Dra. Constance Genevieve Jeanne Henriette Auvynet
Investigadora Titular A Tiempo Completo
Pequeños péptidos de defensa e inflamación
Número de registros: 3
- Activos
- Vencidos
- Identificación y caracterización de péptidos antimicrobianos con actividad antiinflamatoria derivados de la piel de ambystoma mexicanum, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2024 - 2025
- Caracterización del mecanismo de inducción de muerte bacteriana y de células inmunes por un péptido de defensa aislado de la rana mexicana pachymedusa dacnicolor, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2022 - 2023
- Pequeños péptidos antiinflamatorios y antimicrobianos aislados de la rana mexicana pachymedusa dacnicolor en el tratamiento de enfermedades inflamatorias, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2020 - 2021
Nivel I del SNII
Doctorado, Doctorado
- Activos
-
Maestría
Total de publicaciones: 25
- Tipo
- Fecha
Artículo
1 - Lacombe,C., Aleman-Navarro,E., Drujon,T., Martinez-Osorio,V., Sachon,E., Melchy-Perez,E., Carlier,L., Fajardo-Brigido,E., Fleury,Y., Piesse,C., Gutierrez-Escobedo,G., de las Penas,A., Castano,I., Desriac,A., Beristain-Hernandez,J.L., Combadiere,C., Rosenstein,Y., Auvynet,C. (2024). Characterization of a New Immunosuppressive and Antimicrobial Peptide, DRS-DA2, Isolated from the Mexican Frog, Pachymedusa dacnicolor.
International Journal of Inflammation,
2024.
Artículo
2 - Sandoval-Hernandez,M.A., Fierro,N.A., Veytia-Bucheli,J.I., Alvarado-Velazquez,D.A., Aleman-Navarro,E., Melchy-Perez,E., Auvynet,C., Imaz-Rosshandler,I., Carneiro,J., Perez-Rueda,E., Rosenstein,Y. (2024). Differential Impact of CD43 and CD28 on T-Cell Differentiation Depending on the Order of Engagement with the TCR.
International Journal of Molecular Sciences,
25 (6),
3135.
Articulo
3 - Gallegos-Monterrosa,R., Nunez,Y., Auvynet,C., Kumar,K.M., Tang,B., Ruiz-Ortega,L.I., Bustamante,V.H. (2023). Antibacterial and antibiofilm activities of ZIF-67.
Journal of Antibiotics,
76,
603?612.
Artículo
4 - Vega-Mendoza,D., Canas-Linares,A., Flores-Alcantar,A., Espinosa-Neira,R., Melchy-Perez,E., Vera-Estrella,R., Auvynet,C., Rosenstein,Y. (2021). CD43 (sialophorin) is involved in the induction of extracellular matrix remodeling and angiogenesis by lung cancer cells.
Journal of Cellular Physiology,
236 (9),
6643-6656.
Artículo
5 - Cardon,S., Sachon,E., Carlier,L., Drujon,T., Walrant,A., Aleman-Navarro,E., Martinez-Osorio,V., Guianvarc'h,D., Sagan,S., Fleury,Y., Marquant,R., Piesse,C., Rosenstein,Y., Auvynet,C., Lacombe,C. (2018). Peptidoglycan potentiates the membrane disrupting effect of the carboxyamidated form of DMS-DA6, a Gram-positive selective antimicrobial peptide isolated from Pachymedusa dacnicolor skin.
PLoS ONE,
13 (10),
e0205727.
Artículo
6 - Krishnan,M.L., Van Steenwinckel,J., Schang,A.L., Yan,J., Arnadottir,J., Le Charpentier,T., Csaba,Z., Dournaud,P., Cipriani,S., Auvynet,C., Titomanlio,L., Pansiot,J., Ball,G., Boardman,J.P., Walley,A.J., Saxena,A., Mirza,G., Fleiss,B., Edwards,A.D., Petretto,E., Gressens,P. (2017). Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infant.
Nature Communications,
8 (1).
