Dra. Rita Restano Cassulini
Investigadora Posdoctoral SECIHTI
Nivel I del SNII
- Activos
- Graduados
-
Estancia Temporal
1 - Gonzalez Espinoza, Cindi Monserrat (2025). Expresión de toxinas de alacrán en células de mamíferos.
Instituto de Investigación en Ciencias Básicas y Aplicadas,
Licenciado en Ciencias Área Terminal en Bioquímica y Biología Molecular,
UAEM.
*
Asesor: Restano Cassulini, Rita
2 - Quevedo Zamora,Jéssica Sarahí (2013). Establecimiento y caracterización de una línea celular que exprese de manera estable y constitutiva el canal de sodio hNav1.7.
Ingeniero en Biotecnología,
Universidad Politécnica del Estado de Morelos.
*
Asesor: Restano Cassulini,Rita
* Indica publicación con otra institución de adscripción
Total de publicaciones: 50
- Tipo
- Fecha
Artículo
3 - Montero-Dominguez,P.A., Restano-Cassulini,R., Magana-Avila,L.C., Almanza,A., Mercado,F., Corzo,G. (2025). Design of antinociceptive peptide by grafting domains between scorpion B -neurotoxins.
Bioorganic Chemistry,
162,
108592.
Artículo
Artículo
5 - Valdez-Velazquez,L.L., Olamendi-Portugal,T., Restano-Cassulini,R., Riano-Umbarila,L., Jimenez-Vargas,J.M., Zamudio,F., Salazar-Monge,H., Becerril,B., Possani,L.D. (2025). Beta Toxins Isolated from the Scorpion Centruroides hirsutipalpus (Scorpiones; Buthidae) Affect the Function of Sodium Channels of Mammals.
Toxins (Basel),
17 (12),
584.
Artículo
6 - Restano-Cassulini,R., Olamendi-Portugal,T., Riano-Umbarila,L., Zamudio,F.Z., Delgado-Prudencio,G., Becerril,B., Possani,L.D. (2024). Characterization of Sodium Channel Peptides Obtained from the Venom of the Scorpion Centruroides bonito.
Toxins (Basel),
16 (3),
125.
Artículo
7 - Valencia-Martinez,H., Olamendi-Portugal,T., Restano-Cassulini,R., Serrano-Posada,H., Zamudio,F., Possani,L.D., Riano-Umbarila,L., Becerril,B. (2022). Characterization of Four Medically Important Toxins from Centruroides huichol Scorpion Venom and Its Neutralization by a Single Recombinant Antibody Fragment.
Toxins,
14 (6),
369.
Artículo
8 - Alamilla,J., Jimenez-Vargas,J.M., Galvan-Hernandez,A.R., Reyes-Mendez,M.E., Bermudez-Guzman,M.J., Restano-Cassulini,R., Olamendi-Portugal,T., Zamudio,F.Z., Possani,L.D., Valdez-Velazquez,L.L. (2021). Toxin Ct1a, from venom of Centruroides tecomanus, modifies the spontaneous firing frequency of neurons in the suprachiasmatic nucleus.
Toxicon,
197,
114-125.
Artículo
9 - Beltran-Vidal,J., Carcamo-Noriega,E., Pastor,N., Zamudio-Zuniga,F., Guerrero-Vargas,J.A., Castano,S., Possani,L.D., Restano-Cassulini,R. (2021). Colombian Scorpion Centruroides margaritatus: Purification and Characterization of a Gamma Potassium Toxin with Full-Block Activity on the hERG1 Channel.
Toxins (Basel),
13 (6),
407.
Artículo
10 - Benard-Valle,M., Neri-Castro,E.E., Yanez-Mendoza,M.F., Lomonte,B., Olvera,A., Zamudio,F., Restano-Cassulini,R., Possani,L.D., Jimenez-Ferrer,E., Alagon,A. (2020). Functional, proteomic and transcriptomic characterization of the venom from Micrurus browni browni: Identification of the first lethal multimeric neurotoxin in coral snake venom.
Journal of Proteomics,
225,
103863.
Artículo
11 - Gomez-Ramirez,I.V., Riano-Umbarila,L., Olamendi-Portugal,T., Restano-Cassulini,R., Possani,L.D., Becerril,B. (2020). Biochemical, electrophysiological and immunological characterization of the venom from Centruroides baergi, a new scorpion species of medical importance in Mexico.
Toxicon,
184,
10-18.
