Dra. Hilda Vazquez Lopez
Investigador Posdoctoral por Proyecto
Biología Molecular y Bioquímica de venenos de animales ponzoñosos
Doctorado, Doctor
- Graduados
1 - López Galindo, Diana Alexis (2019). Evaluación del plásmido de expresión intracelular ppic3.5 en la producción del anticuerpo scfv 6009f en pichia pastoris gs115 y km71.
Centro de Investigación en Biotecnología,
Maestría en Biotecnologia,
UAEM.
*
Asesor: Villagas Villarreal,Elba Cristina, Vázquez López, Hilda
Total de publicaciones: 15
- Tipo
- Fecha
Artículo
2 - Adame,M., Vazquez,H., Juarez-Lopez,D., Corzo,G., Amezcua,M., Lopez,D., Gonzalez,Z., Schcolnik-Cabrera,A., Morales-Martinez,A., Villegas,E. (2024). Expression and characterization of scFv-6009FV in Pichia pastoris with improved ability to neutralize the neurotoxin Cn2 from Centruroides noxius.
International Journal of Biological Macromolecules,
275 (1),
133461.
Artículo
3 - Olivares-Hernandez,R., Riano-Umbarila,L., Becerril,B., Alagon-Cano,A., Vazquez-Lopez,H. (2024). Pharmacokinetic evaluation of a single chain antibody fragment against scorpion toxins in sheep.
Toxicon,
242,
107691.
Artículo
4 - Siegrist,A.A., Boyer,L., Balchan,N.R., Vazquez,H., Alagon,A., de Roodt,A., Craig,I.S., Poulin,I.S., Timmerman,A., Trocola,D. (2023). Outcomes of treatment of snake and scorpion envenomation in birds of prey, with and without antivenom.
Journal of Zoo and Wildlife Medicine,
53 (4),
870-881.
Artículo
5 - Roman-Dominguez,L., Neri-Castro,E., Vazquez-Lopez,H., Garcia-Osorio,B., Archundia,I.G., Ortiz-Medina,J.A., Petricevich,V.L., Alagon,A., Benard-Valle,M. (2019). Biochemical and immunochemical characterization of venoms from snakes of the genus Agkistrodon.
Toxicon X,
4,
100013.
Artículo
6 - Diaz,P., Malave,C., Zerpa,N., Vazquez,H., D'Suze,G., Montero,Y., Castillo,C., Alagon,A., Sevcik,C. (2014). IgY pharmacokinetics in rabbits: Implications for IgY use as antivenoms.
Toxicon,
90,
124-133.
Artículo
7 - Sevcik,C., Salazar,V., Diaz,P., D'Suze,G., Vazquez,H. (2013). High resolution fluorescence microscopy evidence on the transport of immunoglobulins. Differences between mammalian IgG, F(ab')2 and avian IgY.
Toxicon,
63,
7-18.
*
Artículo
8 - Vazquez,H., Olvera,F., Alagon,A., Sevcik,C. (2013). Production of anti-horse antibodies induced by IgG, F(ab') and Fab applied repeatedly to rabbits. Effect on antivenom pharmacokinetics.
Toxicon,
76,
362-369.
Artículo
9 - Sevcik,C., D'Suze,G., Salazar,V., Diaz,P., Vazquez,H. (2012). Horse IgG- and ostrich IgY-F(ab')(2) groups have different affinities for mice erythrocytes and lymphocytes. Implications for avian immunoglobulin therapeutic usefulness.
Toxicon,
60 (6),
1215-1221.
*
Artículo
10 - Vazquez,H., Chavez-Haro,A., Garcia-Ubbelohde,W., Paniagua-Solis,J., Alagon,A., Sevcik,C. (2010). Pharmacokinetics of a F(ab')(2) scorpion antivenom administered intramuscularly in healthy human volunteers.
International Immunopharmacology,
10 (11),
1318-1324.
