Instituto de Biotecnologia UNAM

Grupo de la Dra. Claudia Lydia Treviño



Fertilization is a fundamental process that produces a unique individual and allows perpetuation of species with sexual reproduction. The interaction and the molecular dialogue established between the gametes is a matter of intense study. Spermatozoa are cells specially designed to reach, recognize and fuse to the oocyte. To perform these tasks spermatozoa must be prepared to face a constantly changing environment and to overcome several physical barriers. Since they are basically transcriptionally and transductionally silent, they rely profoundly in diverse signaling mechanisms to orient themselves and adjust to challenging conditions. After cell differentiation in the testis, spermatozoa continue maturation as they pass through the epididymis and motility is activated when they enter the female tract. Sperm capacitation also takes place in the female tract, it encompasses a series of modifications that further habilitate sperm to undergo the acrosome reaction (AR), an exocytotic event that allows spermatozoa to penetrate the outer layers of the oocyte and fuse with it. Cell signaling and ion transport are closely related, this type of signaling is particularly important in sperm cells since they lack protein synthesis. Ca2+ is a critical signaling molecule that participates in different cellular process acting at diverse spatial-temporal environments and it is also pivotal for sperm physiology. Our lab is interested in understanding how environmental cues can be translated via Ca2+ changes into physiological sperm responses. We center our efforts on the human model, focusing on the roles ion channels play on various sperm functions.

x

Dra. Claudia Lydia Trevio
Coordinador General de Docencia
Investigador
Tutor de Maestra y Doctorado
Dr. Julio Csar Chvez
Investigador
Dra. Ana Laura Gonzalez
Postdoctoral
M.C. Paulina Torres
Tcnico Acadmico
Lic. Nancy Barrera
Estudiante
M.C. Linda Valeria Castillo
Estudiante
T.L. Diana Laura Lobato
Estudiante
M.C. Jose Arturo Matamoros
Estudiante
Tec. Mariana Beatriz Olivares
Estudiante
Lic. Julissa Sols
Estudiante
Ing. Jos Emiliano Velzquez
Estudiante


UNAM | UNAM
Morelos
| Site Map | Virtual Biotechnology Library | About us | Services | email | Publications
Graduate Studies | IBT Seminars | Personnel | Library | Books and on line documents | Localization | SiBioTec | Main Page
1299 : 11184