Dr. Guillermo Gosset Lagarda

Dr. Guillermo Gosset Lagarda
Investigador Titular C Tiempo Completo
Departamento de Ingeniería Celular y Biocatálisis

Líneas Investigación
Proyectos
Logros Obtenidos
Estudiantes
Publicaciones

Cerrar secciones Abrir secciones

Líneas Investigación

Ingeniería metabólica

Ingeniería y Tecnología de las Fermentaciones y del Cultivo Celular

Proyectos

Número de registros: 20

Activos
Vencidos

2025

Ingeniería metabólica y evolución adaptativa en laboratorio aplicadas a la generación y caracterización de cepas recombinantes de actinobacillus succinogenes para la producción de ácido succínico a partir de fuentes de carbono de bajo costo, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2025 - 2027

2022

Generación y caracterización de cepas recombinantes de actinobacillus succinogenes para la producción de ácido succínico a partir de residuos agroindustriales, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2022 - 2024

2019

Diseño de esquemas de control dinámico en cepas de escherichia coli para mejorar la producción de proteína recombinante, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2019 - 2022

2017

biosíntesis de ácido cafeico mediante ingeniería metabólica de escherichia coli, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2017 - 2020

2014

Análisis de flujos metabólicos en cepas de escherichia coli con modificaciones en sistemas de transporte de glucosa, COORDINACIÓN-INTERCAMBIO ACADÉMICO, 2014 - 2015
Fisiología microbiana e ingeniería de vías metabólicas, PRESUPUESTO UNAM, 2014 - 2020
Ingeniería del metabolismo central en escherichia coli para incrementar la disponibilidad del precursor malonil coenzima a y su aplicación a la producción de estilbenos, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2014 - 2016

2013

Estancia en la escuela de ingeniería química de la universidad de purdue, estados unidos, DIRECCIÓN GENERAL DE COOPERACIÓN E INTERNACIONALIZACIÓN, 2013
Análisis de flujos metabólicos en cepas de escherichia coli modificadas en la capacidad de transporte de glucosa, DEPARTAMENTO DE INTERCAMBIO ACADÉMICO/COORDINACIÓN DE LA INVESTIGACIÓN CIENTÍFICA-UNAM, 2013

2012

Biología sintética y bioprospección genómica de estilbenos para su producción mediante sistemas bacterianos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2012 - 2017
13c-flux analysis of escherichia coli strains modified by metabolic engineering for the production of aromatic compounds, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2012 - 2013

2011

Ingeniería de vías metabólicas en escherichia coli para la producción de compuestos derivados de l-tirosina, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2011 - 2012
Ingeniería metabólica para la producción de ácidos mandélicos con bacterias recombinantes, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2011 - 2012

2009

Ingeniería de enzimas del metabolismo central y de la síntesis de compuestos aromáticos y su aplicación a la ingeniería metabólica de escherichia coli, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2009 - 2012
Caracterización de cepas mutantes de bacillus subtilis que carecen del sistema de fosfotransferasa y su aplicación en procesos biotecnológicos, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2009 - 2010

2007

Generación enzimática de polímeros aromáticos y su caracterización fisicoquímica, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2007 - 2008
Desarrollo y caracterización de cepas de bacillus subtilis con modificaciones en el metabolismo central de carbono a nivel del nodo de fosfoenolpiruvato, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2007 - 2008

2006

Produccion de melanina mediante un proceso fermentativo., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2006 - 2007

2004

Caracterización del transcriptoma y la organización cromosomal en cepas de escherichia coli que carecen del sistema de fosfotransferasa, por medio de microarreglos de adn., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2004 - 2005
Caracterización del transcriptoma y la organización cromosomal en cepas de escherichia coli que carecen del sistema de fosfotransferasa por medio de microarreglos de adn., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2004 - 2005

Grado Académico

Doctorado, en Biotecnología, IBt-UNAM (1993)
Maestría, Investigacion Biomedica Basica, CEINGEBI-UNAM (1988)
Licenciatura, Biología, Escuela de Biología, Guadalajara

Estudiantes

Activos
Graduados

Doctorado

Mitzi de la Cruz Hernández
María de Lourdes Morales Corona
M. en C. José Ignacio Rodríguez Ochoa
M. C. Angélica Vallejo Giraldo
Caracterización del sistema de transporte de azúcares y el fenómeno de represión catabólica en Actinobacillus succinogenes.
M. C. Nadia Mariela Varela Pérez
Estudio del metabolismo de lactosa en Actinobacillus succinogenes 130Z y su aplicación para la producción de ácido succínico.

Maestría

Norman Franco Brito Robles
Estudio del efecto de la expresión recombinante de una tirosinasa en Escherichia coli sobre la resistencia a compuestos tóxicos en hidrolizados de residuos agroindustriales.
Jazmin Melendez Yahuitl
Ingeniería metabólica de Actinobacillus succinogenes para el metabolismo de sacarosa mediante un sistema alternativo al PTS.

Licenciatura

Oriana García Diez
Karyme Cristal Torres Rodríguez
Generación y caracterización de cepas de Escherichia coli para la producción de ácido 4-hidroxibenzoato

1 - Fragoso Jimenez, Juan Carlos (2023). Las implicaciones fisiologicas de la reduccion en la capacidad de consumo de glucosa en Escherichia coli y su aplicacion como estrategia para incrementar la produccion de proteina recombinante. Instituto de Biotecnologia, Doctorado en Bioquimicas.

Asesor: Gosset Lagarda, Guillermo

2 - Calzada Hernandez, Raul Alejandro (2023). Estudio del efecto de la inactivacion del sistema AaeXAB de Escherichia coli sobre la capacidad de sintesis de acido cafeico. Facultad de Ciencias, Licenciatura en Biologia, UNAM. *

Asesor: Gosset Lagarda, Guillermo

3 - Echanove Cuevas, Diego Alonso (2022). Revision de los factores SIGMA en Escherichia coli, su potencial como dianas para el mejoramiento de cepas de produccion de proteina recombinante, y una propuesta para su evaluacion experimental. Facultad de Ciencias, Licenciatura en Biologia, UNAM. *

Asesor: Gosset Lagarda, Guillermo

4 - Garcia Pinete, Emily (2021). Caracterizacion de mutantes en factores sigma de Escherichia coli. Facultad de Ciencias, Licenciatura en Biologia, UNAM. *

Asesor: Gosset Lagarda, Guillermo

5 - Rosas Rivera, Daniel Abner (2020). Efecto de la eliminacion de los genes pykA y pykF en la produccion de acido p-hidroxicinamico (pHCA), en cepas modificadas de Escherichia coli, utilizando glicerol como fuente de carbono . Instituto de Biotecnologia, Maestria en Ciencias Bioquimicas, UNAM.

Asesor: Gosset Lagarda, Guillermo

6 - Rodriguez Ochoa, Jose Ignacio (2020). Estudio transcriptomico de la cepa W3110 de Escherichia coli en presencia de acido cumarico. Instituto de Biotecnologia, Maestría en Ciencias Bioquímicas, UNAM.

Asesor: Gosset Lagarda, Guillermo

7 - Barrientos Paras, Jimena (2020). Producción de ácido caféico por un sistema de cocultivo de Escherichia coli . Facultad de Ciencias, Licenciatura en Biología, UNAM. *

Asesor: Gosset Lagarda, Guillermo

8 - Maldonado Carmona, Nidia (2018). Participacion del regulador de respuesta SCO2440 en el metabolismo de arabinosa en Streptomyces coelicolor . Instituto de Investigaciones Biomedicas, Maestria en Ciencias Bioquimicas,, UNAM. *

Asesor: Gosset Lagarda, Guillermo, Sanchez Esquivel, Sergio, Mejia Alvarez, Armando

9 - Salas Navarrete, Prisciluis Caheri (2017). Ingenieria metabolica para la produccion de pinosilvina en escherichia coli . Instituto de Biotecnologia, Maestria en Ciencias Bioquimicas, UNAM.

Asesor: Gosset Lagarda, Guillermo

10 - Camacho Zaragoza, Jose Manuel (2016). Ingenieria de vias metabolicas para la biosintesis de resveratrol en escherichia coli . Instituto de Biotecnologia, Maestria en Ciencias Bioquimicas, UNAM.

Asesor: Gosset Lagarda, Guillermo

11 - Vargas Tah, Ana Alejandra (2015). Produccion de acidos cinamico y phidroxicinamico en cepas de escherichia coli pts+ y ptsglc+, empleando azucares simples y una mezcla de estas . Instituto de Biotecnologia, Doctorado en Ciencias Bioquimicas, UNAM.

Asesor: Gosset Lagarda, Guillermo

12 - Mejia Caballero, Maria Alejandra (2015). Generacion y caracterizacion de versiones truncadas de la enzima tirosinasa melac de rhizobium etli expresada en escherichia coli . Instituto de Biotecnologia, Maestria en Ciencias Bioquimicas, UNAM.

Asesor: Gosset Lagarda, Guillermo

13 - Hernandez Navia, Sonia Elizabeth (2015). Ingenieria metabolica en escherichia coli para la conversion de glucosa en acido cumarico mediante la expresion del gene pal de rhodotorula glutinis que codifica para la enzima tirosina amonio liasa . Facultad de Ciencias, Licenciatura en Biologia, UNAM. *

Asesor: Gosset Lagarda, Guillermo

14 - Heres Rojas, Alan Enrique (2014). Caracterizacion de cepas derivadas de bacillus subtilis 168 pts obtenidas por evolucion adaptativa y modificadas para su uso en la produccion de lactato. Facultad de Ciencias, Licenciatura en Biologia, UNAM. *

Asesor: Gosset Lagarda, Guillermo

15 - Ferreira Gomez, David (2014). Generación y caracterización de una biblioteca de secuencias promotoras y sitios de unión a ribosoma en escherichia coli . Facultad de Ciencias, Licenciatura en Biología, UNAM. *

Asesor: Gosset Lagarda, Guillermo

16 - Carrasco Espinosa, Ingue Karen (2014). Efecto de la inactivacion del sistema de fosfotransferasa en bacillus subtilis sobre la capacidad de sintesis de la proteina verde fluorescente. Facultad de Ciencias, Licenciatura en Biologia, UNAM. *

Asesor: Gosset Lagarda, Guillermo

17 - Cabrera Valladares, Natividad (2014). Modificacion del metabolismo central de carbono en bacillus subtilis para la produccion de compuestos aromaticos . Instituto de Biotecnologia, Doctorado en Ciencias Bioquimicas, UNAM.

Asesor: Gosset Lagarda, Guillermo

18 - Meza Mora, Eugenio Arturo (2013). Estudio sobre el efecto de la actividad de piruvato cinasa en la distribucion de flujos en el metabolismo central de una cepa de Escherichia coli que carece del sistema de fosfotransferasa . Instituto de Biotecnologia, Doctorado en Ciencias Bioquimicas, UNAM.

Asesor: Gosset Lagarda, Guillermo

19 - Fuentes Ponce, Laura Grecia (2013). Generacion y caracterizacion de cepas de escherichia coli modificadas en la capacidad del transporte de glucosa . Instituto de Biotecnologia, Maestria en Ciencias Bioquimicas, UNAM.

Asesor: Gosset Lagarda, Guillermo

20 - Meza Mora, Eugenio Arturo (2013). Estudio sobre el efecto de la actividad de piruvato cinasa en la distribución de flujos en el metabolismo central de una cepa de Escherichia coli que carece del sistema de fosfotransferasa. Instituto de Biotecnologia, Doctorado en Ciencias Bioquímicas, UNAM.

Asesor: Gosset Lagarda, G.

21 - Munoz Arellano, Ana Joyce (2010). Biosintesis de 3,4dihidroxiLfenilalanina (Ldopa) en Escherichia coli a partir de glucosa . Instituto de Biotecnologia, Maestria en Ciencias Bioquimicas, UNAM.

Asesor: Gosset Lagarda, Guillermo

22 - Echeverria Serur, Alberto (2010). Caracterizacion de versiones mutantes del gen melA de Rhizobium etli expresadas en Escherichia coli . Facultad de Ciencias, Licenciatura en Biología, UNAM. *

Asesor: Gosset Lagarda, Guillermo

23 - Chavez Bejar, Maria Ines (2010). Ingenieria de vias metabolicas para la produccion de tirosina y melanina a partir de glucosa en Escherichia coli . Instituto de Biotecnologia, Doctorado en Ciencias Bioquimicas, UNAM.

Asesor: Gosset Lagarda, Guillermo

24 - Sabido Ramos, Andrea (2009). Construccion y caracterizacion de un sistema para la expresion cromosomal de genes en Escherichia coli . Instituto de Biotecnologia, Maestria en Ciencias Bioquimicas, UNAM.

Asesor: Gosset Lagarda, Guillermo

25 - Robledo Arratia, Luis (2008). Generacion y caracterizacion de una mutante de la tirosinasa de Rhizobium etli . Facultad de Ciencias, Licenciatura en Biología, UNAM. *

Asesor: Gosset Lagarda, Guillermo

26 - Licona Cassani, Cuauhtemoc (2008). Efecto de la inhibicion de actividades enzimaticas que consumen fosfoenolpiruvato (PEP) sobre la capacidad de sintesis de shikimato en Bacillus subtilis . Instituto de Biotecnologia, Maestria en Ciencias Bioquimicas, UNAM.

Asesor: Gosset Lagarda, Guillermo

27 - Pariente Perez, Telma Olivia (2007). Construccion y caracterizacion de una cepa derivada de Bacillus subtilis que pueda utilizar xilosa como unica fuente de carbono . Facultad de Ciencias, Licenciatura en Biología, UNAM. *

Asesor: Gosset Lagarda, Guillermo, Romero Garcia, Aida Susana

28 - Munoz Arellano, Ana Joyce (2007). Estudio de la represion catabolica en una cepa enteropatogena de Escherichia coli que tiene la capacidad de utilizar sacarosa como unica fuente de carbono . Facultad de Ciencias, Licenciatura en Biología, UNAM. *

Asesor: Gosset Lagarda, Guillermo

29 - Gonzalez Chavez, Ricardo (2007). Analisis funcional del regulon de sacarosa en cepas patogenas de Escherichia coli. Facultad de Ciencias, Licenciatura en Biología, UNAM. *

Asesor: Gosset Lagarda, Guillermo

30 - Sabido Ramos, Andrea (2006). Generacion y caracterizacion de cepas de Escherichia coli productoras de antranilato y catecol . Facultad de Ciencias, Licenciatura en Biología, UNAM. *

Asesor: Gosset Lagarda, Guillermo

31 - Pinero Fernandez, Silvia (2006). Papel de la tirosinasa de Rhizobium etli en su eficiencia simbiotica y resistencia a estres. Instituto de Biotecnologia, Doctorado en Ciencias Bioquimicas, UNAM.

Asesor: Gosset Lagarda, Guillermo

32 - Silva Rincon, Elsa Patricia (2005). Desarrollo y caracterizacion de cepas de Escherichia coli disenadas para la produccion de antranilato y catecol . Instituto de Biotecnologia, Maestria en Ciencias Bioquimicas, UNAM.

Asesor: Gosset Lagarda, Guillermo

33 - Cortazar Martinez, Adriana (2005). Efecto de la inactivizacion de las isoenzimas de piruvato cinasa sobre el metabolismo central y la capacidad de sintesis de compuestos aromaticos en cepas de escherichia coli que carecen del sistema de fosfotransferasa . Instituto de Biotecnologia, Maestría en Ciencias (Bioquímica), UNAM.

Asesor: Gosset Lagarda, Guillermo

34 - Sirena Sanchez, Noemi (2004). Caracterizacion de la proteina codificada por el gen me1A de Rhizobium etli . Facultad de Ciencias, Licenciatura en Biología, UNAM. *

Asesor: Gosset Lagarda, Guillermo

35 - Baez Viveros, Jose Luis (2004). Ingenieria metabolica y evolucion dirigida de proteinas aplicadas a la produccion de fenilalanina en Escherichia coli . Instituto de Biotecnologia, Doctorado en Ciencias Bioquimicas, UNAM.

