Acids Research,
18 (6),
1650.
Note
124 - Ponce,G., Charli,J.L., Pasten,J.A., Aceves,C., Joseph-Bravo,P. (1988). Tissue-specific regulation of pyroglutamate aminopeptidase II activity by thyroid hormones.
Neuroendocrinology,
48 (2),
211-213.
Nacional
125 - Charli,J.L., Ponce,G., Torres,H., Garat,B., Barquin,N., Bravo,P.J. (1983). [Cellular biochemistry of hypophysiotropic peptides. II. Liberation, action and inactivation].
Boletin de estudios medicos y biologicos,
32 (7-8 Suppl 1),
243-252.
Nacional
126 - Joseph-Bravo,P., Theleen,M., de Gortari,P., Shapiro,E., Redondo,J.L., Briones,M., Merchant,H., Charli,J.L. (1983). [Biochemistry of hypophysiotropic peptides. I. Biosynthesis and its regulation].
Boletin de estudios medicos y biologicos,
32 (7-8 Suppl 1),
233-241.
Nacional
127 - Charli,J.L., Joseph-Bravo,P., Robert,M. (1980). Use of synthetic oligonucleotides for identification of messenger RNA for somatostatin.
Boletin de estudios medicos y biologicos,
31 (3-4),
220-221.
*
Note
128 - Charli,J.L., Joseph-Bravo,P., Palacios,J.M., Kordon,C. (1978). Histamine-induced release of thyrotropin releasing hormone from hypothalamic slices.
European Journal of Pharmacology,
52 (3-4),
401-403.
*
129 - Joseph-Bravo, Patricia (1972). Efecto de la melatonina sobre el metabolismo de aminas biogenicas en sistema nervioso central .
Facultad de Quimica,
Quimico,
UNAM.
Artículo
130 - Castillo-Campos,A., Gutierrez-Mata,A., Charli,J.L., Joseph-Bravo,P.. Chronic stress inhibits hypothalamus-pituitary-thyroid axis and brown adipose tissue responses to acute cold exposure in male rats.
Journal of Endocrinological Investigation,
44,
713.
Artículo
131 - Jaimes-Hoy,L., Perez-Maldonado,A., Narvaez-Bahena,E., de la Cruz Guarneros,N., Rodriguez-Rodriguez,A., Charli,J.L., Soberon,X., Joseph-Bravo,P.. Sex dimorphic changes in Trh gene methylation and thyroid-axis response to energy demands in maternally-separated rats.
Endocrinology,
May 27 Online ahead of print.
Revisión
132 - Lazcano,I., Rodriguez-Rodriguez,A., Uribe,R.M., Orozco,A., Joseph-Bravo,P., Charli,J.L.. Evolution of thyrotropin-releasing factor extracellular communication units.
General and Comparative Endocrinology,
305,
113642.
Revisión
133 - Charli,J.L., Rodriguez-Rodriguez,A., Hernandez-Ortega,K., Cote-Velez,A., Uribe,R.M., Jaimes-Hoy,L., Joseph-Bravo,P.. The Thyrotropin-Releasing Hormone-Degrading Ectoenzyme, a Therapeutic Target?.
Frontiers in Pharmacology,
11,
640.
Artículo
134 - Farkas,E., Varga,E., Kovacs,B., Szilvasy-Szabo,A., Cote-Velez,A., Peterfi,Z., Matziari,M., Toth,M., Zelena,D., Mezriczky,Z., Kadar,A., Kovari,D., Watanabe,M., Kano,M., Mackie,K., Rozsa,B., Ruska,Y., Toth,B., Mate,Z., Erdelyi,F., Szabo,G., Gereben,B., Lechan,R.M., Charli,J.L., Joseph-Bravo,P., Fekete,C.. A glial-neuronal circuit in the median eminence regulates thyrotropin-releasing hormone-release via the endocannabinoid system.
iScience,
23 (3),
100921.
Artículo
135 - Joseph-Bravo,P., Lazcano,I., Jaimes-Hoy,L., Gutierrez-Mariscal,M., Sanchez-Jaramillo,E., Uribe,R.M., Charli,J.L.. Sexually dimorphic dynamics of thyroid axis activity during fasting in rats.
Frontiers in Bioscience, Landmark,
25 (7),
1305-1323.
Artículo
136 - Jaimes-Hoy,L., Romero,F., Charli,J.L., Joseph-Bravo,P.. Sex Dimorphic Responses of the Hypothalamus-Pituitary-Thyroid Axis to Maternal Separation and Palatable Diet.
Frontiers in Endocrinology,
10,
445.
Artículo
137 - Parra-Montes de Oca, M. A., Gutierrez-Mariscal, M., Salmeron-Jimenez, M. F., Jaimes-Hoy, L., Charli, J. L., Joseph-Bravo, P.. Voluntary Exercise-Induced Activation of Thyroid Axis and Reduction of White Fat Depots Is Attenuated by Chronic Stress in a Sex Dimorphic Pattern in Adult Rats.
Frontiers in Endocrinology,
10,
418.
Revisión
138 - Rodriguez-Rodriguez, A., Lazcano, I., Sanchez-Jaramillo, E., Uribe, R. M., Jaimes-Hoy, L., Joseph-Bravo, P., Charli, J. L.. Tanycytes and the Control of Thyrotropin-Releasing Hormone Flux Into Portal Capillaries.
Frontiers in Endocrinology,
10,
401.
