Dr. Ernesto Ortiz Suri
Técnico Académico Titular C Tiempo Completo
Bioinformática
Biología Molecular y Bioquímica de venenos de animales ponzoñosos
Biotecnología de anticuerpos terapéuticos y toxinología aplicada
Estructura, Función y Manipulación de Péptidos y Proteínas con función antimicrobiana
Número de registros: 1
- Vencidos
Vencidos
- Obtencion de un fragmento de anticuerpo vhh especifico contra la expansina del hongo basidiomiceto bjerkandera adusta, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2009
Nivel II del SNII
Doctorado, en Biotecnología, IBt-UNAM (1998)
Maestría, en Bioquímica, Universidad estatal de Moscu M.V. Lononosov, Fac. de Biología
Licenciatura, Biología, Universidad Estatal de Moscu M.V. Lomonosov, Fac. de Biología
- Graduados
Graduados
1 - Delgado Prudencio, Gustavo (2021). El sistema enzimático dual de a-amidación en las glándulas de veneno de escorpión .
Instituto de Biotecnologia,
Doctorado en Bioquímicas,
UNAM.
Asesor: Ortiz Suri, Ernesto
2 - Garcia Montelongo, Monica (2015). Despliegue en fagos de variantes del amino terminal de la toxina CSS2.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Ortiz Suri, Ernesto
3 - Amaro Estrada, Itzel (2007). Construccion y caracterizacion de una biblioteca de fragmentos variables de anticuerpos de cadena pesada de Lama glama desplegados en fagos .
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Ortiz Suri, Ernesto
Total de publicaciones: 58
- Tipo
- Fecha
Tipo
Artículo Short communication
4 - Delgado-Prudencio,G., Becerril,B., Possani,L.D., Ortiz,E. (2025). New proposal for the systematic nomenclature of scorpion peptides.
Toxicon,
253,
108192.
Artículo
5 - Monteiro,I.S., Araujo,I.F.S., Camargos,T.S., Ortiz,E., Souza,A.C.B., Lima,J.D., Possani,L.D., Schwartz,E.F., Tibery,D.V. (2025). The First K(+)-Channel Blocker Described from Tityus fasciolatus Venom: The Purification, Molecular Cloning, and Functional Characterization of a-KTx4.9 (Tf5).
Toxins (Basel),
17 (2),
96.
Artículo
6 - Luna-Bulbarela,A., Romero-Gutierrez,M.T., Tinoco-Valencia,R., Ortiz,E., Martinez-Romero,M.E., Galindo,E., Serrano-Carreon,L. (2024). Response of Bacillus velezensis 83 to interaction with Colletotrichum gloeosporioides resembles a Greek phalanx-style formation: a stress resistant phenotype with antibiosis capacity.
Microbiological Research,
280,
127592.
Artículo
7 - Delgado-Prudencio,G., Cid-Uribe,J.I., Morales,J.A., Possani,L.D., Ortiz,E., Romero-Gutierrez,T. (2022). The Enzymatic Core of Scorpion Venoms.
Toxins,
14 (4),
248.
Artículo
8 - Okada,M., Ortiz,E. (2022). Viral vector-mediated expressions of venom peptides as novel gene therapy for anxiety and depression.
Medical Hypotheses,
166,
110910.
Internacional
56 - Garcia,F., Villegas,E., Ortiz,E., Corzo,G. (2015). Structural Diversity and Basic/Acidic Residue Balance of Active Cysteine-Rich Insecticidal Peptides from Spiders. Spider Venoms.
Toxinology,
1-20.
Internacional
57 - Chavez-Haro,A.L., Ortiz,E. (2014). Scorpionism and Dangerous Species of Mexico. Scorpion Venoms.
Toxinology,
201-213.
Internacional
58 - Rendon-Anaya,M., Camargos,T.S., Ortiz,E. (2014). Scorpion Venom Gland Transcriptomics. Scorpion Venoms.
Toxinology,
531-545,
Dordrect: Springer.
Internacional
59 - del Pozo-Yauner,L, Ortiz,E., Becerril,B. (2009). Diseases related to protein misfolding. Advances in Protein Physical Chemistry.
469-501,
Kerala: Research Signpost.
Nacional divulgación
60 - Quintero Rodriguez,E., Rueda Almazan,J.E., Ortiz Suri,E. (2024). El veneno del alacrán: mitos y realidades.
Hypatia,
71,
4-5.