*
Artículo
7 - Auvynet,C., Baudesson De Chanville,C., Hermand,P., Dorgham,K., Piesse,C., Pouchy,C., Carlier,L., Poupel,L., Barthelemy,S., Felouzis,V., Lacombe,C., Sagan,S., Salomon,B., Deterre,P., Sennlaub,F., Combadiere,C. (2016). ECL1i, d(LGTFLKC), a novel, small peptide that specifically inhibits CCL2-dependent migration.
FASEB Journal,
30 (6),
2370-2381.
*
Artículo
8 - Lacombe,C., Piesse,C., Sagan,S., Combadiere,C., Rosenstein,Y., Auvynet,C. (2015). Pachymodulin, a new functional formyl peptide receptor 2 (FPR2) peptidic ligand isolated from frog skin, has Janus-like immunomodulatory capacities.
Journal of Medicinal Chemistry,
58 (3),
1089-1099.
Artículo
9 - Van Steenwinckel,J., Auvynet,C., Sapienza,A., Reaux-Le Goazigo,A., Combadiere,C., Melik Parsadaniantz,S. (2015). Stromal cell-derived CCL2 drives neuropathic pain states through myeloid cell infiltration in injured nerve.
Brain, Behavior, and Immunity,
45,
198-210.
*
Artículo
10 - Auvynet,C., Moreno,S., Melchy,E., Coronado-Martinez,I., Montiel,J.L., Aguilar-Delfin,I., Rosenstein,Y. (2013). Galectin-1 promotes human neutrophil migration.
Glycobiology,
23 (1),
32-42.
Artículo
11 - Poupel,L., Boissonnas,A., Hermand,P., Dorgham,K., Guyon,E., Auvynet,C., Charles,F.S., Lesnik,P., Deterre,P., Combadiere,C. (2013). Pharmacological inhibition of the chemokine receptor, CX3CR1, reduces atherosclerosis in mice.
Arteriosclerosis, Thrombosis, and Vascular Biology,
33 (10),
2297-2305.
*
Artículo
12 - Rodero,M.P., Auvynet,C., Poupel,L., Combadiere,B., Combadiere,C. (2013). Control of both myeloid cell infiltration and angiogenesis by ccr1 promotes liver cancer metastasis development in mice.
Neoplasia,
15 (6),
641-648.
*
Artículo
13 - Sennlaub,F., Auvynet,C., Calippe,B., Lavalette,S., Poupel,L., Hu,S.J., Dominguez,E., Camelo,S., Levy,O., Guyon,E., Saederup,N., Charo,I.F., Rooijen,N.V., Nandrot,E., Bourges,J., Behar-Cohen,F., Sahel,J.A., Guillonneau,X., Raoul,W., Combadiere,C. (2013). CCR2 + monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice.
EMBO Molecular Medicine,
5 (11),
1775-1793.
*
Artículo
14 - Cochain,C., Auvynet,C., Poupel,L., Vilar,J., Dumeau,E., Richart,A., Zouggari,Y., Yin,K.Y.H.W., Bruneval,P., Renault,G., Marchiol,C., Bonnin,P., Bonecchi,R., Locati,M., Silvestre,J.S. (2012). The chemokine decoy receptor D6 prevents excessive inflammation and adverse ventricular remodeling after myocardial infarction.
Arteriosclerosis, Thrombosis, and Vascular Biology,
32 (9),
2206-2213.
*
Artículo
15 - Ramos,M.V., Auvynet,C., Poupel,L., Rodero,M., Mejias,M.P., Panek,C.A., Vanzulli,S., Combadiere,C., Palermo,M. (2012). Chemokine receptor CCR1 disruption limits renal damage in a murine model of hemolytic uremic syndrome.
American Journal of Pathology,
180 (3),
1040-1048.
*
Revisión
16 - Raoul,W., Lelievre,E., Auvynet,C., Feumi,C., Combadiere,C., Sennlaub,F. (2010). Role of chemokines in the development of age-related macular degeneration.
Biologie Aujourd'hui,
204 (4),
311-319.
*
Revisión
17 - Raoul,W., Auvynet,C., Camelo,S., Guillonneau,X., Feumi,C., Combadiere,C., Sennlaub,F. (2010). CCL2/CCR2 and CX3CL1/CX3CR1 chemokine axes and their possible involvement in age-related macular degeneration.