Internacional
139 - Joseph-Bravo, P., Gutierrez-Mariscal, M., Jaimes-Hoy, L., Charli, J. L.. Thyroid Axis and Energy Balance: Focus on Animals and Implications for Humankind. Handbook of Famine, Starvation, and Nutrient Deprivation: From Biology to Policy.
1099-1126,
Cham, Suiza: Springer.
Artículo
140 - Cote-Velez, A., Martinez-Baez A., Lezama, L., Uribe, R.M., Joseph-Bravo, P., Charli, J.L.. A screen for modulators reveals that orexin-A rapidly stimulates thyrotropin releasing hormone expression and release in hypothalamic cell culture.
Neuropeptides,
62,
11-20.
Artículo
141 - Gonzalez-Franco, D.A., Ramirez-Amaya, V., Joseph-Bravo, P., Prado-Alcala, R.A., Quirarte, G.L.. Differential Arc protein expression in dorsal and ventral striatum after moderate and intense inhibitory avoidance training.
Neurobiology of Learning and Memory,
140,
17-26.
Artículo
142 - Jaimes-Hoy, L., Gurrola, G.B., Cisneros, M., Joseph-Bravo, P., Possani, L.D., Charli, J.L.. The Kv1.3 channel blocker Vm24 enhances muscle glucose transporter 4 mobilization but does not reduce body-weight gain in diet-induced obese male rats.
Life Sciences,
181,
23-30.
Artículo
Artículo
144 - Jaimes-Hoy,L., Gutierrez-Mariscal,M., Vargas,Y., Perez-Maldonado,A., Romero,F., Sanchez-Jaramillo,E., Charli,J.L., Joseph-Bravo,P.. Neonatal maternal separation alters, in a sex specific manner, the expression of TRH, of TRH-degrading ectoenzyme in the rat hypothalamus, and the response of the thyroid axis to starvation.
Endocrinology,
157 (8),
3253-3265.
Revisión
145 - Joseph-Bravo,P., Jaimes-Hoy,L., Charli,J.L.. Advances in TRH signaling.
Reviews in Endocrine and Metabolic Disorders,
17 (4),
545-558.
Revisión
146 - Joseph-Bravo,P., Jaimes-Hoy,L., Charli,J.. Regulation of TRH neurons and energy homeostasis related signals under stress.
Journal of Endocrinology,
224 (3),
R139-R159 [erratum en vol 227 (3) X1].
Revisión
147 - Joseph-Bravo,P., Jaimes-Hoy,L., Uribe,R.M., Charli,J.L.. TRH, first hypophysiotropic releasing hormone isolated: its control of pituitary-thyroid axis.
Journal of Endocrinology,
226 (2),
T85-T100 [erratum en vol 227 (3) X3].
Artículo
148 - Lazcano,I., Cabral,A., Uribe,R.M., Jaimes-Hoy,L., Perello,M., Joseph-Bravo,P., Sanchez-Jaramillo,E., Charli,J.L.. Fasting enhances pyroglutamyl peptidase II activity in tanycytes of the mediobasal hypothalamus of male adult rats.
Endocrinology,
156 (7),
2713-2723.
Artículo
149 - Rodriguez-Molina,V., Patino,J., Vargas,Y., Sanchez-Jaramillo,E., Joseph-Bravo,P., Charli,J.L.. TRH regulates action potential shape in cerebral cortex pyramidal neurons.
Brain Research,
1571,
1-11.
Artículo
150 - Sotelo-Rivera,I., Jaimes-Hoy,L., Cote-Velez,A., Espinoza-Ayala,C., Charli,J.L., Joseph-Bravo,P.. An acute injection of corticosterone increases thyrotrophin releasing hormone expression in the paraventricular nucleus of the hypothalamus but interferes with the rapid hypothalamus pituitary thyroid axis response to cold in male rats.
Journal of Neuroendocrinology,
26 (12),
861-869.
Artículo
151 - Uribe,R.M., Jaimes-Hoy,L., Ramirez-Martinez,C., Garcia-Vazquez,A., Romero,F., Cisneros,M., Cote-Velez,A., Charli,J.L., Joseph-Bravo,P.. Voluntary exercise adapts the hypothalamus-pituitary-thyroid axis in male rats.
Endocrinology,
155 (5),
en20131724.
Artículo
152 - Gutierrez-Mariscal,M., Sanchez,E., Rebolledo-Solleiro,D., Garcia-Vazquez,A.I., Cote-Velez,A., Acasuso-Rivero,C., Charli,J.L., Joseph-Bravo,P.. The acute response of the amygdalar TRH system to psychogenic stressors varies dependent on the paradigm and circadian condition.
Brain Research,
1452,
73-84.
Artículo
153 - Gutierrez-Mariscal,M., Sanchez,E., Garcia-Vazquez,A., Rebolledo-Solleiro,D., Charli,J.L., Joseph-Bravo,P.. Acute response of hypophysiotropic thyrotropin releasing hormone neurons and thyrotropin release to behavioural paradigms producing varying intensities of stress and physical activity.
Regulatory Peptides,
179 (1-3),
61-70.
Artículo
154 - Lazcano,I., Uribe,R.M., Martinez-Chavez,Erick, Vargas,M.A., Matziari,M., Joseph-Bravo,P., Charli,J.L.. Pyroglutamyl peptidase II inhibition enhances the analeptic effect of thyrotropin releasing hormone in the rat medial septum.
