Dr. Sabino Pacheco Guillen
Investigador
Microbiología Industrial utilizando proteinas bioinsecticidas
Número de registros: 4
- Activos
- Vencidos
- Análisis genético/funcional de los trasportadores abc como moduladores de toxicidad de las proteínas cry de bacillus thuringiensis en aedes aegypti, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2021 - 2023
- Elucidando el papel funcional de múltiples receptores para las toxinas cry mosquitocidas producidas por bacillus thuringiensis, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2020 - 2022
- Estudio de la arquitectura de poros inducidos por las toxinas cry1a de bacillus thuringiensis en membranas utilizando fluorescencia, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2018 - 2020
- Evolución dirigida de toxinas cry de bacillus thuringiensis como estrategia para rediseñar el reconocimiento toxina-receptor y contender con la resistencia de plagas agrícolas, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2016 - 2018
Total de publicaciones: 40
- Tipo
- Fecha
Artículo in press
1 - Pacheco,S., Gomez,I., Soberon,M., Bravo,A. (2022). A major conformational change of N-terminal helices of Bacillus thuringiensis Cry1Ab insecticidal protein is necessary for membrane insertion and toxicity.
Febs Journal,
Dec 22 [Online first].
Artículo
2 - Lopez-Molina,S., do Nascimento,N.A., Silva-Filha,M.H.N.L., Guerrero,A., Sanchez,J., Pacheco,S., Gill,S.S., Soberon,M., Bravo,A. (2021). In vivo nanoscale analysis of the dynamic synergistic interaction of Bacillus thuringiensis Cry11Aa and Cyt1Aa toxins in Aedes aegypti.
PLoS Pathogens,
17 (1),
e1009199.
Artículo
3 - Lopez-Molina,S., do Nascimento,N.A., Silva-Filha,M.H.N.L., Guerrero,A., Sanchez,J., Pacheco,S., Gill,S.S., Soberon,M., Bravo,A. (2021). In vivo nanoscale analysis of the dynamic synergistic interaction of Bacillus thuringiensis Cry11Aa and Cyt1Aa toxins in Aedes aegypti.
PLoS Pathogens,
17 (1),
e1009199.
Artículo
4 - Pacheco,S., Gomez,I., Chinas,M., Sanchez,J., Soberon,M., Bravo,A. (2021). Whole Genome Sequencing Analysis of Bacillus thuringiensis GR007 Reveals Multiple Pesticidal Protein Genes.
Frontiers in Microbiology,
12,
3268.
Artículo
5 - Sena da Silva,I.H., Gomez,I., Pacheco,S., Sanchez,J., Zhang,J., Luque Castellane,T.C., Aparecida Desiderio J., Soberon,M., Bravo,A., Polanczyk,R.A. (2021). Bacillus thuringiensis Cry1Ab domain III -16 is involved in binding to prohibitin which correlates with toxicity against Helicoverpa armigera (Lepidoptera: Noctuidae).
Applied and Environmental Microbiology,
87 (2),
e01930-20.
Artículo
6 - Chimal-Cazares,F., Hernandez-Martinez,G., Pacheco,S., Ares,M.A., Soria-Bustos,J., Sanchez-Gutierrez,M., Izquierdo-Vega,J.A., Ibarra,J.A., Gonzalez,Y.Merchand JA, Gorvel,J.P., Meresse,S., De la Cruz,M.A. (2020). Molecular Characterization of SehB, a Type II Antitoxin of Salmonella enterica Serotype Typhimurium: Amino Acid Residues Involved in DNA-Binding, Homodimerization, Toxin Interaction, and Virulence.
Frontiers in Microbiology,
11,
614.
Artículo
7 - do Nascimento,N.A., Torres-Quintero,M.C., Lopez-Molina,S., Pacheco,S., Romao,T.P., Pereira-Neves,A., Soberon,M., Bravo,A., Silva-Filha,M.H.N.L. (2020). Functional Bacillus thuringiensis Cyt1Aa is necessary to synergize Lysinibacillus sphaericus Binary toxin against Bin-resistant and refractory mosquito species.
