Instituto de Biotecnologia UNAM

Grupo del Dr. Arnaud Jacques Marcel Ronceret

Cytogenomics of meiosis

Our research focuses on the molecular basis of the regulation of meiotic chromosome behavior. Meiosis is a crucial step in sexuality that allows new genomic combinations (through recombination) and half the genome size. During meiosis the genome actively remodels itself. These distinct configurations have been cytogenetically coined as distinct meiotic stages. We want to investigate what control these dramatic and dynamic conformational changes. We are exploring the knowledge gap between DNA genomic sequence, chromosome conformation structure changes and how the meiotic genome is organized in three dimensions. To do so, we are using plants such as maize (Zea mays), an historical model in cytogenetic studies whose genome sequence is known. In addition, understanding and controlling meiosis in an important crop such as maize is expected to have tremendous impact on breeding programs that could revolutionize maize production.

Research lines:

1.Understand the mechanisms that regulate the initiation of meiotic recombination at the genomic and chromosomic level. To gain insights into the regulation of complex genome meiotic recombination initiation we are combining the advantages of the maize model, using classical molecular genetics and reverse genetics, and innovative approaches using proteomics, ChiP, Chromosome Conformation Capture (3C) and state of the art microscopy.

2.An applied aspect of the lab research will engineer maize sexuality to maintain ´hybrid vigor´ (heterosis). We want to valorize our maize non transgenic meiotic mutants collection to form an apomeiotic maize, the first step for an apomictic maize that could propagate heterosis (Ronceret and Vielle-Calzada 2015).

Dr. Arnaud Jacques Marcel Ronceret
Investigador
Tutor de Maestría y Doctorado
Dr. Santiago Valentin Galvan
Postdoctoral
Biol. Elda Patricia Rueda
Técnico Académico
Ing. Itze Yiseth Aguila
Estudiante
Tania Guadalupe Alberto
Estudiante
IBQ. Osiris Bastida
Estudiante
Marilyn Cedillo
Estudiante
Jennifer Arleth Guerrero
Estudiante
Biol. Yared Gutiérrez
Estudiante
Misael Hernandez
Estudiante
Biol. José de Jesús Hernández
Estudiante
Ing. Xochilt Kimberly Meléndez
Estudiante
Marlet Morales
Estudiante
Ing. Maria Guadalupe Morales
Estudiante
Ing. Magdalena Ortega
Estudiante
IBQ. Alfredo Pérez
Estudiante
Katrin Thompson
Estudiante
Lic. Brian Alexander Cruz
Estancia Temporal
Lic. Javier Alberto Duana
Estancia Temporal
Ing. Samuel Nuñez
Estancia Temporal
Tec. Juan Martinez
Servicio Social
Tec. Lissette Suarez
Servicio Social


UNAM | UNAM
Morelos
| Site Map | Virtual Biotechnology Library | About us | Services | email | Publications
Graduate Studies | IBT Seminars | Personnel | Library | Books and on line documents | Localization | SiBioTec | Main Page
865 : 5842