. Instituto de Biotecnologia UNAM

IBT-UNAM : Dr. Ernesto Mendez Salinas

Dr. Ernesto Mendez Salinas

ex-colaborador y/o ex-alumno
Nivel I del SNI
Grupo del Dr. Carlos Federico Arias
Teléfonos
Oficina +52 (777) 311-4900 ext 239

Laboratorio +52 (777) 329-1612
desde la CDMX 562-27612
red UNAM 27612
+52 (777) 311-4900 ext 239

- Licenciatura: Químico Farmaceutico Biologo, UNAM (1985)
- Maestría: en Investigacion Biomedica Basica, UNAM (1990)
- Doctorado: en Biotecnología, IBt-UNAM (1993)
- Mencion honorífica en examen de Maestría
- Mencion honorífica en examen Doctorado
- Medalla "Gabino Barreda"-UNAM por estudios de Doctorado (1998)
- Universidad de Washington, St. Louis, MO, E.U.A(1995)

Premio Bienal Funsalud en Enfermedades Gastrointestinales (NADRO) Fundación Mexicana para la Salud (2002)
Premio Bienal FUNSALUD en Infecciones Gastrointestinales Fundación Mexicana para la Salud (2000)

Publicaciones recientes

Toh,Y. Harper,J. Dryden,K.A. Yeager,M. Arias,C.F. Mendez,E. Tao,Y.J. 2016. Crystal Structure of the Human Astrovirus Capsid Protein Journal of Virology, 90, 9008-9017.

Murillo,A. Vera-Estrella,R. Barkla,B.J. Mendez,E. Arias,C.F. 2015. Identification of host cell factors associated with astrovirus replication in Caco-2 cells Journal of Virology, 89, 10359-10370.

Mendez,E. Munoz-Yanez,C. Sanchez-SanMartin,C. Aguirre-Crespo,G. Banos-Lara,M.D. Gutierrez,M. Espinosa,R. Acevedo,Y. Arias,C.F. Lopez,S. 2014. Characterization of human astrovirus cell entry Journal of Virology, 88, 2452-2460.

Mateo,R. Nagamine,C.M. Spagnolo,J. Mendez,E. Rahe,M. Gale,M., Jr. Yuan,J. Kirkegaard,K. 2013. Inhibition of cellular autophagy deranges dengue virion maturation Journal of Virology, 87, 1312-1321.

Dryden,K.A. Tihova,M. Nowotny,N. Matsui,S.M. Mendez,E. Yeager,M. 2012. Immature and mature human astrovirus: structure, conformational changes, and similarities to hepatitis E virus Journal of Molecular Biology, 422, 650-658.

Landa-Cardena,A. Morales-Romero,J. Garcia-Roman,R. Cobian-Guemes,A.G. Mendez,E. Ortiz-Leon,C. Pitalua-Cortes,F. Mora,S.I. Montero,H. 2012. Clinical characteristics and genetic variability of human rhinovirus in Mexico Viruses, 4, 200-210.

Velazquez-Moctezuma,R. Banos-Lara,M.D. Acevedo,Y. Mendez,E. 2012. Alternative cell lines to improve the rescue of infectious human astrovirus from a cDNA clone Journal of Virological Methods, 179, 295-302.

Dong,J. Dong,L. Mendez,E. Tao,Y. 2011. Crystal structure of the human astrovirus capsid spike Proceedings of the National Academy of Sciences of the United States of America, 108, 12681-12686.

Banos-Lara,M.D. Mendez,E. 2010. Role of individual caspases induced by astrovirus on the processing of its structural protein and its release from the cell through a non-lytic mechanism Virology, 401, 322-32.

Sarmiento,R.E. Arias,C.F. Mendez,E. Gomez,B. 2009. Characterization of a persistent respiratory syncytial virus showing a low-fusogenic activity associated to an impaired F protein Virus Research, 139, 39-47.

Espinosa,A.C. Mazari-Hiriart,M. Espinosa,R. Maruri-Avidal,L. Mendez,E. Arias,C.F. 2008. Infectivity and genome persistence of rotavirus and astrovirus in groundwater and surface water Water Research, 42, 2618-2628.

Mendez,E. Aguirre-Crespo,G. Zavala,G. Arias,C.F. 2007. Association of the astrovirus structural protein VP90 with membranes plays a role in virus morphogenesis Journal of Virology, 81, 10649-10658.

Mendez,E. Salas-Ocampo,E. Arias,C.F. 2004. Caspases mediate processing of the capsid precursor and cell release of human astroviruses Journal of Virology, 78, 8601-8608.

Mendez,E. Salas-Ocampo,M.P. Munguia,M.E. Arias,C.F. 2003. Protein products of the open reading frames encoding nonstructural proteins of human astrovirus serotype 8 Journal of Virology, 77, 11378-11384.

Arias,C.F. Isa,P. Guerrero,C. Mendez,E. Zarate,S. Lopez,T. Espinosa,R. Romero,P. Lopez,S. 2002. Molecular biology of rotavirus cell entry Archives of Medical Research, 33, 356-361.

Mendez,E. Fernandez-Luna,T. Lopez,S. Mendez-Toss,M. Arias,C.F. 2002. Proteolytic Processing of a Serotype 8 Human Astrovirus ORF2 Polyprotein Journal of Virology, 76, 7996-8002.

Guerrero,C.A. Bouyssounade,D. Zarate,S. Isa,P. Lopez,T. Espinosa,R. Romero,P. Mendez,E. Lopez,S. Arias,C.F. 2002. Heat shock cognate protein 70 is involved in rotavirus cell entry Journal of Virology, 76, 4096-4102.

