Dr. Luis Caspeta Guadarrama
Investigador
Biología de sistemas
Ingeniería metabólica
Número de registros: 2
- Activos
- Vencidos
- Evaluación de los nichos termo-ácidos de cepas de saccharomyces cerevisiae y de la importancia de estos en la producción de etanol y ácidos orgánicos, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2022 - 2023
- Manipulación del estado redox intracelular de saccharomyces cerevisiae para la producción de ácido succínico y etanol, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2019 - 2020
Doctorado, en Ciencias, Instituto de Biotecnología-UNAM
Maestría, Biotecnología, Centro de Investigación en Biotecnología-UAEM
Licenciatura, Ingeniería Química, Facultad de Ciencias Químicas e Ingeniería-UAEM
- Activos
- Graduados
-
Licenciatura
1 - Salas Navarrete, Prisciluis Caheri (2022). Estrategias para producir ácido succínico en Saccharomyces cerevisiae.
Centro de Investigación en Biotecnología,
Doctor en Ciencias Naturales,
UAEM.
*
Asesor: Caspeta Guadarrama, Luis
2 - Arenas Cedillo, Leon Fernando (2021). Produccion de esteres de esteroles en S. cerevisiae /.
Instituto de Biotecnología,
Maestría en Ciencias Bioquímicas,
UNAM.
Asesor: Caspeta, Luis
3 - Balderas Ramirez, Emiliano (2021). Conversión de xilosa a etanol en levaduras termo-tolerantes.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Caspeta, Luis
4 - Cortes Ocampo, Brenda Mabel (2021). Producción de Etanol por Sacarificación y Fermentación Simultánea de Residuos Pretratados de Zea Mays.
Facultad de Ciencias Biologicas,
Licenciatura en Biologia,
UAEM.
*
Asesor: Caspeta Guadarrama, Luis
5 - Cortés Ocampo, Brenda Mabel (2021). Producción de etanol por sacarificación y fermentación simultánea de residuos pretratados de Zea mays.
Facultad de Ciencias Biológicas,
Licenciatura en Biología,
UAEM.
*
Asesor: Caspeta Guadarrama, Luis
6 - Montes de Oca Miranda, Arturo Ivan (2019). Fisiología de cepas de Saccharomyces cerevisiae adaptadas a temperatura elevada y pH ácido.
Centro de Investigación en Biotecnología,
Meastría en Biotecnología,
UAEM.
*
Asesor: Caspeta Guadarrama, Luis
7 - Guadarrama Avila, Tania Marel (2018). Propagación del nemátodo entomopatógeno
Caenorhabditis brenneri.
Centro de Investigación en Biotecnología,
Maestría en Biotecnología,
UAEM.
*
Asesor: Caspeta Guadarrama, Luis, Hernández Velázquez, Víctor Manuel
Total de publicaciones: 31
- Tipo
- Fecha
Artículo
8 - Avila-Fernandez, A., Montiel,S., Rodriguez Alegria, M.E., Caspeta,L., Lopez-Munguia,A. (2023). Simultaneous enzyme production, Levan-type FOS synthesis and sugar by-products elimination using a recombinant Pichia pastoris strain expressing a levansucrase- endolevanase fusion enzyme.
Microbial Cell Factories,
22 (1),
18.
Artículo in press
9 - Salas-Navarrete,P.C., Rosas-Santiago,P., Suarez-Rodriguez,R., Martinez,A., Caspeta,L. (2023). Adaptive responses of yeast strains tolerant to acidic pH, acetate, and supraoptimal temperature.
Applied Microbiology and Biotechnology,
May 13 [Online ahead of print].
artículo
10 - Salas-Navarrete,P.C., Montees de Oca Miranda,A.I., Martinez,A., Caspeta,L. (2022). Evolutionary and reverse engineering to increase Saccharomyces cerevisiae tolerance to acetic acid, acidic pH, and high temperature.
Applied Microbiology and Biotechnology,
106 (1),
383-399.
Artículo
Artículo
12 - Caspeta,L., Kerkhoven,E.J., Martinez,A., Nielsen,J. (2021). The yeastGemMap: A process diagram to assist yeast systems-metabolic studies.
