Dr. Luis Caspeta Guadarrama
Investigador
Número de registros: 2
- Activos
- Vencidos
- Evaluación de los nichos termo-ácidos de cepas de saccharomyces cerevisiae y de la importancia de estos en la producción de etanol y ácidos orgánicos, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2022 - 2023
- Manipulación del estado redox intracelular de saccharomyces cerevisiae para la producción de ácido succínico y etanol, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2019 - 2020
Doctorado, en Ciencias, Instituto de Biotecnología-UNAM
Maestría, Biotecnología, Centro de Investigación en Biotecnología-UAEM
Licenciatura, Ingeniería Química, Facultad de Ciencias Químicas e Ingeniería-UAEM
- Activos
- Graduados
1 - Arenas Cedillo, Leon Fernando (2021). Produccion de esteres de esteroles en S. cerevisiae /.
Instituto de Biotecnología,
Maestría en Ciencias Bioquímicas,
UNAM.
Asesor: Caspeta, Luis
2 - Balderas Ramirez, Emiliano (2021). Conversión de xilosa a etanol en levaduras termo-tolerantes.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Caspeta, Luis
Total de publicaciones: 28
- Tipo
- Fecha
artículo
3 - Salas-Navarrete,P.C., Montees de Oca Miranda,A.I., Martinez,A., Caspeta,L. (2022). Evolutionary and reverse engineering to increase Saccharomyces cerevisiae tolerance to acetic acid, acidic pH, and high temperature.
Applied Microbiology and Biotechnology,
106 (1),
383-399.
Artículo
Artículo
5 - Caspeta,L., Kerkhoven,E.J., Martinez,A., Nielsen,J. (2021). The yeastGemMap: A process diagram to assist yeast systems-metabolic studies.
Biotechnology and Bioengineering,
118 (12),
4800-4814.
Artículo
6 - Caspeta, L., Coronel, J., de Oca, A. M., Abarca, E., Gonzalez, L., Martinez, A. (2019). Engineering high-gravity fermentations for ethanol production at elevated-temperature with Saccharomyces cerevisiae.
Biotechnology and Bioengineering,
116 (10),
2587-2597.
Artículo
7 - Bertrand,B., Trejo-Hernandez,M.R., Morales-Guzman,D., Caspeta,L., Suarez-Rodriguez R., Martinez-Morales,F. (2016). Functional expression, production, and biochemical characterization of a laccase using yeast surface display technology.
Fungal Biology,
120 (12),
1609-1622.
*
Artículo
8 - Caspeta,L., Chen,Y., Nielsen,J. (2016). Thermotolerant yeasts selected by adaptive evolution express heat stress response at 30 degrees C.
Scientific Reports,
6,
27003.
*
Revisión
9 - Caspeta,L., Castillo,T., Nielsen,J. (2015). Modifying Yeast Tolerance to Inhibitory Conditions of Ethanol Production Processes.
Frontiers in Bioengineering and Biotechnology,
3,
184.
*
Artículo
10 - Caspeta,L., Nielsen,J. (2015). Thermotolerant Yeast Strains Adapted by Laboratory Evolution Show Trade-Off at Ancestral Temperatures and Preadaptation to Other Stresses.
MBio,
6 (4),
e00431.
*
Artículo
11 - Caspeta,L., Caro-Bermudez,M.A., Ponce-Noyola,T., Martinez,A. (2014). Enzymatic hydrolysis at high-solids loadings for the conversion of agave bagasse to fuel ethanol.
Applied Energy,
113,
277-286.
Artículo
12 - Caspeta,L., Chen,Y., Ghiaci,P., Feizi,A., Buskov,S., Hallstrom,B.M., Petranovic,D., Nielsen,J. (2014). Biofuels. Altered sterol composition renders yeast thermotolerant.
Science,
346 (6205),
75-78.
*
Revisión
13 - Caspeta,L., Nielsen,J. (2013). Toward systems metabolic engineering of Aspergillus and Pichia species for the production of chemicals and biofuels.
Biotechnology Journal,
8 (5),
534-544.
*
Carta
14 - Caspeta,L., Nielsen,J. (2013). Economic and environmental impacts of microbial biodiesel.
Nature Biotechnology,
31 (9),
789-793.