Asesor: Gosset Lagarda, Guillermo

36 - Orencio Trejo, Virginia Montserrat (2003). Estudio sobre la regulacion de los operones xy1AB y xy1FGH de Escherichia coli sivestre y carente del sistema de fosfotransferasa (PTS) . Instituto de Biotecnologia, Maestria en Ciencias (Bioquimica), UNAM.

Asesor: Gosset Lagarda, Guillermo

37 - Hernandez Montalvo, Veronica (2001). Caracterizacion y manipulacion del transporte de azucares en cepas de Escherichia coli deficientes del sistema de la fosfotransferasa (PTS). Instituto de Biotecnologia, Doctorado en Ciencias (Bioquimica), UNAM.

Asesor: Gosset Lagarda, Guillermo

38 - Baez Viveros, Jose Luis (1999). Efecto de la inactivacion del sistema fosfotransferasa en el rendimiento de aromaticos a partir de glucosa en Escherichia coli . Instituto de Biotecnologia, Maestría en Ciencias (Bioquímica), UNAM.

Asesor: Gosset Lagarda, Guillermo

39 - Romero Perez, Diego (1998). Caracterizacion, clonacion y expresion del gene udhA que codifica para una trashidrogenasa soluble en E. coli. Facultad de Ciencias, Licenciatura en Biología, UNAM. *

Asesor: Gosset Lagarda, Guillermo

Publicaciones

Total de publicaciones: 172

Tipo
Fecha

Artículos

Artículo

40 - Martinez,J.A., Bouchat,R., Gallet de St Aurin,T., Martinez,L.M., Caspeta,L., Telek,S., Zicler,A., Gosset,G., Delvigne,F. (2025). Automated adjustment of metabolic niches enables the control of natural and engineered microbial co-cultures. Trends in Biotechnology, 43 (5), 1116-1139.

Artículo

41 - Molina-Vazquez,E.R., Caspeta,L., Gosset,G., Martinez,A. (2025). Tailoring Escherichia coli BL21 (DE3) for preferential xylose utilization via metabolic and regulatory engineering. Applied Microbiology and Biotechnology, 109 (1), 54.

Artículo

42 - Perez-Morales,G., Martinez-Conde,K.V., Caspeta,L., Merino,E., Cevallos,M.A., Gosset,G., Martinez,A. (2025). Thermally adapted Escherichia coli keeps transcriptomic response during temperature upshift exposure. Applied Microbiology and Biotechnology, 109 (1), 120.

Artículo communication

43 - Pohlen,L., Garcia,E., Martinez,L.M., FLORES,N., Buchs,J., Gosset,G., Lara,A.R. (2025). Sigma factors as potential targets to enhance recombinant protein expression. Biotechnology and Bioengineering, 122 (6), 1598-1607.

Article

44 - Sayago,J., Martinez,L.M., Hernandez,G., Gosset,G. (2025). Biotechnological melanin synthesized from tyrosine vs other precursors significantly affects its electrochemical response. AIP Advances, 15 (1), 015003.

Artículo in press

45 - Vallejo-Giraldo,A., Martinez,L.M., FLORES,N., Hernandez-Chavez,G., Cueto,F., Martinez,A., Corona-Gonzalez,R.I., Gosset,G. (2025). Construction and Characterization of Novel Shuttle Expression Vectors for Actinobacillus succinogenes. Biotechnology and Applied Biochemistry, Feb 17 [Online ahead of print].

Artículo

46 - Varela-Perez,N.M., Vallejo-Giraldo,A., Fragoso-Jimenez,J.C., Martinez,L.M., Hernandez-Chavez,G., Gutierrez-Rios,R.M., Martinez,A., Marcellin,E., Vieille,C., Gosset,G. (2025). Insights into lactose catabolism and its regulation in Actinobacillus succinogenes. Journal of Applied Microbiology, 136 (6), lxaf134.

Artículo

47 - de la Cruz,M., Kunert,F., Taymaz-Nikerel,H., Sigala,J.C., Gosset,G., Buchs,J., Lara,A.R. (2024). Increasing the Pentose Phosphate Pathway Flux to Improve Plasmid DNA Production in Engineered E. coli. Microorganisms, 12 (1), 150.

Artículo

48 - Escalante,A., Astudillo,F., Larios,V., FLORES,N., Gosset,G., Bolivar,F. (2024). The complete genome of Escherichia coli JM101 assembled with a combination of Nanopore and Illumina platforms. Microbiology Resource Announcements, 13 (2), e0097323.

Articulo

49 - Lara,A.R., Kunert,F., Vandenbroucke,V., Taymaz-Nikerel,H., Martinez,L.M., Sigala,J.C., Delvigne,F., Gosset,G., Buchs,J. (2024). Transport-controlled growth decoupling for self-induced protein expression with a glycerol repressible genetic circuit. Biotechnology and Bioengineering, 121 (6), 1789-1802.

Artículo

50 - Lara,A.R., Utrilla,J., Martinez,L.M., Krausch,N., Kaspersetz,L., Hidalgo,D., Cruz-Bournazou,N., Neubauer,P., Sigala,J.C., Gosset,G., Buchs,J. (2024). Recombinant protein expression in proteome-reduced cells under aerobic and oxygen-limited regimes. Biotechnology and Bioengineering, 121 (4), 1216-1230.

Artículo

51 - Perez-Morales,G., Caspeta,L., Merino,E., Cevallos,M.A., Gosset,G., Martinez,A. (2024). Simultaneous saccharification and fermentation for D-lactic acid production using a metabolically engineered Escherichia coli adapted to high temperature. Biotechnology for Biofuels and Bioproducts, 17 (1), 132.

Artículo

52 - Alcala-Alcala,S., Casarrubias-Anacleto,J.E., Mondragon-Guillen,M., Tavira-Montalvan,C.A., Bonilla-Hernandez,M., Gomez-Galicia,D.L., Gosset,G., Meneses-Acosta,A. (2023). Melanin Nanoparticles Obtained from Preformed Recombinant Melanin by Bottom-Up and Top-Down Approaches. Polymers (Basel), 15 (10), 2381.

Revision

53 - Carreon-Rodriguez,O.E., Gosset,G., Escalante,A., Bolivar,F. (2023). Glucose Transport in Escherichia coli: From Basics to Transport Engineering. Microorganisms, 11 (6), 1588.

Artículo

54 - Krausch,N., Kaspersetz,L., Gaytan-Castro,R.D., Schermeyer,M.T., Lara,A.R., Gosset,G., Cruz Bournazou,M.N., Neubauer,P. (2023). Model-Based Characterization of E. coli Strains with Impaired Glucose Uptake. Bioengineering (Basel), 10 (7).

Artículo

55 - Fragoso-Jimenez,J.C., Gutierrez-Rios,R.M., FLORES,N., Martinez,A., Lara,A.R., Delvigne,F., Gosset,G. (2022). Glucose consumption rate-dependent transcriptome profiling of Escherichia coli provides insight on performance as microbial factories. Microbial Cell Factories, 21 (1), 189.

Artículo

56 - Rodriguez-Ochoa,J.I., Fragoso-Jimenez,J.C., FLORES,N., Martinez,L.M., Bolivar,F., Martinez,A., Gosset,G. (2022). Global transcriptomic response of Escherichia coli to p-coumaric acid. Microbial Cell Factories, 21 (1), 148.

Artículo

57 - Velazquez,D., Sigala,J.C., Martinez,L.M., Gaytan,P., Gosset,G., Lara,A.R. (2022). Glucose transport engineering allows mimicking fed-batch performance in batch mode and selection of superior producer strains. Microbial Cell Factories, 21 (1), 183.

Revisión

58 - Escalante,A., Mendoza-Flores,R., Gosset,G., Bolivar,F. (2021). The aminoshikimic acid pathway in bacteria as source of precursors for the synthesis of antibacterial and antiviral compounds. Journal of Industrial Microbiology & Biotechnology, 48 (9-10), kuab053.

Artículo

59 - Sierra-Ibarra,E., Leal-Reyes,L.J., Huerta-Beristain,G., Hernandez-Orihuela,A.L., Gosset,G., Martinez-Antonio,A., Martinez,A. (2021). Limited oxygen conditions as an approach to scale-up and improve D and L-lactic acid production in mineral media and avocado seed hydrolysates with metabolically engineered Escherichia coli. Bioprocess and Biosystems Engineering, 44, 379-389.

Artículo

60 - Carmona,S.B., FLORES,N., Martinez-Romero,E., Gosset,G., Bolivar,F., Escalante,A. (2020). Evolution of an Escherichia coli PTS(-) strain: a study of reproducibility and dynamics of an adaptive evolutive process. Applied Microbiology and Biotechnology, 104, 9309?9325.

Artículo

61 - Fernandez-Sandoval,M.T., Galindez-Mayer,J., Bolivar,F., Gosset,G., Ramirez,O.T., Martinez,A. (2019). Xylose-glucose co-fermentation to ethanol by Escherichia coli strain MS04 using single- and two-stage continuous cultures under micro-aerated conditions. Microbial Cell Factories, 18 (1), 145.

Artículo

62 - Fragoso-Jimenez,J.C., Baert,J., Nguyen,T.M., Liu,W., Sassi,H., Goormaghtigh,F., Van Melderen L., Gaytan,P., Hernandez-Chavez,G., Martinez,A., Delvigne,F., Gosset,G. (2019). Growth-dependent recombinant product formation kinetics can be reproduced through engineering of glucose transport and is prone to phenotypic heterogeneity. Microbial Cell Factories, 18 (1), 26.

Revisión

63 - Hernandez-Chavez,G., Martinez,A., Gosset,G. (2019). Metabolic engineering strategies for caffeic acid production in Escherichia coli. Electronic Journal of Biotechnology, 38, 19-26.

Revisión

64 - Martinez,L.M., Martinez,A., Gosset,G. (2019). Production of Melanins With Recombinant Microorganisms. Frontiers in Bioengineering and Biotechnology, 7, 285.

Artículo

65 - Salcedo-Vite,K., Sigala,J.C., Segura,D., Gosset,G., Martinez,A. (2019). Acinetobacter baylyi ADP1 growth performance and lipid accumulation on different carbon sources. Applied Microbiology and Biotechnology, 103 (15), 6217-6229.

Artículo

66 - Sassi,H., Nguyen,T.M., Telek,S., Gosset,G., Grunberger,A., Delvigne,F. (2019). Segregostat: a novel concept to control phenotypic diversification dynamics on the example of Gram-negative bacteria. Microbial Biotechnology, 12 (5), 1064-1075.

Artículo

67 - Martinez,J.A., Rodriguez,A., Moreno,F., FLORES,N., Lara,A.R., Ramirez,O.T., Gosset,G., Bolivar,F. (2018). Metabolic modeling and response surface analysis of an Escherichia coli strain engineered for shikimic acid production. BMC Systems Biology, 12 (1), 102.

Artículo

68 - Salas-Navarrete, C., Hernandez-Chavez, G., Flores, N., Martinez, L.M., Martinez, A., Bolivar, F., Barona-Gomez, F., Gosset, G. (2018). Increasing pinosylvin production in Escherichia coli by reducing the expression level of the gene fabI-encoded enoyl-acyl carrier protein reductase. Electronic Journal of Biotechnology, 33, 11-16.

Artículo

69 - Fernandez-Sandoval, M.T., Galindez-Mayer, J., Moss-Acosta, C.L., Gosset, G., Martinez, A. (2017). Volumetric oxygen transfer coefficient as a means of improving volumetric ethanol productivity and a criterion for scaling up ethanol production with Escherichia coli. Journal of Chemical Technology and Biotechnology, 92 (5), 981-989.

Artículo

70 - Garcia, S., Flores, N., de Anda, R., Hernandez, G., Gosset, G., Bolivar, F., Escalante, A. (2017). The Role of the ydiB Gene, Which Encodes Quinate/Shikimate Dehydrogenase, in the Production of Quinic, Dehydroshikimic and Shikimic Acids in a PTS- Strain of Escherichia coli. Journal of Molecular Microbiology and Biotechnology, 27 (1), 11-21.

Artículo

71 - Huerta-Beristain, G., Cabrera-Ruiz, R., Hernandez-Chavez, G., Bolivar, F., Gosset, G., Martinez, A. (2017). Metabolic engineering and adaptive evolution of Escherichia coli KO11 for ethanol production through the Entner-Doudoroff and the pentose phosphate pathways. Journal of Chemical Technology and Biotechnology, 92 (5), 990-996.

Artículo

72 - Rodriguez, A., Martinez, J.A., Millard, P., Gosset, G., Portais, J.C., Letisse, F., Bolivar, F. (2017). Plasmid-encoded biosynthetic genes alleviate metabolic disadvantages while increasing glucose conversion to shikimate in an engineered Escherichia coli strain. Biotechnology and Bioengineering, 114 (6), 1319-1330.

Artículo

73 - Baert,J., Delepierre,A., Telek,S., Fickers,P., Toye,D., Delamotte,A., Lara,A.R., Jaen,K.E., Gosset,G., Jensen,P.R., Delvigne,F. (2016). Microbial population heterogeneity versus bioreactor heterogeneity: Evaluation of Redox Sensor Green as an exogenous metabolic biosensor. Engineering in Life Sciences, 16 (7), 643-651.

Artículo

74 - Camacho-Zaragoza,J.M., Hernandez-Chavez,G., Moreno-Avitia,F., Ramirez-Iniguez,R., Martinez,A., Bolivar,F., Gosset,G. (2016). Engineering of a microbial coculture of Escherichia coli strains for the biosynthesis of resveratrol. Microbial Cell Factories, 15 (1), 163.

Artículo

75 - Mejia-Caballero,A., de Anda,R., Hernandez-Chavez,G., Rogg,S., Martinez,A., Bolivar,F., Castano,V.M., Gosset,G. (2016). Biosynthesis of catechol melanin from glycerol employing metabolically engineered Escherichia coli. Microbial Cell Factories, 15 (1), 161.

Artículo

76 - Utrilla,J., Vargas-Tah,A., Trujillo-Martinez,B., Gosset,G., Martinez,A. (2016). Production of d-lactate from sugarcane bagasse and corn stover hydrolysates using metabolic engineered Escherichia coli strains. Bioresource Technology, 220, 208-214.

Revisión

77 - Carmona,S.B., Moreno,F., Bolivar,F., Gosset,G., Escalante,A. (2015). Inactivation of the PTS as a Strategy to Engineer the Production of Aromatic Metabolites in Escherichia coli. Journal of Molecular Microbiology and Biotechnology, 25 (2-3), 195-208.

Artículo

78 - Vargas-Tah,A., Moss-Acosta,C.L., Trujillo-Martinez,B., Tiessen,A., Lozoya-Gloria,E., Orencio-Trejo,M., Gosset,G., Martinez,A. (2015). Non-severe thermochemical hydrolysis of stover from white corn and sequential enzymatic saccharification and fermentation to ethanol. Bioresource Technology, 198, 611-618.

Artículo

79 - Vargas-Tah,A., Gosset,G. (2015). Production of Cinnamic and p-Hydroxycinnamic Acids in Engineered Microbes. Frontiers in Bioengineering and Biotechnology, 3, 116.

Artículo

80 - Vargas-Tah,A., Martinez,L., Hernandez-Chavez,G., Rocha,M., Martinez,A., Bolivar,F., Gosset,G. (2015). Production of cinnamic and p -hydroxycinnamic acid from sugar mixtures with engineered Escherichia coli. Microbial Cell Factories, 14 (1), 185.

Artículo

81 - Balderas-Hernandez,V.E., Trevino-Quintanilla,L.G., Hernandez-Chavez,G., Martinez,A., Bolivar,F., Gosset,G. (2014). Catechol biosynthesis from glucose in Escherichia coli anthranilate-overproducer strains by heterologous expression of anthranilate 1,2-dioxygenase from Pseudomonas aeruginosa PAO1. Microbial Cell Factories, 13 (1), 136.