Journal of Pharmacology and Experimental Therapeutics,
342 (1),
222-231.
Artículo
155 - Cote-Velez,A., Perez-Maldonado,A., Osuna,J., Barrera,B., Charli,J.L., Joseph-Bravo,P.. Creb and Sp/Kruppel response elements cooperate to control rat TRH gene transcription in response to cAMP.
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms,
1809 (3),
191-199.
Artículo
156 - Guerra-Crespo,M., Perez-Monter,C., Janga,S.C., Castillo-Ramirez,S., Gutierrez-Rios,R.M., Joseph-Bravo,P., Perez-Martinez,L., Charli,J.L.. Transcriptional profiling of fetal hypothalamic TRH neurons.
BMC Genomics,
12 (1),
222.
Artículo
157 - Uribe,R.M., Cisneros,M., Vargas,M.A., Lezama,L., Cote-Velez,A., Joseph-Bravo,P., Charli,J.L.. The systemic inhibition of nitric oxide production rapidly regulates TRH mRNA concentration in the paraventricular nucleus of the hypothalamus and serum TSH concentration. Studies in control and cold-stressed rats.
Brain Research,
1367,
188-197.
Artículo
158 - Diaz-Gallardo,M.Y., Cote-Velez,A., Charli,J.L., Joseph-Bravo,P.. A rapid interference between glucocorticoids and cAMP-activated signaling in hypothalamic neurons prevents binding of pCREB and GR at the CRE-like and composite GRE sites of TRH gene promoter.
Journal of Neuroendocrinology,
22 (4),
282-293.
Artículo; Actas Paper
159 - Diaz-Gallardo,M.Y., Cote-Velez,A., Carreon-Rodriguez,A., Charli,J.L., Joseph-Bravo,P.. Phosphorylated Cyclic-AMP-Response Element-Binding Protein and Thyroid Hormone Receptor Have Independent Response Elements in the Rat Thyrotropin-Releasing Hormone Promoter: An Analysis in Hypothalamic Cells.
Neuroendocrinology,
91 (1),
64-76.
Nacional
160 - de Gortari,P., Joseph-Bravo,P.. Regulacion neuroendocrina del apetito. Obesidad. Un enfoque multidisciplinario .
57-71,
Pachuca.
Artículo
161 - de Gortari,P., Mancera,K., Cote-Velez,A., Amaya,M.I., Martinez,A., Jaimes-Hoy,L., Joseph-Bravo,P.. Involvement of CRH-R2 receptor in eating behavior and in the response of the HPT axis in rats subjected to dehydration-induced anorexia.
Psychoneuroendocrinology,
34 (2),
259-272.
Artículo
162 - Rodriguez-Molina,V., Vargas,M.A., Joseph-Bravo,P., Charli,J.L.. NMDA receptor up-regulates pyroglutamyl peptidase II activity in the rat hippocampus.
Neuroscience Letters,
449 (3),
211-214.
Artículo
163 - Uribe,R.M., Zacarias,M., Corkidi,G., Cisneros,M., Charli,J.L., Joseph-Bravo,P.. 17beta-oestradiol indirectly inhibits trh expression in the hypothalamic paraventricular nucleus of female rats and blunts thyroid axis response to cold exposure.
Journal of Neuroendocrinology,
21 (5),
439-448.
Artículo
164 - Cote-Velez,A., Perez-Martinez,L., Charli,J.L., Joseph-Bravo,P.. The PKC and ERK/MAPK Pathways Regulate Glucocorticoid Action on TRH Transcription.
Neurochemical Research,
33 (8),
1582-1591.
Artículo
165 - Cruz,R., Vargas,M.A., Uribe,R.M., Pascual,I., Lazcano,I., Yiotakis,A., Matziari,M., Joseph-Bravo,P., Charli,J.L.. Anterior pituitary pyroglutamyl peptidase II activity controls TRH-induced prolactin release.
Peptides,
29 (11),
1953-1964.
Revisión
166 - Gutierrez-Mariscal,M., de Gortari,P., Lopez-Rubalcava,C., Martinez,A., Joseph-Bravo,P.. Analysis of the anxiolytic-like effect of TRH and the response of amygdalar TRHergic neurons in anxiety.
Psychoneuroendocrinology,
33 (2),
198-213.
Artículo
167 - Jaimes-Hoy,L., Joseph-Bravo,P., de Gortari,P.. Differential response of TRHergic neurons of the hypothalamic paraventricular nucleus (PVN) in female animals submitted to food-restriction or dehydration-induced anorexia and cold exposure.
Hormones and Behavior,
53 (2),
366-377.
Nacional
168 - Charli,J.L., Joseph-Bravo,P.. El cerebro, la comunicación intercelular y los p?ptidos. Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 5.
53-64,
Mexico, D.F..
Nacional
169 - Joseph-Bravo,P., de Gortari,P.. El estrés y sus efectos en el metabolismo y el aprendizaje. Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 6.
65-76,
Mexico, D.F..
Nacional
170 - Carreon-Rodriguez,A., Perez-Martinez,L., Joseph-Bravo,P.. La participación de las hormonas tiroideas en el desarrollo y función del sistema nervioso.
Facultad de Medicina. Revista Actualidades de Posgrado para el Médico General,
12 (5),
9-12.
Revisión
171 - Aguilar-Valles,A., Sanchez,E., de Gortari,P., Garcia-Vazquez,A.I., Ramirez-Amaya,V., Bermudez-Rattoni,F., Joseph-Bravo,P.. The expression of TRH, its receptors and degrading enzyme is differentially modulated in the rat limbic system during training in the Morris water maze.