*
Artículo
15 - Caspeta,L., Lara,A.R., Perez,N.O., FLORES,N., Bolivar,F., Ramirez,O.T. (2013). Enhancing thermo-induced recombinant protein production in Escherichia coli by temperature oscillations and post-induction nutrient feeding strategies.
Journal of Biotechnology,
167 (1),
47-55.
Artículo
16 - Caspeta,L., Shoaie,S., Agren,R., Nookaew,I., Nielsen,J. (2012). Genome-scale metabolic reconstructions of Pichia stipitis and Pichia pastoris and in silico evaluation of their potentials.
BMC Systems Biology,
6,
24.
*
Artículo
17 - Lara,A.R., Knabben,I., Regestein,L., Sassi,J., Caspeta,L., Ramirez,O.T., Buchs,J. (2011). Comparison of oxygen enriched air vs. pressure cultivations to increase oxygen transfer and to scale-up plasmid DNA production fermentations.
Engineering in Life Sciences,
11 (4),
382-386.
Artículo
18 - Soto,R., Caspeta,L., Barron,B., Gosset,G., Ramirez,O.T., Lara,A.R. (2011). High cell-density cultivation in batch mode for plasmid DNA production by a metabolically engineered E. coli strain with minimized overflow metabolism.
Biochemical Engineering Journal,
56 (3),
165-171.
Revisión
19 - Valdez-Cruz,N.A., Caspeta,L., Perez,N.O., Ramirez,O.T., Trujillo-Roldan,M.A. (2010). Production of recombinant proteins in E. coli by the heat inducible expression system based on the phage lambda pL and/or pR promoters.
Microbial Cell Factories,
9 (1),
18.
Artículo
20 - Caspeta,L., FLORES,N., Perez,N.O., Bolivar,F., Ramirez,O.T. (2009). The effect of heating rate on Escherichia coli metabolism, physiological stress, transcriptional response, and production of temperature-induced recombinant protein: a scale-down study.
Biotechnology and Bioengineering,
102 (2),
468-482.
Artículo
21 - Lara,A.R., Caspeta,L., Gosset,G., Bolivar,F., Ramirez,O.T. (2008). Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: An alternative to fed-batch cultures.
Biotechnology and Bioengineering,
99 (4),
893-901.
Artículo
22 - Villarreal,M.L., Caspeta,L., Quintero-Ramirez,R. (2008). From the Mayan Highlands to the Bioreactors: In Vitro Tissue Culture of the Mexican Medicinal Plant Solanum chrysotrichum.
Electronic Journal of Integrative Biosciences,
3 (1),
20-28.
*
Artículo
23 - Caspeta,L., Quintero,R., Villarreal,M.L. (2005). Novel airlift reactor fitting for hairy root cultures: developmental and performance studies.
Biotechnology Progress,
21 (3),
735-740.
*
Artículo
24 - Caspeta,L., Nieto,I., Zamilpa,A., Alvarez,L., Quintero,R., Villarreal,M.L. (2005). Solanum chrysotrichum hairy root cultures: characterization, scale-up and production of five antifungal saponins for human use.
Planta Medica,
71 (11),
1084-1087.
*
Internacional
25 - Caspeta,L., Salas-Navarrete,P.C. (2019). Reduction of the Saccharomyces cerevisiae Genome: Challenges and Perspectives. Minimal Cells: Design, Construction, Biotechnological Applications.
117-139,
Cham: Springer International Publishing.
Internacional
26 - Caspeta, L., Castillo, T. (2017). Systems Metabolic Engineering of Saccharomyces cerevisiae for Production of Biochemicals from Biomass. Engineering of Microorganisms for the Production of Chemicals and Biofuels from Renewable Resources.
31-65,
Cham.
*
Editorial material
27 - Fletcher,E., Chen,Y., Caspeta,L., Feizi,A. (2022). Editorial: Genomic strategies for efficient microbial cell factories.
Frontiers in Bioengineering and Biotechnology,
10,
962828.
nacional divulgación
28 - Balderas,E., Caspeta,L. (2021). Cadenas de valor: de la refinería actual a las biorrefinerías.
Biotecnologia en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM,
27,
31-35.
Editorial Material
29 - Caspeta,L., Buijs,N.A.A., Nielsen,J. (2013). The role of biofuels in the future energy supply.