Biotechnology and Bioengineering,
118 (12),
4800-4814.
Artículo
13 - Caspeta, L., Coronel, J., de Oca, A. M., Abarca, E., Gonzalez, L., Martinez, A. (2019). Engineering high-gravity fermentations for ethanol production at elevated-temperature with Saccharomyces cerevisiae.
Biotechnology and Bioengineering,
116 (10),
2587-2597.
Artículo
14 - Bertrand,B., Trejo-Hernandez,M.R., Morales-Guzman,D., Caspeta,L., Suarez-Rodriguez R., Martinez-Morales,F. (2016). Functional expression, production, and biochemical characterization of a laccase using yeast surface display technology.
Fungal Biology,
120 (12),
1609-1622.
*
Artículo
15 - Caspeta,L., Chen,Y., Nielsen,J. (2016). Thermotolerant yeasts selected by adaptive evolution express heat stress response at 30 degrees C.
Scientific Reports,
6,
27003.
*
Revisión
16 - Caspeta,L., Castillo,T., Nielsen,J. (2015). Modifying Yeast Tolerance to Inhibitory Conditions of Ethanol Production Processes.
Frontiers in Bioengineering and Biotechnology,
3,
184.
*
Artículo
17 - Caspeta,L., Nielsen,J. (2015). Thermotolerant Yeast Strains Adapted by Laboratory Evolution Show Trade-Off at Ancestral Temperatures and Preadaptation to Other Stresses.
MBio,
6 (4),
e00431.
*
Artículo
18 - Caspeta,L., Caro-Bermudez,M.A., Ponce-Noyola,T., Martinez,A. (2014). Enzymatic hydrolysis at high-solids loadings for the conversion of agave bagasse to fuel ethanol.
Applied Energy,
113,
277-286.
Artículo
19 - Caspeta,L., Chen,Y., Ghiaci,P., Feizi,A., Buskov,S., Hallstrom,B.M., Petranovic,D., Nielsen,J. (2014). Biofuels. Altered sterol composition renders yeast thermotolerant.
Science,
346 (6205),
75-78.
*
Revisión
20 - Caspeta,L., Nielsen,J. (2013). Toward systems metabolic engineering of Aspergillus and Pichia species for the production of chemicals and biofuels.
Biotechnology Journal,
8 (5),
534-544.
*
Carta
21 - Caspeta,L., Nielsen,J. (2013). Economic and environmental impacts of microbial biodiesel.
Nature Biotechnology,
31 (9),
789-793.
*
Artículo
22 - Caspeta,L., Lara,A.R., Perez,N.O., FLORES,N., Bolivar,F., Ramirez,O.T. (2013). Enhancing thermo-induced recombinant protein production in Escherichia coli by temperature oscillations and post-induction nutrient feeding strategies.
Journal of Biotechnology,
167 (1),
47-55.
Artículo
23 - Caspeta,L., Shoaie,S., Agren,R., Nookaew,I., Nielsen,J. (2012). Genome-scale metabolic reconstructions of Pichia stipitis and Pichia pastoris and in silico evaluation of their potentials.
BMC Systems Biology,
6,
24.
*
Artículo
24 - Lara,A.R., Knabben,I., Regestein,L., Sassi,J., Caspeta,L., Ramirez,O.T., Buchs,J. (2011). Comparison of oxygen enriched air vs. pressure cultivations to increase oxygen transfer and to scale-up plasmid DNA production fermentations.
Engineering in Life Sciences,
11 (4),
382-386.
Artículo
25 - Soto,R., Caspeta,L., Barron,B., Gosset,G., Ramirez,O.T., Lara,A.R. (2011). High cell-density cultivation in batch mode for plasmid DNA production by a metabolically engineered E. coli strain with minimized overflow metabolism.
Biochemical Engineering Journal,
56 (3),
165-171.
Revisión
26 - Valdez-Cruz,N.A., Caspeta,L., Perez,N.O., Ramirez,O.T., Trujillo-Roldan,M.A. (2010). Production of recombinant proteins in E. coli by the heat inducible expression system based on the phage lambda pL and/or pR promoters.