61 - Ortiz Suri, Ernesto (1998). Moleculas de PNA en sistemas fluorescentes de deteccion por hibridacion en la discriminacion de alelos .
Instituto de Biotecnologia,
56, [10] paginas,
Doctorado en Biotecnologia,
UNAM.
Fecha
Artículo Short communication
62 - Delgado-Prudencio,G., Becerril,B., Possani,L.D., Ortiz,E.. New proposal for the systematic nomenclature of scorpion peptides.
Toxicon,
253,
108192.
Artículo
63 - Monteiro,I.S., Araujo,I.F.S., Camargos,T.S., Ortiz,E., Souza,A.C.B., Lima,J.D., Possani,L.D., Schwartz,E.F., Tibery,D.V.. The First K(+)-Channel Blocker Described from Tityus fasciolatus Venom: The Purification, Molecular Cloning, and Functional Characterization of a-KTx4.9 (Tf5).
Toxins (Basel),
17 (2),
96.
Artículo
64 - Luna-Bulbarela,A., Romero-Gutierrez,M.T., Tinoco-Valencia,R., Ortiz,E., Martinez-Romero,M.E., Galindo,E., Serrano-Carreon,L.. Response of Bacillus velezensis 83 to interaction with Colletotrichum gloeosporioides resembles a Greek phalanx-style formation: a stress resistant phenotype with antibiosis capacity.
Microbiological Research,
280,
127592.
Nacional divulgación
65 - Quintero Rodriguez,E., Rueda Almazan,J.E., Ortiz Suri,E.. El veneno del alacrán: mitos y realidades.
Hypatia,
71,
4-5.
Artículo
66 - Delgado-Prudencio,G., Cid-Uribe,J.I., Morales,J.A., Possani,L.D., Ortiz,E., Romero-Gutierrez,T.. The Enzymatic Core of Scorpion Venoms.
Toxins,
14 (4),
248.
Artículo
67 - Okada,M., Ortiz,E.. Viral vector-mediated expressions of venom peptides as novel gene therapy for anxiety and depression.
Medical Hypotheses,
166,
110910.
Artículo
68 - Okada,M., Ortiz,E.. Therapeutic potential of viral vectors that express venom peptides for neurological diseases.
Medical Hypotheses,
161,
110809.
Artículo
69 - Jimenez-Vargas,J.M., Ramirez-Carreto,S., Corzo,G., Possani,L.D., Becerril,B., Ortiz,E.. Structural and functional characterization of NDBP-4 family antimicrobial peptides from the scorpion Mesomexovis variegatus.
Peptides,
141,
170553.
Revision
70 - Santana,F.L., Estrada,K., Ortiz,E., Corzo,G.. Reptilian beta-defensins: expanding the repertoire of known crocodylian peptides.
Peptides,
136,
170473.
Revisión
71 - Cid-Uribe,J.I., Veytia-Bucheli,J.I., Romero-Gutierrez,T., Ortiz,E., Possani,L.D.. Scorpion venomics: a 2019 overview.
Expert Review of Proteomics,
17 (1),
67-83.
Artículo
72 - Bernaldez-Sarabia,J., Figueroa-Montiel,A., Duenas,S., Cervantes-Luevano,K., Beltran,J.A., Ortiz,E., Jimenez,S., Possani,L.D., Paniagua-Solis,J.F., Gonzalez-Canudas,J., Licea-Navarro,A.. The Diversified O-Superfamily in Californiconus californicus Presents a Conotoxin with Antimycobacterial Activity.
Toxins (Basel),
11 (2),
E128.
Artículo
73 - Carcamo-Noriega,E.N., Possani,L.D., Ortiz,E.. Venom content and toxicity regeneration after venom gland depletion by electrostimulation in the scorpion Centruroides limpidus.
Toxicon,
157,
87-92.
Artículo
74 - Cid-Uribe,J.I., Meneses,E.P., Batista,C.V.F., Ortiz,E., Possani,L.D.. Dissecting Toxicity: The Venom Gland Transcriptome and the Venom Proteome of the Highly Venomous Scorpion Centruroides limpidus (Karsch, 1879).
Toxins (Basel),
11 (5),
247.
Artículo
75 - Delgado-Prudencio, G., Possani, L. D., Becerril, B., Ortiz, E.. The Dual alpha-Amidation System in Scorpion Venom Glands.
Toxins (Basel),
11 (7).
