Dr. Luis Caspeta Guadarrama
Ex-colaborador y/o ex-alumno
Total de publicaciones: 37
- Tipo
- Fecha
Artículo
1 - Martinez,J.A., Bouchat,R., Gallet de St Aurin,T., Martinez,L.M., Caspeta,L., Telek,S., Zicler,A., Gosset,G., Delvigne,F. (2025). Automated adjustment of metabolic niches enables the control of natural and engineered microbial co-cultures.
Trends in Biotechnology,
43 (5),
1116-1139.
Artículo
2 - Molina-Vazquez,E.R., Caspeta,L., Gosset,G., Martinez,A. (2025). Tailoring Escherichia coli BL21 (DE3) for preferential xylose utilization via metabolic and regulatory engineering.
Applied Microbiology and Biotechnology,
109 (1),
54.
Artículo
3 - Perez-Morales,G., Martinez-Conde,K.V., Caspeta,L., Merino,E., Cevallos,M.A., Gosset,G., Martinez,A. (2025). Thermally adapted Escherichia coli keeps transcriptomic response during temperature upshift exposure.
Applied Microbiology and Biotechnology,
109 (1),
120.
Artículo
4 - Perez-Morales,G., Caspeta,L., Merino,E., Cevallos,M.A., Gosset,G., Martinez,A. (2024). Simultaneous saccharification and fermentation for D-lactic acid production using a metabolically engineered Escherichia coli adapted to high temperature.
Biotechnology for Biofuels and Bioproducts,
17 (1),
132.
Artículo
5 - Avila-Fernandez, A., Montiel,S., Rodriguez Alegria, M.E., Caspeta,L., Lopez-Munguia,A. (2023). Simultaneous enzyme production, Levan-type FOS synthesis and sugar by-products elimination using a recombinant Pichia pastoris strain expressing a levansucrase- endolevanase fusion enzyme.
Microbial Cell Factories,
22 (1),
18.
Artículo
6 - Salas-Navarrete,P.C., Rosas-Santiago,P., Suarez-Rodriguez,R., Martinez,A., Caspeta,L. (2023). Adaptive responses of yeast strains tolerant to acidic pH, acetate, and supraoptimal temperature.
Applied Microbiology and Biotechnology,
107 (12),
4051-4068.
artículo
7 - Salas-Navarrete,P.C., Montees de Oca Miranda,A.I., Martinez,A., Caspeta,L. (2022). Evolutionary and reverse engineering to increase Saccharomyces cerevisiae tolerance to acetic acid, acidic pH, and high temperature.
Applied Microbiology and Biotechnology,
106 (1),
383-399.
Artículo
Artículo
9 - Caspeta,L., Kerkhoven,E.J., Martinez,A., Nielsen,J. (2021). The yeastGemMap: A process diagram to assist yeast systems-metabolic studies.
Biotechnology and Bioengineering,
118 (12),
4800-4814.
Artículo
10 - Caspeta, L., Coronel, J., de Oca, A. M., Abarca, E., Gonzalez, L., Martinez, A. (2019). Engineering high-gravity fermentations for ethanol production at elevated-temperature with Saccharomyces cerevisiae.
Biotechnology and Bioengineering,
116 (10),
2587-2597.
Artículo
11 - Bertrand,B., Trejo-Hernandez,M.R., Morales-Guzman,D., Caspeta,L., Suarez-Rodriguez R., Martinez-Morales,F. (2016). Functional expression, production, and biochemical characterization of a laccase using yeast surface display technology.
Fungal Biology,
120 (12),
1609-1622.
*
Artículo
12 - Caspeta,L., Chen,Y., Nielsen,J. (2016). Thermotolerant yeasts selected by adaptive evolution express heat stress response at 30 degrees C.
Scientific Reports,
6,
27003.
*
Revisión
13 - Caspeta,L., Castillo,T., Nielsen,J. (2015). Modifying Yeast Tolerance to Inhibitory Conditions of Ethanol Production Processes.
Frontiers in Bioengineering and Biotechnology,
3,
184.
*
Artículo
14 - Caspeta,L., Nielsen,J. (2015). Thermotolerant Yeast Strains Adapted by Laboratory Evolution Show Trade-Off at Ancestral Temperatures and Preadaptation to Other Stresses.
MBio,
6 (4),
e00431.