Neurochemistry International,
50 (2),
404-417.
Artículo
172 - de Gortari,P., Vargas,M.A., Martinez,A., Garcia-Vazquez,A.I., Uribe,R.M., Chavez-Gutierrez,L., Magdaleno,V., Boileau,G., Charli,J.L., Joseph-Bravo,P.. Stage-specific Modulation of Neprilysin and Aminopeptidase N in the Limbic System During Kindling Progression.
Journal of Molecular Neuroscience,
33 (3),
252-261.
Artículo
173 - Sanchez,E., Fekete,C., Lechan,R.M., Joseph-Bravo,P.. Cocaine- and amphetamine-regulated transcript (CART) expression is differentially regulated in the hypothalamic paraventricular nucleus of lactating rats exposed to suckling or cold stimulation.
Brain Research,
1132 (1),
120-128.
Artículo
174 - Ubieta,R., Uribe,R.M., Gonzalez,J.A., Garcia-Vazquez,A., Perez-Monter,C., Perez-Martinez,L., Joseph-Bravo,P., Charli,J.L.. BDNF up-regulates pre-pro-TRH mRNA expression in the fetal/neonatal paraventricular nucleus of the hypothalamus. Properties of the transduction pathway.
Brain Research,
1174,
28-38.
Memoria in extenso
175 - Joseph-Bravo,P., Mariscal,M., Garcia,I., Jaimes-Hoy,L., Charli,J.L., de Gortari,P.. Response of limbic TRH neurons depends on the stress paradigm. Endocrine Regulations. Int. Congress of Stress.
96-.
Artículo
176 - Chavez-Gutierrez,L., Matta-Camacho,E., Osuna,J., Horjales,E., Joseph-Bravo,P., Maigret,B., Charli,J.L.. Homology modeling and site directed mutagenesis of pyroglutamyl peptidase II. Insights into omega versus aminopeptidase specificity in the M1 family.
Journal of Biological Chemistry,
281 (27),
18581-18590.
Artículo
177 - de Gortari,P., Uribe,R.M., Garcia-Vazquez,A., Aguilar-Valles,A., Martinez,A., Valdes,A., Charli,J.L., Fernandez-Guardiola,A., Joseph-Bravo,P.. Amygdala kindling differentially regulates the expression of the elements involved in TRH transmission.
Neurochemistry International,
48 (1),
31-42.
Internacional
178 - de Gortari,P., Joseph,P.. Neuroendocrine Regulation of Energy Metabolism. Molecular Endocrinology.
65-86,
Kerala, India: Research Signpost.
Internacional
179 - Joseph-Bravo,P., Cote-Velez,A., Perez-Martinez,L.. Integration of Neuroendocrine Signals that Regulate the Activity of Hypophysiotropic Peptides. Molecular Endocrinology.
1-24,
Kerala, India: Research Signpost.
Internacional
Artículo
181 - Aguilar-Valles,A., Sanchez,E., de Gortari,P., Balderas,I., Ramirez-Amaya,V., Bermudez-Rattoni,F., Joseph-Bravo,P.. Analysis of the Stress Response in Rats Trained in the Water-Maze: Differential Expression of Corticotropin-Releasing Hormone, CRH-R1, Glucocorticoid Receptors and Brain-Derived Neurotrophic Factor in Limbic Regions.
Neuroendocrinology,
82 (5-6),
306-319.
Artículo
182 - Chavez-Gutierrez,L., Bourdais,J., Aranda,G., Vargas,M.A., Matta-Camacho,E., Ducancel,F, Segovia,L., Joseph-Bravo,P., Charli,J.L.. A truncated isoform of pyroglutamyl aminopeptidase II produced by exon extension has dominant-negative activity.
Journal of Neurochemistry,
92 (4),
807-817.
Artículo
183 - Cote-Velez,A., Perez-Martinez,L., Diaz-Gallardo,M.Y., Perez-Monter,C., Carreon,A., Charli,J.L., Joseph-Bravo,P.. Dexamethasone repressed cAMP rapid upregulation of TRH gene transcription. Identification of a composite GRE and a CRE in TRH promoter.
Journal of Molecular Endocrinology,
34 (1),
177-197.
Artículo
184 - de Gortari,P., Romero,F., Cisneros,M., Joseph-Bravo,P.. Acute administration of alcohol modulates pyroglutamyl amino peptidase II activity and mRNA levels in rat limbic regions.
Neurochemistry International,
46 (4),
347-356.
Artículo
185 - de Gortari,P., Cisneros,M., Joseph-Bravo,P.. Chronic ethanol or glucose consumption alter TRH content and pyroglutamyl aminopeptidase II activity in rat limbic regions.
Regulatory Peptides,
127 (1-3),
141-150.
Artículo
186 - Cruz,R., Chavez-Gutierrez,L., Joseph-Bravo,P., Charli,J.L.. 3,3',5'-Triiodo-L-Thyronine Reduces Efficiency of mRNA Knockdown by Antisense Oligodeoxynucleotides: A Study with Pyroglutamyl Aminopeptidase II in Adenohypophysis .
Oligonucleotides,
14 (3),
176-190.