Applied and Environmental Microbiology,
86 (7),
02770-19.
Artículo
8 - do Nascimento,N.A., Torres-Quintero,M.C., Lopez-Molina,S., Pacheco,S., Romao,T.P., Pereira-Neves,A., Soberon,M., Bravo,A., Silva-Filha,M.H.N.L. (2020). Functional Bacillus thuringiensis Cyt1Aa is necessary to synergize Lysinibacillus sphaericus Binary toxin against Bin-resistant and refractory mosquito species.
Applied and Environmental Microbiology,
86 (7),
02770-19.
Artículo
9 - Onofre,J., Pacheco,S., Torres-Quintero,M.C., Gill,S.S., Soberon,M., Bravo,A. (2020). The Cyt1Aa toxin from Bacillus thuringiensis inserts into target membranes via different mechanisms in insects, red blood cells, and lipid liposomes.
Journal of Biological Chemistry,
295 (28),
9606-9617.
Artículo
10 - Pacheco,S., Quiliche,J.P.J., Gomez,I., Sanchez,J., Soberon,M., Bravo,A. (2020). Rearrangement of N-Terminal alpha-Helices of Bacillus thuringiensis Cry1Ab Toxin Essential for Oligomer Assembly and Toxicity.
Toxins (Basel),
12 (10),
E647.
Artículo
11 - Gomez, I., Rodriguez-Chamorro, D.E., Flores-Ramirez, G., Grande, R., Zuniga, F., Portugal, F.J., Sanchez, J., Pacheco, S., Bravo, A., Soberon, M. (2018). Spodoptera frugiperda (J. E. Smith) aminopeptidase N1 is functional receptor of Bacillus thuringiensis Cry1Ca toxin.
Applied and Environmental Microbiology,
84 (17),
UNSP e01089-18
.
Artículo
12 - Pacheco, S., Gomez, I., Sanchez, J., Garcia-Gomez, B.I., Czajkowsky, D.M., Zhang, J., Soberon, M., Bravo, A. (2018). Helix alpha-3 inter-molecular salt bridges and conformational changes are essential for toxicity of Bacillus thuringiensis 3D-Cry toxin family.
Scientific Reports,
8 (1),
10331.
Revisión
13 - Soberon, M., Portugal, L., Garcia-Gomez, B.I., Sanchez, J., Onofre, J., Gomez, I., Pacheco, S., Bravo, A. (2018). Cell lines as models for the study of Cry toxins from Bacillus thuringiensis.
Insect Biochemistry and Molecular Biology,
93,
66-78.
Artículo
14 - Torres-Quintero, M.C., Gomez, I., Pacheco, S., Sanchez, J., Flores, H., Osuna, J., Mendoza, G., Soberon, M., Bravo, A. (2018). Engineering Bacillus thuringiensis Cyt1Aa toxin specificity from dipteran to lepidopteran toxicity.
Scientific Reports,
8 (1),
4989.
Artículo
15 - Wang, Z., Fang, L., Zhou, Z., Pacheco, S., Gomez, I., Song, F., Soberon, M., Zhang, J., Bravo, A. (2018). Specific binding between Bacillus thuringiensis Cry9Aa and Vip3Aa toxins synergizes their toxicity against Asiatic rice borer (Chilo suppressalis).
Journal of Biological Chemistry,
293 (29),
11447-11458.
Artículo
16 - Ares, M.A., Rios-Sarabia, N., De la Cruz, M.A., Rivera-Gutierrez, S., Garcia-Morales, L., Leon-Solis, L., Espitia, C., Pacheco, S., Cerna-Cortes, J.F., Helguera-Repetto, C.A., Garcia, M.J., Gonzalez Y, Merchand J.A. (2017). The sigma factor SigD of Mycobacterium tuberculosis putatively enhances gene expression of the septum site determining protein under stressful environments.
New Microbiologica,
40 (3).