Energy & Environmental Science,
6 (4),
1077-1082.
*
30 - Caspeta Guadarrama, Luis (2009). Escalamiento descendente del proceso de produccion de proteina heterologa por termoinduccion de cultivos de alta densidad celular de Escherichia coli : estudio de la respuesta transcripcional al choque termico .
Instituto de Biotecnologia,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Ramirez, Octavio T.
artículo
31 - Salas-Navarrete,P.C., Montees de Oca Miranda,A.I., Martinez,A., Caspeta,L.. Evolutionary and reverse engineering to increase Saccharomyces cerevisiae tolerance to acetic acid, acidic pH, and high temperature.
Applied Microbiology and Biotechnology,
106 (1),
383-399.
Artículo
32 - Vera-Lopez-Portillo,F., Sierra-Ibarra,E., Vera-Estrella,R., Revah,S., Ramirez,O.T., Caspeta,L., Martinez,A.. Growth and phycocyanin production with Galdieria sulphuraria UTEX 2919 using xylose, glucose, and corn stover hydrolysates under heterotrophy and mixotrophy.
Algal Research,
65.
Editorial material
33 - Fletcher,E., Chen,Y., Caspeta,L., Feizi,A.. Editorial: Genomic strategies for efficient microbial cell factories.
Frontiers in Bioengineering and Biotechnology,
10,
962828.
Artículo
34 - Caspeta,L., Kerkhoven,E.J., Martinez,A., Nielsen,J.. The yeastGemMap: A process diagram to assist yeast systems-metabolic studies.
Biotechnology and Bioengineering,
118 (12),
4800-4814.
nacional divulgación
35 - Balderas,E., Caspeta,L.. Cadenas de valor: de la refinería actual a las biorrefinerías.
Biotecnologia en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM,
27,
31-35.
Artículo
36 - Caspeta, L., Coronel, J., de Oca, A. M., Abarca, E., Gonzalez, L., Martinez, A.. Engineering high-gravity fermentations for ethanol production at elevated-temperature with Saccharomyces cerevisiae.
Biotechnology and Bioengineering,
116 (10),
2587-2597.
Internacional
37 - Caspeta,L., Salas-Navarrete,P.C.. Reduction of the Saccharomyces cerevisiae Genome: Challenges and Perspectives. Minimal Cells: Design, Construction, Biotechnological Applications.
117-139,
Cham: Springer International Publishing.
Internacional
38 - Caspeta, L., Castillo, T.. Systems Metabolic Engineering of Saccharomyces cerevisiae for Production of Biochemicals from Biomass. Engineering of Microorganisms for the Production of Chemicals and Biofuels from Renewable Resources.
31-65,
Cham.
*
Artículo
39 - Bertrand,B., Trejo-Hernandez,M.R., Morales-Guzman,D., Caspeta,L., Suarez-Rodriguez R., Martinez-Morales,F.. Functional expression, production, and biochemical characterization of a laccase using yeast surface display technology.
Fungal Biology,
120 (12),
1609-1622.
*
Artículo
40 - Caspeta,L., Chen,Y., Nielsen,J.. Thermotolerant yeasts selected by adaptive evolution express heat stress response at 30 degrees C.
Scientific Reports,
6,
27003.
*
Revisión
41 - Caspeta,L., Castillo,T., Nielsen,J.. Modifying Yeast Tolerance to Inhibitory Conditions of Ethanol Production Processes.
Frontiers in Bioengineering and Biotechnology,
3,
184.
*
Artículo
42 - Caspeta,L., Nielsen,J.. Thermotolerant Yeast Strains Adapted by Laboratory Evolution Show Trade-Off at Ancestral Temperatures and Preadaptation to Other Stresses.
MBio,
6 (4),
e00431.
*
Artículo
43 - Caspeta,L., Caro-Bermudez,M.A., Ponce-Noyola,T., Martinez,A.. Enzymatic hydrolysis at high-solids loadings for the conversion of agave bagasse to fuel ethanol.
Applied Energy,
113,
277-286.
Artículo
44 - Caspeta,L., Chen,Y., Ghiaci,P., Feizi,A., Buskov,S., Hallstrom,B.M., Petranovic,D., Nielsen,J.. Biofuels. Altered sterol composition renders yeast thermotolerant.