Artículo

82 - Centeno-Leija,S., Huerta-Beristain,G., Giles-Gomez,M., Bolivar,F., Gosset,G., Martinez,A. (2014). Improving poly-3-hydroxybutyrate production in Escherichia coli by combining the increase in the NADPH pool and acetyl-CoA availability. Antonie Van Leeuwenhoek, 105 (4), 687-696.

Artículo

83 - Cortes-Tolalpa,L., Gutierrez-Rios,R.M., Martinez,L.M., de Anda,R., Gosset,G., Bolivar,F., Escalante,A. (2014). Global transcriptomic analysis of an engineered Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system during shikimic acid production in rich culture medium. Microbial Cell Factories, 13 (1), 28.

Artículo

84 - Licona-Cassani,C., Lara,A.R., Cabrera-Valladares,N., Escalante,A., Hernandez-Chavez,G., Martinez,A., Bolivar,F., Gosset,G. (2014). Inactivation of Pyruvate Kinase or the Phosphoenolpyruvate: Sugar Phosphotransferase System Increases Shikimic and Dehydroshikimic Acid Yields from Glucose in Bacillus subtilis. Journal of Molecular Microbiology and Biotechnology, 24 (1), 37-45.

Artículo

85 - Munoz-Gutierrez,I., Moss-Acosta,C., Trujillo-Martinez,B., Gosset,G., Martinez,A. (2014). Ag43-mediated display of a thermostable á-glucosidase in Escherichia coli and its use for simultaneous saccharification and fermentation at high temperatures. Microbial Cell Factories, 13 (1), 106.

Revisión

86 - Rodriguez,A., Martinez,J.A., FLORES,N., Escalante,A., Gosset,G., Bolivar,F. (2014). Engineering Escherichia coli to overproduce aromatic amino acids and derived compounds. Microbial Cell Factories, 13 (1), 126.

Artículo

87 - Ruiz-Villafan,B., Rodriguez-Sanoja,R., Aguilar-Osorio,G., Gosset,G., Sanchez,S. (2014). Glucose kinases from Streptomyces peucetius var. caesius. Applied Microbiology and Biotechnology, 98 (13), 6061-6071.

Artículo

88 - Sabido,A., Sigala,J.C., Hernandez-Chavez,G., FLORES,N., Gosset,G., Bolivar,F. (2014). Physiological and transcriptional characterization of Escherichia coli strains lacking interconversion of phosphoenolpyruvate and pyruvate when glucose and acetate are coutilized. Biotechnology and Bioengineering, 111 (6), 1150-1160.

Artículo

89 - Wunderlich,M., Taymaz-Nikerel,H., Gosset,G., Ramirez,O.T., Lara,A.R. (2014). Effect of growth rate on plasmid DNA production and metabolic performance of engineered Escherichia coli strains. Journal of Bioscience and Bioengineering, 117 (3), 336-342.

Artículo

90 - Centeno-Leija,S., Utrilla,J., FLORES,N., Rodriguez,A., Gosset,G., Martinez,A. (2013). Metabolic and transcriptional response of Escherichia coli with a NADP-dependent glyceraldehyde 3-phosphate dehydrogenase from Streptococcus mutans. Antonie Van Leeuwenhoek, 104 (6), 913-924.

Artículo

91 - Chavez-Bejar,M.I., Balderas-Hernandez,V.E., Gutierrez-Alejandre,A., Martinez,A., Bolivar,F., Gosset,G. (2013). Metabolic engineering of Escherichia coli to optimize melanin synthesis from glucose. Microbial Cell Factories, 12 (1), 108.

Artículo

92 - Fuentes,L.G., Lara,A.R., Martinez,L.M., Ramirez,O.T., Martinez,A., Bolivar,F., Gosset,G. (2013). Modification of glucose import capacity in Escherichia coli: physiologic consequences and utility for improving DNA vaccine production. Microbial Cell Factories, 12 (1), 42.

Artículo

93 - Rodriguez,A., Martinez,J.A., Baez-Viveros,J.L., FLORES,N., Hernandez-Chavez,G., Ramirez,O.T., Gosset,G., Bolivar,F. (2013). Constitutive expression of selected genes from the pentose phosphate and aromatic pathways increases the shikimic acid yield in high-glucose batch cultures of an Escherichia coli strain lacking PTS and pykF. Microbial Cell Factories, 12 (1), 86.

Artículo

94 - Sabido,A., Martinez,L.M., de Anda,R., Martinez,A., Bolivar,F., Gosset,G. (2013). A novel plasmid vector designed for chromosomal gene integration and expression: Use for developing a genetically stable Escherichia coli melanin production strain. Plasmid, 69 (1), 16-23.

Artículo

95 - Soria,S., de Anda,R., FLORES,N., Romero-Garcia,S., Gosset,G., Bolivar,F., Baez-Viveros,J.L. (2013). New insights on transcriptional responses of genes involved in carbon central metabolism, respiration and fermentation to low ATP levels in Escherichia coli. Journal of Basic Microbiology, 53 (4), 365-380.

Artículo

96 - Aguilar,C., Escalante,A., FLORES,N., de Anda,R., Riveros-McKay,F., Gosset,G., Morett,E., Bolivar,F. (2012). Genetic changes during a laboratory adaptive evolution process that allowed fast growth in glucose to an Escherichia coli strain lacking the major glucose transport system. BMC Genomics, 13 (1), 385.

Artículo

97 - Borja,G.M., Meza-Mora E., Barron,B., Gosset,G., Ramirez,O.T., Lara,A.R. (2012). Engineering Escherichia coli to increase plasmid DNA production in high cell-density cultivations in batch mode. Microbial Cell Factories, 11 (1), 132.

Artículo

98 - Cabrera-Valladares,N., Martinez,L.M., FLORES,N., Hernandez-Chavez,G., Martinez,A., Bolivar,F., Gosset,G. (2012). Physiologic Consequences of Glucose Transport and Phosphoenolpyruvate Node Modifications in Bacillus subtilis 168. Journal of Molecular Microbiology and Biotechnology, 22 (3), 177-197.

Revisión

99 - Chavez-Bejar,M.I., Baez-Viveros,J.L., Martinez,A., Bolivar,F., Gosset,G. (2012). Biotechnological production of l-tyrosine and derived compounds. Process Biochemistry, 47 (7), 1017-1026.

Revisión

100 - Escalante,A., Salinas-Cervantes A., Gosset,G., Bolivar,F. (2012). Current knowledge of the Escherichia coli phosphoenolpyruvate-carbohydrate phosphotransferase system: peculiarities of regulation and impact on growth and product formation. Applied Microbiology and Biotechnology, 94 (6), 1483-1494.

Artículo

101 - Fernandez-Sandoval,M.T., Huerta-Beristain,G., Trujillo-Martinez,B., Bustos,P., Gonzalez,V., Bolivar,F., Gosset,G., Martinez,A. (2012). Laboratory metabolic evolution improves acetate tolerance and growth on acetate of ethanologenic Escherichia coli under non-aerated conditions in glucose-mineral medium. Applied Microbiology and Biotechnology, 96 (5), 1291-1300.

Artículo

102 - Martinez-Gomez,K., FLORES,N., Castaneda,H.M., Martinez-Batallar,G., Hernandez-Chavez,G., Ramirez,O.T., Gosset,G., Encarnacion,S., Bolivar,F. (2012). New insights into Escherichia coli metabolism: carbon scavenging, acetate metabolism and carbon recycling responses during growth on glycerol. Microbial Cell Factories, 11 (1), 46.

Artículo

103 - Meza,E., Becker,J., Bolivar,F., Gosset,G., Wittmann,C. (2012). Consequences of phosphoenolpyruvate:sugar phosphotranferase system and pyruvate kinase isozymes inactivation in central carbon metabolism flux distribution in Escherichia coli. Microbial Cell Factories, 11 (1), 127.

Artículo

104 - Munoz-Gutierrez,I., Oropeza,R., Gosset,G., Martinez,A. (2012). Cell surface display of a beta-glucosidase employing the type V secretion system on ethanologenic Escherichia coli for the fermentation of cellobiose to ethanol. Journal of Industrial Microbiology & Biotechnology, 39 (8), 1141-1152.

Artículo; Actas Paper

105 - Pablos,T.E., Soto,R., Mora,E.M., Le Borgne,S., Ramirez,O.T., Gosset,G., Lara,A.R. (2012). Enhanced production of plasmid DNA by engineered Escherichia coli strains. Journal of Biotechnology, 158 (4), 211-214.

Artículo

106 - Utrilla,J., Licona-Cassani,C., Marcellin,E., Gosset,G., Nielsen,L.K., Martinez,A. (2012). Engineering and adaptive evolution of Escherichia coli for d-lactate fermentation reveals GatC as a xylose transporter. Metabolic Engineering, 14 (5), 469-476.

Artículo

107 - Balderas-Hernandez,V.E., Hernandez-Montalvo,V., Bolivar,F., Gosset,G., Martinez,A. (2011). Adaptive Evolution of Escherichia coli Inactivated in the Phosphotransferase System Operon Improves Co-utilization of Xylose and Glucose Under Anaerobic Conditions. Applied Biochemistry and Biotechnology, 163 (4), 485-496.

Artículo

108 - Lopes,M.S.G., Gosset,G., Rocha,R.C.S., Gomez,J.G.C., Ferreira da Silva,L. (2011). PHB Biosynthesis in Catabolite Repression Mutant of Burkholderia sacchari. Current Microbiology, 63 (4), 319-326.

Artículo

109 - Munoz,A.J., Hernandez-Chavez,G., de Anda,R., Martinez,A., Bolivar,F., Gosset,G. (2011). Metabolic engineering of Escherichia coli for improving L: -3,4-dihydroxyphenylalanine (L: -DOPA) synthesis from glucose. Journal of Industrial Microbiology & Biotechnology, 38 (11), 1845-1852.

Artículo

110 - Pablos,T.E., Mora,E.M., Le Borgne,S., Ramirez,O.T., Gosset,G., Lara,A.R. (2011). Vitreoscilla hemoglobin expression in engineered Escherichia coli: Improved performance in high cell-density batch cultivations. Biotechnology Journal, 6 (8), 993-1002.

Artículo

111 - Soto,R., Caspeta,L., Barron,B., Gosset,G., Ramirez,O.T., Lara,A.R. (2011). High cell-density cultivation in batch mode for plasmid DNA production by a metabolically engineered E. coli strain with minimized overflow metabolism. Biochemical Engineering Journal, 56 (3), 165-171.

Artículo

112 - Tierrafria,V.H., Ramos-Aboites,H.E., Gosset,G., Barona-Gomez,F. (2011). Disruption of the siderophore-binding desE receptor gene in Streptomyces coelicolor A3(2) results in impaired growth in spite of multiple iron-siderophore transport systems. Microbial Biotechnology, 4 (2), 275-285.

Artículo

113 - Escalante,A., Calderon,R., Valdivia,A., de Anda,R., Hernandez,G., Ramirez,O.T., Gosset,G., Bolivar,F. (2010). Metabolic engineering for the production of shikimic acid in an evolved Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system. Microbial Cell Factories, 9 (1), 21.

Artículo

114 - Balderas-Hernandez,V.E., Sabido-Ramos,A., Silva,P., Cabrera-Valladares,N., Hernandez-Chavez,G., Baez-Viveros,J.L., Martinez,A., Bolivar,F., Gosset,G. (2009). Metabolic engineering for improving anthranilate synthesis from glucose in Escherichia coli. Microbial Cell Factories, 8 (1), 19.

Revisión

115 - Gosset,G. (2009). Production of aromatic compounds in bacteria. Current Opinion in Biotechnology, 20 (6), 651-658.

Artículo

116 - Olvera,L., Mendoza-Vargas,A., FLORES,N., Olvera,M., Sigala,J.C., Gosset,G., Morett,E., Bolivar,F. (2009). Transcription Analysis of Central Metabolism Genes in Escherichia coli. Possible Roles of a38 in Their Expression, as a Response to Carbon Limitation. PLoS ONE, 4 (10), e7466.

Artículo

117 - Romero-Garcia,S., Hernandez-Bustos,C., Merino,E., Gosset,G., Martinez,A. (2009). Homolactic fermentation from glucose and cellobiose using Bacillus subtilis. Microbial Cell Factories, 8 (1), 23.

Artículo

118 - Sigala,J.C., Flores,S., FLORES,N., Aguilar,C., de Anda,R., Gosset,G., Bolivar,F. (2009). Acetate Metabolism in Escherichia coli Strains Lacking Phosphoenolpyruvate: Carbohydrate Phosphotransferase System; Evidence of Carbon Recycling Strategies and Futile Cycles. Journal of Molecular Microbiology and Biotechnology, 16 (3-4), 224-235.

Artículo

119 - Utrilla,J., Gosset,G., Martinez,A. (2009). ATP limitation in a pyruvate formate lyase mutant of Escherichia coli MG1655 increases glycolytic flux to D: -lactate. Journal of Industrial Microbiology & Biotechnology, 36 (8), 1057-1062.

Artículo

120 - Vazquez,C.D., Freyre-Gonzalez,J.A., Gosset,G., Loza,J.A., Gutierrez-Rios,R.M. (2009). Identification of network topological units coordinating the global expression response to glucose in Bacillus subtilis and its comparison to Escherichia coli. BMC Microbiology, 9 (1), 176.

Artículo

121 - Chavez-Bejar,M.I., Lara,A.R., Lopez,H., Hernandez-Chavez,G., Martinez,A., Ramirez,O.T., Bolivar,F., Gosset,G. (2008). Metabolic engineering of Escherichia coli for L-tyrosine production by the expression of the genes coding for the chorismate mutase domain from native P-protein and a cyclohexadienyl dehydrogenase from Zymomonas mobilis. Applied and Environmental Microbiology, 74 (10), 3284-3290.

Artículo

122 - Escalante,A., Giles-Gomez,M., Hernandez,G., Cordova-Aguilar,M.S., Lopez-Munguia,A., Gosset,G., Bolivar,F. (2008). Analysis of bacterial community during the fermentation of pulque, a traditional Mexican alcoholic beverage, using a polyphasic approach. International Journal of Food Microbiology, 124 (2), 126-134.

Artículo

123 - FLORES,N., Escalante,A., de Anda,R., Baez-Viveros,J.L., Merino,E., Franco,B., Georgellis,D., Gosset,G., Bolivar,F. (2008). New Insights into the Role of Sigma Factor RpoS as Revealed in Escherichia coli Strains Lacking the Phosphoenolpyruvate:Carbohydrate Phosphotransferase System. Journal of Molecular Microbiology and Biotechnology, 14 (4), 176-192.

Artículo

124 - Huerta-Beristain,G., Utrilla,J., Hernandez-Chavez,G., Bolivar,F., Gosset,G., Martinez,A. (2008). Specific ethanol production rate in ethanologenic Escherichia coli strain KO11 Is limited by pyruvate decarboxylase. Journal of Molecular Microbiology and Biotechnology, 15 (1), 55-64.

Artículo

125 - Lara,A.R., Caspeta,L., Gosset,G., Bolivar,F., Ramirez,O.T. (2008). Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: An alternative to fed-batch cultures. Biotechnology and Bioengineering, 99 (4), 893-901.

Artículo

126 - Martinez,K., de Anda,R., Hernandez,G., Escalante,A., Gosset,G., Ramirez,O.T., Bolivar,F.G. (2008). Coutilization of glucose and glycerol enhances the production of aromatic compounds in an Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system. Microbial Cell Factories, 7 (1), 1.

Artículo

127 - Orencio-Trejo,M., FLORES,N., Escalante,A., Hernandez-Chavez,G., Bolivar,F., Gosset,G., Martinez,A. (2008). Metabolic regulation analysis of an ethanologenic Escherichia coli strain based on RT-PCR and enzymatic activities. Biotechnology for Biofuels, 1 (1), 8.