Artículo
11 - Vazquez,H., Olvera,F., Paniagua-Solis,J., Alagon,A., Sevcik,C. (2010). Pharmacokinetics in rabbits and anti-sphingomyelinase D neutralizing power of Fab, F(ab')2, IgG and IgG(T) fragments from hyper immune equine plasma.
International Immunopharmacology,
10 (4),
447-454.
Artículo
12 - Chase,P., Boyer-Hassen,L., McNally,J., Vazquez,H.L., Theodorou,A.A., Walter,F.G., Alagon,A. (2009). Serum levels and urine detection of Centruroides sculpturatus venom in significantly envenomated patients.
Clinical Toxicology,
47 (1),
24-28.
Carta
13 - Dragulev,B., Bao,Y., Ramos-Cerrillo,B., Vazquez,H., Olvera,A., Stock,R., Algaron,A., Fox,J.W. (2007). Upregulation of IL-6, IL-8, CXCL1, and CXCL2 Dominates Gene Expression in Human Fibroblast Cells Exposed to Loxosceles reclusa Sphingomyelinase D: Insights into Spider Venom Dermonecrosis.
Journal of Investigative Dermatology,
127 (5),
1264-1266.
Carta
14 - Dragulev,B., Bao,Y., Ramos-Cerrillo,B., Vazquez,H., Olvera,A., Stock,R.P., Alagon,A., Fox,J.W. (2007). Upregulation of cytokine expression in fibroblasts exposed to Loxosceles sphingomyelinase D: What is the trigger? - Response to Moolenaar et al.
Journal of Investigative Dermatology,
127 (5),
1267-1268.
Artículo
15 - Olvera,A., Ramos-Cerrillo,B., Estevez,J., Clement,H., de Roodt,A., Paniagua-Solis,J., Vazquez,H., Zavaleta,A., Salas-Arruz,M., Stock,R.P., Alagon,A. (2006). North and South American Loxosceles spiders: Development of a polyvalent antivenom with recombinant sphingomyelinases D as antigens.
Toxicon,
48 (1),
64-74.
Artículo
16 - Vazquez,H., Chavez-Haro,A., Garcia-Ubbelohde,W., Mancilla-Nava,R., Paniagua-Solis,J., Alagon,A., Sevcik,C. (2005). Pharmacokinetics of a F(ab')(2) scorpion antivenom in healthy human volunteers.
Toxicon,
46 (7),
797-805.
Artículo
17 - Adame,M., Vazquez,H., Juarez-Lopez,D., Corzo,G., Amezcua,M., Lopez,D., Gonzalez,Z., Schcolnik-Cabrera,A., Morales-Martinez,A., Villegas,E.. Expression and characterization of scFv-6009FV in Pichia pastoris with improved ability to neutralize the neurotoxin Cn2 from Centruroides noxius.
International Journal of Biological Macromolecules,
275 (1),
133461.
Artículo
18 - Olivares-Hernandez,R., Riano-Umbarila,L., Becerril,B., Alagon-Cano,A., Vazquez-Lopez,H.. Pharmacokinetic evaluation of a single chain antibody fragment against scorpion toxins in sheep.
Toxicon,
242,
107691.
Artículo
19 - Siegrist,A.A., Boyer,L., Balchan,N.R., Vazquez,H., Alagon,A., de Roodt,A., Craig,I.S., Poulin,I.S., Timmerman,A., Trocola,D.. Outcomes of treatment of snake and scorpion envenomation in birds of prey, with and without antivenom.
Journal of Zoo and Wildlife Medicine,
53 (4),
870-881.
Artículo
20 - Roman-Dominguez,L., Neri-Castro,E., Vazquez-Lopez,H., Garcia-Osorio,B., Archundia,I.G., Ortiz-Medina,J.A., Petricevich,V.L., Alagon,A., Benard-Valle,M.. Biochemical and immunochemical characterization of venoms from snakes of the genus Agkistrodon.
Toxicon X,
4,
100013.
