IBT-UNAM : M.C. Leivi Clara Portugal Luna
M.C. Leivi Clara Portugal Luna
Tesis : Estudio del mecanismo de acción de las toxinas Cry de Bacillus thuringiensis en la linea celular CF-1 de insecto
Tutor : Dr. Roberto Carlos Munoz
Grupo de la Dra. Maria Alejandra Bravo
Teléfonos
Oficina +52 (777) 311-4900 ext 227 Laboratorio +52 (777) 329-1624 red UNAM 27624 +52 (777) 311-4900 ext 227
Premio Agrobio 2008, con la tesis de licenciatura Análisis de la Oligomerización e Inserción en membrana de las Toxinas Insecticidas Cry DE Bacillus thuringiensis Activadas a Diferente pH Agrobio México (2008)
Publicaciones recientes
Martinez-Solis,M. Pinos,D. Endo,H. Portugal,L. Sato,R. Herrero,S. Hernandez-Martinez,P.
2018. Role of Bacillus thuringiensis Cry1A toxins domains in the binding to the ABCC2 receptor from Spodoptera exigua Insect Biochemistry and Molecular Biology, 101, 47-56.
Soberon,M. Portugal,L. Garcia-Gomez,B.I. Sanchez,J. Onofre,J. Gomez,I. Pacheco,S. Bravo,A.
2018. Cell lines as models for the study of Cry toxins from Bacillus thuringiensis Insect Biochemistry and Molecular Biology, 93, 66-78.
Portugal,L. Munoz-Garay,C. Martinez-deCastro,D.L. Soberon,M. Bravo,A.
2017. Toxicity of Cry1A toxins from Bacillus thuringiensis to CF1 cells does not involve activation of adenylate cyclase/PKA signaling pathway Insect Biochemistry and Molecular Biology, 80, 21-31.
Portugal,L. Gringorten,J.L. Caputo,G.F. Soberon,M. Munoz-Garay,C. Bravo,A.
2014. Toxicity and mode of action of insecticidal Cry1A proteins from Bacillus thuringiensis in an insect cell line, CF-1 Peptides, 53, 292-299.
Carmona,D. Rodriguez-Almazan,C. Munoz-Garay,C. Portugal,L. Perez,C. de Maagd,R.A. Bakker,P. Soberon,M. Bravo,A.
2011. Dominant Negative Phenotype of Bacillus thuringiensis Cry1Ab, Cry11Aa and Cry4Ba Mutants Suggest Hetero-Oligomer Formation among Different Cry Toxins PLoS ONE, 6, e19952.
Munoz-Garay,C. Rodriguez-Almazan,C. Aguilar,J.N. Portugal,L. Gomez,I. Saab-Rincon,G. Soberon,M. Bravo,A.
2009. Oligomerization of Cry11Aa from Bacillus thuringiensis has an important role in toxicity against Aedes aegypti Applied and Environmental Microbiology, 75, 7548-7550 [Correction vol 79 (5) p 1762].
Munoz-Garay,C. Portugal,L. Pardo-Lopez,L. Jimenez-Juarez,N. Arenas,I. Gomez,I. Sanchez-Lopez,R. Arroyo,R. Holzenburg,A. Savva,C.G. Soberon,M. Bravo,A.
2009. Characterization of the mechanism of action of the genetically modified Cry1AbMod toxin that is active against Cry1Ab-resistant insects Biochimica Et Biophysica Acta-Biomembranes, 1788, 2229-2237.
Perez,C. Munoz-Garay,C. Portugal,L.C. Sanchez,J. Gill,S.S. Soberon,M. Bravo,A.
2007. Bacillus thuringiensis ssp. israelensis Cyt1Aa enhances activity of Cry11Aa toxin by facilitating the formation of a pre-pore oligomeric structure Cellular Microbiology, 9, 2931-2937.
Bravo,A. Martinez-de-Castro,D.L. Sanchez,J. Munoz-Garay,C. Matus,V. Canton,P.E. Lopez-Diaz,J. Portugal,L. Mendoza,G. Soberon,M. 2014. Mode of action of Bacillus thuringiensis toxins and their use in transgenic crops to control insect pests en: Biotechnology: beyond borders. CSIR National Chemical Laboratory. pags. 122-134
Estudiante de Doctorado en Ciencias Bioquímicas