Artículo

128 - Baez-Viveros,J.L., FLORES,N., Suarez,K., Castillo-Espana,P., Bolivar,F., Gosset,G. (2007). Metabolic transcription analysis of engineered Escherichia coli strains that overproduce L-phenylalanine. Microbial Cell Factories, 6 (1), 30.

Artículo

129 - FLORES,N., Leal,L., Sigala,J.C., de Anda,R., Escalante,A., Martinez,A., Ramirez,O.T., Gosset,G., Bolivar,F. (2007). Growth Recovery on Glucose under Aerobic Conditions of an Escherichia coli Strain Carrying a Phosphoenolpyruvate:Carbohydrate Phosphotransferase System Deletion by Inactivating arcA and Overexpressing the Genes Coding for Glucokinase and Galactose Permease. Journal of Molecular Microbiology and Biotechnology, 13 (1-3), 105-116.

Artículo

130 - Gutierrez-Rios,R.M., Freyre-Gonzalez,J.A., Resendis,O., Collado-Vides,J., Saier,M., Gosset,G. (2007). Identification of regulatory network topological units coordinating the genome-wide transcriptional response to glucose in Escherichia coli. BMC Microbiology, 7 (1), 53.

Artículo

131 - Pinero,S., Rivera,J., Romero,D., Cevallos,M.A., Martinez,A., Bolivar,F., Gosset,G. (2007). Tyrosinase from Rhizobium etli Is Involved in Nodulation Efficiency and Symbiosis-Associated Stress Resistance. Journal of Molecular Microbiology and Biotechnology, 13 (1-3), 35-44.

Artículo

132 - Romero,S., Merino,E., Bolivar,F., Gosset,G., Martinez,A. (2007). Metabolic engineering of Bacillus subtilis for ethanol production: Lactate dehydrogenase plays a key role in the fermentative metabolism. Applied and Environmental Microbiology, 73 (16), 5190-5198.

Artículo

133 - Trevino-Quintanilla,L.G., Escalante,A., Caro,A.D., Martinez,A., Gonzalez,R., Puente,J.L., Bolivar,F., Gosset,G. (2007). The Phosphotransferase System-Dependent Sucrose Utilization Regulon in Enteropathogenic Escherichia coli Strains Is Located in a Variable Chromosomal Region Containing iap Sequences. Journal of Molecular Microbiology and Biotechnology, 13 (1-3), 117-125.

Artículo

134 - Vazquez-Limon,C., Vega-Badillo,J., Martinez,A., Espinosa-Molina,G., Gosset,G., Soberon,X., Lopez-Munguia,A., Osuna,J. (2007). Growth rate of a non-fermentative Escherichia coli strain is influenced by NAD(+) regeneration. Biotechnology Letters, 29 (12), 1857-1863.

Artículo

135 - Cabrera-Valladares,N., Martinez,A., Pinero,S., Lagunas-Munoz,V.H., Tinoco,R., de Anda,R., Vazquez-Duhalt,R., Bolivar,F., Gosset,G. (2006). Expression of the melA gene from Rhizobium etli CFN42 in Escherichia coli and characterization of the encoded tyrosinase. Enzyme and Microbial Technology, 38 (6), 772-779.

Artículo

136 - de Anda,R., Lara,A.R., Hernandez,V., Hernandez-Montalvo,V., Gosset,G., Bolivar,F., Ramirez,O.T. (2006). Replacement of the glucose phosphotransferase transport system by galactose permease reduces acetate accumulation and improves process performance of Escherichia coli for recombinant protein production without impairment of growth rate. Metabolic Engineering, 8 (3), 281-290.

Artículo

137 - Lagunas-Munoz,V.H., Cabrera-Valladares,N., Bolivar,F., Gosset,G., Martinez,A. (2006). Optimum melanin production using recombinant Escherichia coli. Journal of Applied Microbiology, 101 (5), 1002-1008.

Artículo

138 - Lara,A.R., Leal,L., FLORES,N., Gosset,G., Bolivar,F., Ramirez,O.T. (2006). Transcriptional and metabolic response of recombinant Escherichia coli to spatial dissolved oxygen tension gradients simulated in a scale-down system. Biotechnology and Bioengineering, 93 (2), 372-385.

Artículo

139 - Lara,A.R., Vazquez-Limon,C., Gosset,G., Bolivar,F., Lopez-Mungua,A., Ramirez,O.T. (2006). Engineering Escherichia coli to improve culture performance and reduce formation of by-products during recombinant protein production under transient intermittent anaerobic conditions. Biotechnology and Bioengineering, 94 (6), 1164-1175.

Artículo

140 - FLORES,N., Flores,S., Escalante,A., de Anda,R., Leal,L., Malpica,R., Georgellis,D., Gosset,G., Bolivar,F. (2005). Adaptation for fast growth on glucose by differential expression of central carbon metabolism and gal regulon genes in an Escherichia coli strain lacking the phosphoenolpyruvate:carbohydrate phosphotransferase system. Metabolic Engineering, 7 (2), 70-87.

Artículo

141 - Flores,S., FLORES,N., de Anda,R., Gonzalez,A., Escalante,A., Sigala,J.C., Gosset,G., Bolivar,F. (2005). Nutrient-Scavenging Stress Response in an Escherichia coli Strain Lacking the Phosphoenolpyruvate:Carbohydrate Phosphotransferase System, as Explored by Gene Expression Profile Analysis. Journal of Molecular Microbiology and Biotechnology, 10 (1), 51-63.

Revisión

142 - Gosset,G. (2005). Improvement of Escherichia coli production strains by modification of the phosphoenolpyruvate:sugar phosphotransferase system. Microbial Cell Factories, 4 (1), 14.

Artículo

143 - Sandoval-Basurto,E.A., Gosset,G., Bolivar,F., Ramirez,O.T. (2005). Culture of Escherichia coli under dissolved oxygen gradients simulated in a two-compartment scale-down system: Metabolic response and production of recombinant protein. Biotechnology and Bioengineering, 89 (4), 453-463.

Artículo

144 - Zhang,Z., Gosset,G., Barabote,R., Gonzalez,C.S., Cuevas,W.A., Saier,M.H.,Jr. (2005). Functional Interactions between the Carbon and Iron Utilization Regulators, Crp and Fur, in Escherichia coli. Journal of Bacteriology, 187 (3), 980-990.

Artículo

145 - Baez-Viveros,J.L., Osuna,J., Hernandez-Chavez,G., Soberon,X., Bolivar,F., Gosset,G. (2004). Metabolic engineering and protein directed evolution increase the yield of L-phenylalanine synthesized from glucose in Escherichia coli. Biotechnology and Bioengineering, 87 (4), 516-524.

Artículo

146 - Escalante,A., Rodriguez,M.E., Martinez,A., Lopez-Munguia,A., Bolivar,F., Gosset,G. (2004). Characterization of bacterial diversity in Pulque, a traditional Mexican alcoholic fermented beverage, as determined by 16S rDNA analysis. Fems Microbiology Letters, 235 (2), 273-279.

Artículo

147 - FLORES,N., de Anda,R., Flores,S., Escalante,A., Hernandez,G., Martinez,A., Ramirez,O.T., Gosset,G., Bolivar,F. (2004). Role of Pyruvate Oxidase in Escherichia coli Strains Lacking the Phosphoenolpyruvate:Carbohydrate Phosphotransferase System. Journal of Molecular Microbiology and Biotechnology, 8 (4), 209-221.

Artículo

148 - Flores,S., Anda-Herrera,R., Gosset,G., Bolivar,F.G. (2004). Growth-rate recovery of Escherichia coli cultures carrying a multicopy plasmid, by engineering of the pentose-phosphate pathway. Biotechnology and Bioengineering, 87 (4), 485-494.

Artículo

149 - Garay-Arroyo,A., Covarrubias,A.A., Clark,I., Nino,I., Gosset,G., Martinez,A. (2004). Response to different environmental stress conditions of industrial and laboratory Saccharomyces cerevisiae strains. Applied Microbiology and Biotechnology, 63 (6), 734-741.

Artículo

150 - Gosset,G., Zhang,Z., Nayyar,S., Cuevas,W.A., Saier,M.H.,Jr. (2004). Transcriptome Analysis of Crp-Dependent Catabolite Control of Gene Expression in Escherichia coli. Journal of Bacteriology, 186 (11), 3516-3524.

Artículo

151 - Hernandez-Montalvo,V., Martinez,A., Bolivar,F., Valle,F., Gosset,G. (2003). Expression of galP and glk in a Escherichia coli PTS mutant restores glucose transport and increases glycolytic flux to fermentation products. Biotechnology and Bioengineering, 83 (6), 687-694.

Artículo

152 - Flores,S., Gosset,G., FLORES,N., de Graaf,A.A., Bolivar,F. (2002). Analysis of carbon metabolism in Escherichia coli strains with an inactive phosphotransferase system by 13C labelling and NMR spectroscopy. Metabolic Engineering, 4 (2), 124-137.

Artículo

153 - Baez,J.L., Bolivar,F., Gosset,G. (2001). Determination of 3-deoxy-D-arabino-heptulosonate 7-phosphate productivity and yield from glucose in Escherichia coli devoid of the glucose phosphotransferase transport system. Biotechnology and Bioengineering, 73 (6), 530-535.

Revisión

154 - Balbas,P., Gosset,G. (2001). Chromosomal editing in Escherichia coli. Vectors for DNA integration and excision. Molecular Biotechnology, 19 (1), 1-12.

Artículo

155 - Gosset,G., Bonner,C.A., Jensen,R.A. (2001). Microbial Origin of Plant-Type 2-Keto-3-Deoxy-D-arabino-Heptulosonate 7-Phosphate Synthases, Exemplified by the Chorismate- and Tryptophan-Regulated Enzyme from Xanthomonas campestris. Journal of Bacteriology, 183 (13), 4061-4070.

Artículo

156 - Hernandez-Montalvo,V., Valle,F., Bolivar,F., Gosset,G. (2001). Characterization of sugar mixtures utilization by an Escherichia coli mutant devoid of the phosphotransferase system. Applied Microbiology and Biotechnology, 57 (1-2), 186-191.

Artículo

157 - Le Borgne,S., Palmeros,B., Bolivar,F., Gosset,G. (2001). Improvement of the pBRINT-Ts plasmid family to obtain marker-free chromosomal insertion of cloned DNA in E. coli. Biotechniques, 30 (2), 252-256.

Artículo

158 - Cruz,N., Le Borgne,S., Hernandez-Chavez,G., Gosset,G., Valle,F., Bolivar,F. (2000). Engineering the Escherichia coli outer membrane protein OmpC for metal bioadsorption. Biotechnology Letters, 22 (7), 623-629.

Artículo

159 - Palmeros,B., Wild,J., Szybalski,W., Le Borgne,S., Hernandez-Chavez,G., Gosset,G., Valle,F., Bolivar,F. (2000). A family of removable cassettes designed to obtain antibiotic-resistance-free genomic modifications of Escherichia coli and other bacteria. Gene, 247 (1-2), 255-264.

Artículo

160 - Le Borgne,S., Palmeros,B., Valle,F., Bolivar,F., Gosset,G. (1998). pBRINT-Ts: a plasmid family with a temperature-sensitive replicon, designed for chromosomal integration into the lacZ gene of Escherichia coli. Gene, 223 (1-2), 213-219.

Artículo

161 - Gosset,G., Yong-Xiao,J., Berry,A. (1996). A direct comparison of approaches for increasing carbon flow to aromatic biosynthesis in Escherichia coli. Journal of Industrial Microbiology, 17 (1), 47-52.

Artículo

162 - Olmos,J., Cruz,N., Sanchez,M., Lopez,M., Balbas,P., Gosset,G., Valle,F., Bolivar,F. (1994). Production in Escherichia coli of a rat chimeric proinsulin polypeptide carrying human A and B chains and its preparative chromatography. Journal of Biotechnology, 38 (1), 89-96.

Artículo

163 - Pfister,C.U., Duval,M., Godbillon,J., Gosset,G., Gygax,D., Marfil,F., Sioufi,A., Winkler,B. (1994). Development, application and comparison of an enzyme immunoassay and a high-performance liquid chromatography method for the determination of the aromatase inhibitor CGS 20,267 in biological fluids. Journal of Pharmaceutical Sciences, 83 (4), 520-524. *

Artículo

164 - Gosset,G., de Anda,R., Cruz,N., Martinez,A., Quintero,R., Bolivar,F. (1993). Recombinant protein production in cultures of an Escherichia coli trp- strain. Applied Microbiology and Biotechnology, 39 (4-5), 541-546.

Artículo

165 - Cruz,N., Lopez,M., Estrada,G., Alvarado,X., de Anda,R., Balbas,P., Gosset,G., Bolivar,F. (1992). Preparative isolation of recombinant human insulin-A chain by ion exchange chromatography. Journal Of Liquid Chromatography, 15 (13), 2311-2324.

Artículo

166 - Cruz,N., Antonio,S., de Anda,R., Gosset,G., Bolivar,F. (1990). Preparative isolation by high performance liquid chromatography of human insulin B chain produced in Escherichia coli. Journal Of Liquid Chromatography, 13 (8), 1517-1528.

Artículo

167 - Gosset,G., Merino,E., Recillas,F., Oliver,G., Becerril,B., Bolivar,F. (1989). Amino acid sequence analysis of the glutamate synthase enzyme from Escherichia coli K-12. Protein sequences & data analysis, 2 (1), 9-16.

Artículo

168 - Puente,J.L., Alvarez-Scherer,V., Gosset,G., Calva,E. (1989). Comparative analysis of the Salmonella typhi and Escherichia coli ompC genes. Gene, 83 (2), 197-206.

Artículo

169 - Oliver,G., Gosset,G., Sanchez-Pescador,R., Lozoya,E., Ku,L.M., FLORES,N., Becerril,B., Valle,F., Bolivar,F. (1987). Determination of the nucleotide sequence for the glutamate synthase structural genes of Escherichia coli K-12. Gene, 60 (1), 1-11.

Artículo

170 - Valle,F., Gosset,G., Tenorio,B., Oliver,G., Bolivar,F. (1986). Characterization of the regulatory region of the Escherichia coli penicillin acylase structural gene. Gene, 50 (1-3), 119-122.

Artículo

171 - Oliver,G., Valle,F., Rosetti,F., Gomez-Pedrozo,M., Santamaria,P., Gosset,G., Bolivar,F. (1985). A common precursor for the two subunits of the penicillin acylase from Escherichia coli ATCC11105. Gene, 40 (1), 9-14.

Ver publicaciones anteriores

Capítulos

Capítulo internacional

172 - Escalante,A., Martinez,A., Bolivar,F., Gosset,G. (2023). Metabolic engineering of the shikimic acid pathway in Escherichia coli for production of derived aromatic compounds. Handbook of Biorefinery Research and Technology. 1-27, Dordrecht: Springer.

Capítulo internacional

173 - Martinez,L.M., Cisneros-Martinez,A.M., Hernandez-Chavez,G., Martinez,A., Gosset,G. (2023). Biotechnological Production of Melanins with Recombinant Microorganisms. Melanins: Functions, Biotechnological Production, and Applications. 67-90, Cham: Springer.

Nacional

174 - Gosset-Lagarda,G. (2018). Generación de una cepa de Escherichia coli para la producción de L-tirosina. Problemas de ingeniería biológica. 387-394, Mexico: Universidad Autónoma Metropolitana, Unidad Cuajimalpa.

Internacional

175 - Gosset, G. (2017). Biotechnological Production of Melanins with Microorganisms. Bio-pigmentation and Biotechnological Implementations. 161-171, Hoboken,N.J..