Artículo
17 - Ares, M.A., Fernandez-Vazquez, J.L., Pacheco, S., Martinez-Santos, V.I., Jarillo-Quijada, M.D., Torres, J., Alcantar-Curiel, M.D., Gonzalez Y Merchand J.A., De la Cruz, M.A. (2017). Additional regulatory activities of MrkH for the transcriptional expression of the Klebsiella pneumoniae mrk genes: Antagonist of H-NS and repressor.
PLoS ONE,
12 (3),
e0173285.
Artículo
18 - De la Cruz, M.A., Ruiz-Tagle, A., Ares, M.A., Pacheco, S., Yanez, J.A., Cedillo, L., Torres, J., Giron, J.A. (2017). The Expression of Longus type 4 pilus of enterotoxigenic Escherichia coli is regulated by LngR and LngS, and by H-NS, CpxR, and CRP global regulators.
Environmental Microbiology,
19 (5),
1761-1775.
Artículo; Actas Paper
19 - Onofre, J., Gaytan, M.O., Pena-Cardena, A., Garcia-Gomez, B.I., Pacheco, S., Gomez, I., Bravo, A., Soberon, M. (2017). Identification of Aminopeptidase-N2 as a Cry2Ab binding protein in Manduca sexta.
Peptides,
98,
93-98.
Artículo
20 - Pacheco, S., Gomez, I., Sanchez, J., Garcia-Gomez, B.I., Soberon, M., Bravo, A. (2017). Intra-molecular salt bridge in Bacillus thuringiensis Cry4Ba toxin is involved in the stability of helix alpha-3 that is needed for oligomerization and insecticidal activity.
Applied and Environmental Microbiology,
83 (20),
e01515-e01517.
Artículo
21 - Xiao, Y., Dai, Q., Hu, R., Pacheco, S., Yang, Y., Liang, G., Soberon, M., Bravo, A., Liu, K., Wu, K. (2017). A Single Point Mutation Resulting in Cadherin Mis-localization Underpins Resistance against Bacillus thuringiensis Toxin in Cotton Bollworm.
Journal of Biological Chemistry,
292 (7),
2933-2943.
Artículo
22 - Cardenas-Mondragon,M.G., Ares,M.A., Panunzi,L.G., Pacheco,S., Camorlinga-Ponce,M., Giron,J.A., Torres,J., De la Cruz,M.A. (2016). Transcriptional Profiling of Type II Toxin-Antitoxin Genes of Helicobacter pylori under Different Environmental Conditions: Identification of HP0967-HP0968 System.
Frontiers in Microbiology,
7,
1872.
Artículo
23 - Pacheco,S., Canton,E., Zuniga-Navarrete,F., Pecorari,F., Bravo,A., Soberon,M. (2015). Improvement and efficient display of Bacillus thuringiensis toxins on M13 phages and ribosomes.
AMB Express,
5 (1),
73.
Artículo
24 - Behar,G., Pacheco,S., Maillasson,M., Mouratou,B., Pecorari,F. (2014). Switching an anti-IgG binding site between archaeal extremophilic proteins results in Affitins with enhanced pH stability.
Journal of Biotechnology,
192 (Part A),
123-129.
*
Artículo
25 - Correa,A., Pacheco,S., Mechaly,A.E., Obal,G., Behar,G., Mouratou,B., Oppezzo,P., Alzari,P.M., Pecorari,F. (2014). Potent and specific inhibition of glycosidases by small artificial binding proteins (affitins).
PLoS ONE,
9 (5),
e97438.
*
Artículo
26 - Pacheco,S., Behar,G., Maillasson,M., Mouratou,B., Pecorari,F. (2014). Affinity transfer to the archaeal extremophilic Sac7d protein by insertion of a CDR.
Protein Engineering Design & Selection,
27 (10),
431-438.
*
Artículo
27 - Ares,M.A., Alcantar-Curiel,M.D., Jimenez-Galicia,C., Rios-Sarabia,N., Pacheco,S., De la Cruz,M.A. (2013). Antibiotic resistance of gram-negative bacilli isolated from pediatric patients with nosocomial bloodstream infections in a Mexican tertiary care hospital.