Journal of Neuroinflammation,
7.
*
Artículo
18 - Auvynet,C., Joanne,P., Bourdais,J., Nicolas,P., Lacombe,C., Rosenstein,Y. (2009). Dermaseptin DA4, although closely related to dermaseptin B2, presents chemotactic and Gram-negative selective bactericidal activities.
Febs Journal,
272 (22),
6773-6786.
Revisión
19 - Auvynet,C., Rosenstein,Y. (2009). Multifunctional host defense peptides: Antimicrobial peptides, the small yet big players in innate and adaptive immunity.
Febs Journal,
276 (22),
6497-6508.
Artículo
20 - Auvynet,C., Topalis,D., Caillat,C., Munier-Lehmann,H., Seclaman,E., Balzarini,J., Agrofoglio,L.A., Kaminski,P.A., Meyer,P., Deville-Bonne,D., El Amri,C. (2009). Phosphorylation of dGMP analogs by vaccinia virus TMP kinase and human GMP kinase.
Biochemical and Biophysical Research Communications,
388 (1),
6-11.
*
Artículo
21 - Joanne,P., Falord,M., Chesneau,O., Lacombe,C., Castano,S., Desbat,B., Auvynet,C., Nicolas,P., Msadek,T., El-Amri,C. (2009). Comparative study of two plasticins: specificity, interfacial behavior, and bactericidal activity.
Biochemistry,
48 (40),
9372-9383.
Artículo
22 - Auvynet,C., El-Amri,C., Lacombe,C., Bruston,F., Bourdais,J., Nicolas,P., Rosenstein,Y. (2008). Structural requirements for antimicrobial versus chemoattractant activities for dermaseptin S9.
Febs Journal,
275 (16),
4134-4151.
Artículo
23 - Auvynet,C., Seddiki,N., Dunia,I., Nicolas,P., Amiche,M., Lacombe,C. (2006). Post-translational amino acid racemization in the frog skin peptide deltorphin I in the secretion granules of cutaneous serous glands.
European Journal of Cell Biology,
85 (1),
25-34.
*
Editorial material
24 - Chemtob,S., Rosenstein,Y., Auvynet,C. (2022). Editorial: Use of small peptides in the treatment of inflammatory diseases.
Frontiers in Pharmacology,
13,
1090014.
Nacional divulgacion
25 - Rosenstein,Y., Auvynet,C. (2022). Las ranas: de la medicina tradicional a nuevos fármacos.
Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM,
31 (Octubre-Diciembre).
Artículo
26 - Lacombe,C., Aleman-Navarro,E., Drujon,T., Martinez-Osorio,V., Sachon,E., Melchy-Perez,E., Carlier,L., Fajardo-Brigido,E., Fleury,Y., Piesse,C., Gutierrez-Escobedo,G., de las Penas,A., Castano,I., Desriac,A., Beristain-Hernandez,J.L., Combadiere,C., Rosenstein,Y., Auvynet,C.. Characterization of a New Immunosuppressive and Antimicrobial Peptide, DRS-DA2, Isolated from the Mexican Frog, Pachymedusa dacnicolor.
International Journal of Inflammation,
2024.
Artículo
27 - Sandoval-Hernandez,M.A., Fierro,N.A., Veytia-Bucheli,J.I., Alvarado-Velazquez,D.A., Aleman-Navarro,E., Melchy-Perez,E., Auvynet,C., Imaz-Rosshandler,I., Carneiro,J., Perez-Rueda,E., Rosenstein,Y.. Differential Impact of CD43 and CD28 on T-Cell Differentiation Depending on the Order of Engagement with the TCR.
International Journal of Molecular Sciences,
25 (6),
3135.
Articulo
28 - Gallegos-Monterrosa,R., Nunez,Y., Auvynet,C., Kumar,K.M., Tang,B., Ruiz-Ortega,L.I., Bustamante,V.H.. Antibacterial and antibiofilm activities of ZIF-67.
Journal of Antibiotics,
76,
603?612.