*
Artículo
15 - Caspeta,L., Caro-Bermudez,M.A., Ponce-Noyola,T., Martinez,A. (2014). Enzymatic hydrolysis at high-solids loadings for the conversion of agave bagasse to fuel ethanol.
Applied Energy,
113,
277-286.
Artículo
16 - Caspeta,L., Chen,Y., Ghiaci,P., Feizi,A., Buskov,S., Hallstrom,B.M., Petranovic,D., Nielsen,J. (2014). Biofuels. Altered sterol composition renders yeast thermotolerant.
Science,
346 (6205),
75-78.
*
Revisión
17 - Caspeta,L., Nielsen,J. (2013). Toward systems metabolic engineering of Aspergillus and Pichia species for the production of chemicals and biofuels.
Biotechnology Journal,
8 (5),
534-544.
*
Carta
18 - Caspeta,L., Nielsen,J. (2013). Economic and environmental impacts of microbial biodiesel.
Nature Biotechnology,
31 (9),
789-793.
*
Artículo
19 - Caspeta,L., Lara,A.R., Perez,N.O., FLORES,N., Bolivar,F., Ramirez,O.T. (2013). Enhancing thermo-induced recombinant protein production in Escherichia coli by temperature oscillations and post-induction nutrient feeding strategies.
Journal of Biotechnology,
167 (1),
47-55.
Artículo
20 - Caspeta,L., Shoaie,S., Agren,R., Nookaew,I., Nielsen,J. (2012). Genome-scale metabolic reconstructions of Pichia stipitis and Pichia pastoris and in silico evaluation of their potentials.
BMC Systems Biology,
6,
24.
*
Artículo
21 - Lara,A.R., Knabben,I., Regestein,L., Sassi,J., Caspeta,L., Ramirez,O.T., Buchs,J. (2011). Comparison of oxygen enriched air vs. pressure cultivations to increase oxygen transfer and to scale-up plasmid DNA production fermentations.
Engineering in Life Sciences,
11 (4),
382-386.
Artículo
22 - Soto,R., Caspeta,L., Barron,B., Gosset,G., Ramirez,O.T., Lara,A.R. (2011). High cell-density cultivation in batch mode for plasmid DNA production by a metabolically engineered E. coli strain with minimized overflow metabolism.
Biochemical Engineering Journal,
56 (3),
165-171.
Revisión
23 - Valdez-Cruz,N.A., Caspeta,L., Perez,N.O., Ramirez,O.T., Trujillo-Roldan,M.A. (2010). Production of recombinant proteins in E. coli by the heat inducible expression system based on the phage lambda pL and/or pR promoters.
Microbial Cell Factories,
9 (1),
18.
Artículo
24 - Caspeta,L., FLORES,N., Perez,N.O., Bolivar,F., Ramirez,O.T. (2009). The effect of heating rate on Escherichia coli metabolism, physiological stress, transcriptional response, and production of temperature-induced recombinant protein: a scale-down study.
Biotechnology and Bioengineering,
102 (2),
468-482.
Artículo
25 - Lara,A.R., Caspeta,L., Gosset,G., Bolivar,F., Ramirez,O.T. (2008). Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: An alternative to fed-batch cultures.
Biotechnology and Bioengineering,
99 (4),
893-901.
Artículo
26 - Villarreal,M.L., Caspeta,L., Quintero-Ramirez,R. (2008). From the Mayan Highlands to the Bioreactors: In Vitro Tissue Culture of the Mexican Medicinal Plant Solanum chrysotrichum.
Electronic Journal of Integrative Biosciences,
3 (1),
20-28.
*
Artículo
27 - Caspeta,L., Quintero,R., Villarreal,M.L. (2005). Novel airlift reactor fitting for hairy root cultures: developmental and performance studies.
Biotechnology Progress,
21 (3),
735-740.
*
Artículo
28 - Caspeta,L., Nieto,I., Zamilpa,A., Alvarez,L., Quintero,R., Villarreal,M.L. (2005). Solanum chrysotrichum hairy root cultures: characterization, scale-up and production of five antifungal saponins for human use.
Planta Medica,
71 (11),
1084-1087.
*
Internacional
29 - Caspeta,L., Salas-Navarrete,P.C. (2019). Reduction of the Saccharomyces cerevisiae Genome: Challenges and Perspectives. Minimal Cells: Design, Construction, Biotechnological Applications.