Chemotherapy,
59 (5),
361-368.
Artículo
28 - Cancino-Rodezno,A., Alexander,C., Villasenor,R., Pacheco,S., Porta,H., Pauchet,Y., Soberon,M., Gill,S.S., Bravo,A. (2010). The mitogen-activated protein kinase p38 is involved in insect defense against cry toxins from Bacillus thuringiensis.
Insect Biochemistry and Molecular Biology,
40 (1),
58-63 [corrigendum 43 (9) 898 2013 ].
Artículo
29 - Gomez,I., Arenas,I., Pacheco,S., Bravo,A., Soberon,M. (2010). New Insights into the Mode of Action of Cry1Ab Toxin Used in Transgenic Insect-resistant Crops.
Southwestern Entomologist,
35 (3),
387-390.
Artículo
30 - Pacheco,S., Gomez,I., Gill,S.S., Bravo,A., Soberon,M. (2009). Enhancement of insecticidal activity of Bacillus thuringiensis Cry1A toxins by fragments of a toxin-binding cadherin correlates with oligomer formation.
Peptides,
30 (3),
583-588.
Artículo
31 - Pacheco,S., Gomez,I., Arenas,I., Saab-Rincon,G., Rodriguez-Almazan,C., Gill,S.S., Bravo,A., Soberon,M. (2009). Domain II loop 3 of Bacillus thuringiensis Cry1Ab toxin is involved in a "ping-pong" binding mechanism with Manduca sexta aminopetidase-N and cadherin receptors.
Journal of Biological Chemistry,
284 (47),
32750-32757.
Artículo
32 - Rodriguez-Almazan,C., Zavala,L.E., Munoz-Garay,C., Jimenez-Juarez,N., Pacheco,S., Masson,L., Soberon,M., Bravo,A. (2009). Dominant negative mutants of Bacillus thuringiensis Cry1Ab toxin function as anti-toxins: demonstration of the role of oligomerization in toxicity.
PLoS ONE,
4 (5),
e5545 [Erratum 2013 8 (2)].
Artículo; Actas Paper
33 - Fernandez,L.E., Gomez,I., Pacheco,S., Arenas,I., Gill,S.S., Bravo,A., Soberon,M. (2008). Employing phage display to study the mode of action of Bacillus thuringiensis Cry toxins.
Peptides,
29 (2),
324-329.
Artículo
34 - Pacheco,S., Gomez,I., Sato,R., Bravo,A., Soberon,M. (2006). Functional display of Bacillus thuringiensis Cry1Ac toxin on T7 phage.
Journal of Invertebrate Pathology,
92 (1),
45-49.
35 - Bravo, A., Pacheco, S., Gomez, I., Garcia-Gomez, B., Onofre, J., Soberon, M. (2017). Insecticidal Proteins from Bacillus thuringiensis and Their Mechanism of Action. Bacillus thuringiensis and Lysinibacillus sphaericus: Characterization and use in the field of biocontrol.
53-66,
Cham: Springer.
*
Internacional
36 - Bravo, A., Martinez-de-Castro, D. L., Sanchez-Quintana, J., Canton, P. E., Mendoza, G., Gomez, I., Pacheco, S., Garcia-Gomez, B. I., Onofre, J., Ocelotl, J., Soberon, M. (2015). Mechanism of action of Bacillus thuringiensis insecticidal toxins and their use in the control of insect pests. Comprehensive Sourcebook of Bacterial Protein Toxins.
858-873,
4a ed.
Internacional
37 - Soberon,M., Garcia-Gomez,B.I., Pacheco,S., Sanchez-Quintana,J., Tabashnik,B.E., Bravo,A. (2015). Countering pest resistance with genetically modified Bt toxins. Bt resistance-characterization and strategies for GM crops expressing Bacillus thuringiensis .
CABI Biotechnology Series Volume: 4,
150-161,
Oxford.
Internacional
38 - Pacheco,S., Soberon,M. (2012). Phage display: Fundamentals and applications. Tools to Understand Protein-Protein Interactions.
