M.C. Josefina Guzman Aparicio

M.C. Josefina Guzman Aparicio
Técnica Académica Titular C Tiempo Completo

Líneas Investigación
Logros Obtenidos
Publicaciones

Líneas Investigación

Biología Molecular, Bioquímica y Fisiología de Bacterias

1 - Velazquez-Sanchez,C., Vences-Guzman,M.A., Moreno,S., Tinoco-Valencia,R., Espin,G., Guzman,J., Sahonero-Canavesi,D.X., Sohlenkamp,C., Segura,D. (2021). PsrA positively regulates the unsaturated fatty acid synthesis operon fabAB in Azotobacter vinelandii. Microbiological Research, 249, 126775.

Artículo

2 - Ahumada-Manuel,C.L., Martinez-Ortiz,I.C., Hsueh,B.Y., Guzman,J., Waters,C.M., Zamorano-Sanchez,D., Espin,G, Nunez,C. (2020). Increased c-di-GMP Levels Lead to the Production of Alginates of High Molecular Mass in Azotobacter vinelandii. Journal of Bacteriology, 202 (24), e00135-20, e00134-20.

Artículo

3 - Martinez-Ortiz,I.C., Ahumada-Manuel,C.L., Hsueh,B.Y., Guzman,J., Moreno,S., Cocotl-Yanez,M., Waters,C.M., Zamorano-Sanchez,D., Espin,G., Nunez,C (2020). Cyclic di-GMP-Mediated Regulation of Extracellular Mannuronan C-5 Epimerases Is Essential for Cyst Formation in Azotobacter vinelandii. Journal of Bacteriology, 202 (24), e00135-20.

Artículo

4 - Adaya, L., Millan, M., Pena, C., Jendrossek, D., Espin, G., Tinoco-Valencia, R., Guzman, J., Pfeiffer, D., Segura, D. (2018). Inactivation of an intracellular poly-3-hydroxybutyrate depolymerase of Azotobacter vinelandii allows to obtain a polymer of uniform high molecular mass. Applied Microbiology and Biotechnology, 102 (6), 2693-2707.

Artículo

5 - Martinez-Valenzuela,M., Guzman,J., Moreno,S., Ahumada-Manuel,C.L., Espin,G., Nunez,C. (2018). Expression of the sRNAs CrcZ and CrcY modulate the strength of carbon catabolite repression under diazotrophic or non-diazotrophic growing conditions in Azotobacter vinelandii. PLoS ONE, 13 (12), e0208975.

Artículo

6 - Rosas-Galvan, N.S., Martinez-Morales, F., Marquina-Bahena, S., Tinoco-Valencia, R., Serrano-Carreon, L., Bertrand, B., Leon-Rodriguez, R., Guzman-Aparicio, J., ALvarez-Berber, L., Trejo-Hernandez, M.D.R. (2018). Improved production, purification and characterization of biosurfactants produced by Serratia marcescens SM3 and its isogenic SMRG-5 strain. Biotechnology and Applied Biochemistry, 65 (5), 690-700.

Artículo

7 - Ahumada-Manuel, C.L., Guzman, J., Pena, C., Quiroz-Rocha, E., Espin, G., Nunez, C. (2017). The signaling protein MucG negatively affects the production and the molecular mass of alginate in Azotobacter vinelandii. Applied Microbiology and Biotechnology, 101 (4), 1521-1534.

Artículo

8 - Quiroz-Rocha, E., Bonilla-Badia, F., Garcia-Aguilar, V., Lopez-Pliego, L., Serrano-Roman, J., Cocotl-Yanez, M., Guzman, J., Ahumada-Manuel, C.L., Muriel-Millan, L.F., Castaneda, M., Espin, G., Nunez, C. (2017). Two-component system CbrA/CbrB controls alginate production in Azotobacter vinelandii. Microbiology, 163 (7), 1105-1115.

Artículo

9 - Quiroz-Rocha, E., Moreno, R., Hernandez-Ortiz, A., Fragoso-Jimenez, J.C., Muriel-Millan, L.F., Guzman, J., Espin, G., Rojo, F., Nunez, C. (2017). Glucose uptake in Azotobacter vinelandii occurs through a GluP transporter that is under the control of the CbrA/CbrB and Hfq-Crc systems. Scientific Reports, 7 (1), 858.