Artículo
76 - Okada,M., Ortiz,E., Corzo,G., Possani,L.D.. Pore-forming spider venom peptides show cytotoxicity to hyperpolarized cancer cells expressing K+ channels: A lentiviral vector approach.
PLoS ONE,
14 (4),
e0215391.
Artículo
77 - Santibanez-Lopez,C.E., Graham,M.R., Sharma,P.P., Ortiz,E., Possani,L.D.. Hadrurid Scorpion Toxins: Evolutionary Conservation and Selective Pressures.
Toxins (Basel),
11 (11),
E637,
E637.
Artículo
78 - Cid-Uribe, J.I., Santibanez-Lopez, C.E., Meneses, E.P., Batista, C.V.F., Jimenez-Vargas, J.M., Ortiz, E., Possani, L.D.. The diversity of venom components of the scorpion species Paravaejovis schwenkmeyeri (Scorpiones: Vaejovidae) revealed by transcriptome and proteome analyses.
Toxicon,
151,
47-62.
Revisión
79 - Ortiz, E., Possani, L.D.. Scorpion toxins to unravel the conundrum of ion channel structure and functioning.
Toxicon,
150,
17-27.
Artículo
Artículo
81 - Garcia-Garcia, F., Corrales-Garcia, L.L., Olamendi-Portugal, T., Restano-Cassulini, R., Vega, R., Vega, M., Ortiz, E., Sandoval-Lopez, G., Soto, E., Corzo, G.. Identification, chemical synthesis and heterologous expression of an antinociceptive peptide from the veined tree frog Trachycephalus typhonius.
Process Biochemistry,
62,
205-214.
Artículo
82 - Hernandez-Vargas, M.J., Gil, J., Lozano, L., Pedraza-Escalona, M., Ortiz, E., Encarnacion-Guevara, S., Alagon, A., Corzo, G.. Proteomic and transcriptomic analysis of saliva components from the hematophagous reduviid Triatoma pallidipennis.
Journal of Proteomics,
162,
30-39.
Artículo
83 - Jimenez-Vargas, J.M., Quintero-Hernandez, V., Gonzalez-Morales, L., Ortiz, E., Possani, L.D.. Design and expression of recombinant toxins from Mexican scorpions of the genus Centruroides for production of antivenoms.
Toxicon,
128,
5-14 [Corrigendum 130 (2017) 126].
Artículo
84 - Romero-Gutierrez, T., Peguero-Sanchez, E., Cevallos, M.A., Batista, C.V.F., Ortiz, E., Possani, L.D.. A Deeper Examination of Thorellius atrox Scorpion Venom Components with Omic Techonologies.
Toxins (Basel),
9 (12),
399.
Artículo
85 - Sanchez-Reyez, A., Batista-Garcia, R.A., Valdes-Garcia, G., Ortiz, E., Perezgasga, L., Zarate-Romero, A., Pastor, N., Folch-Mallol, J.L.. A Family 13 thioesterase isolated from an activated sludge metagenome: Insights into aromatic compounds metabolism.
Proteins,
85 (7),
1222-1237.
Artículo
Artículo
87 - Estrada,G., Silva,A.O., Villegas,E., Ortiz,E., Beirao,P.S.L., Corzo,G.. Heterologous expression of five disulfide-bonded insecticidal spider peptides.
Toxicon,
119,
152-158.
Artículo
88 - Figueroa-Montiel,A., Ramos,M.A., Mares,R.E., Duenas,S., Pimienta,G., Ortiz,E., Possani,L.D., Licea-Navarro,A.F.. In Silico Identification of Protein Disulfide Isomerase Gene Families in the De Novo Assembled Transcriptomes of Four Different Species of the Genus Conus.
PLoS ONE,
11 (2),
e0148390.
Artículo
Revisión
90 - Ortiz,E., Gurrola,G.B., Schwartz,E.F., Possani,L.D.. Scorpion venom components as potential candidates for drug development.
Toxicon,
93,
125-135.
Revisión
91 - Ortiz,E., Possani,L.D.. The unfulfilled promises of scorpion insectotoxins.
Journal of Venomous Animals and Toxins Including Tropical Diseases,
21,
16.
Artículo
92 - Quintero-Hernandez,V., Ramirez-Carreto,S., Romero-Gutierrez,M.T., Valdez-Velazquez,L.L., Becerril,B., Possani,L.D., Ortiz,E.. Transcriptome Analysis of Scorpion Species Belonging to the Vaejovis Genus.