143,
Kerala: Research Signpost.
nacional divulgacion
39 - Gomez,I., Pacheco,S. (2022). La bacteria Bacillus thuringiensis como bioinsecticida en la agricultura actual.
Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM,
29.
40 - Pacheco Guillen, Sabino (2010). Papel del asa 3 del dominio II de las toxinas Cry1A's de Bacillus thuringiensis en el mecanismo de toxicidad : un blanco potencial para modificar el reconocimiento de sus receptores.
Instituto de Biotecnologia,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Soberon Chavez, Mario
Artículo in press
41 - Pacheco,S., Gomez,I., Soberon,M., Bravo,A.. A major conformational change of N-terminal helices of Bacillus thuringiensis Cry1Ab insecticidal protein is necessary for membrane insertion and toxicity.
Febs Journal,
Dec 22 [Online first].
nacional divulgacion
42 - Gomez,I., Pacheco,S.. La bacteria Bacillus thuringiensis como bioinsecticida en la agricultura actual.
Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM,
29.
Artículo
43 - Lopez-Molina,S., do Nascimento,N.A., Silva-Filha,M.H.N.L., Guerrero,A., Sanchez,J., Pacheco,S., Gill,S.S., Soberon,M., Bravo,A.. In vivo nanoscale analysis of the dynamic synergistic interaction of Bacillus thuringiensis Cry11Aa and Cyt1Aa toxins in Aedes aegypti.
PLoS Pathogens,
17 (1),
e1009199.
Artículo
44 - Lopez-Molina,S., do Nascimento,N.A., Silva-Filha,M.H.N.L., Guerrero,A., Sanchez,J., Pacheco,S., Gill,S.S., Soberon,M., Bravo,A.. In vivo nanoscale analysis of the dynamic synergistic interaction of Bacillus thuringiensis Cry11Aa and Cyt1Aa toxins in Aedes aegypti.
PLoS Pathogens,
17 (1),
e1009199.
Artículo
45 - Pacheco,S., Gomez,I., Chinas,M., Sanchez,J., Soberon,M., Bravo,A.. Whole Genome Sequencing Analysis of Bacillus thuringiensis GR007 Reveals Multiple Pesticidal Protein Genes.
Frontiers in Microbiology,
12,
3268.
Artículo
46 - Sena da Silva,I.H., Gomez,I., Pacheco,S., Sanchez,J., Zhang,J., Luque Castellane,T.C., Aparecida Desiderio J., Soberon,M., Bravo,A., Polanczyk,R.A.. Bacillus thuringiensis Cry1Ab domain III -16 is involved in binding to prohibitin which correlates with toxicity against Helicoverpa armigera (Lepidoptera: Noctuidae).
Applied and Environmental Microbiology,
87 (2),
e01930-20.
Artículo
47 - Chimal-Cazares,F., Hernandez-Martinez,G., Pacheco,S., Ares,M.A., Soria-Bustos,J., Sanchez-Gutierrez,M., Izquierdo-Vega,J.A., Ibarra,J.A., Gonzalez,Y.Merchand JA, Gorvel,J.P., Meresse,S., De la Cruz,M.A.. Molecular Characterization of SehB, a Type II Antitoxin of Salmonella enterica Serotype Typhimurium: Amino Acid Residues Involved in DNA-Binding, Homodimerization, Toxin Interaction, and Virulence.
Frontiers in Microbiology,
11,
614.
Artículo
48 - do Nascimento,N.A., Torres-Quintero,M.C., Lopez-Molina,S., Pacheco,S., Romao,T.P., Pereira-Neves,A., Soberon,M., Bravo,A., Silva-Filha,M.H.N.L.. Functional Bacillus thuringiensis Cyt1Aa is necessary to synergize Lysinibacillus sphaericus Binary toxin against Bin-resistant and refractory mosquito species.
Applied and Environmental Microbiology,
86 (7),
02770-19.