Artículo
12 - Mourao,C.B.F., Brand,G.D., Fernandes,J.P.C., Prates,M.V., Bloch,C., Barbosa,J.A.R.G., Freitas,S.M., Restano-Cassulini,R., Possani,L.D., Schwartz,E.F. (2020). Head-to-Tail Cyclization after Interaction with Trypsin: A Scorpion Venom Peptide that Resembles Plant Cyclotides.
Journal of Medicinal Chemistry,
63 (17),
9500?951.
Artículo
13 - Batista, C.V.F., Martins, J.G., Restano-Cassulini, R., Coronas, F.I.V., Zamudio, F.Z., Procopio, R., Possani, L.D. (2018). Venom characterization of the Amazonian scorpion Tityus metuendus.
Toxicon,
143,
51-58.
Artículo
14 - Carcamo-Noriega, E.N., Olamendi-Portugal, T., Restano-Cassulini, R., Rowe, A., Uribe-Romero, S.J., Becerril, B., Possani, L.D. (2018). Intraspecific variation of Centruroides sculpturatus scorpion venom from two regions of Arizona.
Archives of Biochemistry and Biophysics,
638,
52-57.
Artículo
15 - Guerrero-Garzon, J.F., Benard-Valle, M., Restano-Cassulini, R., Zamudio, F., Corzo, G., Alagon, A., Olvera-Rodriguez, A. (2018). Cloning and sequencing of three-finger toxins from the venom glands of four Micrurus species from Mexico and heterologous expression of an alpha-neurotoxin from Micrurus diastema.
Biochimie,
147,
114-121.
Artículo
16 - Olamendi-Portugal, T., Batista, C.V.F., Pedraza-Escalona, M., Restano-Cassulini, R., Zamudio, F.Z., Benard-Valle, M., de Roodt, A.R., Possani, L.D. (2018). New insights into the proteomic characterization of the coral snake Micrurus pyrrhocryptus venom.
Toxicon,
153,
23-31.
Artículo
17 - Valdez-Velazquez, L.L., Olamendi-Portugal, T., Restano-Cassulini, R., Zamudio, F.Z., Possani, L.D. (2018). Mass fingerprinting and electrophysiological analysis of the venom from the scorpion Centruroides hirsutipalpus (Scorpiones: Buthidae).
Journal of Venomous Animals and Toxins Including Tropical Diseases,
24,
17.
Artículo
18 - Garcia-Garcia, F., Corrales-Garcia, L.L., Olamendi-Portugal, T., Restano-Cassulini, R., Vega, R., Vega, M., Ortiz, E., Sandoval-Lopez, G., Soto, E., Corzo, G. (2017). Identification, chemical synthesis and heterologous expression of an antinociceptive peptide from the veined tree frog Trachycephalus typhonius.
Process Biochemistry,
62,
205-214.
Artículo
Artículo
20 - Restano-Cassulini, R., Garcia, W., Paniagua-Solis, J.F., Possani, L.D. (2017). Antivenom Evaluation by Electrophysiological Analysis.
Toxins (Basel),
9 (3),
74.
Artículo
21 - Coronas,F.I., Diego-Garcia,E., Restano-Cassulini,R., de Roodt,A.R., Possani,L.D. (2015). Biochemical and physiological characterization of a new Na-channel specific peptide from the venom of the Argentinean scorpion Tityus trivittatus.
Peptides,
68,
11-16.
Artículo
22 - Gonzalez-Morales,L., Pedraza-Escalona,M., Diego-Garcia,E., Restano-Cassulini,R., Batista,C.V., Gutierrez,M.C., Possani,L.D. (2014). Proteomic characterization of the venom and transcriptomic analysis of the venomous gland from the Mexican centipede Scolopendra viridis.
Journal of Proteomics,
111,
224-237.
Artículo
23 - Luna-Ramirez,K., Bartok,A., Restano-Cassulini,R., Quintero-Hernandez,V., Coronas,F., Christensen,J., Wright,C.E., Panyi,G., Possani,L.D. (2014). Structure, Molecular Modeling and Function of the First Potassium Channel Blocker, Urotoxin, Isolated from the Venom of the Australian Scorpion Urodacus Yaschenkoi.
Molecular Pharmacology,
86 (1),
28-41.
Artículo
24 - Pedraza-Escalona,M., Batista,C.V., Restano-Cassulini,R., Sandoval-Rios,M., Coronas,F.I., Possani,L.D. (2014). A proteomic analysis of the early secondary molecular effects caused by Cn2 scorpion toxin on neuroblastoma cells.
Journal of Proteomics,
111,
212-223.