Artículo

10 - Romero,Y., Guzman,J., Moreno,S., Cocotl-Yanez,M., Vences-Guzman,M.A., Castaneda,M., Espin,G., Segura,D. (2016). The GacS/A-RsmA Signal Transduction Pathway Controls the Synthesis of Alkylresorcinol Lipids that Replace Membrane Phospholipids during Encystment of Azotobacter vinelandii SW136. PLoS ONE, 11 (4), e0153266.

Artículo

11 - Nunez,C., Pena,C., Kloeckner,W., Hernandez-Eligio,A., Bogachev,A.V., Moreno,S., Guzman,J., Buchs,J., Espin,G. (2013). Alginate synthesis in Azotobacter vinelandii is increased by reducing the intracellular production of ubiquinone. Applied Microbiology and Biotechnology, 97 (6), 2503-2512.

Artículo

12 - Romero,Y., Moreno,S., Guzman,J., Espin,G., Segura,D. (2013). The Sigma Factor RpoS Controls Alkylresorcinol Synthesis Through ArpR, a LysR-Type Regulatory Protein During Encystment of Azotobacter vinelandii. Journal of Bacteriology, 195 (8), 1834-1844.

Artículo

13 - Nunez,C., Bogachev,A.V., Guzman,G., Tello,I., Guzman,J., Espin,G. (2009). The Na+-translocating NADH : ubiquinone oxidoreductase of Azotobacter vinelandii negatively regulates alginate synthesis. Microbiology, 155 (Pt 1), 249-256.

Artículo

14 - Gaona,G., Nunez,C., Goldberg,J.B., Linford,A.S., Najera,R., Castaneda,M., Guzman,J., Espin,G., Soberon-Chavez,G. (2004). Characterization of the Azotobacter vinelandii algC gene involved in alginate and lipopolysaccharide production. Fems Microbiology Letters, 238 (1), 199-206.

Artículo

15 - Segura,D., Guzman,J., Espin,G. (2003). Azotobacter vinelandii mutants that overproduce poly-beta-hydroxybutyrate or alginate. Applied Microbiology and Biotechnology, 63 (2), 159-163.

Artículo

16 - Peralta-Gil,M., Segura,D., Guzman,J., Servin-Gonzalez,L., Espin,G. (2002). Expression of the Azotobacter vinelandii Poly-beta-Hydroxybutyrate Biosynthetic phbBAC Operon Is Driven by Two Overlapping Promoters and Is Dependent on the Transcriptional Activator PhbR. Journal of Bacteriology, 184 (20), 5672-5677.

Artículo

17 - Gama-Castro,S., Nunez,C., Segura,D., Moreno,S., Guzman,J., Espin,G. (2001). Azotobacter vinelandii Aldehyde Dehydrogenase Regulated by sigma(54): Role in Alcohol Catabolism and Encystment. Journal of Bacteriology, 183 (21), 6169-6174.

Artículo

18 - Castaneda,M., Guzman,J., Moreno,S., Espin,G. (2000). The GacS sensor kinase regulates alginate and poly-beta-hydroxybutyrate production in Azotobacter vinelandii. Journal of Bacteriology, 182 (9), 2624-2628.

Artículo

19 - Nunez,C., Leon,R., Guzman,J., Espin,G., Soberon-Chavez,G. (2000). Role of Azotobacter vinelandii mucA and mucC gene products in alginate production. Journal of Bacteriology, 182 (23), 6550-6556.

Artículo

20 - Vazquez,A., Moreno,S., Guzman,J., Alvarado,A., Espin,G. (1999). Transcriptional organization of the Azotobacter vinelandii algGXLVIFA genes: characterization of algF mutants. Gene, 232 (2), 217-222.

Artículo

21 - Moreno,S., Najera,R., Guzman,J., Soberon-Chavez,G., Espin,G. (1998). Role of alternative sigma factor algU in encystment of Azotobacter vinelandii. Journal of Bacteriology, 180 (10), 2766-2769.

Artículo

22 - Caba,J.M., Guzman,J., Ortega,J.L., Lluch,C., Lara,M., Ligero,F. (1997). Purification and partial characterization of glutamine synthetase from root nodules of faba bean. Ars Pharmaceutica, 38 (4), 345-356.

Artículo

23 - Martinez,P., Guzman,J., Espin,G. (1997). A mutation impairing alginate production increased accumulation of poly-beta-hydroxybutyrate in Azotobacter vinelandii. Biotechnology Letters, 19 (9), 909-911.