Artículo
49 - do Nascimento,N.A., Torres-Quintero,M.C., Lopez-Molina,S., Pacheco,S., Romao,T.P., Pereira-Neves,A., Soberon,M., Bravo,A., Silva-Filha,M.H.N.L.. Functional Bacillus thuringiensis Cyt1Aa is necessary to synergize Lysinibacillus sphaericus Binary toxin against Bin-resistant and refractory mosquito species.
Applied and Environmental Microbiology,
86 (7),
02770-19.
Artículo
50 - Onofre,J., Pacheco,S., Torres-Quintero,M.C., Gill,S.S., Soberon,M., Bravo,A.. The Cyt1Aa toxin from Bacillus thuringiensis inserts into target membranes via different mechanisms in insects, red blood cells, and lipid liposomes.
Journal of Biological Chemistry,
295 (28),
9606-9617.
Artículo
51 - Pacheco,S., Quiliche,J.P.J., Gomez,I., Sanchez,J., Soberon,M., Bravo,A.. Rearrangement of N-Terminal alpha-Helices of Bacillus thuringiensis Cry1Ab Toxin Essential for Oligomer Assembly and Toxicity.
Toxins (Basel),
12 (10),
E647.
Artículo
52 - Gomez, I., Rodriguez-Chamorro, D.E., Flores-Ramirez, G., Grande, R., Zuniga, F., Portugal, F.J., Sanchez, J., Pacheco, S., Bravo, A., Soberon, M.. Spodoptera frugiperda (J. E. Smith) aminopeptidase N1 is functional receptor of Bacillus thuringiensis Cry1Ca toxin.
Applied and Environmental Microbiology,
84 (17),
UNSP e01089-18
.
Artículo
53 - Pacheco, S., Gomez, I., Sanchez, J., Garcia-Gomez, B.I., Czajkowsky, D.M., Zhang, J., Soberon, M., Bravo, A.. Helix alpha-3 inter-molecular salt bridges and conformational changes are essential for toxicity of Bacillus thuringiensis 3D-Cry toxin family.
Scientific Reports,
8 (1),
10331.
Revisión
54 - Soberon, M., Portugal, L., Garcia-Gomez, B.I., Sanchez, J., Onofre, J., Gomez, I., Pacheco, S., Bravo, A.. Cell lines as models for the study of Cry toxins from Bacillus thuringiensis.
Insect Biochemistry and Molecular Biology,
93,
66-78.
Artículo
55 - Torres-Quintero, M.C., Gomez, I., Pacheco, S., Sanchez, J., Flores, H., Osuna, J., Mendoza, G., Soberon, M., Bravo, A.. Engineering Bacillus thuringiensis Cyt1Aa toxin specificity from dipteran to lepidopteran toxicity.
Scientific Reports,
8 (1),
4989.
Artículo
56 - Wang, Z., Fang, L., Zhou, Z., Pacheco, S., Gomez, I., Song, F., Soberon, M., Zhang, J., Bravo, A.. Specific binding between Bacillus thuringiensis Cry9Aa and Vip3Aa toxins synergizes their toxicity against Asiatic rice borer (Chilo suppressalis).
Journal of Biological Chemistry,
293 (29),
11447-11458.
Artículo
57 - Ares, M.A., Rios-Sarabia, N., De la Cruz, M.A., Rivera-Gutierrez, S., Garcia-Morales, L., Leon-Solis, L., Espitia, C., Pacheco, S., Cerna-Cortes, J.F., Helguera-Repetto, C.A., Garcia, M.J., Gonzalez Y, Merchand J.A.. The sigma factor SigD of Mycobacterium tuberculosis putatively enhances gene expression of the septum site determining protein under stressful environments.
New Microbiologica,
40 (3).
Artículo
58 - Ares, M.A., Fernandez-Vazquez, J.L., Pacheco, S., Martinez-Santos, V.I., Jarillo-Quijada, M.D., Torres, J., Alcantar-Curiel, M.D., Gonzalez Y Merchand J.A., De la Cruz, M.A.. Additional regulatory activities of MrkH for the transcriptional expression of the Klebsiella pneumoniae mrk genes: Antagonist of H-NS and repressor.