Internacional

176 - Martinez, A., Rodriguez-Alegria, M., Fernandes, M. C., Gosset, G., Vargas-Tah, A. (2017). Metabolic Engineering of Escherichia coli for Lactic Acid Production from Renewable Resources. Engineering of Microorganisms for the Production of Chemicals and Biofuels from Renewable Resources. 125-145, Cham.

Divulgación

177 - Escalante-Lozada,A., Giles-Gomez,M., Gosset-Lagarda,G. (2014). El pulque, una bebida histórica con importantes implicaciones biotecnológicas. Un Mundo de Bacterias . 91-95.

Internacional

178 - Orencio-Trejo,M., Utrilla,J., Fernandez-Sandoval,M.T., Huerta-Beristain,G., Gosset,G., Martinez,A. (2010). Engineering the Escherichia coli Fermentative Metabolism. Biosystems Engineering II. Advances in Biochemical Engineering/Biotechnology, 71-107, 121.

Internacional

179 - Escalante,A., Martinez,A., Rivera,M., Gosset,G. (2009). Solute transport processes inside the cell. Metabolic Pathway Engineering Handbook . 10-20.

Nacional

180 - Martinez-Jimenez,A., Gosset-Lagarda,G. (2008). Ingeniería metabólica de bacterias, cap 32. Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario. 373-384, Mexico, D.F..

Internacional

181 - Chavez-Bejar,M., Martinez,A., Bolivar,F., Gosset,G. (2005). Metabolic pathway engineering for microbial production of aromatic amino acids. Research Advances in Food Science. 11-20, Kerala: Research Signpost.

Nacional

182 - Gosset,G., Bolivar,F. (2004). Ingenieria celular microbiana. Fundamentos y casos exitosos de la biotecnologia moderna. 219-247, Mexico. *

Internacional

183 - Le Borgne,S., Bolivar,F., Gosset,G. (2004). Plasmid Vectors for Marker-Free Chromosomal Insertion of Genetic Material in Escherichia coli. Recombinant gene expression : reviews and protocols. Methods in molecular biology (Clifton, N.J.), 135-144.

Nacional

184 - Gosset,G., Bolivar,F. (2003). Ingeniería celular en microorganismos. Fronteras de la Biología en los Inicios del Siglo XXI. Módulo VII. 5-34, Mexico,D.F:.

Internacional

185 - LaDuca,R.J., Berry,A., Chotani,G., Dodge,T., Gosset,G., Valle,F., Liao,J., Xiao,J., Power,S. (1999). Metabolic Pathway Engineering of Aromatic Compounds. Manual of industrial microbiology and biotechnology. 605-615, 2, Washington, D.C.

Ver publicaciones anteriores

Libros

Internacional

186 - Gosset,G. (2023). Melanins: Functions, Biotechnological Production, and Applications. VII, 146, Cham: Springer.

Internacional

187 - Lara,A.R., Gosset,G. (2020). Minimal Cells: Design, Construction, Biotechnological Applications. Cham: Springer.

Internacional

188 - Gosset, G. (2017). Engineering of Microorganisms for the Production of Chemicals and Biofuels from Renewable Resources. Cham: Springer.

Otras publicaciones

Preprint

189 - Martinez-Alvarez,J.A., Bouchat,R., Gallet de St Aurin,T., Martinez,L.M., Caspeta,L., Telek,S., Zicler,A., Gosset,G., Delvigne,F. (2024). Automated adjustment of metabolic niches enables the control of natural and engineered microbial co-cultures. bioRxiv, Preprint posted May 14.

Preprint

190 - Pohlen,L., Garcia,E., Martinez,L.M., FLORES,N., Buchs,J., Gosset,G., Lara,A.R. (2024). Sigma factors as potential targets to enhance recombinant protein expression. bioRxiv, Preprint posted November 12.

Nacional

191 - Echanove-Cuevas,D.A., Gosset-Lagarda,G (2023). Revisión de los factores sigma en Escherichia coli y su potencial como dianas para el mejoramiento de producción de proteínas recombinantes. Biotecnologia, 27 (2), 29-48.

nacional divulgación

192 - Martinez,L.M., Martinez,A., Gosset,G. (2021). El enorme potencial de las melaninas como biomateriales, en salud y ambiente. Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 26, 3-7.

nacional divulgacion

193 - Sierra-Ibarra,E., Gosset-Lagarda,G, Martinez-Jimenez,A. (2021). Las biorrefinerías son plataformas sustentables y más limpias. Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 27, 8-14.

Nacional divulgación

194 - Zamudio,G., Gosset,G., Sabido-Ramos,A. (2021). Bioadhesivos: La transición hacia los compuestos bio-basados. BioTecnologia. Sociedad Mexicana de Biotecnologia y Bioingenieria, 25 (1), 31-43.

Nacional divulgacion

195 - Velazquez,D., Gosset,G., Lara,A.R. (2020). Ingeniería Celular como una Alternativa al Cultivo por lote Alimentado para la Producción de Proteínas Recombinantes. BioTecnologia. Sociedad Mexicana de Biotecnologia y Bioingenieria, 24 (1), 30-55.

Divulgación

196 - Gosset,G. (2018). Los microbios como biofábricas. Selecciones, Marzo, 78-86.

Divulgación

197 - Gosset, G. (2017). Los microbios como biofábricas. Ciencia, Revista de la Academia Mexicana de Ciencia, 68 (2), 44-49.

Divulgación

198 - Cortes-Tolalpa,L., Carmona,S.B., Cervantes-Salinas,A., Garcia,M.A., Gosset,G., Escalante,A., Bolivar,F. (2011). Ingeniería de vías metabólicas en Escherichia coli para la producción de Shikimato como precursos para la síntesis de compuestos antivirales contra influenza. BioTecnologia. Sociedad Mexicana de Biotecnologia y Bioingenieria, 15 (1), 30-47.

Divulgación

199 - Sabido,A., Martinez,A., Bolivar,F., Gosset,G. (2011). Generación de un Sistema para la Integración y Expresión de Genes en el Cromosoma de Escherichia coli. BioTecnologia. Sociedad Mexicana de Biotecnologia y Bioingenieria, 15 (3), 35-49.

Nacional

200 - Escalante,A., Valdivia,A., Gosset,G., Bolivar,F. (2009). Ingeniería de Vías Metabólicas en Escherichia Coli Pts- para la Obtención de Cepas Sobreproductoras de Shikimato. Mensaje Bioquimico, 33, 171-180.

Divulgación

201 - Gosset-Lagarda,G (2009). La melanina: producción biotecnológica y aplicaciones. Hypatia, 29.

Editorial Material

202 - Gosset,G. (2008). Microbial production of industrial chemicals. Introduction. Journal of Molecular Microbiology and Biotechnology, 15 (1), 5-7.

Nacional

203 - Romero,S., Orencio,M., Martinez,A., Gosset,G. (2008). Compuestos aromáticos e ingeniería metabólica en bacterias. Ciencia y desarrollo, 34 (225), 8-13.

Nacional

204 - Baez-Viveros,J.L., Osuna,J., Hernandez-Chavez,G., Soberon,X., Bolivar,F., Gosset,G. (2006). Metabolic via engineering for the production of aromatic substances in Escherichia coli. Revista Latinoamericana de Microbiologia, 48 (2), 92.

Nacional

205 - Lagarda,G.G. (2006). [Industrial microbiology]. Revista Latinoamericana de Microbiologia, 48 (2), 91-98. *

Divulgación

206 - Martinez,A., Rodriguez,M.E., Lopez-Munguia,A., Gosset,G. (2006). ¿Etanol carburante a base de bagazo de caña?. Claridades Agropecuarias, 155, 22-25.

Nacional

207 - Escalante-Lozada,A, Gosset-Lagarda,G, Martinez-Jimenez,A., Bolivar-Zapata,F (2004). Soil bacterial diversity: Microbial culture-independent methods of study and biotechnological implications. Agrociencia, 38 (6), 583-592.

Divulgación

208 - Martinez Jimenez,A., Bolivar-Zapata, F, Gosset Lagarda,G. (2002). Biotecnologia energetica sustentable: etanol carburante para el transporte. Revista Universidad de Mexico, 617.

Ver publicaciones anteriores

Tesis

209 - Gosset Lagarda, Guillermo (1993). Insulina humana : produccion por tecnicas de DNA recombinante . Instituto de Biotecnologia, Doctorado en Biotecnologia, UNAM.

Asesor: Bolivar Zapata, Francisco

210 - Gosset Lagarda, Guillermo (1988). Caracterizacion de los genes que codifican para la enzima glutamato Escherichia coli K12 . Centro de Investigacion sobre Ingenieria Genetica y Biotecnologia, Maestria en Investigacion Biomedica Basica, UNAM.

Asesor: Bolivar Zapata, Francisco

211 - Gosset Lagarda, Guillermo (1986). Aislamiento y secuencia nucleotidica de la region reguladora del gene estructural de la enzima penicilino amidasa de E. Coli . Escuela de Biologia, Licenciatura en Biología, Universidad Autonoma de Guadalajara. *

Asesor: Nova Ojeda, Angel, Valle Baheza, Fernando

2025

Artículo

212 - Martinez,J.A., Bouchat,R., Gallet de St Aurin,T., Martinez,L.M., Caspeta,L., Telek,S., Zicler,A., Gosset,G., Delvigne,F.. Automated adjustment of metabolic niches enables the control of natural and engineered microbial co-cultures. Trends in Biotechnology, 43 (5), 1116-1139.

Artículo

213 - Molina-Vazquez,E.R., Caspeta,L., Gosset,G., Martinez,A.. Tailoring Escherichia coli BL21 (DE3) for preferential xylose utilization via metabolic and regulatory engineering. Applied Microbiology and Biotechnology, 109 (1), 54.

Artículo

214 - Perez-Morales,G., Martinez-Conde,K.V., Caspeta,L., Merino,E., Cevallos,M.A., Gosset,G., Martinez,A.. Thermally adapted Escherichia coli keeps transcriptomic response during temperature upshift exposure. Applied Microbiology and Biotechnology, 109 (1), 120.

Artículo communication

215 - Pohlen,L., Garcia,E., Martinez,L.M., FLORES,N., Buchs,J., Gosset,G., Lara,A.R.. Sigma factors as potential targets to enhance recombinant protein expression. Biotechnology and Bioengineering, 122 (6), 1598-1607.

Article

216 - Sayago,J., Martinez,L.M., Hernandez,G., Gosset,G.. Biotechnological melanin synthesized from tyrosine vs other precursors significantly affects its electrochemical response. AIP Advances, 15 (1), 015003.

Artículo in press

217 - Vallejo-Giraldo,A., Martinez,L.M., FLORES,N., Hernandez-Chavez,G., Cueto,F., Martinez,A., Corona-Gonzalez,R.I., Gosset,G.. Construction and Characterization of Novel Shuttle Expression Vectors for Actinobacillus succinogenes. Biotechnology and Applied Biochemistry, Feb 17 [Online ahead of print].

Artículo

218 - Varela-Perez,N.M., Vallejo-Giraldo,A., Fragoso-Jimenez,J.C., Martinez,L.M., Hernandez-Chavez,G., Gutierrez-Rios,R.M., Martinez,A., Marcellin,E., Vieille,C., Gosset,G.. Insights into lactose catabolism and its regulation in Actinobacillus succinogenes. Journal of Applied Microbiology, 136 (6), lxaf134.

2024

Artículo

219 - de la Cruz,M., Kunert,F., Taymaz-Nikerel,H., Sigala,J.C., Gosset,G., Buchs,J., Lara,A.R.. Increasing the Pentose Phosphate Pathway Flux to Improve Plasmid DNA Production in Engineered E. coli. Microorganisms, 12 (1), 150.

Artículo

220 - Escalante,A., Astudillo,F., Larios,V., FLORES,N., Gosset,G., Bolivar,F.. The complete genome of Escherichia coli JM101 assembled with a combination of Nanopore and Illumina platforms. Microbiology Resource Announcements, 13 (2), e0097323.

Articulo

221 - Lara,A.R., Kunert,F., Vandenbroucke,V., Taymaz-Nikerel,H., Martinez,L.M., Sigala,J.C., Delvigne,F., Gosset,G., Buchs,J.. Transport-controlled growth decoupling for self-induced protein expression with a glycerol repressible genetic circuit. Biotechnology and Bioengineering, 121 (6), 1789-1802.

Artículo

222 - Lara,A.R., Utrilla,J., Martinez,L.M., Krausch,N., Kaspersetz,L., Hidalgo,D., Cruz-Bournazou,N., Neubauer,P., Sigala,J.C., Gosset,G., Buchs,J.. Recombinant protein expression in proteome-reduced cells under aerobic and oxygen-limited regimes. Biotechnology and Bioengineering, 121 (4), 1216-1230.

Artículo

223 - Perez-Morales,G., Caspeta,L., Merino,E., Cevallos,M.A., Gosset,G., Martinez,A.. Simultaneous saccharification and fermentation for D-lactic acid production using a metabolically engineered Escherichia coli adapted to high temperature. Biotechnology for Biofuels and Bioproducts, 17 (1), 132.

Preprint

224 - Martinez-Alvarez,J.A., Bouchat,R., Gallet de St Aurin,T., Martinez,L.M., Caspeta,L., Telek,S., Zicler,A., Gosset,G., Delvigne,F.. Automated adjustment of metabolic niches enables the control of natural and engineered microbial co-cultures. bioRxiv, Preprint posted May 14.

Preprint

225 - Pohlen,L., Garcia,E., Martinez,L.M., FLORES,N., Buchs,J., Gosset,G., Lara,A.R.. Sigma factors as potential targets to enhance recombinant protein expression. bioRxiv, Preprint posted November 12.

2023

Artículo

226 - Alcala-Alcala,S., Casarrubias-Anacleto,J.E., Mondragon-Guillen,M., Tavira-Montalvan,C.A., Bonilla-Hernandez,M., Gomez-Galicia,D.L., Gosset,G., Meneses-Acosta,A.. Melanin Nanoparticles Obtained from Preformed Recombinant Melanin by Bottom-Up and Top-Down Approaches. Polymers (Basel), 15 (10), 2381.

Revision

227 - Carreon-Rodriguez,O.E., Gosset,G., Escalante,A., Bolivar,F.. Glucose Transport in Escherichia coli: From Basics to Transport Engineering. Microorganisms, 11 (6), 1588.

Artículo

228 - Krausch,N., Kaspersetz,L., Gaytan-Castro,R.D., Schermeyer,M.T., Lara,A.R., Gosset,G., Cruz Bournazou,M.N., Neubauer,P.. Model-Based Characterization of E. coli Strains with Impaired Glucose Uptake. Bioengineering (Basel), 10 (7).

Capítulo internacional

229 - Escalante,A., Martinez,A., Bolivar,F., Gosset,G.. Metabolic engineering of the shikimic acid pathway in Escherichia coli for production of derived aromatic compounds. Handbook of Biorefinery Research and Technology. 1-27, Dordrecht: Springer.

Capítulo internacional

230 - Martinez,L.M., Cisneros-Martinez,A.M., Hernandez-Chavez,G., Martinez,A., Gosset,G.. Biotechnological Production of Melanins with Recombinant Microorganisms. Melanins: Functions, Biotechnological Production, and Applications. 67-90, Cham: Springer.

Internacional

231 - Gosset,G.. Melanins: Functions, Biotechnological Production, and Applications. VII, 146, Cham: Springer.

Nacional

232 - Echanove-Cuevas,D.A., Gosset-Lagarda,G. Revisión de los factores sigma en Escherichia coli y su potencial como dianas para el mejoramiento de producción de proteínas recombinantes. Biotecnologia, 27 (2), 29-48.

2022

Artículo

233 - Fragoso-Jimenez,J.C., Gutierrez-Rios,R.M., FLORES,N., Martinez,A., Lara,A.R., Delvigne,F., Gosset,G.. Glucose consumption rate-dependent transcriptome profiling of Escherichia coli provides insight on performance as microbial factories. Microbial Cell Factories, 21 (1), 189.