Myers,T.M. Kolupaeva,V.G. Mendez,E. Baginski,S.G. Frolov,I. Hellen,C.U. Rice,C.M. 2001. Efficient translation initiation is required for replication of bovine viral diarrhea virus subgenomic replicons Journal of Virology, 75, 4226-4238 * .

Zarate,S. Espinosa,R. Romero,P. Mendez,E. Arias,C.F. Lopez,S. 2000. The VP5 domain of VP4 can mediate attachment of rotaviruses to cells Journal of Virology, 74, 593-599.

Guerrero,C.A. Mendez,E. Zarate,S. Isa,P. Lopez,S. Arias,C.F. 2000. Integrin alpha(v)beta(3) mediates rotavirus cell entry Proceedings of the National Academy of Sciences of the United States of America, 97, 14644-14649.

Lopez,S. Espinosa,R. Isa,P. Merchant,M.T. Zarate,S. Mendez,E. Arias,C.F. 2000. Characterization of a monoclonal antibody directed to the surface of MA104 cells that blocks the infectivity of rotaviruses Virology, 273, 160-168.

Mendez-Toss,M. Romero-Guido,P. Munguia,M.E. Mendez,E. Arias,C.F. 2000. Molecular analysis of a serotype 8 human astrovirus genome Journal of General Virology, 81, 2891-2897.

Mendez,E. Lopez,S. Cuadras,M.A. Romero,P. Arias,C.F. 1999. Entry of rotaviruses is a multistep process Virology, 263, 450-459.

Mendez,E. Ruggli,N. Collett,M.S. Rice,C.M. 1998. Infectious bovine viral diarrhea virus (strain NADL) RNA from stable cDNA clones: a cellular insert determines NS3 production and viral cytopathogenicity Journal of Virology, 72, 4737-4745.

Cuadras,M.A. Mendez,E. Arias,C.F. Lopez,S. 1998. A new cysteine in rotavirus VP4 participates in the formation of an alternate disulfide bond Journal of General Virology, 79, 2673-2677.

Xu,J. Mendez,E. Caron,P.R. Lin,C. Murcko,M.A. Collett,M.S. Rice,C.M. 1997. Bovine viral diarrhea virus NS3 serine proteinase: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replication Journal of Virology, 71, 5312-5322.

Mendez,E. Arias,C.F. Lopez,S. 1996. Interactions between the two surface proteins of rotavirus may alter the receptor-binding specificity of the virus Journal of Virology, 70, 1218-1222.

Mendez,E. Arias,C.F. Lopez,S. 1993. Binding to sialic acids is not an essential step for the entry of animal rotaviruses to epithelial cells in culture Journal of Virology, 67, 5253-5259.

Mendez,E. Arias,C.F. Lopez,S. 1992. Genomic rearrangements in human rotavirus strain Wa; analysis of rearranged RNA segment 7 Archives of Virology, 125, 331-338.

Lopez,S. Lopez,I. Romero,P. Mendez,E. Soberon,X. Arias,C.F. 1991. Rotavirus YM gene 4: analysis of its deduced amino acid sequence and prediction of the secondary structure of the VP4 protein Journal of Virology, 65, 3738-3745.

Mascarenhas,J.D. Linhares,A.C. Gabbay,Y.B. de Freitas,R.B. Mendez,E. Lopez,S. Arias,C.F. 1989. Naturally occurring serotype 2/subgroup II rotavirus reassortants in northern Brazil Virus Research, 14, 235-240.

Lopez,S. Arias,C.F. Mendez,E. Espejo,R.T. 1986. Conservation in rotaviruses of the protein region containing the two sites associated with trypsin enhancement of infectivity Virology, 154, 224-227 * .

Mendez,E. Murillo,A. Velazquez,R. Burnham,A. Arias,C.F. 2013. Replication Cycle of Astroviruses en: Schultz-Cherry,S. Astrovirus Research. Springer New York. pags. 19-45

Mendez,E. Arias,C.F. 2013. Astroviruses en: Griffin,D.E. Field's Virology 6 ed.. Philadelphia. Wolters Kluwer Health/Lippincott Williams & Wilkins,.

Bosch,A. Guix,S. Krishna,N.K. Mendez,E. Monroe,S.S. Pantin-Jackwood,M. Schultz-Cherry,S. 2012. 953 en: King,A.M.Q. Virus Taxonomy: IXth Report of the International Committee on Taxonomy of Viruses. Elsevier. 960

Mendez,E. Arias,C.F. 2012. Astroviruses en: Hayden,F.G. Clinical Virology. ASM Press.

Mendez,E. Arias,C.F. 2009. 50 en: Hayden,F.G. Clinical Virology. ASM Press. pags. 1145-1153

Mendez-Salinas,E. Arias-Ortiz,C.F. 2008. Cómo los virus modulan y aprovechan la muerte celular programada en: *agustin Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 14. Mexico, D.F.. UNAM. pags. 159-166

Mendez,E. Arias,C.F. 2006. Astroviruses en: Griffin,D.E. Field's Virology. Philadelphia. Wolters Kluwer Health/Lippincott Williams & Wilkins,. pags. 981-1000

Geigenmuller,U. Mendez,E. Matsui,S.M. 2003. Studies on the molecular biology of human astrovirus en: Gray,J. Perspectives in Medical Virology. Elsevier. pags. 573-586

Arias,C.F. Guerrero,C.A. Mendez,E. Zarate,S. Isa,P. Espinosa,R. Romero,P. Lopez,S. 2001. Early events of rotavirus infection: the search for the receptor(s) en: Goode,J.A. Gastroenteritis Viruses. pags. 47-60 discussion 603.

Divulgación

Mendez,E. 2006. The release and entrance of human astrovirus in its host cell are promoted by cellular origin proteases Revista Latinoamericana de Microbiologia, 48, 198-199.

* Indica publicación con otra institución de adscripción