PLoS ONE,
12 (3),
e0173285.
Artículo
59 - De la Cruz, M.A., Ruiz-Tagle, A., Ares, M.A., Pacheco, S., Yanez, J.A., Cedillo, L., Torres, J., Giron, J.A.. The Expression of Longus type 4 pilus of enterotoxigenic Escherichia coli is regulated by LngR and LngS, and by H-NS, CpxR, and CRP global regulators.
Environmental Microbiology,
19 (5),
1761-1775.
Artículo; Actas Paper
60 - Onofre, J., Gaytan, M.O., Pena-Cardena, A., Garcia-Gomez, B.I., Pacheco, S., Gomez, I., Bravo, A., Soberon, M.. Identification of Aminopeptidase-N2 as a Cry2Ab binding protein in Manduca sexta.
Peptides,
98,
93-98.
Artículo
61 - Pacheco, S., Gomez, I., Sanchez, J., Garcia-Gomez, B.I., Soberon, M., Bravo, A.. Intra-molecular salt bridge in Bacillus thuringiensis Cry4Ba toxin is involved in the stability of helix alpha-3 that is needed for oligomerization and insecticidal activity.
Applied and Environmental Microbiology,
83 (20),
e01515-e01517.
Artículo
62 - Xiao, Y., Dai, Q., Hu, R., Pacheco, S., Yang, Y., Liang, G., Soberon, M., Bravo, A., Liu, K., Wu, K.. A Single Point Mutation Resulting in Cadherin Mis-localization Underpins Resistance against Bacillus thuringiensis Toxin in Cotton Bollworm.
Journal of Biological Chemistry,
292 (7),
2933-2943.
63 - Bravo, A., Pacheco, S., Gomez, I., Garcia-Gomez, B., Onofre, J., Soberon, M.. Insecticidal Proteins from Bacillus thuringiensis and Their Mechanism of Action. Bacillus thuringiensis and Lysinibacillus sphaericus: Characterization and use in the field of biocontrol.
53-66,
Cham: Springer.
*
Artículo
64 - Cardenas-Mondragon,M.G., Ares,M.A., Panunzi,L.G., Pacheco,S., Camorlinga-Ponce,M., Giron,J.A., Torres,J., De la Cruz,M.A.. Transcriptional Profiling of Type II Toxin-Antitoxin Genes of Helicobacter pylori under Different Environmental Conditions: Identification of HP0967-HP0968 System.
Frontiers in Microbiology,
7,
1872.
Artículo
65 - Pacheco,S., Canton,E., Zuniga-Navarrete,F., Pecorari,F., Bravo,A., Soberon,M.. Improvement and efficient display of Bacillus thuringiensis toxins on M13 phages and ribosomes.
AMB Express,
5 (1),
73.
Internacional
66 - Bravo, A., Martinez-de-Castro, D. L., Sanchez-Quintana, J., Canton, P. E., Mendoza, G., Gomez, I., Pacheco, S., Garcia-Gomez, B. I., Onofre, J., Ocelotl, J., Soberon, M.. Mechanism of action of Bacillus thuringiensis insecticidal toxins and their use in the control of insect pests. Comprehensive Sourcebook of Bacterial Protein Toxins.
858-873,
4a ed.
Internacional
67 - Soberon,M., Garcia-Gomez,B.I., Pacheco,S., Sanchez-Quintana,J., Tabashnik,B.E., Bravo,A.. Countering pest resistance with genetically modified Bt toxins. Bt resistance-characterization and strategies for GM crops expressing Bacillus thuringiensis .
CABI Biotechnology Series Volume: 4,
150-161,
Oxford.
Artículo
68 - Behar,G., Pacheco,S., Maillasson,M., Mouratou,B., Pecorari,F.. Switching an anti-IgG binding site between archaeal extremophilic proteins results in Affitins with enhanced pH stability.
Journal of Biotechnology,
192 (Part A),
123-129.