Artículo
187 - Pascual,I., Cisneros,M., Lage,J., Diaz,J, Joseph-Bravo,P., Charli,J.L., Chavez,M.A.. Isolation and purification of HcPI, a natural inhibitor of pyroglutamil aminopeptidase II (TRH-degrading ectoenzyme) from extracts of Hermodice carunculata (annelide: Polychaeta).
Revista Biologia,
18 (1),
38-49.
Artículo
188 - Pascual,I., Gil-Parrado,S., Cisneros,M., Joseph-Bravo,P., Diaz,J., Possani,L.D., Charli,J.L., Chavez,M.. Purification of a specific inhibitor of pyroglutamyl aminopeptidase II from the marine annelide Hermodice carunculata. In vivo effects in rodent brain.
International Journal of Biochemistry and Cell Biology,
36 (1),
138-152.
Editorial Material
189 - Joseph-Bravo,P.. Hypophysiotropic thyrotropin-releasing hormone neurons as transducers of energy homeostasis.
Endocrinology,
145 (11),
4813-4815.
Artículo
190 - de Gortari,P., Cisneros,M., Medellin,M.A., Joseph-Bravo,P.. Chronic ingestion of ethanol or glucose solutions affects hypothalamic and limbic TRH metabolism in dams and their pups.
Neurochemistry International,
41 (4),
237-249.
Artículo
191 - Joseph-Bravo,P., Perez-Martinez,L., Lezama,L., Morales-Chapa,C., Charli,J.L.. An improved method for the expression of TRH in serum-supplemented primary cultures of fetal hypothalamic cells.
Brain Research Protocols,
9 (2),
93-104.
Artículo
192 - Vargas,M.A., Uribe,R.M., Cisneros,M., Romero,F., Gonzalez,S., Joseph-Bravo,P., Charli,J.L.. Thyrotropin-releasing hormone regulates the diurnal variation of pyroglutamyl aminopeptidase II activity in the male rat adenohypophysis.
European Journal of Endocrinology,
147 (3),
363-369.
Artículo
193 - Vargas,M.A., Cisneros,M., Joseph-Bravo,P., Charli,J.L.. Thyrotropin-releasing hormone-induced down-regulation of pyroglutamyl aminopeptidase II activity involves L-type calcium channels and cam kinase activities in cultures of adenohypophyseal cells.
Journal of Neuroendocrinology,
14 (3),
184-193.
Artículo
194 - Baeza,M.A., Ponce,G., Joseph-Bravo,P., Charli,J.L.. Rapid down regulation of pyroglutamyl peptidase II activity by arachidonic acid in primary cultures of adenohypophyseal cells.
Life Sciences,
68 (17),
2051-2060.
Artículo
195 - Guerra-Crespo,M., Ubieta,R., Joseph-Bravo,P., Charli,J.L., Perez-Martinez,L.. BDNF increases the early expression of TRH mRNA in fetal TrkB+ hypothalamic neurons in primary culture.
European Journal of Neuroscience,
14 (3),
483-494.
Artículo
196 - Perez-Martinez,L., Charli,J., Joseph-Bravo,P.. Development of pro-TRH gene expression in primary cultures of fetal hypothalamic cells.
Developmental Brain Research,
130 (1),
73-81.
Artículo
197 - Sanchez,E., Uribe,R.M., Corkidi,G., Zoeller,R.T., Cisneros,M., Zacarias,M., Morales-Chapa,C., Charli,J.L., Joseph-Bravo,P.. Differential Responses of Thyrotropin-Releasing Hormone (TRH) Neurons to Cold Exposure or Suckling Indicate Functional Heterogeneity of the TRH System in the Paraventricular Nucleus of the Rat Hypothalamus.
Neuroendocrinology,
74 (6),
407-422.
Artículo
198 - Bourdais,J., Romero,F., Uriostegui,B., Cisneros,M., Joseph-Bravo,P., Charli,J.L.. [3-Me-His(2)]-TRH combined with dopamine withdrawal rapidly and transiently increases pyroglutamyl aminopeptidase II activity in primary cultures of adenohypophyseal cells.
Neuropeptides,
34 (2),
83-88.
Artículo
199 - de Gortari,P., Gonzalez-Alzati,M.E., Cisneros,M., Joseph-Bravo,P.. Effect of fasting on the content of thyrotropin-releasing hormone and its mRNA in the central nervous system and pyroglutamyl peptidase II activity in the anterior pituitary of post-weaned and adult rats.
Nutritional Neuroscience,
3 (4),
255-265.
Revisión
200 - de Gortari,P., Mendez,M., Rodriguez-Keller,I., Perez-Martinez,L., Joseph-Bravob,P.. Acute ethanol administration induces changes in TRH and proenkephalin expression in hypothalamic and limbic regions of rat brain.
Neurochemistry International,
37 (5-6),
483-496.
Artículo
201 - Niquet,J., Perez-Martinez,L., Guerra,M., Grouselle,D., Joseph-Bravo,P., Charli,J.. Extracellular matrix proteins increase the expression of pro-TRH and pro-protein convertase PC1 in fetal hypothalamic neurons in vitro.
Developmental Brain Research,
120 (1),
49-56.
Artículo
202 - Vargas,M.A., Cisneros,M., Joseph-Bravo,P., Charli,J.L.. Regulation of adenohypophyseal pyroglutamyl aminopeptidase II activity by thyrotropin-releasing hormone and phorbol esters.
Endocrine,
13 (3),
267-272.
Artículo
203 - Mendez,M., Cisneros,M., Baez,A., Joseph-Bravo,P., Charli,J.L.. Three TRH-like molecules are released from rat hypothalamus in vitro.