Artículo
21 - Diaz,P., Malave,C., Zerpa,N., Vazquez,H., D'Suze,G., Montero,Y., Castillo,C., Alagon,A., Sevcik,C.. IgY pharmacokinetics in rabbits: Implications for IgY use as antivenoms.
Toxicon,
90,
124-133.
Artículo
22 - Sevcik,C., Salazar,V., Diaz,P., D'Suze,G., Vazquez,H.. High resolution fluorescence microscopy evidence on the transport of immunoglobulins. Differences between mammalian IgG, F(ab')2 and avian IgY.
Toxicon,
63,
7-18.
*
Artículo
23 - Vazquez,H., Olvera,F., Alagon,A., Sevcik,C.. Production of anti-horse antibodies induced by IgG, F(ab') and Fab applied repeatedly to rabbits. Effect on antivenom pharmacokinetics.
Toxicon,
76,
362-369.
Artículo
24 - Sevcik,C., D'Suze,G., Salazar,V., Diaz,P., Vazquez,H.. Horse IgG- and ostrich IgY-F(ab')(2) groups have different affinities for mice erythrocytes and lymphocytes. Implications for avian immunoglobulin therapeutic usefulness.
Toxicon,
60 (6),
1215-1221.
*
Artículo
25 - Vazquez,H., Chavez-Haro,A., Garcia-Ubbelohde,W., Paniagua-Solis,J., Alagon,A., Sevcik,C.. Pharmacokinetics of a F(ab')(2) scorpion antivenom administered intramuscularly in healthy human volunteers.
International Immunopharmacology,
10 (11),
1318-1324.
Artículo
26 - Vazquez,H., Olvera,F., Paniagua-Solis,J., Alagon,A., Sevcik,C.. Pharmacokinetics in rabbits and anti-sphingomyelinase D neutralizing power of Fab, F(ab')2, IgG and IgG(T) fragments from hyper immune equine plasma.
International Immunopharmacology,
10 (4),
447-454.
Artículo
27 - Chase,P., Boyer-Hassen,L., McNally,J., Vazquez,H.L., Theodorou,A.A., Walter,F.G., Alagon,A.. Serum levels and urine detection of Centruroides sculpturatus venom in significantly envenomated patients.
Clinical Toxicology,
47 (1),
24-28.
Carta
28 - Dragulev,B., Bao,Y., Ramos-Cerrillo,B., Vazquez,H., Olvera,A., Stock,R., Algaron,A., Fox,J.W.. Upregulation of IL-6, IL-8, CXCL1, and CXCL2 Dominates Gene Expression in Human Fibroblast Cells Exposed to Loxosceles reclusa Sphingomyelinase D: Insights into Spider Venom Dermonecrosis.
Journal of Investigative Dermatology,
127 (5),
1264-1266.
Carta
29 - Dragulev,B., Bao,Y., Ramos-Cerrillo,B., Vazquez,H., Olvera,A., Stock,R.P., Alagon,A., Fox,J.W.. Upregulation of cytokine expression in fibroblasts exposed to Loxosceles sphingomyelinase D: What is the trigger? - Response to Moolenaar et al.
Journal of Investigative Dermatology,
127 (5),
1267-1268.
Artículo
30 - Olvera,A., Ramos-Cerrillo,B., Estevez,J., Clement,H., de Roodt,A., Paniagua-Solis,J., Vazquez,H., Zavaleta,A., Salas-Arruz,M., Stock,R.P., Alagon,A.. North and South American Loxosceles spiders: Development of a polyvalent antivenom with recombinant sphingomyelinases D as antigens.
Toxicon,
48 (1),
64-74.
Artículo
31 - Vazquez,H., Chavez-Haro,A., Garcia-Ubbelohde,W., Mancilla-Nava,R., Paniagua-Solis,J., Alagon,A., Sevcik,C.. Pharmacokinetics of a F(ab')(2) scorpion antivenom in healthy human volunteers.
Toxicon,
46 (7),
797-805.