Microbial Cell Factories,
9 (1),
18.
Artículo
27 - Caspeta,L., FLORES,N., Perez,N.O., Bolivar,F., Ramirez,O.T. (2009). The effect of heating rate on Escherichia coli metabolism, physiological stress, transcriptional response, and production of temperature-induced recombinant protein: a scale-down study.
Biotechnology and Bioengineering,
102 (2),
468-482.
Artículo
28 - Lara,A.R., Caspeta,L., Gosset,G., Bolivar,F., Ramirez,O.T. (2008). Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: An alternative to fed-batch cultures.
Biotechnology and Bioengineering,
99 (4),
893-901.
Artículo
29 - Villarreal,M.L., Caspeta,L., Quintero-Ramirez,R. (2008). From the Mayan Highlands to the Bioreactors: In Vitro Tissue Culture of the Mexican Medicinal Plant Solanum chrysotrichum.
Electronic Journal of Integrative Biosciences,
3 (1),
20-28.
*
Artículo
30 - Caspeta,L., Quintero,R., Villarreal,M.L. (2005). Novel airlift reactor fitting for hairy root cultures: developmental and performance studies.
Biotechnology Progress,
21 (3),
735-740.
*
Artículo
31 - Caspeta,L., Nieto,I., Zamilpa,A., Alvarez,L., Quintero,R., Villarreal,M.L. (2005). Solanum chrysotrichum hairy root cultures: characterization, scale-up and production of five antifungal saponins for human use.
Planta Medica,
71 (11),
1084-1087.
*
Internacional
32 - Caspeta,L., Salas-Navarrete,P.C. (2019). Reduction of the Saccharomyces cerevisiae Genome: Challenges and Perspectives. Minimal Cells: Design, Construction, Biotechnological Applications.
117-139,
Cham: Springer International Publishing.
Internacional
33 - Caspeta, L., Castillo, T. (2017). Systems Metabolic Engineering of Saccharomyces cerevisiae for Production of Biochemicals from Biomass. Engineering of Microorganisms for the Production of Chemicals and Biofuels from Renewable Resources.
31-65,
Cham.
*
Editorial material
34 - Caspeta,L., Bustamante,V.H. (2022). Inducing Self-Poisoning: a Feasible Antibacterial Strategy?.
Journal of Bacteriology,
204 (12),
e0041122.
Editorial material
35 - Fletcher,E., Chen,Y., Caspeta,L., Feizi,A. (2022). Editorial: Genomic strategies for efficient microbial cell factories.
Frontiers in Bioengineering and Biotechnology,
10,
962828.
nacional divulgación
36 - Balderas,E., Caspeta,L. (2021). Cadenas de valor: de la refinería actual a las biorrefinerías.
Biotecnologia en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM,
27,
31-35.
Editorial Material
37 - Caspeta,L., Buijs,N.A.A., Nielsen,J. (2013). The role of biofuels in the future energy supply.
Energy & Environmental Science,
6 (4),
1077-1082.
*
38 - Caspeta Guadarrama, Luis (2009). Escalamiento descendente del proceso de produccion de proteina heterologa por termoinduccion de cultivos de alta densidad celular de Escherichia coli : estudio de la respuesta transcripcional al choque termico .
Instituto de Biotecnologia,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Ramirez, Octavio T.
Artículo
39 - Avila-Fernandez, A., Montiel,S., Rodriguez Alegria, M.E., Caspeta,L., Lopez-Munguia,A.. Simultaneous enzyme production, Levan-type FOS synthesis and sugar by-products elimination using a recombinant Pichia pastoris strain expressing a levansucrase- endolevanase fusion enzyme.
Microbial Cell Factories,
22 (1),
18.
Artículo in press
40 - Salas-Navarrete,P.C., Rosas-Santiago,P., Suarez-Rodriguez,R., Martinez,A., Caspeta,L.. Adaptive responses of yeast strains tolerant to acidic pH, acetate, and supraoptimal temperature.