Artículo
25 - Rodriguez-Ravelo,R., Restano-Cassulini,R., Zamudio,F.Z., Coronas,F.I.V., Espinosa-Lopez,G., Possani,L.D. (2014). A K+ channel blocking peptide from the Cuban scorpion Rhopalurus garridoi.
Peptides,
53,
42-47.
Artículo
26 - Vergara,I., Pedraza-Escalona,M., Paniagua,D., Restano-Cassulini,R., Zamudio,F., Batista,C.V., Possani,L.D., Alagon,A. (2014). Eastern coral snake Micrurus fulvius venom toxicity in mice is mainly determined by neurotoxic phospholipases A.
Journal of Proteomics,
105,
295-306.
Artículo
27 - Caliskan,F., Quintero-Hernandez,V., Restano-Cassulini,R., Coronas-Valderrama,F.I., Corzo,G., Possani,L.D. (2013). Molecular cloning and biochemical characterization of the first Na+-channel alpha-type toxin peptide (Acra4) from Androctonus crassicauda scorpion venom.
Biochimie,
95 (6),
1216-1222.
Artículo
28 - Mourao,C.B., Heghinian,M.D., Barbosa,E.A., Mari,F., Bloch,C.,Jr., Restano-Cassulini,R., Possani,L.D., Schwartz,E.F. (2013). Characterization of a novel peptide toxin from Acanthoscurria paulensis spider venom: a distinct cysteine assignment into the HWTX-II family.
Biochemistry,
52 (14),
2440-2452.
Artículo
29 - Caliskan,F., Garcia,B.I., Coronas,F.I., Restano-Cassulini,R., Korkmaz,F., Sahin,Y., Corzo,G., Possani,L.D. (2012). Purification and cDNA cloning of a novel neurotoxic peptide (Acra3) from the scorpion Androctonus crassicauda.
Peptides,
37 (1),
106-112.
Artículo
30 - Caliskan,F., Quintero-Hernandez,V., Restano-Cassulini,R., Batista,C.V.F., Zamudio,F.Z., Coronas,F.I., Possani,L.D. (2012). Turkish scorpion Buthacus macrocentrus: General characterization of the venom and description of Bu1, a potent mammalian Na+-channel à-toxin.
Toxicon,
59 (3),
408-415.
Artículo
31 - Jimenez-Vargas,J.M., Restano-Cassulini,R., Possani,L.D. (2012). Interacting sites of scorpion toxin ErgTx1 with hERG1 K(+) channels.
Toxicon,
59 (6),
633-641.
Artículo
32 - Jimenez-Vargas,J.M., Restano-Cassulini,R., Possani,L.D. (2012). Toxin modulators and blockers of hERG K(+) channels.
Toxicon,
60 (4),
492-501.
Artículo
33 - Camargos,T.S., Restano-Cassulini,R., Possani,L.D., Peigneur,S., Tytgat,J., Schwartz,C.A., de Freitas,S.M., Schwartz,E.F. (2011). The new kappa-KTx 2.5 from the scorpion Opisthacanthus cayaporum.
Peptides,
32 (7),
1509-1517.
Artículo
Artículo
35 - Garcia-Gomez,B.I., Coronas,F.I., Restano-Cassulini,R., Rodriguez,R.R., Possani,L.D. (2011). Biochemical and molecular characterization of the venom from the Cuban scorpion Rhopalurus junceus.
Toxicon,
58 (1),
18-27.
Artículo; Actas Paper
36 - Jimenez-Vargas,J.M., Restano-Cassulini,R., Quintero-Hernandez,V., Gurrola,G.B., Possani,L.D. (2011). Recombinant expression of the toxic peptide ErgTx1 and role of Met35 on its stability and function.
Peptides,
32 (3),
560-567.
Artículo
37 - Redaelli,E., Restano-Cassulini,R., Fuentes-Silva,D., Clement,H., Schiavon,E., Zamudio,F.Z., Odell,G., Arcangeli,A., Clare,J.J., Alagon,A., Rodriguez de la Vega,R.C., Possani,L.D., Wanke,E. (2010). Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels.
Journal of Biological Chemistry,
285 (6),
4130-4142 .
Artículo
38 - Olamendi-Portugal,T., Batista,C.V., Restano-Cassulini,R., Pando,V., Villa-Hernandez,O., Zavaleta-Martinez-Vargas,A., Salas-Arruz,M.C., de la Vega RC, Becerril,B., Possani,L.D. (2008). Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: Novel toxins, their function and phylogeny.