Neurochemical Research,
24 (7),
815-823.
Artículo
204 - Perez-Martinez,L., Uribe,R.M., Sanchez,E., Carreon-Rodriguez,A., Chavez,L., Zacarias,M., Joseph-Bravo,P., Charli,J.L.. Regulation of TRH biosynthesis in the paraventricular nucleus of rodent hypothalamus.
Current topics in neurochemistry,
2,
79-88.
Artículo; Actas Paper
205 - Charli,J.L., Vargas,M.A., Cisneros,M., de Gortari,P., Baeza,M.A., Jasso,P., Bourdais,J., Perez,L., Uribe,R.M., Joseph-Bravo,P.. TRH inactivation in the extracellular compartment: role of pyroglutamyl peptidase II.
Neurobiology (Bp.),
6 (1),
45-57.
Artículo
206 - de Gortari,P., Joseph-Bravo,P., Monroy-Ruiz,J., Martinez,A., Cisneros,M., Fernandez-Guardiola,A.. Brain thyrotropin-releasing hormone content varies through amygdaloid kindling development according to afterdischarge frequency and propagation.
Epilepsia,
39 (8),
897-903.
Revisión
207 - Joseph-Bravo,P., Uribe,R.M., Vargas,M.A., Perez-Martinez,L., Zoeller,T., Charli,J.L.. Multifactorial modulation of TRH metabolism.
Cellular & Molecular Neurobiology,
18 (2),
231-247.
Artículo
208 - Perez-Martinez,L., Carreon-Rodriguez,A., Gonzalez-Alzati,M.E., Morales,C., Charli,J.L., Joseph-Bravo,P.. Dexamethasone rapidly regulates TRH mRNA levels in hypothalamic cell cultures: interaction with the cAMP pathway.
Neuroendocrinology,
68 (5),
345-354.
Artículo
209 - Vargas,M.A., Bourdais,J., Sanchez,S., Uriostegui,B., Moreno,E., Joseph-Bravo,P., Charli,J.L.. Multiple hypothalamic factors regulate pyroglutamyl peptidase II in cultures of adenohypophyseal cells: role of the cAMP pathway.
Journal of Neuroendocrinology,
10 (3),
199-206.
Artículo
210 - Sanchez,E., Charli,J.L., Morales,C., Corkidi,G., Seidah,N.G., Joseph-Bravo,P., Uribe,R.M.. Expression of the proprotein convertases PC1 and PC2 mRNAs in thyrotropin releasing hormone neurons of the rat paraventricular nucleus of hypothalamus.
Brain Research,
761 (1),
77-86.
Artículo
211 - de Gortari,P., Fernandez-Guardiola,A., Martinez,A., Cisneros,M., Joseph-Bravo,P.. Changes in TRH and its degrading enzyme pyroglutamyl peptidase II, during the development of amygdaloid kindling.
Brain Research,
679 (1),
144-150.
Artículo
212 - Uribe,R.M., Joseph-Bravo,P., Charli,J.L.. Pups removal enhances thyrotropin-releasing hormone mRNA in the hypothalamic paraventricular nucleus.
European Journal of Endocrinology,
133 (3),
354-360.
Artículo
213 - Uribe,R.M., Perez-Martinez,L., Covarrubias,M.D., Gomez,O., Covarrubias,L., Charli,J.L., Joseph-Bravo,P.. Phorbol ester or cAMP enhance thyrotropin-releasing hormone mRNA in primary cultures of hypothalamic cells.
Neuroscience Letters,
201 (1),
41-44.
Nacional
214 - Joseph-Bravo,P.. Choques, transtornos y otras caídas. Stress, dolor y p?ptidos. Memoria del Curso Explorando el Cerebro.
35-37,
Mexico,D.F..
Note
215 - Charli,J.L., Cruz,C., Redondo,J.L., Guerra,C., Joseph-Bravo,P.. Homologous conditioned medium enhances expression of TRH in hypothalamic neurons in primary culture.
Developmental Brain Research,
89 (1),
155-160.
Artículo
216 - Covarrubias,L., Redondo,J.L., Vargas,M.A., Uribe,R.M., Mendez,M., Joseph-Bravo,P., Charli,J.L.. In vitro TRH release from hypothalamus slices varies during the diurnal cycle.
Neurochemical Research,
19 (7),
845-850.
Carta
Artículo
218 - Joseph-Bravo,P., Fresan,M., Cisneros,M., Vargas,M.A., Charli,J.L.. Pyroglutamyl peptidase II activity is not in the processes of bulbospinal TRHergic neurons.
Neuroscience Letters,
178 (2),
243-246.
Artículo
219 - Uribe,R.M., Joseph-Bravo,P., Ponce,G., Cisneros,M., Aceves,C., Charli,J.L.. Influence of thyroid status on TRH metabolism in rat olfactory bulb.
Peptides,
15 (3),
435-439.
Artículo
220 - Vargas,M.A., Joseph-Bravo,P., Charli,J.L.. Thyrotropin-releasing hormone downregulates pyroglutamyl peptidase II activity in adenohypophyseal cells.
Neuroendocrinology,
60 (3),
323-330.
Artículo
221 - Brakch,N., Boileau,G., Simonetti,M., Nault,C., Joseph-Bravo,P., Rholam,M., Cohen,P.. Prosomatostatin processing in Neuro2A cells. Role of beta-turn structure in the vicinity of the Arg-Lys cleavage site.