Applied Microbiology and Biotechnology,
May 13 [Online ahead of print].
artículo
41 - Salas-Navarrete,P.C., Montees de Oca Miranda,A.I., Martinez,A., Caspeta,L.. Evolutionary and reverse engineering to increase Saccharomyces cerevisiae tolerance to acetic acid, acidic pH, and high temperature.
Applied Microbiology and Biotechnology,
106 (1),
383-399.
Artículo
42 - Vera-Lopez-Portillo,F., Sierra-Ibarra,E., Vera-Estrella,R., Revah,S., Ramirez,O.T., Caspeta,L., Martinez,A.. Growth and phycocyanin production with Galdieria sulphuraria UTEX 2919 using xylose, glucose, and corn stover hydrolysates under heterotrophy and mixotrophy.
Algal Research,
65.
Editorial material
43 - Caspeta,L., Bustamante,V.H.. Inducing Self-Poisoning: a Feasible Antibacterial Strategy?.
Journal of Bacteriology,
204 (12),
e0041122.
Editorial material
44 - Fletcher,E., Chen,Y., Caspeta,L., Feizi,A.. Editorial: Genomic strategies for efficient microbial cell factories.
Frontiers in Bioengineering and Biotechnology,
10,
962828.
Artículo
45 - Caspeta,L., Kerkhoven,E.J., Martinez,A., Nielsen,J.. The yeastGemMap: A process diagram to assist yeast systems-metabolic studies.
Biotechnology and Bioengineering,
118 (12),
4800-4814.
nacional divulgación
46 - Balderas,E., Caspeta,L.. Cadenas de valor: de la refinería actual a las biorrefinerías.
Biotecnologia en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM,
27,
31-35.
Artículo
47 - Caspeta, L., Coronel, J., de Oca, A. M., Abarca, E., Gonzalez, L., Martinez, A.. Engineering high-gravity fermentations for ethanol production at elevated-temperature with Saccharomyces cerevisiae.
Biotechnology and Bioengineering,
116 (10),
2587-2597.
Internacional
48 - Caspeta,L., Salas-Navarrete,P.C.. Reduction of the Saccharomyces cerevisiae Genome: Challenges and Perspectives. Minimal Cells: Design, Construction, Biotechnological Applications.
117-139,
Cham: Springer International Publishing.
Internacional
49 - Caspeta, L., Castillo, T.. Systems Metabolic Engineering of Saccharomyces cerevisiae for Production of Biochemicals from Biomass. Engineering of Microorganisms for the Production of Chemicals and Biofuels from Renewable Resources.
31-65,
Cham.
*
Artículo
50 - Bertrand,B., Trejo-Hernandez,M.R., Morales-Guzman,D., Caspeta,L., Suarez-Rodriguez R., Martinez-Morales,F.. Functional expression, production, and biochemical characterization of a laccase using yeast surface display technology.
Fungal Biology,
120 (12),
1609-1622.
*
Artículo
51 - Caspeta,L., Chen,Y., Nielsen,J.. Thermotolerant yeasts selected by adaptive evolution express heat stress response at 30 degrees C.
Scientific Reports,
6,
27003.
*
Revisión
52 - Caspeta,L., Castillo,T., Nielsen,J.. Modifying Yeast Tolerance to Inhibitory Conditions of Ethanol Production Processes.
Frontiers in Bioengineering and Biotechnology,
3,
184.
*
Artículo
53 - Caspeta,L., Nielsen,J.. Thermotolerant Yeast Strains Adapted by Laboratory Evolution Show Trade-Off at Ancestral Temperatures and Preadaptation to Other Stresses.
MBio,
6 (4),
e00431.
*
Artículo
54 - Caspeta,L., Caro-Bermudez,M.A., Ponce-Noyola,T., Martinez,A.. Enzymatic hydrolysis at high-solids loadings for the conversion of agave bagasse to fuel ethanol.
Applied Energy,
113,
277-286.
Artículo
55 - Caspeta,L., Chen,Y., Ghiaci,P., Feizi,A., Buskov,S., Hallstrom,B.M., Petranovic,D., Nielsen,J.. Biofuels. Altered sterol composition renders yeast thermotolerant.
Science,
346 (6205),
75-78.