Proteomics,
8 (9),
1919-1932.
Artículo
39 - Restano-Cassulini,R., Olamendi-Portugal,T., Zamudio,F., Becerril,B., Possani,L.D. (2008). Two Novel Ergtoxins, Blockers of K(+)-channels, Purified from the Mexican Scorpion Centruroides elegans elegans.
Neurochemical Research,
33 (8),
1525-1533.
Artículo
40 - Lopez-Vera,E., Aguilar,M.B., Schiavon,E., Marinzi,C., Ortiz,E., Restano-Cassulini,R., Batista,C.V.F., Possani,L.D., Heimer de la Cotera,E.P., Peri,F., Becerril,B., Wanke,E. (2007). Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors.
Febs Journal,
274 (15),
3972-3985.
Artículo
41 - Wanke,E., Restano-Cassulini,R. (2007). Toxins interacting with ether-a-go-go-related gene voltage-dependent potassium channels.
Toxicon,
49 (2),
239-248.
*
Artículo; Actas Paper
42 - Restano-Cassulini,R., Korolkova,Y.V., Diochot,S., Gurrola,G., Guasti,L., Possani,L., Lazdunski,M., Grishin,E., Arcangeli,A., Wanke,E. (2006). Species Diversity and Peptide Toxins Blocking Selectivity of ERG Subfamily K+ Channels in CNS.
Molecular Pharmacology,
69 (5),
1673-1683.
Artículo
43 - Schiavon,E., Sacco,T., Restano-Cassulini,R., Gurrola,G., Tempia,F., Possani,L.D., Wanke,E. (2006). Resurgent current and voltage sensor-trapping enhanced activation by a {beta}-scorpion toxin solely in nav1.6 channel: Significance in Mice Purkinje Neurons.
Journal of Biological Chemistry,
281 (29),
20326-20337.
Artículo
44 - Masi,A., Becchetti,A., Restano-Cassulini,R., Polvani,S., Hofmann,G., Buccoliero,A.M., Paglierani,M., Pollo,B., Taddei,G.L., Gallina,P., Di Lorenzo,N., Franceschetti,S., Wanke,E., Arcangeli,A. (2005). hERG1 channels are overexpressed in glioblastoma multiforme and modulate VEGF secretion in glioblastoma cell lines.
British Journal of Cancer,
93 (7),
781-792.
*
Artículo
45 - Orsini,F., Verotta,L., Lecchi,M., Restano-Cassulini,R., Curia,G., Redaelli,E., Wanke,E. (2004). Resveratrol Derivatives and Their Role as Potassium Channels Modulators.
Journal of Natural Products,
67 (3),
421-426.
*
Artículo
46 - D'Amico,M., Biagiotti,T., Fontana,L., Restano-Cassulini,R., Lasagna,N., Arcangeli,A., Wanke,E., Olivotto,M. (2003). A HERG current sustains a cardiac-type action potential in neuroblastoma S cells.
Biochemical and Biophysical Research Communications,
302 (1),
101-108.
*
Artículo
47 - Pimpinelli,F., Redaelli,E., Restano-Cassulini,R., Curia,G., Giacobini,P., Cariboni,A., Wanke,E., Bondiolotti,G.P., Piva,F., Maggi,R. (2003). Depolarization differentially affects the secretory and migratory properties of two cell lines of immortalized luteinizing hormone-releasing hormone (LHRH) neurons.
European Journal of Neuroscience,
18 (6),
1410-1418.
*
Artículo
48 - Becchetti,A., De Fusco,M., Crociani,O., Cherubini,A., Restano-Cassulini,R., Lecchi,M., Masi,A., Arcangeli,A., Casari,G., Wanke,E. (2002). The functional properties of the human ether-+ -go-go-like (HELK2) K+ channel.
European Journal of Neuroscience,
16 (3),
415-428.
*
Internacional in press
49 - Jimenez-Vargas,J.M., Cid-Uribe,J.I., Restano-Cassulini,R. (2026). Neotropical scorpion venom. The Biology of Neotropical Scorpions - From Taxonomy and Genetics to Ecology and Ethnobiology. .
Internacional
50 - Possani,L.D., Gurrola,G.B., Schwartz,E., Restano,R. (2011). Bioquimica y biologia molecular de los venenos de escorpiones de importancia medica en el continente americano. Emergencias por Animales Ponzonosos en las Americas .
147-180,
Mexico.