Editorial material
29 - Chemtob,S., Rosenstein,Y., Auvynet,C.. Editorial: Use of small peptides in the treatment of inflammatory diseases.
Frontiers in Pharmacology,
13,
1090014.
Nacional divulgacion
30 - Rosenstein,Y., Auvynet,C.. Las ranas: de la medicina tradicional a nuevos fármacos.
Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM,
31 (Octubre-Diciembre).
Artículo
31 - Vega-Mendoza,D., Canas-Linares,A., Flores-Alcantar,A., Espinosa-Neira,R., Melchy-Perez,E., Vera-Estrella,R., Auvynet,C., Rosenstein,Y.. CD43 (sialophorin) is involved in the induction of extracellular matrix remodeling and angiogenesis by lung cancer cells.
Journal of Cellular Physiology,
236 (9),
6643-6656.
Artículo
32 - Cardon,S., Sachon,E., Carlier,L., Drujon,T., Walrant,A., Aleman-Navarro,E., Martinez-Osorio,V., Guianvarc'h,D., Sagan,S., Fleury,Y., Marquant,R., Piesse,C., Rosenstein,Y., Auvynet,C., Lacombe,C.. Peptidoglycan potentiates the membrane disrupting effect of the carboxyamidated form of DMS-DA6, a Gram-positive selective antimicrobial peptide isolated from Pachymedusa dacnicolor skin.
PLoS ONE,
13 (10),
e0205727.
Artículo
33 - Krishnan,M.L., Van Steenwinckel,J., Schang,A.L., Yan,J., Arnadottir,J., Le Charpentier,T., Csaba,Z., Dournaud,P., Cipriani,S., Auvynet,C., Titomanlio,L., Pansiot,J., Ball,G., Boardman,J.P., Walley,A.J., Saxena,A., Mirza,G., Fleiss,B., Edwards,A.D., Petretto,E., Gressens,P.. Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infant.
Nature Communications,
8 (1).
*
Artículo
34 - Auvynet,C., Baudesson De Chanville,C., Hermand,P., Dorgham,K., Piesse,C., Pouchy,C., Carlier,L., Poupel,L., Barthelemy,S., Felouzis,V., Lacombe,C., Sagan,S., Salomon,B., Deterre,P., Sennlaub,F., Combadiere,C.. ECL1i, d(LGTFLKC), a novel, small peptide that specifically inhibits CCL2-dependent migration.
FASEB Journal,
30 (6),
2370-2381.
*
Artículo
35 - Lacombe,C., Piesse,C., Sagan,S., Combadiere,C., Rosenstein,Y., Auvynet,C.. Pachymodulin, a new functional formyl peptide receptor 2 (FPR2) peptidic ligand isolated from frog skin, has Janus-like immunomodulatory capacities.
Journal of Medicinal Chemistry,
58 (3),
1089-1099.
Artículo
36 - Van Steenwinckel,J., Auvynet,C., Sapienza,A., Reaux-Le Goazigo,A., Combadiere,C., Melik Parsadaniantz,S.. Stromal cell-derived CCL2 drives neuropathic pain states through myeloid cell infiltration in injured nerve.
Brain, Behavior, and Immunity,
45,
198-210.
*
Artículo
37 - Auvynet,C., Moreno,S., Melchy,E., Coronado-Martinez,I., Montiel,J.L., Aguilar-Delfin,I., Rosenstein,Y.. Galectin-1 promotes human neutrophil migration.
Glycobiology,
23 (1),
32-42.
Artículo
38 - Poupel,L., Boissonnas,A., Hermand,P., Dorgham,K., Guyon,E., Auvynet,C., Charles,F.S., Lesnik,P., Deterre,P., Combadiere,C.. Pharmacological inhibition of the chemokine receptor, CX3CR1, reduces atherosclerosis in mice.
Arteriosclerosis, Thrombosis, and Vascular Biology,
33 (10),
2297-2305.
*
Artículo
39 - Rodero,M.P., Auvynet,C., Poupel,L., Combadiere,B., Combadiere,C.. Control of both myeloid cell infiltration and angiogenesis by ccr1 promotes liver cancer metastasis development in mice.