*
Revisión
56 - Caspeta,L., Nielsen,J.. Toward systems metabolic engineering of Aspergillus and Pichia species for the production of chemicals and biofuels.
Biotechnology Journal,
8 (5),
534-544.
*
Carta
57 - Caspeta,L., Nielsen,J.. Economic and environmental impacts of microbial biodiesel.
Nature Biotechnology,
31 (9),
789-793.
*
Artículo
58 - Caspeta,L., Lara,A.R., Perez,N.O., FLORES,N., Bolivar,F., Ramirez,O.T.. Enhancing thermo-induced recombinant protein production in Escherichia coli by temperature oscillations and post-induction nutrient feeding strategies.
Journal of Biotechnology,
167 (1),
47-55.
Editorial Material
59 - Caspeta,L., Buijs,N.A.A., Nielsen,J.. The role of biofuels in the future energy supply.
Energy & Environmental Science,
6 (4),
1077-1082.
*
Artículo
60 - Caspeta,L., Shoaie,S., Agren,R., Nookaew,I., Nielsen,J.. Genome-scale metabolic reconstructions of Pichia stipitis and Pichia pastoris and in silico evaluation of their potentials.
BMC Systems Biology,
6,
24.
*
Artículo
61 - Lara,A.R., Knabben,I., Regestein,L., Sassi,J., Caspeta,L., Ramirez,O.T., Buchs,J.. Comparison of oxygen enriched air vs. pressure cultivations to increase oxygen transfer and to scale-up plasmid DNA production fermentations.
Engineering in Life Sciences,
11 (4),
382-386.
Artículo
62 - Soto,R., Caspeta,L., Barron,B., Gosset,G., Ramirez,O.T., Lara,A.R.. High cell-density cultivation in batch mode for plasmid DNA production by a metabolically engineered E. coli strain with minimized overflow metabolism.
Biochemical Engineering Journal,
56 (3),
165-171.
Revisión
63 - Valdez-Cruz,N.A., Caspeta,L., Perez,N.O., Ramirez,O.T., Trujillo-Roldan,M.A.. Production of recombinant proteins in E. coli by the heat inducible expression system based on the phage lambda pL and/or pR promoters.
Microbial Cell Factories,
9 (1),
18.
Artículo
64 - Caspeta,L., FLORES,N., Perez,N.O., Bolivar,F., Ramirez,O.T.. The effect of heating rate on Escherichia coli metabolism, physiological stress, transcriptional response, and production of temperature-induced recombinant protein: a scale-down study.
Biotechnology and Bioengineering,
102 (2),
468-482.
65 - Caspeta Guadarrama, Luis. Escalamiento descendente del proceso de produccion de proteina heterologa por termoinduccion de cultivos de alta densidad celular de Escherichia coli : estudio de la respuesta transcripcional al choque termico .
Instituto de Biotecnologia,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Ramirez, Octavio T.
Artículo
66 - Lara,A.R., Caspeta,L., Gosset,G., Bolivar,F., Ramirez,O.T.. Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: An alternative to fed-batch cultures.
Biotechnology and Bioengineering,
99 (4),
893-901.
Artículo
67 - Villarreal,M.L., Caspeta,L., Quintero-Ramirez,R.. From the Mayan Highlands to the Bioreactors: In Vitro Tissue Culture of the Mexican Medicinal Plant Solanum chrysotrichum.
Electronic Journal of Integrative Biosciences,
3 (1),
20-28.
*
Artículo
68 - Caspeta,L., Quintero,R., Villarreal,M.L.. Novel airlift reactor fitting for hairy root cultures: developmental and performance studies.
Biotechnology Progress,
21 (3),
735-740.
*
Artículo
69 - Caspeta,L., Nieto,I., Zamilpa,A., Alvarez,L., Quintero,R., Villarreal,M.L.. Solanum chrysotrichum hairy root cultures: characterization, scale-up and production of five antifungal saponins for human use.
Planta Medica,
71 (11),
1084-1087.
*
- Teléfonos
-
Oficina +52 (777) 329-1601
desde la CDMX 562-27601
Red UNAM 27601