Artículo

24 - Mejia-Ruiz,H., Moreno,S., Guzman,J., Najera,R., Leon,R., Soberon-Chavez,G., Espin,G. (1997). Isolation and characterization of an Azotobacter vinelandii algK mutant. Fems Microbiology Letters, 156 (1), 101-106.

Artículo

25 - Mejia-Ruiz,H., Guzman,J., Moreno,S., Soberon-Chavez,G., Espin,G. (1997). The Azotobacter vinelandii alg8 and alg44 genes are essential for alginate synthesis and can be transcribed from an algD-independent promoter. Gene, 199 (1-2), 271-277.

Revisión

26 - Espin,G., Moreno,S., Guzman,J. (1994). Molecular genetics of the glutamine synthetases in Rhizobium species. Critical Reviews in Microbiology, 20 (2), 117-123.

Note

27 - Noguez,R., Moreno,S., Guzman,J., Espin,G. (1994). The effect of the nitrogen and ntrC on the adenylylation of glutamine synthetase I in Rhizobium etli. Canadian Journal of Microbiology, 40 (11), 965-968.

Note

28 - Moreno,S., Meza,R., Guzman,J., Carabez,A., Espin,G. (1991). The glnA Gene of Rhizobium leguminosarum bv. phaseoli and Its Role In Symbiosis. Molecular Plant-Microbe Interactions, 4 (6), 619-622.

Note

29 - Sanchez,F., Calva,E., Campomanes,M., Blanco,L., Guzman,J., Saborio,J.L., Palacios,R. (1980). Heterogeneity of glutamine synthetase polypeptides in Neurospora crassa. Journal of Biological Chemistry, 255 (6), 2231-2234. *

Ver publicaciones anteriores

Capítulos

Internacional

30 - Mora,J., Davila,G., Espin,G., Gonzalez,A., Guzman,J., Hernandez.G., Hummelt,G., Lara,M., Martinez,E., Mora,Y., Romero,D. (1980). Glutamine Metabolism in Neurospora crassa. Glutamine: Metabolism, Enzymology, and Regulation. 185-211. *

Tesis

31 - Guzman Aparicio, Josefina (1993). Rhizobium leguminosarum biovar phaseoli una bacteria simbiotica o patogena, una mutacion en glnT hace la diferencia . Facultad de Quimica, Maestro en Ciencias Quimicas (Bioquimica), UNAM. *

Asesor: Espin Ocampo, Elda Guadalupe

2021

Artículo

32 - Velazquez-Sanchez,C., Vences-Guzman,M.A., Moreno,S., Tinoco-Valencia,R., Espin,G., Guzman,J., Sahonero-Canavesi,D.X., Sohlenkamp,C., Segura,D.. PsrA positively regulates the unsaturated fatty acid synthesis operon fabAB in Azotobacter vinelandii. Microbiological Research, 249, 126775.

2020

Artículo

33 - Ahumada-Manuel,C.L., Martinez-Ortiz,I.C., Hsueh,B.Y., Guzman,J., Waters,C.M., Zamorano-Sanchez,D., Espin,G, Nunez,C.. Increased c-di-GMP Levels Lead to the Production of Alginates of High Molecular Mass in Azotobacter vinelandii. Journal of Bacteriology, 202 (24), e00135-20, e00134-20.

Artículo

34 - Martinez-Ortiz,I.C., Ahumada-Manuel,C.L., Hsueh,B.Y., Guzman,J., Moreno,S., Cocotl-Yanez,M., Waters,C.M., Zamorano-Sanchez,D., Espin,G., Nunez,C. Cyclic di-GMP-Mediated Regulation of Extracellular Mannuronan C-5 Epimerases Is Essential for Cyst Formation in Azotobacter vinelandii. Journal of Bacteriology, 202 (24), e00135-20.

2018

Artículo

35 - Adaya, L., Millan, M., Pena, C., Jendrossek, D., Espin, G., Tinoco-Valencia, R., Guzman, J., Pfeiffer, D., Segura, D.. Inactivation of an intracellular poly-3-hydroxybutyrate depolymerase of Azotobacter vinelandii allows to obtain a polymer of uniform high molecular mass. Applied Microbiology and Biotechnology, 102 (6), 2693-2707.

Artículo

36 - Martinez-Valenzuela,M., Guzman,J., Moreno,S., Ahumada-Manuel,C.L., Espin,G., Nunez,C.. Expression of the sRNAs CrcZ and CrcY modulate the strength of carbon catabolite repression under diazotrophic or non-diazotrophic growing conditions in Azotobacter vinelandii. PLoS ONE, 13 (12), e0208975.