Artículo

234 - Rodriguez-Ochoa,J.I., Fragoso-Jimenez,J.C., FLORES,N., Martinez,L.M., Bolivar,F., Martinez,A., Gosset,G.. Global transcriptomic response of Escherichia coli to p-coumaric acid. Microbial Cell Factories, 21 (1), 148.

Artículo

235 - Velazquez,D., Sigala,J.C., Martinez,L.M., Gaytan,P., Gosset,G., Lara,A.R.. Glucose transport engineering allows mimicking fed-batch performance in batch mode and selection of superior producer strains. Microbial Cell Factories, 21 (1), 183.

2021

Revisión

236 - Escalante,A., Mendoza-Flores,R., Gosset,G., Bolivar,F.. The aminoshikimic acid pathway in bacteria as source of precursors for the synthesis of antibacterial and antiviral compounds. Journal of Industrial Microbiology & Biotechnology, 48 (9-10), kuab053.

Artículo

237 - Sierra-Ibarra,E., Leal-Reyes,L.J., Huerta-Beristain,G., Hernandez-Orihuela,A.L., Gosset,G., Martinez-Antonio,A., Martinez,A.. Limited oxygen conditions as an approach to scale-up and improve D and L-lactic acid production in mineral media and avocado seed hydrolysates with metabolically engineered Escherichia coli. Bioprocess and Biosystems Engineering, 44, 379-389.

nacional divulgación

238 - Martinez,L.M., Martinez,A., Gosset,G.. El enorme potencial de las melaninas como biomateriales, en salud y ambiente. Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 26, 3-7.

nacional divulgacion

239 - Sierra-Ibarra,E., Gosset-Lagarda,G, Martinez-Jimenez,A.. Las biorrefinerías son plataformas sustentables y más limpias. Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 27, 8-14.

Nacional divulgación

240 - Zamudio,G., Gosset,G., Sabido-Ramos,A.. Bioadhesivos: La transición hacia los compuestos bio-basados. BioTecnologia. Sociedad Mexicana de Biotecnologia y Bioingenieria, 25 (1), 31-43.

2020

Artículo

241 - Carmona,S.B., FLORES,N., Martinez-Romero,E., Gosset,G., Bolivar,F., Escalante,A.. Evolution of an Escherichia coli PTS(-) strain: a study of reproducibility and dynamics of an adaptive evolutive process. Applied Microbiology and Biotechnology, 104, 9309?9325.

Internacional

242 - Lara,A.R., Gosset,G.. Minimal Cells: Design, Construction, Biotechnological Applications. Cham: Springer.

Nacional divulgacion

243 - Velazquez,D., Gosset,G., Lara,A.R.. Ingeniería Celular como una Alternativa al Cultivo por lote Alimentado para la Producción de Proteínas Recombinantes. BioTecnologia. Sociedad Mexicana de Biotecnologia y Bioingenieria, 24 (1), 30-55.

2019

Artículo

244 - Fernandez-Sandoval,M.T., Galindez-Mayer,J., Bolivar,F., Gosset,G., Ramirez,O.T., Martinez,A.. Xylose-glucose co-fermentation to ethanol by Escherichia coli strain MS04 using single- and two-stage continuous cultures under micro-aerated conditions. Microbial Cell Factories, 18 (1), 145.

Artículo

245 - Fragoso-Jimenez,J.C., Baert,J., Nguyen,T.M., Liu,W., Sassi,H., Goormaghtigh,F., Van Melderen L., Gaytan,P., Hernandez-Chavez,G., Martinez,A., Delvigne,F., Gosset,G.. Growth-dependent recombinant product formation kinetics can be reproduced through engineering of glucose transport and is prone to phenotypic heterogeneity. Microbial Cell Factories, 18 (1), 26.

Revisión

246 - Hernandez-Chavez,G., Martinez,A., Gosset,G.. Metabolic engineering strategies for caffeic acid production in Escherichia coli. Electronic Journal of Biotechnology, 38, 19-26.

Revisión

247 - Martinez,L.M., Martinez,A., Gosset,G.. Production of Melanins With Recombinant Microorganisms. Frontiers in Bioengineering and Biotechnology, 7, 285.

Artículo

248 - Salcedo-Vite,K., Sigala,J.C., Segura,D., Gosset,G., Martinez,A.. Acinetobacter baylyi ADP1 growth performance and lipid accumulation on different carbon sources. Applied Microbiology and Biotechnology, 103 (15), 6217-6229.

Artículo

249 - Sassi,H., Nguyen,T.M., Telek,S., Gosset,G., Grunberger,A., Delvigne,F.. Segregostat: a novel concept to control phenotypic diversification dynamics on the example of Gram-negative bacteria. Microbial Biotechnology, 12 (5), 1064-1075.

2018

Artículo

250 - Martinez,J.A., Rodriguez,A., Moreno,F., FLORES,N., Lara,A.R., Ramirez,O.T., Gosset,G., Bolivar,F.. Metabolic modeling and response surface analysis of an Escherichia coli strain engineered for shikimic acid production. BMC Systems Biology, 12 (1), 102.

Artículo

251 - Salas-Navarrete, C., Hernandez-Chavez, G., Flores, N., Martinez, L.M., Martinez, A., Bolivar, F., Barona-Gomez, F., Gosset, G.. Increasing pinosylvin production in Escherichia coli by reducing the expression level of the gene fabI-encoded enoyl-acyl carrier protein reductase. Electronic Journal of Biotechnology, 33, 11-16.

Nacional

252 - Gosset-Lagarda,G.. Generación de una cepa de Escherichia coli para la producción de L-tirosina. Problemas de ingeniería biológica. 387-394, Mexico: Universidad Autónoma Metropolitana, Unidad Cuajimalpa.

Divulgación

253 - Gosset,G.. Los microbios como biofábricas. Selecciones, Marzo, 78-86.

2017

Artículo

254 - Fernandez-Sandoval, M.T., Galindez-Mayer, J., Moss-Acosta, C.L., Gosset, G., Martinez, A.. Volumetric oxygen transfer coefficient as a means of improving volumetric ethanol productivity and a criterion for scaling up ethanol production with Escherichia coli. Journal of Chemical Technology and Biotechnology, 92 (5), 981-989.

Artículo

255 - Garcia, S., Flores, N., de Anda, R., Hernandez, G., Gosset, G., Bolivar, F., Escalante, A.. The Role of the ydiB Gene, Which Encodes Quinate/Shikimate Dehydrogenase, in the Production of Quinic, Dehydroshikimic and Shikimic Acids in a PTS- Strain of Escherichia coli. Journal of Molecular Microbiology and Biotechnology, 27 (1), 11-21.

Artículo

256 - Huerta-Beristain, G., Cabrera-Ruiz, R., Hernandez-Chavez, G., Bolivar, F., Gosset, G., Martinez, A.. Metabolic engineering and adaptive evolution of Escherichia coli KO11 for ethanol production through the Entner-Doudoroff and the pentose phosphate pathways. Journal of Chemical Technology and Biotechnology, 92 (5), 990-996.

Artículo

257 - Rodriguez, A., Martinez, J.A., Millard, P., Gosset, G., Portais, J.C., Letisse, F., Bolivar, F.. Plasmid-encoded biosynthetic genes alleviate metabolic disadvantages while increasing glucose conversion to shikimate in an engineered Escherichia coli strain. Biotechnology and Bioengineering, 114 (6), 1319-1330.

Internacional

258 - Gosset, G.. Biotechnological Production of Melanins with Microorganisms. Bio-pigmentation and Biotechnological Implementations. 161-171, Hoboken,N.J..

Internacional

259 - Martinez, A., Rodriguez-Alegria, M., Fernandes, M. C., Gosset, G., Vargas-Tah, A.. Metabolic Engineering of Escherichia coli for Lactic Acid Production from Renewable Resources. Engineering of Microorganisms for the Production of Chemicals and Biofuels from Renewable Resources. 125-145, Cham.

Internacional

260 - Gosset, G.. Engineering of Microorganisms for the Production of Chemicals and Biofuels from Renewable Resources. Cham: Springer.

Divulgación

261 - Gosset, G.. Los microbios como biofábricas. Ciencia, Revista de la Academia Mexicana de Ciencia, 68 (2), 44-49.

2016

Artículo

262 - Baert,J., Delepierre,A., Telek,S., Fickers,P., Toye,D., Delamotte,A., Lara,A.R., Jaen,K.E., Gosset,G., Jensen,P.R., Delvigne,F.. Microbial population heterogeneity versus bioreactor heterogeneity: Evaluation of Redox Sensor Green as an exogenous metabolic biosensor. Engineering in Life Sciences, 16 (7), 643-651.

Artículo

263 - Camacho-Zaragoza,J.M., Hernandez-Chavez,G., Moreno-Avitia,F., Ramirez-Iniguez,R., Martinez,A., Bolivar,F., Gosset,G.. Engineering of a microbial coculture of Escherichia coli strains for the biosynthesis of resveratrol. Microbial Cell Factories, 15 (1), 163.

Artículo

264 - Mejia-Caballero,A., de Anda,R., Hernandez-Chavez,G., Rogg,S., Martinez,A., Bolivar,F., Castano,V.M., Gosset,G.. Biosynthesis of catechol melanin from glycerol employing metabolically engineered Escherichia coli. Microbial Cell Factories, 15 (1), 161.

Artículo

265 - Utrilla,J., Vargas-Tah,A., Trujillo-Martinez,B., Gosset,G., Martinez,A.. Production of d-lactate from sugarcane bagasse and corn stover hydrolysates using metabolic engineered Escherichia coli strains. Bioresource Technology, 220, 208-214.

2015

Revisión

266 - Carmona,S.B., Moreno,F., Bolivar,F., Gosset,G., Escalante,A.. Inactivation of the PTS as a Strategy to Engineer the Production of Aromatic Metabolites in Escherichia coli. Journal of Molecular Microbiology and Biotechnology, 25 (2-3), 195-208.

Artículo

267 - Vargas-Tah,A., Moss-Acosta,C.L., Trujillo-Martinez,B., Tiessen,A., Lozoya-Gloria,E., Orencio-Trejo,M., Gosset,G., Martinez,A.. Non-severe thermochemical hydrolysis of stover from white corn and sequential enzymatic saccharification and fermentation to ethanol. Bioresource Technology, 198, 611-618.

Artículo

268 - Vargas-Tah,A., Gosset,G.. Production of Cinnamic and p-Hydroxycinnamic Acids in Engineered Microbes. Frontiers in Bioengineering and Biotechnology, 3, 116.

Artículo

269 - Vargas-Tah,A., Martinez,L., Hernandez-Chavez,G., Rocha,M., Martinez,A., Bolivar,F., Gosset,G.. Production of cinnamic and p -hydroxycinnamic acid from sugar mixtures with engineered Escherichia coli. Microbial Cell Factories, 14 (1), 185.

2014

Artículo

270 - Balderas-Hernandez,V.E., Trevino-Quintanilla,L.G., Hernandez-Chavez,G., Martinez,A., Bolivar,F., Gosset,G.. Catechol biosynthesis from glucose in Escherichia coli anthranilate-overproducer strains by heterologous expression of anthranilate 1,2-dioxygenase from Pseudomonas aeruginosa PAO1. Microbial Cell Factories, 13 (1), 136.

Artículo

271 - Centeno-Leija,S., Huerta-Beristain,G., Giles-Gomez,M., Bolivar,F., Gosset,G., Martinez,A.. Improving poly-3-hydroxybutyrate production in Escherichia coli by combining the increase in the NADPH pool and acetyl-CoA availability. Antonie Van Leeuwenhoek, 105 (4), 687-696.

Artículo

272 - Cortes-Tolalpa,L., Gutierrez-Rios,R.M., Martinez,L.M., de Anda,R., Gosset,G., Bolivar,F., Escalante,A.. Global transcriptomic analysis of an engineered Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system during shikimic acid production in rich culture medium. Microbial Cell Factories, 13 (1), 28.

Artículo

273 - Licona-Cassani,C., Lara,A.R., Cabrera-Valladares,N., Escalante,A., Hernandez-Chavez,G., Martinez,A., Bolivar,F., Gosset,G.. Inactivation of Pyruvate Kinase or the Phosphoenolpyruvate: Sugar Phosphotransferase System Increases Shikimic and Dehydroshikimic Acid Yields from Glucose in Bacillus subtilis. Journal of Molecular Microbiology and Biotechnology, 24 (1), 37-45.

Artículo

274 - Munoz-Gutierrez,I., Moss-Acosta,C., Trujillo-Martinez,B., Gosset,G., Martinez,A.. Ag43-mediated display of a thermostable á-glucosidase in Escherichia coli and its use for simultaneous saccharification and fermentation at high temperatures. Microbial Cell Factories, 13 (1), 106.

Revisión

275 - Rodriguez,A., Martinez,J.A., FLORES,N., Escalante,A., Gosset,G., Bolivar,F.. Engineering Escherichia coli to overproduce aromatic amino acids and derived compounds. Microbial Cell Factories, 13 (1), 126.

Artículo

276 - Ruiz-Villafan,B., Rodriguez-Sanoja,R., Aguilar-Osorio,G., Gosset,G., Sanchez,S.. Glucose kinases from Streptomyces peucetius var. caesius. Applied Microbiology and Biotechnology, 98 (13), 6061-6071.

Artículo

277 - Sabido,A., Sigala,J.C., Hernandez-Chavez,G., FLORES,N., Gosset,G., Bolivar,F.. Physiological and transcriptional characterization of Escherichia coli strains lacking interconversion of phosphoenolpyruvate and pyruvate when glucose and acetate are coutilized. Biotechnology and Bioengineering, 111 (6), 1150-1160.

Artículo

278 - Wunderlich,M., Taymaz-Nikerel,H., Gosset,G., Ramirez,O.T., Lara,A.R.. Effect of growth rate on plasmid DNA production and metabolic performance of engineered Escherichia coli strains. Journal of Bioscience and Bioengineering, 117 (3), 336-342.

Divulgación

279 - Escalante-Lozada,A., Giles-Gomez,M., Gosset-Lagarda,G.. El pulque, una bebida histórica con importantes implicaciones biotecnológicas. Un Mundo de Bacterias . 91-95.

2013

Artículo

280 - Centeno-Leija,S., Utrilla,J., FLORES,N., Rodriguez,A., Gosset,G., Martinez,A.. Metabolic and transcriptional response of Escherichia coli with a NADP-dependent glyceraldehyde 3-phosphate dehydrogenase from Streptococcus mutans. Antonie Van Leeuwenhoek, 104 (6), 913-924.

Artículo

281 - Chavez-Bejar,M.I., Balderas-Hernandez,V.E., Gutierrez-Alejandre,A., Martinez,A., Bolivar,F., Gosset,G.. Metabolic engineering of Escherichia coli to optimize melanin synthesis from glucose. Microbial Cell Factories, 12 (1), 108.

Artículo

282 - Fuentes,L.G., Lara,A.R., Martinez,L.M., Ramirez,O.T., Martinez,A., Bolivar,F., Gosset,G.. Modification of glucose import capacity in Escherichia coli: physiologic consequences and utility for improving DNA vaccine production. Microbial Cell Factories, 12 (1), 42.

Artículo

283 - Rodriguez,A., Martinez,J.A., Baez-Viveros,J.L., FLORES,N., Hernandez-Chavez,G., Ramirez,O.T., Gosset,G., Bolivar,F.. Constitutive expression of selected genes from the pentose phosphate and aromatic pathways increases the shikimic acid yield in high-glucose batch cultures of an Escherichia coli strain lacking PTS and pykF. Microbial Cell Factories, 12 (1), 86.

Artículo

284 - Sabido,A., Martinez,L.M., de Anda,R., Martinez,A., Bolivar,F., Gosset,G.. A novel plasmid vector designed for chromosomal gene integration and expression: Use for developing a genetically stable Escherichia coli melanin production strain. Plasmid, 69 (1), 16-23.