117-139,
Cham: Springer International Publishing.
Internacional
30 - Caspeta, L., Castillo, T. (2017). Systems Metabolic Engineering of Saccharomyces cerevisiae for Production of Biochemicals from Biomass. Engineering of Microorganisms for the Production of Chemicals and Biofuels from Renewable Resources.
31-65,
Cham.
*
Preprint
31 - Martinez-Alvarez,J.A., Bouchat,R., Gallet de St Aurin,T., Martinez,L.M., Caspeta,L., Telek,S., Zicler,A., Gosset,G., Delvigne,F. (2024). Automated adjustment of metabolic niches enables the control of natural and engineered microbial co-cultures.
bioRxiv,
Preprint posted May 14.
Preprint
32 - Caspeta,L., Salas-Navarrete,P.C., Rosas-Santiago,P., Suarez-Rodriguez,R., Martinez,A. (2023). Adaptive responses of evolved Saccharomyces cerevisiae strains tolerant to acidic pH, acetic acid, and supraoptimal temperature.
Authorea,
Preprint Feb 9.
Editorial material
33 - Caspeta,L., Bustamante,V.H. (2022). Inducing Self-Poisoning: a Feasible Antibacterial Strategy?.
Journal of Bacteriology,
204 (12),
e0041122.
Editorial material
34 - Fletcher,E., Chen,Y., Caspeta,L., Feizi,A. (2022). Editorial: Genomic strategies for efficient microbial cell factories.
Frontiers in Bioengineering and Biotechnology,
10,
962828.
nacional divulgación
35 - Balderas,E., Caspeta,L. (2021). Cadenas de valor: de la refinería actual a las biorrefinerías.
Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM,
27,
31-35.
Editorial Material
36 - Caspeta,L., Buijs,N.A.A., Nielsen,J. (2013). The role of biofuels in the future energy supply.
Energy & Environmental Science,
6 (4),
1077-1082.
*
37 - Caspeta Guadarrama, Luis (2009). Escalamiento descendente del proceso de produccion de proteina heterologa por termoinduccion de cultivos de alta densidad celular de Escherichia coli : estudio de la respuesta transcripcional al choque termico .
Instituto de Biotecnologia,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Ramirez, Octavio T.
Artículo
38 - Martinez,J.A., Bouchat,R., Gallet de St Aurin,T., Martinez,L.M., Caspeta,L., Telek,S., Zicler,A., Gosset,G., Delvigne,F.. Automated adjustment of metabolic niches enables the control of natural and engineered microbial co-cultures.
Trends in Biotechnology,
43 (5),
1116-1139.
Artículo
39 - Molina-Vazquez,E.R., Caspeta,L., Gosset,G., Martinez,A.. Tailoring Escherichia coli BL21 (DE3) for preferential xylose utilization via metabolic and regulatory engineering.
Applied Microbiology and Biotechnology,
109 (1),
54.
Artículo
40 - Perez-Morales,G., Martinez-Conde,K.V., Caspeta,L., Merino,E., Cevallos,M.A., Gosset,G., Martinez,A.. Thermally adapted Escherichia coli keeps transcriptomic response during temperature upshift exposure.
Applied Microbiology and Biotechnology,
109 (1),
120.
Artículo
41 - Perez-Morales,G., Caspeta,L., Merino,E., Cevallos,M.A., Gosset,G., Martinez,A.. Simultaneous saccharification and fermentation for D-lactic acid production using a metabolically engineered Escherichia coli adapted to high temperature.
Biotechnology for Biofuels and Bioproducts,
17 (1),
132.
Preprint
42 - Martinez-Alvarez,J.A., Bouchat,R., Gallet de St Aurin,T., Martinez,L.M., Caspeta,L., Telek,S., Zicler,A., Gosset,G., Delvigne,F.. Automated adjustment of metabolic niches enables the control of natural and engineered microbial co-cultures.
bioRxiv,
Preprint posted May 14.
Artículo
43 - Avila-Fernandez, A., Montiel,S., Rodriguez Alegria, M.E., Caspeta,L., Lopez-Munguia,A.. Simultaneous enzyme production, Levan-type FOS synthesis and sugar by-products elimination using a recombinant Pichia pastoris strain expressing a levansucrase- endolevanase fusion enzyme.
Microbial Cell Factories,
22 (1),
18.