PLoS ONE,
10 (2),
e0117188.
Artículo
93 - Ramirez-Carreto,S., Jimenez-Vargas,J.M., Rivas-Santiago,B., Corzo,G., Possani,L.D., Becerril,B., Ortiz,E.. Peptides from the scorpion Vaejovis punctatus with broad antimicrobial activity.
Peptides,
73,
51-59.
Artículo
94 - Zuniga-Navarrete,F., Gomez,I., Pena,G., Amaro,I., Ortiz,E., Becerril,B., Ibarra,J.E., Bravo,A., Soberon,M.. Identification of Bacillus thuringiensis Cry3Aa toxin domain II loop 1 as the binding site of Tenebrio molitor cadherin repeat CR12.
Insect Biochemistry and Molecular Biology,
59,
50-57.
Internacional
95 - Garcia,F., Villegas,E., Ortiz,E., Corzo,G.. Structural Diversity and Basic/Acidic Residue Balance of Active Cysteine-Rich Insecticidal Peptides from Spiders. Spider Venoms.
Toxinology,
1-20.
Artículo
96 - Campos-Oliver,A., Quiroz-Castaneda,R.E., Ortiz,E., Folch-Mallol,J.L.. Cloning and expression of a hypothetical loosenin from Neurospora crassa.
Revista Latinoamericana de Biotecnologia Ambiental y Algal,
4 (1),
1-7.
Artículo
97 - Ortiz,E., Rendon-Anaya,M., Rego,S.C., Schwartz,E.F., Possani,L.D.. Antarease-like Zn-metalloproteases are ubiquitous in the venom of different scorpion genera.
Biochimica et Biophysica Acta (BBA) - General Subjects,
1840 (6),
1738-1746.
Internacional
98 - Chavez-Haro,A.L., Ortiz,E.. Scorpionism and Dangerous Species of Mexico. Scorpion Venoms.
Toxinology,
201-213.
Internacional
99 - Rendon-Anaya,M., Camargos,T.S., Ortiz,E.. Scorpion Venom Gland Transcriptomics. Scorpion Venoms.
Toxinology,
531-545,
Dordrect: Springer.
Artículo; Actas Paper
100 - Aguilar,M.B., Ortiz,E., Kaas,Q., Lopez-Vera,E., Becerril,B., Possani,L.D., de la Cotera,E.P.. Precursor De13.1 from Conus delessertii defines the novel G gene superfamily.
Peptides,
41,
17-20.
Artículo
101 - Corrales-Garcia,L., Ortiz,E., Castaneda-Delgado,J., Rivas-Santiago,B., Corzo,G.. Bacterial expression and antibiotic activities of recombinant variants of human beta-defensins on pathogenic bacteria and M. tuberculosis.
Protein Expression and Purification,
89 (1),
33-43.
Artículo
102 - Gonzalez-Andrade,M., Becerril-Lujan,B., Sanchez-Lopez,R., Cecena-Alvarez,H., Perez-Carreon,J.I., Ortiz-Suri,E., Fernandez-Velasco,D.A., Del Pozo-Yauner,L.. Mutational and genetic determinants of lambda6 light chain amyloidogenesis.
Febs Journal,
280 (23),
6173-6183.
Artículo
Artículo
104 - Estrada,G., Restano-Cassulini,R., Ortiz,E., Possani,L.D., Corzo,G.. Addition of positive charges at the C-terminal peptide region of CssII; a mammalian scorpion peptide toxin; improves its affinity for sodium channels Nav1.6.
Peptides,
32 (1),
75-79 .
Revisión
105 - Quintero-Hernandez,V., Ortiz,E., Rendon,M.R., Schwartz,E.F., Becerril,B., Corzo,G., Possani,L.D.. Scorpion and spider venom peptides: Gene cloning and peptide expression.
Toxicon,
58 (8),
644-663.
Artículo
106 - Hernandez-Santoyo,A., Del Pozo-Yauner,L., Fuentes-Silva,D., Ortiz,E., Rudino-Pinera,E., Sanchez-Lopez,R., Horjales,E., Becerril,B., Rodriguez-Romero,A.. A single mutation at the sheet switch region results in conformational changes favoring lambda6-light-chain fibrillogenesis.
Journal of Molecular Biology,
396 (2),
280-292.
Internacional
107 - del Pozo-Yauner,L, Ortiz,E., Becerril,B.. Diseases related to protein misfolding. Advances in Protein Physical Chemistry.