Artículo

37 - Rosas-Galvan, N.S., Martinez-Morales, F., Marquina-Bahena, S., Tinoco-Valencia, R., Serrano-Carreon, L., Bertrand, B., Leon-Rodriguez, R., Guzman-Aparicio, J., ALvarez-Berber, L., Trejo-Hernandez, M.D.R.. Improved production, purification and characterization of biosurfactants produced by Serratia marcescens SM3 and its isogenic SMRG-5 strain. Biotechnology and Applied Biochemistry, 65 (5), 690-700.

2017

Artículo

38 - Ahumada-Manuel, C.L., Guzman, J., Pena, C., Quiroz-Rocha, E., Espin, G., Nunez, C.. The signaling protein MucG negatively affects the production and the molecular mass of alginate in Azotobacter vinelandii. Applied Microbiology and Biotechnology, 101 (4), 1521-1534.

Artículo

39 - Quiroz-Rocha, E., Bonilla-Badia, F., Garcia-Aguilar, V., Lopez-Pliego, L., Serrano-Roman, J., Cocotl-Yanez, M., Guzman, J., Ahumada-Manuel, C.L., Muriel-Millan, L.F., Castaneda, M., Espin, G., Nunez, C.. Two-component system CbrA/CbrB controls alginate production in Azotobacter vinelandii. Microbiology, 163 (7), 1105-1115.

Artículo

40 - Quiroz-Rocha, E., Moreno, R., Hernandez-Ortiz, A., Fragoso-Jimenez, J.C., Muriel-Millan, L.F., Guzman, J., Espin, G., Rojo, F., Nunez, C.. Glucose uptake in Azotobacter vinelandii occurs through a GluP transporter that is under the control of the CbrA/CbrB and Hfq-Crc systems. Scientific Reports, 7 (1), 858.

2016

Artículo

41 - Romero,Y., Guzman,J., Moreno,S., Cocotl-Yanez,M., Vences-Guzman,M.A., Castaneda,M., Espin,G., Segura,D.. The GacS/A-RsmA Signal Transduction Pathway Controls the Synthesis of Alkylresorcinol Lipids that Replace Membrane Phospholipids during Encystment of Azotobacter vinelandii SW136. PLoS ONE, 11 (4), e0153266.

2013

Artículo

42 - Nunez,C., Pena,C., Kloeckner,W., Hernandez-Eligio,A., Bogachev,A.V., Moreno,S., Guzman,J., Buchs,J., Espin,G.. Alginate synthesis in Azotobacter vinelandii is increased by reducing the intracellular production of ubiquinone. Applied Microbiology and Biotechnology, 97 (6), 2503-2512.

Artículo

43 - Romero,Y., Moreno,S., Guzman,J., Espin,G., Segura,D.. The Sigma Factor RpoS Controls Alkylresorcinol Synthesis Through ArpR, a LysR-Type Regulatory Protein During Encystment of Azotobacter vinelandii. Journal of Bacteriology, 195 (8), 1834-1844.

2009

Artículo

44 - Nunez,C., Bogachev,A.V., Guzman,G., Tello,I., Guzman,J., Espin,G.. The Na+-translocating NADH : ubiquinone oxidoreductase of Azotobacter vinelandii negatively regulates alginate synthesis. Microbiology, 155 (Pt 1), 249-256.

2004

Artículo

45 - Gaona,G., Nunez,C., Goldberg,J.B., Linford,A.S., Najera,R., Castaneda,M., Guzman,J., Espin,G., Soberon-Chavez,G.. Characterization of the Azotobacter vinelandii algC gene involved in alginate and lipopolysaccharide production. Fems Microbiology Letters, 238 (1), 199-206.

2003

Artículo

46 - Segura,D., Guzman,J., Espin,G.. Azotobacter vinelandii mutants that overproduce poly-beta-hydroxybutyrate or alginate. Applied Microbiology and Biotechnology, 63 (2), 159-163.

2002

Artículo

47 - Peralta-Gil,M., Segura,D., Guzman,J., Servin-Gonzalez,L., Espin,G.. Expression of the Azotobacter vinelandii Poly-beta-Hydroxybutyrate Biosynthetic phbBAC Operon Is Driven by Two Overlapping Promoters and Is Dependent on the Transcriptional Activator PhbR. Journal of Bacteriology, 184 (20), 5672-5677.