Internacional
51 - Rodriguez-de-la-Vega,R., Barraza,R., Restano,R., Possani,L.D. (2009). Toxins active on Herg channel: structure and function. Animal toxins: State of the Art. Perspectives in Health and Biotechnology .
193-204,
Belo Horizonte: EditoraUFMG.
Nacional divulgación
52 - Restano-Cassulini,R., Delgado-Prudencio,G., Gurrola-Briones,G. (2024). El veneno de alacrán: una mina de moléculas con potencial farmacológico.
Hypatia,
73,
32-33.
Internacional in press
53 - Jimenez-Vargas,J.M., Cid-Uribe,J.I., Restano-Cassulini,R.. Neotropical scorpion venom. The Biology of Neotropical Scorpions - From Taxonomy and Genetics to Ecology and Ethnobiology. .
Artículo
54 - Montero-Dominguez,P.A., Restano-Cassulini,R., Magana-Avila,L.C., Almanza,A., Mercado,F., Corzo,G.. Design of antinociceptive peptide by grafting domains between scorpion B -neurotoxins.
Bioorganic Chemistry,
162,
108592.
Artículo
55 - Olamendi-Portugal,T., Delgado-Prudencio,G., Restano-Cassulini,R., Zamudio,F.Z., Meneses-Romero,E.P., Becerril,B., Possani,L.D.. Isolation and Characterization of Three Lethal Toxins from the Mexican Scorpion Centruroides mascota.
Toxicon,
266,
108498.
Artículo
56 - Valdez-Velazquez,L.L., Olamendi-Portugal,T., Restano-Cassulini,R., Riano-Umbarila,L., Jimenez-Vargas,J.M., Zamudio,F., Salazar-Monge,H., Becerril,B., Possani,L.D.. Beta Toxins Isolated from the Scorpion Centruroides hirsutipalpus (Scorpiones; Buthidae) Affect the Function of Sodium Channels of Mammals.
Toxins (Basel),
17 (12),
584.
Artículo
57 - Restano-Cassulini,R., Olamendi-Portugal,T., Riano-Umbarila,L., Zamudio,F.Z., Delgado-Prudencio,G., Becerril,B., Possani,L.D.. Characterization of Sodium Channel Peptides Obtained from the Venom of the Scorpion Centruroides bonito.
Toxins (Basel),
16 (3),
125.
Nacional divulgación
Artículo
59 - Valencia-Martinez,H., Olamendi-Portugal,T., Restano-Cassulini,R., Serrano-Posada,H., Zamudio,F., Possani,L.D., Riano-Umbarila,L., Becerril,B.. Characterization of Four Medically Important Toxins from Centruroides huichol Scorpion Venom and Its Neutralization by a Single Recombinant Antibody Fragment.
Toxins,
14 (6),
369.
Artículo
60 - Alamilla,J., Jimenez-Vargas,J.M., Galvan-Hernandez,A.R., Reyes-Mendez,M.E., Bermudez-Guzman,M.J., Restano-Cassulini,R., Olamendi-Portugal,T., Zamudio,F.Z., Possani,L.D., Valdez-Velazquez,L.L.. Toxin Ct1a, from venom of Centruroides tecomanus, modifies the spontaneous firing frequency of neurons in the suprachiasmatic nucleus.
Toxicon,
197,
114-125.
Artículo
61 - Beltran-Vidal,J., Carcamo-Noriega,E., Pastor,N., Zamudio-Zuniga,F., Guerrero-Vargas,J.A., Castano,S., Possani,L.D., Restano-Cassulini,R.. Colombian Scorpion Centruroides margaritatus: Purification and Characterization of a Gamma Potassium Toxin with Full-Block Activity on the hERG1 Channel.
Toxins (Basel),
13 (6),
407.
Artículo
62 - Benard-Valle,M., Neri-Castro,E.E., Yanez-Mendoza,M.F., Lomonte,B., Olvera,A., Zamudio,F., Restano-Cassulini,R., Possani,L.D., Jimenez-Ferrer,E., Alagon,A.. Functional, proteomic and transcriptomic characterization of the venom from Micrurus browni browni: Identification of the first lethal multimeric neurotoxin in coral snake venom.
Journal of Proteomics,
225,
103863.
Artículo
63 - Gomez-Ramirez,I.V., Riano-Umbarila,L., Olamendi-Portugal,T., Restano-Cassulini,R., Possani,L.D., Becerril,B.. Biochemical, electrophysiological and immunological characterization of the venom from Centruroides baergi, a new scorpion species of medical importance in Mexico.
Toxicon,
184,
10-18.