Artículo
44 - Salas-Navarrete,P.C., Rosas-Santiago,P., Suarez-Rodriguez,R., Martinez,A., Caspeta,L.. Adaptive responses of yeast strains tolerant to acidic pH, acetate, and supraoptimal temperature.
Applied Microbiology and Biotechnology,
107 (12),
4051-4068.
Preprint
45 - Caspeta,L., Salas-Navarrete,P.C., Rosas-Santiago,P., Suarez-Rodriguez,R., Martinez,A.. Adaptive responses of evolved Saccharomyces cerevisiae strains tolerant to acidic pH, acetic acid, and supraoptimal temperature.
Authorea,
Preprint Feb 9.
artículo
46 - Salas-Navarrete,P.C., Montees de Oca Miranda,A.I., Martinez,A., Caspeta,L.. Evolutionary and reverse engineering to increase Saccharomyces cerevisiae tolerance to acetic acid, acidic pH, and high temperature.
Applied Microbiology and Biotechnology,
106 (1),
383-399.
Artículo
47 - Vera-Lopez-Portillo,F., Sierra-Ibarra,E., Vera-Estrella,R., Revah,S., Ramirez,O.T., Caspeta,L., Martinez,A.. Growth and phycocyanin production with Galdieria sulphuraria UTEX 2919 using xylose, glucose, and corn stover hydrolysates under heterotrophy and mixotrophy.
Algal Research,
65.
Editorial material
48 - Caspeta,L., Bustamante,V.H.. Inducing Self-Poisoning: a Feasible Antibacterial Strategy?.
Journal of Bacteriology,
204 (12),
e0041122.
Editorial material
49 - Fletcher,E., Chen,Y., Caspeta,L., Feizi,A.. Editorial: Genomic strategies for efficient microbial cell factories.
Frontiers in Bioengineering and Biotechnology,
10,
962828.
Artículo
50 - Caspeta,L., Kerkhoven,E.J., Martinez,A., Nielsen,J.. The yeastGemMap: A process diagram to assist yeast systems-metabolic studies.
Biotechnology and Bioengineering,
118 (12),
4800-4814.
nacional divulgación
51 - Balderas,E., Caspeta,L.. Cadenas de valor: de la refinería actual a las biorrefinerías.
Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM,
27,
31-35.
Artículo
52 - Caspeta, L., Coronel, J., de Oca, A. M., Abarca, E., Gonzalez, L., Martinez, A.. Engineering high-gravity fermentations for ethanol production at elevated-temperature with Saccharomyces cerevisiae.
Biotechnology and Bioengineering,
116 (10),
2587-2597.
Internacional
53 - Caspeta,L., Salas-Navarrete,P.C.. Reduction of the Saccharomyces cerevisiae Genome: Challenges and Perspectives. Minimal Cells: Design, Construction, Biotechnological Applications.
117-139,
Cham: Springer International Publishing.
Internacional
54 - Caspeta, L., Castillo, T.. Systems Metabolic Engineering of Saccharomyces cerevisiae for Production of Biochemicals from Biomass. Engineering of Microorganisms for the Production of Chemicals and Biofuels from Renewable Resources.
31-65,
Cham.
*
Artículo
55 - Bertrand,B., Trejo-Hernandez,M.R., Morales-Guzman,D., Caspeta,L., Suarez-Rodriguez R., Martinez-Morales,F.. Functional expression, production, and biochemical characterization of a laccase using yeast surface display technology.
Fungal Biology,
120 (12),
1609-1622.
*
Artículo
56 - Caspeta,L., Chen,Y., Nielsen,J.. Thermotolerant yeasts selected by adaptive evolution express heat stress response at 30 degrees C.
Scientific Reports,
6,
27003.
*
Revisión
57 - Caspeta,L., Castillo,T., Nielsen,J.. Modifying Yeast Tolerance to Inhibitory Conditions of Ethanol Production Processes.
Frontiers in Bioengineering and Biotechnology,
3,
184.
*
Artículo
58 - Caspeta,L., Nielsen,J.. Thermotolerant Yeast Strains Adapted by Laboratory Evolution Show Trade-Off at Ancestral Temperatures and Preadaptation to Other Stresses.
MBio,
6 (4),
e00431.
*
Artículo
59 - Caspeta,L., Caro-Bermudez,M.A., Ponce-Noyola,T., Martinez,A.. Enzymatic hydrolysis at high-solids loadings for the conversion of agave bagasse to fuel ethanol.