469-501,
Kerala: Research Signpost.
Artículo
108 - Del Pozo-Yauner,L., Ortiz,E., Sanchez,R., Sanchez-Lopez,R., Guereca,L., Murphy,C.L., Allen,A., Wall,J.S., Fernandez-Velasco,D.A., Solomon,A., Becerril,B.. Influence of the germline sequence on the thermodynamic stability and fibrillogenicity of human lambda 6 light chains.
Proteins,
72 (2),
684-692.
Artículo
109 - Estrada,G., Garcia,B.I., Schiavon,E., Ortiz,E., Cestele,S., Wanke,E., Possani,L.D., Corzo,G.. Four disulfide-bridged scorpion beta neurotoxin CssII: Heterologous expression and proper folding in vitro.
Biochimica et Biophysica Acta (BBA) - General Subjects,
1770 (8),
1161-1168.
Artículo
110 - Lopez-Vera,E., Aguilar,M.B., Schiavon,E., Marinzi,C., Ortiz,E., Restano-Cassulini,R., Batista,C.V.F., Possani,L.D., Heimer de la Cotera,E.P., Peri,F., Becerril,B., Wanke,E.. Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors.
Febs Journal,
274 (15),
3972-3985.
Artículo
111 - Del Pozo-Yauner,L., Ortiz,E., Becerril,B.. The CDR1 of the human lambdaVI light chains adopts a new canonical structure.
Proteins,
62 (1),
122-129.
Artículo
112 - Aguilar,M.B., Lopez-Vera,E., Ortiz,E., Becerril,B., Possani,L.D., Olivera,B.M., Heimer de la Cotera,E.P.. A Novel Conotoxin from Conus delessertii with Posttranslationally Modified Lysine Residues.
Biochemistry,
44 (33),
11130-11136.
Artículo
113 - Juarez-Gonzalez,V.R., Riano-Umbarila,L., Quintero-Hernandez,V., Olamendi-Portugal,T., Ortiz-Leon,M., Ortiz,E., Possani,L.D., Becerril,B.. Directed Evolution, Phage Display and Combination of Evolved Mutants: A Strategy to Recover the Neutralization Properties of the scFv Version of BCF2 a Neutralizing Monoclonal Antibody Specific to Scorpion Toxin Cn2.
Journal of Molecular Biology,
346 (5),
1287-1297.
Artículo
114 - Manoutcharian,K., Acero,G., Munguia,M.E., Becerril,B., Massieu,L., Govezensky,T., Ortiz,E., Marks,J.D., Cao,C., Ugen,K., Gevorkian,G.. Human single chain Fv antibodies and a complementarity determining region-derived peptide binding to amyloid-beta 1-42.
Neurobiology of Disease,
17 (1),
114-121.
Artículo
115 - Romero,D., Martinez-Salazar,J., Ortiz,E., Rodriguez,C., Valencia-Morales,E.. Repeated sequences in bacterial chromosomes and plasmids: a glimpse from sequenced genomes.
Research in Microbiology,
150 (9-10),
735-743.
*
Artículo
116 - Ortiz,E., Estrada,G., Lizardi,P.M.. PNA molecular beacons for rapid detection of PCR amplicons.
Molecular and cellular probes,
12 (4),
219-226.
117 - Ortiz Suri, Ernesto. Moleculas de PNA en sistemas fluorescentes de deteccion por hibridacion en la discriminacion de alelos .
Instituto de Biotecnologia,
56, [10] paginas,
Doctorado en Biotecnologia,
UNAM.
Artículo
118 - Larin,D.I., Shakhparonov,M.I., Ortiz,E., Kostina,M.B., Modyanov,N.N.. INTRACELLULAR LOCATION OF THE EPITOPES OF 2 NEW MONOCLONAL- ANTIBODIES AGAINST THE VAL(928)-LYS(945) FRAGMENT OF THE ALPHA- SUBUNIT OF NA+,K+-ATPASE - AN APPLICATION TO TOPOLOGICAL MODELS.
Biologicheskie Membrany,
11 (6),
605-613.
*
Artículo
119 - Larin,D.I., Shakhparonov,M.I., Ortiz,E., Kostina,M.B., Modyanov,N.N.. Expression and Purification of Fusion Proteins Containing Na+, K+-Atpase Alpha-Subunit Fragments That Are Located Near the Membrane.
Biologicheskie Membrany,
11 (5),
469-475.
*