Artículo
64 - Mourao,C.B.F., Brand,G.D., Fernandes,J.P.C., Prates,M.V., Bloch,C., Barbosa,J.A.R.G., Freitas,S.M., Restano-Cassulini,R., Possani,L.D., Schwartz,E.F.. Head-to-Tail Cyclization after Interaction with Trypsin: A Scorpion Venom Peptide that Resembles Plant Cyclotides.
Journal of Medicinal Chemistry,
63 (17),
9500?951.
Artículo
65 - Batista, C.V.F., Martins, J.G., Restano-Cassulini, R., Coronas, F.I.V., Zamudio, F.Z., Procopio, R., Possani, L.D.. Venom characterization of the Amazonian scorpion Tityus metuendus.
Toxicon,
143,
51-58.
Artículo
66 - Carcamo-Noriega, E.N., Olamendi-Portugal, T., Restano-Cassulini, R., Rowe, A., Uribe-Romero, S.J., Becerril, B., Possani, L.D.. Intraspecific variation of Centruroides sculpturatus scorpion venom from two regions of Arizona.
Archives of Biochemistry and Biophysics,
638,
52-57.
Artículo
67 - Guerrero-Garzon, J.F., Benard-Valle, M., Restano-Cassulini, R., Zamudio, F., Corzo, G., Alagon, A., Olvera-Rodriguez, A.. Cloning and sequencing of three-finger toxins from the venom glands of four Micrurus species from Mexico and heterologous expression of an alpha-neurotoxin from Micrurus diastema.
Biochimie,
147,
114-121.
Artículo
68 - Olamendi-Portugal, T., Batista, C.V.F., Pedraza-Escalona, M., Restano-Cassulini, R., Zamudio, F.Z., Benard-Valle, M., de Roodt, A.R., Possani, L.D.. New insights into the proteomic characterization of the coral snake Micrurus pyrrhocryptus venom.
Toxicon,
153,
23-31.
Artículo
69 - Valdez-Velazquez, L.L., Olamendi-Portugal, T., Restano-Cassulini, R., Zamudio, F.Z., Possani, L.D.. Mass fingerprinting and electrophysiological analysis of the venom from the scorpion Centruroides hirsutipalpus (Scorpiones: Buthidae).
Journal of Venomous Animals and Toxins Including Tropical Diseases,
24,
17.
Artículo
70 - Garcia-Garcia, F., Corrales-Garcia, L.L., Olamendi-Portugal, T., Restano-Cassulini, R., Vega, R., Vega, M., Ortiz, E., Sandoval-Lopez, G., Soto, E., Corzo, G.. Identification, chemical synthesis and heterologous expression of an antinociceptive peptide from the veined tree frog Trachycephalus typhonius.
Process Biochemistry,
62,
205-214.
Artículo
71 - Olamendi-Portugal, T., Restano-Cassulini, R., Riano-Umbarila, L., Becerril, B., Possani, L.D.. Functional and immuno-reactive characterization of a previously undescribed peptide from the venom of the scorpion centruroides limpidus.
Peptides,
87,
34-40.
Artículo
72 - Restano-Cassulini, R., Garcia, W., Paniagua-Solis, J.F., Possani, L.D.. Antivenom Evaluation by Electrophysiological Analysis.
Toxins (Basel),
9 (3),
74.
Artículo
Artículo
74 - Gonzalez-Morales,L., Pedraza-Escalona,M., Diego-Garcia,E., Restano-Cassulini,R., Batista,C.V., Gutierrez,M.C., Possani,L.D.. Proteomic characterization of the venom and transcriptomic analysis of the venomous gland from the Mexican centipede Scolopendra viridis.
Journal of Proteomics,
111,
224-237.
Artículo
75 - Luna-Ramirez,K., Bartok,A., Restano-Cassulini,R., Quintero-Hernandez,V., Coronas,F., Christensen,J., Wright,C.E., Panyi,G., Possani,L.D.. Structure, Molecular Modeling and Function of the First Potassium Channel Blocker, Urotoxin, Isolated from the Venom of the Australian Scorpion Urodacus Yaschenkoi.
Molecular Pharmacology,
86 (1),
28-41.
Artículo
76 - Pedraza-Escalona,M., Batista,C.V., Restano-Cassulini,R., Sandoval-Rios,M., Coronas,F.I., Possani,L.D.. A proteomic analysis of the early secondary molecular effects caused by Cn2 scorpion toxin on neuroblastoma cells.
Journal of Proteomics,
111,
212-223.