Applied Energy,
113,
277-286.
Artículo
60 - Caspeta,L., Chen,Y., Ghiaci,P., Feizi,A., Buskov,S., Hallstrom,B.M., Petranovic,D., Nielsen,J.. Biofuels. Altered sterol composition renders yeast thermotolerant.
Science,
346 (6205),
75-78.
*
Revisión
61 - Caspeta,L., Nielsen,J.. Toward systems metabolic engineering of Aspergillus and Pichia species for the production of chemicals and biofuels.
Biotechnology Journal,
8 (5),
534-544.
*
Carta
62 - Caspeta,L., Nielsen,J.. Economic and environmental impacts of microbial biodiesel.
Nature Biotechnology,
31 (9),
789-793.
*
Artículo
63 - Caspeta,L., Lara,A.R., Perez,N.O., FLORES,N., Bolivar,F., Ramirez,O.T.. Enhancing thermo-induced recombinant protein production in Escherichia coli by temperature oscillations and post-induction nutrient feeding strategies.
Journal of Biotechnology,
167 (1),
47-55.
Editorial Material
64 - Caspeta,L., Buijs,N.A.A., Nielsen,J.. The role of biofuels in the future energy supply.
Energy & Environmental Science,
6 (4),
1077-1082.
*
Artículo
65 - Caspeta,L., Shoaie,S., Agren,R., Nookaew,I., Nielsen,J.. Genome-scale metabolic reconstructions of Pichia stipitis and Pichia pastoris and in silico evaluation of their potentials.
BMC Systems Biology,
6,
24.
*
Artículo
66 - Lara,A.R., Knabben,I., Regestein,L., Sassi,J., Caspeta,L., Ramirez,O.T., Buchs,J.. Comparison of oxygen enriched air vs. pressure cultivations to increase oxygen transfer and to scale-up plasmid DNA production fermentations.
Engineering in Life Sciences,
11 (4),
382-386.
Artículo
67 - Soto,R., Caspeta,L., Barron,B., Gosset,G., Ramirez,O.T., Lara,A.R.. High cell-density cultivation in batch mode for plasmid DNA production by a metabolically engineered E. coli strain with minimized overflow metabolism.
Biochemical Engineering Journal,
56 (3),
165-171.
Revisión
68 - Valdez-Cruz,N.A., Caspeta,L., Perez,N.O., Ramirez,O.T., Trujillo-Roldan,M.A.. Production of recombinant proteins in E. coli by the heat inducible expression system based on the phage lambda pL and/or pR promoters.
Microbial Cell Factories,
9 (1),
18.
Artículo
69 - Caspeta,L., FLORES,N., Perez,N.O., Bolivar,F., Ramirez,O.T.. The effect of heating rate on Escherichia coli metabolism, physiological stress, transcriptional response, and production of temperature-induced recombinant protein: a scale-down study.
Biotechnology and Bioengineering,
102 (2),
468-482.
70 - Caspeta Guadarrama, Luis. Escalamiento descendente del proceso de produccion de proteina heterologa por termoinduccion de cultivos de alta densidad celular de Escherichia coli : estudio de la respuesta transcripcional al choque termico .
Instituto de Biotecnologia,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Ramirez, Octavio T.
Artículo
71 - Lara,A.R., Caspeta,L., Gosset,G., Bolivar,F., Ramirez,O.T.. Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: An alternative to fed-batch cultures.
Biotechnology and Bioengineering,
99 (4),
893-901.
Artículo
72 - Villarreal,M.L., Caspeta,L., Quintero-Ramirez,R.. From the Mayan Highlands to the Bioreactors: In Vitro Tissue Culture of the Mexican Medicinal Plant Solanum chrysotrichum.
Electronic Journal of Integrative Biosciences,
3 (1),
20-28.
*
Artículo
73 - Caspeta,L., Quintero,R., Villarreal,M.L.. Novel airlift reactor fitting for hairy root cultures: developmental and performance studies.
Biotechnology Progress,
21 (3),
735-740.
*
Artículo
74 - Caspeta,L., Nieto,I., Zamilpa,A., Alvarez,L., Quintero,R., Villarreal,M.L.. Solanum chrysotrichum hairy root cultures: characterization, scale-up and production of five antifungal saponins for human use.
Planta Medica,
71 (11),
1084-1087.
*