European Journal of Biochemistry,
216 (1),
39-47.
*
Artículo
222 - Uribe,R.M., Redondo,J.L., Charli,J.L., Joseph-Bravo,P.. Suckling and cold stress rapidly and transiently increase TRH mRNA in the paraventricular nucleus.
Neuroendocrinology,
58 (1),
140-145.
Note
223 - Mendez,M., Moran,J., Wilk,S., Joseph-Bravo,P., Charli,J.L.. Assessment of the role of TRH in the release of [3H]-dopamine from rat nucleus accumbens-lateral septum slices.
Brain Research Bulletin,
31 (5),
621-625.
Artículo
224 - Vargas,M.A., Cisneros,M., Herrera,J., Joseph-Bravo,P., Charli,J.L.. Regional distribution of pyroglutamyl peptidase II in rabbit brain, spinal cord, and organs.
Peptides,
13 (2),
255-260.
Note
225 - Vargas,M.A., Herrera,J., Uribe,R.M., Charli,J.L., Joseph-Bravo,P.. Ontogenesis of pyroglutamyl peptidase II activity in rat brain, adenohypophysis and pancreas.
Developmental Brain Research,
66 (2),
251-256.
Artículo
226 - Cruz,C., Charli,J.L., Vargas,M.A., Joseph-Bravo,P.. Neuronal localization of pyroglutamate aminopeptidase II in primary cultures of fetal mouse brain.
Journal of Neurochemistry,
56 (5),
1594-1601.
Artículo
227 - Lepage-Lezin,A., Joseph-Bravo,P., Devilliers,G., Benedetti,L., Launay,J.M., Gomez,S., Cohen,P.. Prosomatostatin is processed in the Golgi apparatus of rat neural cells.
Journal of Biological Chemistry,
266 (3),
1679-1688.
*
Artículo
228 - Uribe,R.M., Joseph-Bravo,P., Pasten,J., Ponce,G., Mendez,M., Covarrubias,L., Charli,J.L.. Some events of thyrotropin-releasing hormone metabolism are regulated in lactating and cycling rats.
Neuroendocrinology,
54 (5),
493-498.
Artículo
229 - Mendez,M., Cruz,C., Joseph-Bravo,P., Wilk,S., Charli,J.L.. Evaluation of the role of prolyl endopeptidase and pyroglutamyl peptidase I in the metabolism of LHRH and TRH in brain.
Neuropeptides,
17 (2),
55-62.
Note
230 - Fuchs,L.Y., Ovando,C., Joseph,P., Soberon,X., Charli,J.L.. Repetitive DNA sequence from the crayfish Procambarus clarkii.
Nucleic Acids Research,
18 (6),
1650.
Artículo
231 - Charli,J.L., Mendez,M., Vargas,M.A., Cisneros,M., Assai,M., Joseph-Bravo,P., Wilk,S.. Pyroglutamyl peptidase II inhibition specifically increases recovery of TRH released from rat brain slices.
Neuropeptides,
14 (3),
191-196.
Artículo
232 - Charli,J.L., Cruz,C., Ponce,G., Vargas,M.A., Mendez,M., Cisneros,M., Pasten,J., Joseph-Bravo,P.. Physiological relevance of pyroglutamate aminopeptidase II.
Annals of the New York Academy of Sciences,
553,
563-564.
Artículo
233 - Covarrubias,L., Uribe,R.M., Mendez,M., Charli,J.L., Joseph-Bravo,P.. Hypothalamic TRH mRNA regulation under different physiological conditions.
Annals of the New York Academy of Sciences,
553,
476-478.
Artículo
234 - Charli,J.L., Cruz,C., Vargas,M., Joseph-Bravo,P.. The narrow specificity pyroglutamate aminopeptidase degrading TRH in brain is an ectoenzyme.
Neurochemistry International,
13,
237-242.
Artículo
235 - Covarrubias,L., Uribe,R.M., Mendez,M., Charli,J.L., Joseph-Bravo,P.. Neuronal TRH synthesis: developmental and circadian TRH mRNA levels.
Biochemical and Biophysical Research Communications,
151 (1),
615-622.
Note
236 - Ponce,G., Charli,J.L., Pasten,J.A., Aceves,C., Joseph-Bravo,P.. Tissue-specific regulation of pyroglutamate aminopeptidase II activity by thyroid hormones.
Neuroendocrinology,
48 (2),
211-213.
Artículo
237 - Charli,J.L., Mendez,M., Joseph-Bravo,P., Wilk,S.. Specific inhibitors of pyroglutamyl peptidase I and prolyl endopeptidase do not change the in vitro release of TRH or its content in rodent brain.
Neuropeptides,
9 (4),
373-378.
Artículo
238 - Mendez,M., Joseph-Bravo,P., Cisneros,M., Vargas,M.A., Charli,J.L.. Regional distribution of in vitro release of thyrotropin releasing hormone in rat brain.
Peptides,
8 (2),
291-298.
Artículo
239 - Saavedra,R., Bravo,P.J., Charli,J.L., Herion,P.. Characterization of high affinity monoclonal antibodies against the luteinizing hormone-releasing hormone.
Hybridoma,
6 (6),
663-672.
Artículo
240 - Vargas,M., Mendez,M., Cisneros,M., Joseph-Bravo,P., Charli,J.L.. Regional distribution of the membrane-bound pyroglutamate amino peptidase-degrading thyrotropin-releasing hormone in rat brain.