Artículo
77 - Rodriguez-Ravelo,R., Restano-Cassulini,R., Zamudio,F.Z., Coronas,F.I.V., Espinosa-Lopez,G., Possani,L.D.. A K+ channel blocking peptide from the Cuban scorpion Rhopalurus garridoi.
Peptides,
53,
42-47.
Artículo
78 - Vergara,I., Pedraza-Escalona,M., Paniagua,D., Restano-Cassulini,R., Zamudio,F., Batista,C.V., Possani,L.D., Alagon,A.. Eastern coral snake Micrurus fulvius venom toxicity in mice is mainly determined by neurotoxic phospholipases A.
Journal of Proteomics,
105,
295-306.
Artículo
79 - Caliskan,F., Quintero-Hernandez,V., Restano-Cassulini,R., Coronas-Valderrama,F.I., Corzo,G., Possani,L.D.. Molecular cloning and biochemical characterization of the first Na+-channel alpha-type toxin peptide (Acra4) from Androctonus crassicauda scorpion venom.
Biochimie,
95 (6),
1216-1222.
Artículo
80 - Mourao,C.B., Heghinian,M.D., Barbosa,E.A., Mari,F., Bloch,C.,Jr., Restano-Cassulini,R., Possani,L.D., Schwartz,E.F.. Characterization of a novel peptide toxin from Acanthoscurria paulensis spider venom: a distinct cysteine assignment into the HWTX-II family.
Biochemistry,
52 (14),
2440-2452.
Artículo
81 - Caliskan,F., Garcia,B.I., Coronas,F.I., Restano-Cassulini,R., Korkmaz,F., Sahin,Y., Corzo,G., Possani,L.D.. Purification and cDNA cloning of a novel neurotoxic peptide (Acra3) from the scorpion Androctonus crassicauda.
Peptides,
37 (1),
106-112.
Artículo
82 - Caliskan,F., Quintero-Hernandez,V., Restano-Cassulini,R., Batista,C.V.F., Zamudio,F.Z., Coronas,F.I., Possani,L.D.. Turkish scorpion Buthacus macrocentrus: General characterization of the venom and description of Bu1, a potent mammalian Na+-channel à-toxin.
Toxicon,
59 (3),
408-415.
Artículo
83 - Jimenez-Vargas,J.M., Restano-Cassulini,R., Possani,L.D.. Interacting sites of scorpion toxin ErgTx1 with hERG1 K(+) channels.
Toxicon,
59 (6),
633-641.
Artículo
84 - Jimenez-Vargas,J.M., Restano-Cassulini,R., Possani,L.D.. Toxin modulators and blockers of hERG K(+) channels.
Toxicon,
60 (4),
492-501.
Artículo
85 - Camargos,T.S., Restano-Cassulini,R., Possani,L.D., Peigneur,S., Tytgat,J., Schwartz,C.A., de Freitas,S.M., Schwartz,E.F.. The new kappa-KTx 2.5 from the scorpion Opisthacanthus cayaporum.
Peptides,
32 (7),
1509-1517.
Artículo
86 - Estrada,G., Restano-Cassulini,R., Ortiz,E., Possani,L.D., Corzo,G.. Addition of positive charges at the C-terminal peptide region of CssII; a mammalian scorpion peptide toxin; improves its affinity for sodium channels Nav1.6.
Peptides,
32 (1),
75-79 .
Artículo
87 - Garcia-Gomez,B.I., Coronas,F.I., Restano-Cassulini,R., Rodriguez,R.R., Possani,L.D.. Biochemical and molecular characterization of the venom from the Cuban scorpion Rhopalurus junceus.
Toxicon,
58 (1),
18-27.
Artículo; Actas Paper
88 - Jimenez-Vargas,J.M., Restano-Cassulini,R., Quintero-Hernandez,V., Gurrola,G.B., Possani,L.D.. Recombinant expression of the toxic peptide ErgTx1 and role of Met35 on its stability and function.
Peptides,
32 (3),
560-567.
Internacional
89 - Possani,L.D., Gurrola,G.B., Schwartz,E., Restano,R.. Bioquimica y biologia molecular de los venenos de escorpiones de importancia medica en el continente americano. Emergencias por Animales Ponzonosos en las Americas .
147-180,
Mexico.
Artículo
90 - Redaelli,E., Restano-Cassulini,R., Fuentes-Silva,D., Clement,H., Schiavon,E., Zamudio,F.Z., Odell,G., Arcangeli,A., Clare,J.J., Alagon,A., Rodriguez de la Vega,R.C., Possani,L.D., Wanke,E.. Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels.