Artículo

285 - Soria,S., de Anda,R., FLORES,N., Romero-Garcia,S., Gosset,G., Bolivar,F., Baez-Viveros,J.L.. New insights on transcriptional responses of genes involved in carbon central metabolism, respiration and fermentation to low ATP levels in Escherichia coli. Journal of Basic Microbiology, 53 (4), 365-380.

2012

Artículo

286 - Aguilar,C., Escalante,A., FLORES,N., de Anda,R., Riveros-McKay,F., Gosset,G., Morett,E., Bolivar,F.. Genetic changes during a laboratory adaptive evolution process that allowed fast growth in glucose to an Escherichia coli strain lacking the major glucose transport system. BMC Genomics, 13 (1), 385.

Artículo

287 - Borja,G.M., Meza-Mora E., Barron,B., Gosset,G., Ramirez,O.T., Lara,A.R.. Engineering Escherichia coli to increase plasmid DNA production in high cell-density cultivations in batch mode. Microbial Cell Factories, 11 (1), 132.

Artículo

288 - Cabrera-Valladares,N., Martinez,L.M., FLORES,N., Hernandez-Chavez,G., Martinez,A., Bolivar,F., Gosset,G.. Physiologic Consequences of Glucose Transport and Phosphoenolpyruvate Node Modifications in Bacillus subtilis 168. Journal of Molecular Microbiology and Biotechnology, 22 (3), 177-197.

Revisión

289 - Chavez-Bejar,M.I., Baez-Viveros,J.L., Martinez,A., Bolivar,F., Gosset,G.. Biotechnological production of l-tyrosine and derived compounds. Process Biochemistry, 47 (7), 1017-1026.

Revisión

290 - Escalante,A., Salinas-Cervantes A., Gosset,G., Bolivar,F.. Current knowledge of the Escherichia coli phosphoenolpyruvate-carbohydrate phosphotransferase system: peculiarities of regulation and impact on growth and product formation. Applied Microbiology and Biotechnology, 94 (6), 1483-1494.

Artículo

291 - Fernandez-Sandoval,M.T., Huerta-Beristain,G., Trujillo-Martinez,B., Bustos,P., Gonzalez,V., Bolivar,F., Gosset,G., Martinez,A.. Laboratory metabolic evolution improves acetate tolerance and growth on acetate of ethanologenic Escherichia coli under non-aerated conditions in glucose-mineral medium. Applied Microbiology and Biotechnology, 96 (5), 1291-1300.

Artículo

292 - Martinez-Gomez,K., FLORES,N., Castaneda,H.M., Martinez-Batallar,G., Hernandez-Chavez,G., Ramirez,O.T., Gosset,G., Encarnacion,S., Bolivar,F.. New insights into Escherichia coli metabolism: carbon scavenging, acetate metabolism and carbon recycling responses during growth on glycerol. Microbial Cell Factories, 11 (1), 46.

Artículo

293 - Meza,E., Becker,J., Bolivar,F., Gosset,G., Wittmann,C.. Consequences of phosphoenolpyruvate:sugar phosphotranferase system and pyruvate kinase isozymes inactivation in central carbon metabolism flux distribution in Escherichia coli. Microbial Cell Factories, 11 (1), 127.

Artículo

294 - Munoz-Gutierrez,I., Oropeza,R., Gosset,G., Martinez,A.. Cell surface display of a beta-glucosidase employing the type V secretion system on ethanologenic Escherichia coli for the fermentation of cellobiose to ethanol. Journal of Industrial Microbiology & Biotechnology, 39 (8), 1141-1152.

Artículo; Actas Paper

295 - Pablos,T.E., Soto,R., Mora,E.M., Le Borgne,S., Ramirez,O.T., Gosset,G., Lara,A.R.. Enhanced production of plasmid DNA by engineered Escherichia coli strains. Journal of Biotechnology, 158 (4), 211-214.

Artículo

296 - Utrilla,J., Licona-Cassani,C., Marcellin,E., Gosset,G., Nielsen,L.K., Martinez,A.. Engineering and adaptive evolution of Escherichia coli for d-lactate fermentation reveals GatC as a xylose transporter. Metabolic Engineering, 14 (5), 469-476.

2011

Artículo

297 - Balderas-Hernandez,V.E., Hernandez-Montalvo,V., Bolivar,F., Gosset,G., Martinez,A.. Adaptive Evolution of Escherichia coli Inactivated in the Phosphotransferase System Operon Improves Co-utilization of Xylose and Glucose Under Anaerobic Conditions. Applied Biochemistry and Biotechnology, 163 (4), 485-496.

Artículo

298 - Lopes,M.S.G., Gosset,G., Rocha,R.C.S., Gomez,J.G.C., Ferreira da Silva,L.. PHB Biosynthesis in Catabolite Repression Mutant of Burkholderia sacchari. Current Microbiology, 63 (4), 319-326.

Artículo

299 - Munoz,A.J., Hernandez-Chavez,G., de Anda,R., Martinez,A., Bolivar,F., Gosset,G.. Metabolic engineering of Escherichia coli for improving L: -3,4-dihydroxyphenylalanine (L: -DOPA) synthesis from glucose. Journal of Industrial Microbiology & Biotechnology, 38 (11), 1845-1852.

Artículo

300 - Pablos,T.E., Mora,E.M., Le Borgne,S., Ramirez,O.T., Gosset,G., Lara,A.R.. Vitreoscilla hemoglobin expression in engineered Escherichia coli: Improved performance in high cell-density batch cultivations. Biotechnology Journal, 6 (8), 993-1002.

Artículo

301 - Soto,R., Caspeta,L., Barron,B., Gosset,G., Ramirez,O.T., Lara,A.R.. High cell-density cultivation in batch mode for plasmid DNA production by a metabolically engineered E. coli strain with minimized overflow metabolism. Biochemical Engineering Journal, 56 (3), 165-171.

Artículo

302 - Tierrafria,V.H., Ramos-Aboites,H.E., Gosset,G., Barona-Gomez,F.. Disruption of the siderophore-binding desE receptor gene in Streptomyces coelicolor A3(2) results in impaired growth in spite of multiple iron-siderophore transport systems. Microbial Biotechnology, 4 (2), 275-285.

Divulgación

303 - Cortes-Tolalpa,L., Carmona,S.B., Cervantes-Salinas,A., Garcia,M.A., Gosset,G., Escalante,A., Bolivar,F.. Ingeniería de vías metabólicas en Escherichia coli para la producción de Shikimato como precursos para la síntesis de compuestos antivirales contra influenza. BioTecnologia. Sociedad Mexicana de Biotecnologia y Bioingenieria, 15 (1), 30-47.

Divulgación

304 - Sabido,A., Martinez,A., Bolivar,F., Gosset,G.. Generación de un Sistema para la Integración y Expresión de Genes en el Cromosoma de Escherichia coli. BioTecnologia. Sociedad Mexicana de Biotecnologia y Bioingenieria, 15 (3), 35-49.

2010

Artículo

305 - Escalante,A., Calderon,R., Valdivia,A., de Anda,R., Hernandez,G., Ramirez,O.T., Gosset,G., Bolivar,F.. Metabolic engineering for the production of shikimic acid in an evolved Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system. Microbial Cell Factories, 9 (1), 21.

Internacional

306 - Orencio-Trejo,M., Utrilla,J., Fernandez-Sandoval,M.T., Huerta-Beristain,G., Gosset,G., Martinez,A.. Engineering the Escherichia coli Fermentative Metabolism. Biosystems Engineering II. Advances in Biochemical Engineering/Biotechnology, 71-107, 121.

2009

Artículo

307 - Balderas-Hernandez,V.E., Sabido-Ramos,A., Silva,P., Cabrera-Valladares,N., Hernandez-Chavez,G., Baez-Viveros,J.L., Martinez,A., Bolivar,F., Gosset,G.. Metabolic engineering for improving anthranilate synthesis from glucose in Escherichia coli. Microbial Cell Factories, 8 (1), 19.

Revisión

308 - Gosset,G.. Production of aromatic compounds in bacteria. Current Opinion in Biotechnology, 20 (6), 651-658.

Artículo

309 - Olvera,L., Mendoza-Vargas,A., FLORES,N., Olvera,M., Sigala,J.C., Gosset,G., Morett,E., Bolivar,F.. Transcription Analysis of Central Metabolism Genes in Escherichia coli. Possible Roles of a38 in Their Expression, as a Response to Carbon Limitation. PLoS ONE, 4 (10), e7466.

Artículo

310 - Romero-Garcia,S., Hernandez-Bustos,C., Merino,E., Gosset,G., Martinez,A.. Homolactic fermentation from glucose and cellobiose using Bacillus subtilis. Microbial Cell Factories, 8 (1), 23.

Artículo

311 - Sigala,J.C., Flores,S., FLORES,N., Aguilar,C., de Anda,R., Gosset,G., Bolivar,F.. Acetate Metabolism in Escherichia coli Strains Lacking Phosphoenolpyruvate: Carbohydrate Phosphotransferase System; Evidence of Carbon Recycling Strategies and Futile Cycles. Journal of Molecular Microbiology and Biotechnology, 16 (3-4), 224-235.

Artículo

312 - Utrilla,J., Gosset,G., Martinez,A.. ATP limitation in a pyruvate formate lyase mutant of Escherichia coli MG1655 increases glycolytic flux to D: -lactate. Journal of Industrial Microbiology & Biotechnology, 36 (8), 1057-1062.

Artículo

313 - Vazquez,C.D., Freyre-Gonzalez,J.A., Gosset,G., Loza,J.A., Gutierrez-Rios,R.M.. Identification of network topological units coordinating the global expression response to glucose in Bacillus subtilis and its comparison to Escherichia coli. BMC Microbiology, 9 (1), 176.

Internacional

314 - Escalante,A., Martinez,A., Rivera,M., Gosset,G.. Solute transport processes inside the cell. Metabolic Pathway Engineering Handbook . 10-20.

Nacional

315 - Escalante,A., Valdivia,A., Gosset,G., Bolivar,F.. Ingeniería de Vías Metabólicas en Escherichia Coli Pts- para la Obtención de Cepas Sobreproductoras de Shikimato. Mensaje Bioquimico, 33, 171-180.

Divulgación

316 - Gosset-Lagarda,G. La melanina: producción biotecnológica y aplicaciones. Hypatia, 29.

2008

Artículo

317 - Chavez-Bejar,M.I., Lara,A.R., Lopez,H., Hernandez-Chavez,G., Martinez,A., Ramirez,O.T., Bolivar,F., Gosset,G.. Metabolic engineering of Escherichia coli for L-tyrosine production by the expression of the genes coding for the chorismate mutase domain from native P-protein and a cyclohexadienyl dehydrogenase from Zymomonas mobilis. Applied and Environmental Microbiology, 74 (10), 3284-3290.

Artículo

318 - Escalante,A., Giles-Gomez,M., Hernandez,G., Cordova-Aguilar,M.S., Lopez-Munguia,A., Gosset,G., Bolivar,F.. Analysis of bacterial community during the fermentation of pulque, a traditional Mexican alcoholic beverage, using a polyphasic approach. International Journal of Food Microbiology, 124 (2), 126-134.

Artículo

319 - FLORES,N., Escalante,A., de Anda,R., Baez-Viveros,J.L., Merino,E., Franco,B., Georgellis,D., Gosset,G., Bolivar,F.. New Insights into the Role of Sigma Factor RpoS as Revealed in Escherichia coli Strains Lacking the Phosphoenolpyruvate:Carbohydrate Phosphotransferase System. Journal of Molecular Microbiology and Biotechnology, 14 (4), 176-192.

Artículo

320 - Huerta-Beristain,G., Utrilla,J., Hernandez-Chavez,G., Bolivar,F., Gosset,G., Martinez,A.. Specific ethanol production rate in ethanologenic Escherichia coli strain KO11 Is limited by pyruvate decarboxylase. Journal of Molecular Microbiology and Biotechnology, 15 (1), 55-64.

Artículo

321 - Lara,A.R., Caspeta,L., Gosset,G., Bolivar,F., Ramirez,O.T.. Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: An alternative to fed-batch cultures. Biotechnology and Bioengineering, 99 (4), 893-901.

Artículo

322 - Martinez,K., de Anda,R., Hernandez,G., Escalante,A., Gosset,G., Ramirez,O.T., Bolivar,F.G.. Coutilization of glucose and glycerol enhances the production of aromatic compounds in an Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system. Microbial Cell Factories, 7 (1), 1.

Artículo

323 - Orencio-Trejo,M., FLORES,N., Escalante,A., Hernandez-Chavez,G., Bolivar,F., Gosset,G., Martinez,A.. Metabolic regulation analysis of an ethanologenic Escherichia coli strain based on RT-PCR and enzymatic activities. Biotechnology for Biofuels, 1 (1), 8.

Nacional

324 - Martinez-Jimenez,A., Gosset-Lagarda,G.. Ingeniería metabólica de bacterias, cap 32. Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario. 373-384, Mexico, D.F..

Editorial Material

325 - Gosset,G.. Microbial production of industrial chemicals. Introduction. Journal of Molecular Microbiology and Biotechnology, 15 (1), 5-7.

Nacional

326 - Romero,S., Orencio,M., Martinez,A., Gosset,G.. Compuestos aromáticos e ingeniería metabólica en bacterias. Ciencia y desarrollo, 34 (225), 8-13.

2007

Artículo

327 - Baez-Viveros,J.L., FLORES,N., Suarez,K., Castillo-Espana,P., Bolivar,F., Gosset,G.. Metabolic transcription analysis of engineered Escherichia coli strains that overproduce L-phenylalanine. Microbial Cell Factories, 6 (1), 30.

Artículo

328 - FLORES,N., Leal,L., Sigala,J.C., de Anda,R., Escalante,A., Martinez,A., Ramirez,O.T., Gosset,G., Bolivar,F.. Growth Recovery on Glucose under Aerobic Conditions of an Escherichia coli Strain Carrying a Phosphoenolpyruvate:Carbohydrate Phosphotransferase System Deletion by Inactivating arcA and Overexpressing the Genes Coding for Glucokinase and Galactose Permease. Journal of Molecular Microbiology and Biotechnology, 13 (1-3), 105-116.

Artículo

329 - Gutierrez-Rios,R.M., Freyre-Gonzalez,J.A., Resendis,O., Collado-Vides,J., Saier,M., Gosset,G.. Identification of regulatory network topological units coordinating the genome-wide transcriptional response to glucose in Escherichia coli. BMC Microbiology, 7 (1), 53.

Artículo

330 - Pinero,S., Rivera,J., Romero,D., Cevallos,M.A., Martinez,A., Bolivar,F., Gosset,G.. Tyrosinase from Rhizobium etli Is Involved in Nodulation Efficiency and Symbiosis-Associated Stress Resistance. Journal of Molecular Microbiology and Biotechnology, 13 (1-3), 35-44.

Artículo

331 - Romero,S., Merino,E., Bolivar,F., Gosset,G., Martinez,A.. Metabolic engineering of Bacillus subtilis for ethanol production: Lactate dehydrogenase plays a key role in the fermentative metabolism. Applied and Environmental Microbiology, 73 (16), 5190-5198.

Artículo

332 - Trevino-Quintanilla,L.G., Escalante,A., Caro,A.D., Martinez,A., Gonzalez,R., Puente,J.L., Bolivar,F., Gosset,G.. The Phosphotransferase System-Dependent Sucrose Utilization Regulon in Enteropathogenic Escherichia coli Strains Is Located in a Variable Chromosomal Region Containing iap Sequences. Journal of Molecular Microbiology and Biotechnology, 13 (1-3), 117-125.

Artículo

333 - Vazquez-Limon,C., Vega-Badillo,J., Martinez,A., Espinosa-Molina,G., Gosset,G., Soberon,X., Lopez-Munguia,A., Osuna,J.. Growth rate of a non-fermentative Escherichia coli strain is influenced by NAD(+) regeneration. Biotechnology Letters, 29 (12), 1857-1863.