Science,
346 (6205),
75-78.
*
Revisión
45 - Caspeta,L., Nielsen,J.. Toward systems metabolic engineering of Aspergillus and Pichia species for the production of chemicals and biofuels.
Biotechnology Journal,
8 (5),
534-544.
*
Carta
46 - Caspeta,L., Nielsen,J.. Economic and environmental impacts of microbial biodiesel.
Nature Biotechnology,
31 (9),
789-793.
*
Artículo
47 - Caspeta,L., Lara,A.R., Perez,N.O., FLORES,N., Bolivar,F., Ramirez,O.T.. Enhancing thermo-induced recombinant protein production in Escherichia coli by temperature oscillations and post-induction nutrient feeding strategies.
Journal of Biotechnology,
167 (1),
47-55.
Editorial Material
48 - Caspeta,L., Buijs,N.A.A., Nielsen,J.. The role of biofuels in the future energy supply.
Energy & Environmental Science,
6 (4),
1077-1082.
*
Artículo
49 - Caspeta,L., Shoaie,S., Agren,R., Nookaew,I., Nielsen,J.. Genome-scale metabolic reconstructions of Pichia stipitis and Pichia pastoris and in silico evaluation of their potentials.
BMC Systems Biology,
6,
24.
*
Artículo
50 - Lara,A.R., Knabben,I., Regestein,L., Sassi,J., Caspeta,L., Ramirez,O.T., Buchs,J.. Comparison of oxygen enriched air vs. pressure cultivations to increase oxygen transfer and to scale-up plasmid DNA production fermentations.
Engineering in Life Sciences,
11 (4),
382-386.
Artículo
51 - Soto,R., Caspeta,L., Barron,B., Gosset,G., Ramirez,O.T., Lara,A.R.. High cell-density cultivation in batch mode for plasmid DNA production by a metabolically engineered E. coli strain with minimized overflow metabolism.
Biochemical Engineering Journal,
56 (3),
165-171.
Revisión
52 - Valdez-Cruz,N.A., Caspeta,L., Perez,N.O., Ramirez,O.T., Trujillo-Roldan,M.A.. Production of recombinant proteins in E. coli by the heat inducible expression system based on the phage lambda pL and/or pR promoters.
Microbial Cell Factories,
9 (1),
18.
Artículo
53 - Caspeta,L., FLORES,N., Perez,N.O., Bolivar,F., Ramirez,O.T.. The effect of heating rate on Escherichia coli metabolism, physiological stress, transcriptional response, and production of temperature-induced recombinant protein: a scale-down study.
Biotechnology and Bioengineering,
102 (2),
468-482.
54 - Caspeta Guadarrama, Luis. Escalamiento descendente del proceso de produccion de proteina heterologa por termoinduccion de cultivos de alta densidad celular de Escherichia coli : estudio de la respuesta transcripcional al choque termico .
Instituto de Biotecnologia,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Ramirez, Octavio T.
Artículo
55 - Lara,A.R., Caspeta,L., Gosset,G., Bolivar,F., Ramirez,O.T.. Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: An alternative to fed-batch cultures.
Biotechnology and Bioengineering,
99 (4),
893-901.
Artículo
56 - Villarreal,M.L., Caspeta,L., Quintero-Ramirez,R.. From the Mayan Highlands to the Bioreactors: In Vitro Tissue Culture of the Mexican Medicinal Plant Solanum chrysotrichum.
Electronic Journal of Integrative Biosciences,
3 (1),
20-28.
*
Artículo
57 - Caspeta,L., Quintero,R., Villarreal,M.L.. Novel airlift reactor fitting for hairy root cultures: developmental and performance studies.
Biotechnology Progress,
21 (3),
735-740.
*
Artículo
58 - Caspeta,L., Nieto,I., Zamilpa,A., Alvarez,L., Quintero,R., Villarreal,M.L.. Solanum chrysotrichum hairy root cultures: characterization, scale-up and production of five antifungal saponins for human use.
Planta Medica,
71 (11),
1084-1087.
*
- Teléfonos
-
Oficina +52 (777) 329-1601
desde la CDMX 562-27601
Red UNAM 27601