Journal of Biological Chemistry,
285 (6),
4130-4142 .
Internacional
91 - Rodriguez-de-la-Vega,R., Barraza,R., Restano,R., Possani,L.D.. Toxins active on Herg channel: structure and function. Animal toxins: State of the Art. Perspectives in Health and Biotechnology .
193-204,
Belo Horizonte: EditoraUFMG.
Artículo
92 - Olamendi-Portugal,T., Batista,C.V., Restano-Cassulini,R., Pando,V., Villa-Hernandez,O., Zavaleta-Martinez-Vargas,A., Salas-Arruz,M.C., de la Vega RC, Becerril,B., Possani,L.D.. Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: Novel toxins, their function and phylogeny.
Proteomics,
8 (9),
1919-1932.
Artículo
93 - Restano-Cassulini,R., Olamendi-Portugal,T., Zamudio,F., Becerril,B., Possani,L.D.. Two Novel Ergtoxins, Blockers of K(+)-channels, Purified from the Mexican Scorpion Centruroides elegans elegans.
Neurochemical Research,
33 (8),
1525-1533.
Artículo
94 - Lopez-Vera,E., Aguilar,M.B., Schiavon,E., Marinzi,C., Ortiz,E., Restano-Cassulini,R., Batista,C.V.F., Possani,L.D., Heimer de la Cotera,E.P., Peri,F., Becerril,B., Wanke,E.. Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors.
Febs Journal,
274 (15),
3972-3985.
Artículo
95 - Wanke,E., Restano-Cassulini,R.. Toxins interacting with ether-a-go-go-related gene voltage-dependent potassium channels.
Toxicon,
49 (2),
239-248.
*
Artículo; Actas Paper
96 - Restano-Cassulini,R., Korolkova,Y.V., Diochot,S., Gurrola,G., Guasti,L., Possani,L., Lazdunski,M., Grishin,E., Arcangeli,A., Wanke,E.. Species Diversity and Peptide Toxins Blocking Selectivity of ERG Subfamily K+ Channels in CNS.
Molecular Pharmacology,
69 (5),
1673-1683.
Artículo
97 - Schiavon,E., Sacco,T., Restano-Cassulini,R., Gurrola,G., Tempia,F., Possani,L.D., Wanke,E.. Resurgent current and voltage sensor-trapping enhanced activation by a {beta}-scorpion toxin solely in nav1.6 channel: Significance in Mice Purkinje Neurons.
Journal of Biological Chemistry,
281 (29),
20326-20337.
Artículo
98 - Masi,A., Becchetti,A., Restano-Cassulini,R., Polvani,S., Hofmann,G., Buccoliero,A.M., Paglierani,M., Pollo,B., Taddei,G.L., Gallina,P., Di Lorenzo,N., Franceschetti,S., Wanke,E., Arcangeli,A.. hERG1 channels are overexpressed in glioblastoma multiforme and modulate VEGF secretion in glioblastoma cell lines.
British Journal of Cancer,
93 (7),
781-792.
*
Artículo
99 - Orsini,F., Verotta,L., Lecchi,M., Restano-Cassulini,R., Curia,G., Redaelli,E., Wanke,E.. Resveratrol Derivatives and Their Role as Potassium Channels Modulators.
Journal of Natural Products,
67 (3),
421-426.
*
Artículo
100 - D'Amico,M., Biagiotti,T., Fontana,L., Restano-Cassulini,R., Lasagna,N., Arcangeli,A., Wanke,E., Olivotto,M.. A HERG current sustains a cardiac-type action potential in neuroblastoma S cells.
Biochemical and Biophysical Research Communications,
302 (1),
101-108.
*
Artículo
101 - Pimpinelli,F., Redaelli,E., Restano-Cassulini,R., Curia,G., Giacobini,P., Cariboni,A., Wanke,E., Bondiolotti,G.P., Piva,F., Maggi,R.. Depolarization differentially affects the secretory and migratory properties of two cell lines of immortalized luteinizing hormone-releasing hormone (LHRH) neurons.
European Journal of Neuroscience,
18 (6),
1410-1418.
*
Artículo
102 - Becchetti,A., De Fusco,M., Crociani,O., Cherubini,A., Restano-Cassulini,R., Lecchi,M., Masi,A., Arcangeli,A., Casari,G., Wanke,E.. The functional properties of the human ether-+ -go-go-like (HELK2) K+ channel.
European Journal of Neuroscience,
16 (3),
415-428.
*