2001

Artículo

48 - Gama-Castro,S., Nunez,C., Segura,D., Moreno,S., Guzman,J., Espin,G.. Azotobacter vinelandii Aldehyde Dehydrogenase Regulated by sigma(54): Role in Alcohol Catabolism and Encystment. Journal of Bacteriology, 183 (21), 6169-6174.

2000

Artículo

49 - Castaneda,M., Guzman,J., Moreno,S., Espin,G.. The GacS sensor kinase regulates alginate and poly-beta-hydroxybutyrate production in Azotobacter vinelandii. Journal of Bacteriology, 182 (9), 2624-2628.

Artículo

50 - Nunez,C., Leon,R., Guzman,J., Espin,G., Soberon-Chavez,G.. Role of Azotobacter vinelandii mucA and mucC gene products in alginate production. Journal of Bacteriology, 182 (23), 6550-6556.

1999

Artículo

51 - Vazquez,A., Moreno,S., Guzman,J., Alvarado,A., Espin,G.. Transcriptional organization of the Azotobacter vinelandii algGXLVIFA genes: characterization of algF mutants. Gene, 232 (2), 217-222.

1998

Artículo

52 - Moreno,S., Najera,R., Guzman,J., Soberon-Chavez,G., Espin,G.. Role of alternative sigma factor algU in encystment of Azotobacter vinelandii. Journal of Bacteriology, 180 (10), 2766-2769.

1997

Artículo

53 - Caba,J.M., Guzman,J., Ortega,J.L., Lluch,C., Lara,M., Ligero,F.. Purification and partial characterization of glutamine synthetase from root nodules of faba bean. Ars Pharmaceutica, 38 (4), 345-356.

Artículo

54 - Martinez,P., Guzman,J., Espin,G.. A mutation impairing alginate production increased accumulation of poly-beta-hydroxybutyrate in Azotobacter vinelandii. Biotechnology Letters, 19 (9), 909-911.

Artículo

55 - Mejia-Ruiz,H., Moreno,S., Guzman,J., Najera,R., Leon,R., Soberon-Chavez,G., Espin,G.. Isolation and characterization of an Azotobacter vinelandii algK mutant. Fems Microbiology Letters, 156 (1), 101-106.

Artículo

56 - Mejia-Ruiz,H., Guzman,J., Moreno,S., Soberon-Chavez,G., Espin,G.. The Azotobacter vinelandii alg8 and alg44 genes are essential for alginate synthesis and can be transcribed from an algD-independent promoter. Gene, 199 (1-2), 271-277.

1994

Revisión

57 - Espin,G., Moreno,S., Guzman,J.. Molecular genetics of the glutamine synthetases in Rhizobium species. Critical Reviews in Microbiology, 20 (2), 117-123.

Note

58 - Noguez,R., Moreno,S., Guzman,J., Espin,G.. The effect of the nitrogen and ntrC on the adenylylation of glutamine synthetase I in Rhizobium etli. Canadian Journal of Microbiology, 40 (11), 965-968.

1993

59 - Guzman Aparicio, Josefina. Rhizobium leguminosarum biovar phaseoli una bacteria simbiotica o patogena, una mutacion en glnT hace la diferencia . Facultad de Quimica, Maestro en Ciencias Quimicas (Bioquimica), UNAM. *

Asesor: Espin Ocampo, Elda Guadalupe

1991

Note

60 - Moreno,S., Meza,R., Guzman,J., Carabez,A., Espin,G.. The glnA Gene of Rhizobium leguminosarum bv. phaseoli and Its Role In Symbiosis. Molecular Plant-Microbe Interactions, 4 (6), 619-622.

1980

Note

61 - Sanchez,F., Calva,E., Campomanes,M., Blanco,L., Guzman,J., Saborio,J.L., Palacios,R.. Heterogeneity of glutamine synthetase polypeptides in Neurospora crassa. Journal of Biological Chemistry, 255 (6), 2231-2234. *

Internacional

62 - Mora,J., Davila,G., Espin,G., Gonzalez,A., Guzman,J., Hernandez.G., Hummelt,G., Lara,M., Martinez,E., Mora,Y., Romero,D.. Glutamine Metabolism in Neurospora crassa. Glutamine: Metabolism, Enzymology, and Regulation. 185-211. *

josefina.guzman@ibt.unam.mx

Grupo de la Dra. Guadalupe Espin