*
Artículo
69 - Correa,A., Pacheco,S., Mechaly,A.E., Obal,G., Behar,G., Mouratou,B., Oppezzo,P., Alzari,P.M., Pecorari,F.. Potent and specific inhibition of glycosidases by small artificial binding proteins (affitins).
PLoS ONE,
9 (5),
e97438.
*
Artículo
70 - Pacheco,S., Behar,G., Maillasson,M., Mouratou,B., Pecorari,F.. Affinity transfer to the archaeal extremophilic Sac7d protein by insertion of a CDR.
Protein Engineering Design & Selection,
27 (10),
431-438.
*
Artículo
71 - Ares,M.A., Alcantar-Curiel,M.D., Jimenez-Galicia,C., Rios-Sarabia,N., Pacheco,S., De la Cruz,M.A.. Antibiotic resistance of gram-negative bacilli isolated from pediatric patients with nosocomial bloodstream infections in a Mexican tertiary care hospital.
Chemotherapy,
59 (5),
361-368.
Internacional
72 - Pacheco,S., Soberon,M.. Phage display: Fundamentals and applications. Tools to Understand Protein-Protein Interactions.
143,
Kerala: Research Signpost.
Artículo
73 - Cancino-Rodezno,A., Alexander,C., Villasenor,R., Pacheco,S., Porta,H., Pauchet,Y., Soberon,M., Gill,S.S., Bravo,A.. The mitogen-activated protein kinase p38 is involved in insect defense against cry toxins from Bacillus thuringiensis.
Insect Biochemistry and Molecular Biology,
40 (1),
58-63 [corrigendum 43 (9) 898 2013 ].
Artículo
74 - Gomez,I., Arenas,I., Pacheco,S., Bravo,A., Soberon,M.. New Insights into the Mode of Action of Cry1Ab Toxin Used in Transgenic Insect-resistant Crops.
Southwestern Entomologist,
35 (3),
387-390.
75 - Pacheco Guillen, Sabino. Papel del asa 3 del dominio II de las toxinas Cry1A's de Bacillus thuringiensis en el mecanismo de toxicidad : un blanco potencial para modificar el reconocimiento de sus receptores.
Instituto de Biotecnologia,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Soberon Chavez, Mario
Artículo
76 - Pacheco,S., Gomez,I., Gill,S.S., Bravo,A., Soberon,M.. Enhancement of insecticidal activity of Bacillus thuringiensis Cry1A toxins by fragments of a toxin-binding cadherin correlates with oligomer formation.
Peptides,
30 (3),
583-588.
Artículo
77 - Pacheco,S., Gomez,I., Arenas,I., Saab-Rincon,G., Rodriguez-Almazan,C., Gill,S.S., Bravo,A., Soberon,M.. Domain II loop 3 of Bacillus thuringiensis Cry1Ab toxin is involved in a "ping-pong" binding mechanism with Manduca sexta aminopetidase-N and cadherin receptors.
Journal of Biological Chemistry,
284 (47),
32750-32757.
Artículo
78 - Rodriguez-Almazan,C., Zavala,L.E., Munoz-Garay,C., Jimenez-Juarez,N., Pacheco,S., Masson,L., Soberon,M., Bravo,A.. Dominant negative mutants of Bacillus thuringiensis Cry1Ab toxin function as anti-toxins: demonstration of the role of oligomerization in toxicity.
PLoS ONE,
4 (5),
e5545 [Erratum 2013 8 (2)].
Artículo; Actas Paper
79 - Fernandez,L.E., Gomez,I., Pacheco,S., Arenas,I., Gill,S.S., Bravo,A., Soberon,M.. Employing phage display to study the mode of action of Bacillus thuringiensis Cry toxins.
Peptides,
29 (2),
324-329.
Artículo
80 - Pacheco,S., Gomez,I., Sato,R., Bravo,A., Soberon,M.. Functional display of Bacillus thuringiensis Cry1Ac toxin on T7 phage.
Journal of Invertebrate Pathology,
92 (1),
45-49.