Neoplasia,
15 (6),
641-648.
*
Artículo
40 - Sennlaub,F., Auvynet,C., Calippe,B., Lavalette,S., Poupel,L., Hu,S.J., Dominguez,E., Camelo,S., Levy,O., Guyon,E., Saederup,N., Charo,I.F., Rooijen,N.V., Nandrot,E., Bourges,J., Behar-Cohen,F., Sahel,J.A., Guillonneau,X., Raoul,W., Combadiere,C.. CCR2 + monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice.
EMBO Molecular Medicine,
5 (11),
1775-1793.
*
Artículo
41 - Cochain,C., Auvynet,C., Poupel,L., Vilar,J., Dumeau,E., Richart,A., Zouggari,Y., Yin,K.Y.H.W., Bruneval,P., Renault,G., Marchiol,C., Bonnin,P., Bonecchi,R., Locati,M., Silvestre,J.S.. The chemokine decoy receptor D6 prevents excessive inflammation and adverse ventricular remodeling after myocardial infarction.
Arteriosclerosis, Thrombosis, and Vascular Biology,
32 (9),
2206-2213.
*
Artículo
42 - Ramos,M.V., Auvynet,C., Poupel,L., Rodero,M., Mejias,M.P., Panek,C.A., Vanzulli,S., Combadiere,C., Palermo,M.. Chemokine receptor CCR1 disruption limits renal damage in a murine model of hemolytic uremic syndrome.
American Journal of Pathology,
180 (3),
1040-1048.
*
Revisión
43 - Raoul,W., Lelievre,E., Auvynet,C., Feumi,C., Combadiere,C., Sennlaub,F.. Role of chemokines in the development of age-related macular degeneration.
Biologie Aujourd'hui,
204 (4),
311-319.
*
Revisión
44 - Raoul,W., Auvynet,C., Camelo,S., Guillonneau,X., Feumi,C., Combadiere,C., Sennlaub,F.. CCL2/CCR2 and CX3CL1/CX3CR1 chemokine axes and their possible involvement in age-related macular degeneration.
Journal of Neuroinflammation,
7.
*
Artículo
45 - Auvynet,C., Joanne,P., Bourdais,J., Nicolas,P., Lacombe,C., Rosenstein,Y.. Dermaseptin DA4, although closely related to dermaseptin B2, presents chemotactic and Gram-negative selective bactericidal activities.
Febs Journal,
272 (22),
6773-6786.
Revisión
46 - Auvynet,C., Rosenstein,Y.. Multifunctional host defense peptides: Antimicrobial peptides, the small yet big players in innate and adaptive immunity.
Febs Journal,
276 (22),
6497-6508.
Artículo
47 - Auvynet,C., Topalis,D., Caillat,C., Munier-Lehmann,H., Seclaman,E., Balzarini,J., Agrofoglio,L.A., Kaminski,P.A., Meyer,P., Deville-Bonne,D., El Amri,C.. Phosphorylation of dGMP analogs by vaccinia virus TMP kinase and human GMP kinase.
Biochemical and Biophysical Research Communications,
388 (1),
6-11.
*
Artículo
48 - Joanne,P., Falord,M., Chesneau,O., Lacombe,C., Castano,S., Desbat,B., Auvynet,C., Nicolas,P., Msadek,T., El-Amri,C.. Comparative study of two plasticins: specificity, interfacial behavior, and bactericidal activity.
Biochemistry,
48 (40),
9372-9383.
Artículo
49 - Auvynet,C., El-Amri,C., Lacombe,C., Bruston,F., Bourdais,J., Nicolas,P., Rosenstein,Y.. Structural requirements for antimicrobial versus chemoattractant activities for dermaseptin S9.
Febs Journal,
275 (16),
4134-4151.
Artículo
50 - Auvynet,C., Seddiki,N., Dunia,I., Nicolas,P., Amiche,M., Lacombe,C.. Post-translational amino acid racemization in the frog skin peptide deltorphin I in the secretion granules of cutaneous serous glands.
European Journal of Cell Biology,
85 (1),
25-34.
*