2006

Artículo

334 - Cabrera-Valladares,N., Martinez,A., Pinero,S., Lagunas-Munoz,V.H., Tinoco,R., de Anda,R., Vazquez-Duhalt,R., Bolivar,F., Gosset,G.. Expression of the melA gene from Rhizobium etli CFN42 in Escherichia coli and characterization of the encoded tyrosinase. Enzyme and Microbial Technology, 38 (6), 772-779.

Artículo

335 - de Anda,R., Lara,A.R., Hernandez,V., Hernandez-Montalvo,V., Gosset,G., Bolivar,F., Ramirez,O.T.. Replacement of the glucose phosphotransferase transport system by galactose permease reduces acetate accumulation and improves process performance of Escherichia coli for recombinant protein production without impairment of growth rate. Metabolic Engineering, 8 (3), 281-290.

Artículo

336 - Lagunas-Munoz,V.H., Cabrera-Valladares,N., Bolivar,F., Gosset,G., Martinez,A.. Optimum melanin production using recombinant Escherichia coli. Journal of Applied Microbiology, 101 (5), 1002-1008.

Artículo

337 - Lara,A.R., Leal,L., FLORES,N., Gosset,G., Bolivar,F., Ramirez,O.T.. Transcriptional and metabolic response of recombinant Escherichia coli to spatial dissolved oxygen tension gradients simulated in a scale-down system. Biotechnology and Bioengineering, 93 (2), 372-385.

Artículo

338 - Lara,A.R., Vazquez-Limon,C., Gosset,G., Bolivar,F., Lopez-Mungua,A., Ramirez,O.T.. Engineering Escherichia coli to improve culture performance and reduce formation of by-products during recombinant protein production under transient intermittent anaerobic conditions. Biotechnology and Bioengineering, 94 (6), 1164-1175.

Nacional

339 - Baez-Viveros,J.L., Osuna,J., Hernandez-Chavez,G., Soberon,X., Bolivar,F., Gosset,G.. Metabolic via engineering for the production of aromatic substances in Escherichia coli. Revista Latinoamericana de Microbiologia, 48 (2), 92.

Nacional

340 - Lagarda,G.G.. [Industrial microbiology]. Revista Latinoamericana de Microbiologia, 48 (2), 91-98. *

Divulgación

341 - Martinez,A., Rodriguez,M.E., Lopez-Munguia,A., Gosset,G.. ¿Etanol carburante a base de bagazo de caña?. Claridades Agropecuarias, 155, 22-25.

2005

Artículo

342 - FLORES,N., Flores,S., Escalante,A., de Anda,R., Leal,L., Malpica,R., Georgellis,D., Gosset,G., Bolivar,F.. Adaptation for fast growth on glucose by differential expression of central carbon metabolism and gal regulon genes in an Escherichia coli strain lacking the phosphoenolpyruvate:carbohydrate phosphotransferase system. Metabolic Engineering, 7 (2), 70-87.

Artículo

343 - Flores,S., FLORES,N., de Anda,R., Gonzalez,A., Escalante,A., Sigala,J.C., Gosset,G., Bolivar,F.. Nutrient-Scavenging Stress Response in an Escherichia coli Strain Lacking the Phosphoenolpyruvate:Carbohydrate Phosphotransferase System, as Explored by Gene Expression Profile Analysis. Journal of Molecular Microbiology and Biotechnology, 10 (1), 51-63.

Revisión

344 - Gosset,G.. Improvement of Escherichia coli production strains by modification of the phosphoenolpyruvate:sugar phosphotransferase system. Microbial Cell Factories, 4 (1), 14.

Artículo

345 - Sandoval-Basurto,E.A., Gosset,G., Bolivar,F., Ramirez,O.T.. Culture of Escherichia coli under dissolved oxygen gradients simulated in a two-compartment scale-down system: Metabolic response and production of recombinant protein. Biotechnology and Bioengineering, 89 (4), 453-463.

Artículo

346 - Zhang,Z., Gosset,G., Barabote,R., Gonzalez,C.S., Cuevas,W.A., Saier,M.H.,Jr.. Functional Interactions between the Carbon and Iron Utilization Regulators, Crp and Fur, in Escherichia coli. Journal of Bacteriology, 187 (3), 980-990.

Internacional

347 - Chavez-Bejar,M., Martinez,A., Bolivar,F., Gosset,G.. Metabolic pathway engineering for microbial production of aromatic amino acids. Research Advances in Food Science. 11-20, Kerala: Research Signpost.

2004

Artículo

348 - Baez-Viveros,J.L., Osuna,J., Hernandez-Chavez,G., Soberon,X., Bolivar,F., Gosset,G.. Metabolic engineering and protein directed evolution increase the yield of L-phenylalanine synthesized from glucose in Escherichia coli. Biotechnology and Bioengineering, 87 (4), 516-524.

Artículo

349 - Escalante,A., Rodriguez,M.E., Martinez,A., Lopez-Munguia,A., Bolivar,F., Gosset,G.. Characterization of bacterial diversity in Pulque, a traditional Mexican alcoholic fermented beverage, as determined by 16S rDNA analysis. Fems Microbiology Letters, 235 (2), 273-279.

Artículo

350 - FLORES,N., de Anda,R., Flores,S., Escalante,A., Hernandez,G., Martinez,A., Ramirez,O.T., Gosset,G., Bolivar,F.. Role of Pyruvate Oxidase in Escherichia coli Strains Lacking the Phosphoenolpyruvate:Carbohydrate Phosphotransferase System. Journal of Molecular Microbiology and Biotechnology, 8 (4), 209-221.

Artículo

351 - Flores,S., Anda-Herrera,R., Gosset,G., Bolivar,F.G.. Growth-rate recovery of Escherichia coli cultures carrying a multicopy plasmid, by engineering of the pentose-phosphate pathway. Biotechnology and Bioengineering, 87 (4), 485-494.

Artículo

352 - Garay-Arroyo,A., Covarrubias,A.A., Clark,I., Nino,I., Gosset,G., Martinez,A.. Response to different environmental stress conditions of industrial and laboratory Saccharomyces cerevisiae strains. Applied Microbiology and Biotechnology, 63 (6), 734-741.

Artículo

353 - Gosset,G., Zhang,Z., Nayyar,S., Cuevas,W.A., Saier,M.H.,Jr.. Transcriptome Analysis of Crp-Dependent Catabolite Control of Gene Expression in Escherichia coli. Journal of Bacteriology, 186 (11), 3516-3524.

Nacional

354 - Gosset,G., Bolivar,F.. Ingenieria celular microbiana. Fundamentos y casos exitosos de la biotecnologia moderna. 219-247, Mexico. *

Internacional

355 - Le Borgne,S., Bolivar,F., Gosset,G.. Plasmid Vectors for Marker-Free Chromosomal Insertion of Genetic Material in Escherichia coli. Recombinant gene expression : reviews and protocols. Methods in molecular biology (Clifton, N.J.), 135-144.

Nacional

356 - Escalante-Lozada,A, Gosset-Lagarda,G, Martinez-Jimenez,A., Bolivar-Zapata,F. Soil bacterial diversity: Microbial culture-independent methods of study and biotechnological implications. Agrociencia, 38 (6), 583-592.

2003

Artículo

357 - Hernandez-Montalvo,V., Martinez,A., Bolivar,F., Valle,F., Gosset,G.. Expression of galP and glk in a Escherichia coli PTS mutant restores glucose transport and increases glycolytic flux to fermentation products. Biotechnology and Bioengineering, 83 (6), 687-694.

Nacional

358 - Gosset,G., Bolivar,F.. Ingeniería celular en microorganismos. Fronteras de la Biología en los Inicios del Siglo XXI. Módulo VII. 5-34, Mexico,D.F:.

2002

Artículo

359 - Flores,S., Gosset,G., FLORES,N., de Graaf,A.A., Bolivar,F.. Analysis of carbon metabolism in Escherichia coli strains with an inactive phosphotransferase system by 13C labelling and NMR spectroscopy. Metabolic Engineering, 4 (2), 124-137.

Divulgación

360 - Martinez Jimenez,A., Bolivar-Zapata, F, Gosset Lagarda,G.. Biotecnologia energetica sustentable: etanol carburante para el transporte. Revista Universidad de Mexico, 617.

2001

Artículo

361 - Baez,J.L., Bolivar,F., Gosset,G.. Determination of 3-deoxy-D-arabino-heptulosonate 7-phosphate productivity and yield from glucose in Escherichia coli devoid of the glucose phosphotransferase transport system. Biotechnology and Bioengineering, 73 (6), 530-535.

Revisión

362 - Balbas,P., Gosset,G.. Chromosomal editing in Escherichia coli. Vectors for DNA integration and excision. Molecular Biotechnology, 19 (1), 1-12.

Artículo

363 - Gosset,G., Bonner,C.A., Jensen,R.A.. Microbial Origin of Plant-Type 2-Keto-3-Deoxy-D-arabino-Heptulosonate 7-Phosphate Synthases, Exemplified by the Chorismate- and Tryptophan-Regulated Enzyme from Xanthomonas campestris. Journal of Bacteriology, 183 (13), 4061-4070.

Artículo

364 - Hernandez-Montalvo,V., Valle,F., Bolivar,F., Gosset,G.. Characterization of sugar mixtures utilization by an Escherichia coli mutant devoid of the phosphotransferase system. Applied Microbiology and Biotechnology, 57 (1-2), 186-191.

Artículo

365 - Le Borgne,S., Palmeros,B., Bolivar,F., Gosset,G.. Improvement of the pBRINT-Ts plasmid family to obtain marker-free chromosomal insertion of cloned DNA in E. coli. Biotechniques, 30 (2), 252-256.

2000

Artículo

366 - Cruz,N., Le Borgne,S., Hernandez-Chavez,G., Gosset,G., Valle,F., Bolivar,F.. Engineering the Escherichia coli outer membrane protein OmpC for metal bioadsorption. Biotechnology Letters, 22 (7), 623-629.

Artículo

367 - Palmeros,B., Wild,J., Szybalski,W., Le Borgne,S., Hernandez-Chavez,G., Gosset,G., Valle,F., Bolivar,F.. A family of removable cassettes designed to obtain antibiotic-resistance-free genomic modifications of Escherichia coli and other bacteria. Gene, 247 (1-2), 255-264.

1999

Internacional

368 - LaDuca,R.J., Berry,A., Chotani,G., Dodge,T., Gosset,G., Valle,F., Liao,J., Xiao,J., Power,S.. Metabolic Pathway Engineering of Aromatic Compounds. Manual of industrial microbiology and biotechnology. 605-615, 2, Washington, D.C.

1998

Artículo

369 - Le Borgne,S., Palmeros,B., Valle,F., Bolivar,F., Gosset,G.. pBRINT-Ts: a plasmid family with a temperature-sensitive replicon, designed for chromosomal integration into the lacZ gene of Escherichia coli. Gene, 223 (1-2), 213-219.

1996

Artículo

370 - Gosset,G., Yong-Xiao,J., Berry,A.. A direct comparison of approaches for increasing carbon flow to aromatic biosynthesis in Escherichia coli. Journal of Industrial Microbiology, 17 (1), 47-52.

1994

Artículo

371 - Olmos,J., Cruz,N., Sanchez,M., Lopez,M., Balbas,P., Gosset,G., Valle,F., Bolivar,F.. Production in Escherichia coli of a rat chimeric proinsulin polypeptide carrying human A and B chains and its preparative chromatography. Journal of Biotechnology, 38 (1), 89-96.

Artículo

372 - Pfister,C.U., Duval,M., Godbillon,J., Gosset,G., Gygax,D., Marfil,F., Sioufi,A., Winkler,B.. Development, application and comparison of an enzyme immunoassay and a high-performance liquid chromatography method for the determination of the aromatase inhibitor CGS 20,267 in biological fluids. Journal of Pharmaceutical Sciences, 83 (4), 520-524. *

1993

Artículo

373 - Gosset,G., de Anda,R., Cruz,N., Martinez,A., Quintero,R., Bolivar,F.. Recombinant protein production in cultures of an Escherichia coli trp- strain. Applied Microbiology and Biotechnology, 39 (4-5), 541-546.

374 - Gosset Lagarda, Guillermo. Insulina humana : produccion por tecnicas de DNA recombinante . Instituto de Biotecnologia, Doctorado en Biotecnologia, UNAM.

Asesor: Nova Ojeda, Angel, Valle Baheza, Fernando

1992

Artículo

375 - Cruz,N., Lopez,M., Estrada,G., Alvarado,X., de Anda,R., Balbas,P., Gosset,G., Bolivar,F.. Preparative isolation of recombinant human insulin-A chain by ion exchange chromatography. Journal Of Liquid Chromatography, 15 (13), 2311-2324.

1990

Artículo

376 - Cruz,N., Antonio,S., de Anda,R., Gosset,G., Bolivar,F.. Preparative isolation by high performance liquid chromatography of human insulin B chain produced in Escherichia coli. Journal Of Liquid Chromatography, 13 (8), 1517-1528.

1989

Artículo

377 - Gosset,G., Merino,E., Recillas,F., Oliver,G., Becerril,B., Bolivar,F.. Amino acid sequence analysis of the glutamate synthase enzyme from Escherichia coli K-12. Protein sequences & data analysis, 2 (1), 9-16.

Artículo

378 - Puente,J.L., Alvarez-Scherer,V., Gosset,G., Calva,E.. Comparative analysis of the Salmonella typhi and Escherichia coli ompC genes. Gene, 83 (2), 197-206.

1988

379 - Gosset Lagarda, Guillermo. Caracterizacion de los genes que codifican para la enzima glutamato Escherichia coli K12 . Centro de Investigacion sobre Ingenieria Genetica y Biotecnologia, Maestria en Investigacion Biomedica Basica, UNAM.

Asesor: Nova Ojeda, Angel, Valle Baheza, Fernando

1987

Artículo

380 - Oliver,G., Gosset,G., Sanchez-Pescador,R., Lozoya,E., Ku,L.M., FLORES,N., Becerril,B., Valle,F., Bolivar,F.. Determination of the nucleotide sequence for the glutamate synthase structural genes of Escherichia coli K-12. Gene, 60 (1), 1-11.

1986

Artículo

381 - Valle,F., Gosset,G., Tenorio,B., Oliver,G., Bolivar,F.. Characterization of the regulatory region of the Escherichia coli penicillin acylase structural gene. Gene, 50 (1-3), 119-122.

382 - Gosset Lagarda, Guillermo. Aislamiento y secuencia nucleotidica de la region reguladora del gene estructural de la enzima penicilino amidasa de E. Coli . Escuela de Biologia, Licenciatura en Biología, Universidad Autonoma de Guadalajara. *

Asesor: Nova Ojeda, Angel, Valle Baheza, Fernando

1985

Artículo

383 - Oliver,G., Valle,F., Rosetti,F., Gomez-Pedrozo,M., Santamaria,P., Gosset,G., Bolivar,F.. A common precursor for the two subunits of the penicillin acylase from Escherichia coli ATCC11105. Gene, 40 (1), 9-14.

guillermo.gosset@ibt.unam.mx

Líder Académico

Responsable del consorcio

Grupo del Dr. Guillermo Gosset

Dr. Guillermo Gosset Lagarda Investigador Titular C Tiempo Completo Departamento de Ingeniería Celular y Biocatálisis

Doctorado

Maestría

Licenciatura

Pide tu deseo.

Protocolo para la atención integral de casos de violencia por razones de género en la UNAM. (PDF).

S.O.S.

Información Legal.

Convocatorias de Concurso de Oposición Abierto Vigentes.

UNAM - Ligas de interés.

Sistemas IBt - UNAM.

Dr. Guillermo Gosset Lagarda
Investigador Titular C Tiempo Completo
Departamento de Ingeniería Celular y Biocatálisis