Neuroscience Letters,
79 (3),
311-314.
Artículo
241 - Cohen,S., Charli,J.L., Diaz de Leon,L., Millar,R.P., Arimura,A., Morrison,M.R., Joseph-Bravo,P.. Attempts to immunoprecipitate the LHRH precursor synthesized in cell free systems.
Brain Research Bulletin,
16 (3),
309-314.
Artículo
242 - Torres,H., Charli,J.L., Vargas,M.A., Gonzalez-Noriega,A., Joseph-Bravo,P.. Subcellular distribution of the enzymes degrading Thyrotropin releasing hormone and metabolites in rat brain.
Neurochemistry International,
9,
103-110.
Artículo
243 - Garat,B., Miranda,J., Charli,J.L., Joseph-Bravo,P.. Presence of a membrane bound pyroglutamyl amino peptidase degrading thyrotropin releasing hormone in rat brain.
Neuropeptides,
6 (1),
27-40.
Artículo
244 - Charli,J.L., Ponce,G., McKelvy,J.F., Joseph-Bravo,P.. Accumulation of thyrotropin releasing hormone by rat hypothalamic slices.
Journal of Neurochemistry,
42 (4),
981-986.
Memoria in extenso
245 - Charli,J.L., Garat,B., Martinez-Escalera,G., Ponce,G., Miranda,J., Joseph-Bravo,P.. METABOLISM OF THYROTROPIN RELEASING HORMONE AND ITS POSSIBLE RELEVANCE TO PROLACTIN SECRETION. Prolactin Secretion: a Multidisciplinary Approach.
239-248,
Orlando: Academic Press.
Nacional
246 - Charli,J.L., Ponce,G., Torres,H., Garat,B., Barquin,N., Bravo,P.J.. [Cellular biochemistry of hypophysiotropic peptides. II. Liberation, action and inactivation].
Boletin de estudios medicos y biologicos,
32 (7-8 Suppl 1),
243-252.
Nacional
247 - Joseph-Bravo,P., Theleen,M., de Gortari,P., Shapiro,E., Redondo,J.L., Briones,M., Merchant,H., Charli,J.L.. [Biochemistry of hypophysiotropic peptides. I. Biosynthesis and its regulation].
Boletin de estudios medicos y biologicos,
32 (7-8 Suppl 1),
233-241.
Artículo
248 - Pacheco,M.F., McKelvy,J.F., Woodward,D.J., Loudes,C., Joseph-Bravo,P., Krulich,L., Griffin,W.S.. TRH in the rat cerebellum: I. Distribution and concentration.
Peptides,
2 (3),
277-282.
*
Artículo
249 - Joseph-Bravo,P., Charli,J.L., Sherman,T., Boyer,H., Bolivar,F., McKelvy,J.F.. Identification of a putative hypothalamic mRNA coding for somatostatin and of its product in cell-free translation.
Biochemical and Biophysical Research Communications,
94 (3),
1004-1012.
*
Nacional
250 - Charli,J.L., Joseph-Bravo,P., Robert,M.. Use of synthetic oligonucleotides for identification of messenger RNA for somatostatin.
Boletin de estudios medicos y biologicos,
31 (3-4),
220-221.
*
Artículo
251 - Joseph-Bravo,P., Loudes,C., Charli,J.L., Kordon,C.. Subcellular distribution of brain peptidases degrading luteinizing hormone releasing hormone (LHRH) and thyrotropin releasing hormone (TRH).
Brain Research,
166 (2),
321-329.
*
Artículo
252 - Joseph-Bravo,P., Charli,J.L., Palacios,J.M., Kordon,C.. Effect of neurotransmitters on the in vitro release of immunoreactive thyrotropin-releasing hormone from rat mediobasal hypothalamus.
Endocrinology,
104 (3),
801-806.
*
Artículo
253 - Lin,C., Joseph-Bravo,P., Sherman,T., Chan,L., McKelvy,J.F.. Cell-free synthesis of putative neurophysin precursors from rat and mouse hypothalamic poly (A)-RNA.
Biochemical and Biophysical Research Communications,
89 (3),
943-950.
*
Memoria in extenso
254 - Kordon,C., Enjalbert,A., Hery,M., Joseph-Bravo,P., Rotsztjen,W., Ruberg.M.. Role of neurotransmitters in the control of adenohypophyseal secretion. Handbook of the hypothalamus.
253-306,
2,
New York.
*
Artículo
255 - Loudes,C., Joseph-Bravo,P., Leblanc,P., Kordon,C.. Specific activity of LHRH and TRH degrading enzymes in various tissues of normal and castrated male rats.
Biochemical and Biophysical Research Communications,
83 (3),
921-926.
*
Note
256 - Charli,J.L., Joseph-Bravo,P., Palacios,J.M., Kordon,C.. Histamine-induced release of thyrotropin releasing hormone from hypothalamic slices.
European Journal of Pharmacology,
52 (3-4),
401-403.
*
Artículo
257 - Joseph-Bravo,P.I., Findley,M., Newberne,P.M.. Some interactions of light, riboflavin, and aflatoxin B1 in vivo and in vitro.
Journal of Toxicology and Environmental Health,
1 (3),
353-376.
*
258 - Joseph-Bravo, Patricia. Efecto de la melatonina sobre el metabolismo de aminas biogenicas en sistema nervioso central .
Facultad de Quimica,
Quimico,
UNAM.